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Expert Opinion on Investigational Drugs Volume 18, 2009 - Issue 2
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Key Paper Evaluation

HIF-1α inhibition as a novel mechanism of cardiac glycosides in cancer therapeutics

Evaluation of: Zhang H, Qian DZ, Tan YS, et al. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth. Proc Natl Acad Sci USA 2008;105:19579-86

Jianqing Lin Department of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, CRBI 1M50, 1650 Orleans Street, Baltimore, Maryland, 21231, USA +1 410 614 3977; +1 410 614 3977; [email protected]
&
Michael A Carducci Department of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, CRBI 1M50, 1650 Orleans Street, Baltimore, Maryland, 21231, USA +1 410 614 3977; +1 410 614 3977; [email protected]
Pages 241-243 | Published online: 21 Jan 2009

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Natalia Prevarskaya, Roman Skryma & Yaroslav Shuba. (2013) Targeting Ca2+ transport in cancer: close reality or long perspective?. Expert Opinion on Therapeutic Targets 17:3, pages 225-241.
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Articles from other publishers (4)

Honey Pavithran, Angelina Job Kolady & Ranjith Kumavath. 2023. Computational Methods in Drug Discovery and Repurposing for Cancer Therapy. Computational Methods in Drug Discovery and Repurposing for Cancer Therapy 237 258 .
Evelyn M. Flahavan, Linda Sharp, Kathleen Bennett & Thomas I. Barron. (2014) A cohort study of digoxin exposure and mortality in men with prostate cancer. BJU International 113:2, pages 236-245.
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Michael E. Jung & Mikhail Guzaev. (2013) Studies Toward the Enantiospecific Total Synthesis of Rhodexin A. The Journal of Organic Chemistry 78:15, pages 7518-7526.
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Michael E. Jung & Dongwon Yoo. (2011) First Total Synthesis of Rhodexin A. Organic Letters 13:10, pages 2698-2701.
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