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New antifungal therapies for the treatment of onychomycosis

, MD & , MD MPH
Pages 727-734 | Published online: 09 May 2009

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Namrata Prajapati, Dilip Sharma, Pankaj Ashok Bidve, Deepak Chouhan, Meghana Allani, Sagar kumar Patel, Moumita Ghosh Chowdhury, Amit Shard & Vinod Tiwari. (2023) Glucose regulation by newly synthesized boronic acid functionalized molecules as dipeptidyl peptidase IV inhibitor: a potential compound for therapeutic intervention in hyperglycaemia. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
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Min Seok Kim, Ji Yun Jung, Eun Byul Cho, Eun Joo Park, Kwang Ho Kim & Kwang Joong Kim. (2016) The effectiveness of 1,064-nm long-pulsed Nd:YAG laser in the treatment of severe onychomycosis. Journal of Cosmetic and Laser Therapy 18:6, pages 317-322.
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Purnima Kataria, Gajanand Sharma, Kanika Thakur, Vikas Bansal, Sunil Dogra & Om Prakash Katare. (2016) Emergence of nail lacquers as potential transungual delivery system in the management of onchomycosis. Expert Opinion on Drug Delivery 13:7, pages 937-952.
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Boni E Elewski. (2013) Efinaconazole 10% solution: a new topical antifungal therapy for onychomycosis. Expert Review of Dermatology 8:4, pages 347-356.
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Anroop B. Nair, Kishan Singh, Pottathil Shinu, Sree Harsha & Bandar E. Al-Dhubiab. (2013) A comprehensive study to evaluate the effect of constant low voltage iontophoresis on transungual delivery. Drug Development and Industrial Pharmacy 39:5, pages 807-815.
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Articles from other publishers (34)

Joana Baier, Björn Jansen, Arlette Wenzel-Storjohann, Deniz Tasdemir & Christian Peifer. (2023) Novel Henna-Related Naphthazarine Photosensitizers for an Effective Photodynamic Therapy of Onychomycosis. ACS Pharmacology & Translational Science 6:12, pages 1958-1971.
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Zahra Kazeminejad, Mahrokh Marzi, Abolfazl Shiroudi, Seyed Amin Kouhpayeh, Mojtaba Farjam & Elham Zarenezhad. (2022) Novel 1, 2, 4-Triazoles as Antifungal Agents. BioMed Research International 2022, pages 1-39.
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Tainá Kreutz, Sheila Porto de Matos & Letícia Scherer Koester. (2020) Recent Patents on Permeation Enhancers for Drug Delivery Through Nails. Recent Patents on Drug Delivery & Formulation 13:3, pages 203-218.
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Elizabeth Yim, Leyre A. Falto‐Aizpurua, Jennifer Ledon & Keyvan Nouri. 2019. Pediatric Dermatologic Surgery. Pediatric Dermatologic Surgery 229 240 .
Raed M. Al-Zoubi, Mazhar S. Al-Zoubi, Khaled T. Jaradat & Robert McDonald. (2017) Design, Synthesis and X-ray Crystal Structure of Iodinated Benzoboroxole Derivatives by Consecutive Metal-Iodine Exchange of 3,4,5-Triiodoanisole. European Journal of Organic Chemistry 2017:38, pages 5800-5808.
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Purva Thatai & Bharti Sapra. (2017) Transungual Gel of Terbinafine Hydrochloride for the Management of Onychomycosis: Formulation, Optimization, and Evaluation. AAPS PharmSciTech 18:6, pages 2316-2328.
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Shinichi Watanabe, Hiroshi Kishida & Akihiro Okubo. (2017) Efficacy and safety of luliconazole 5% nail solution for the treatment of onychomycosis: A multicenter, double-blind, randomized phase III study. The Journal of Dermatology 44:7, pages 753-759.
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Ivana Kuklová, Jiřina Stará & Kateřina Sedláková. (2016) Current epidemiology and the treatment options of dermatophyte infection. Dermatologie pro praxi 10:2, pages 76-79.
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Aditya K. Gupta, Deanne Daigle & Jessie L. Carviel. (2016) The role of biofilms in onychomycosis. Journal of the American Academy of Dermatology 74:6, pages 1241-1246.
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Nida Akhtar, Hemlata Sharma & Kamla Pathak. (2016) Onychomycosis: Potential of Nail Lacquers in Transungual Delivery of Antifungals. Scientifica 2016, pages 1-12.
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Bryan MarkinsonBryan Caldwell. (2015) Efinaconazole Topical Solution, 10%. Journal of the American Podiatric Medical Association 105:5, pages 407-411.
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Anja Täuber & Christel C. Müller-Goymann. (2015) In vitro permeation and penetration of ciclopirox olamine from poloxamer 407-based formulations – comparison of isolated human stratum corneum, bovine hoof plates and keratin films. International Journal of Pharmaceutics 489:1-2, pages 73-82.
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R. Moutran, I. Maatouk & J. Hélou. (2015) Diabetic neuropathy and Nd-YAG (1064 nm) laser for onychomycosis: be careful. Journal of the European Academy of Dermatology and Venereology 29:6, pages 1239-1240.
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Jorge Cornejo-Garrido, Martha Salinas-Sandoval, Arely Díaz-López, Patricia Jácquez-Ríos, Myriam Arriaga-Alba & Cynthia Ordaz-Pichardo. (2015) In vitro and in vivo antifungal activity, liver profile test, and mutagenic activity of five plants used in traditional Mexican medicine. Revista Brasileira de Farmacognosia 25:1, pages 22-28.
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Anil K. Bhatta, Xin Huang, Uma Keyal & Jun Jing Zhao. (2014) Laser treatment for onychomycosis: a review. Mycoses 57:12, pages 734-740.
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Melodie Young. (2014) Onychomycosis. Journal of the Dermatology Nurses' Association 6:5, pages 239-243.
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Anja Täuber & Christel C. Müller-Goymann. (2014) Comparison of the Antifungal Efficacy of Terbinafine Hydrochloride and Ciclopirox Olamine Containing Formulations against the Dermatophyte Trichophyton rubrum in an Infected Nail Plate Model . Molecular Pharmaceutics 11:7, pages 1991-1996.
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Minh Lam, Matthew L. Dimaano, Patricia Oyetakin-White, Mauricio A. Retuerto, Jyotsna Chandra, Pranab K. Mukherjee, Mahmoud A. Ghannoum, Kevin D. Cooper & Elma D. Baron. (2014) Silicon Phthalocyanine 4 Phototoxicity in Trichophyton rubrum. Antimicrobial Agents and Chemotherapy 58:6, pages 3029-3034.
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Boni E. Elewski, Phoebe Rich, Richard Pollak, David M. Pariser, Shinichi Watanabe, Hisato Senda, Chikara Ieda, Kathleen Smith, Radhakrishnan Pillai, Tage Ramakrishna & Jason T. Olin. (2013) Efinaconazole 10% solution in the treatment of toenail onychomycosis: Two phase III multicenter, randomized, double-blind studies. Journal of the American Academy of Dermatology 68:4, pages 600-608.
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B.E. Elewski, M.A. Ghannoum, P. Mayser, A.K. Gupta, H.-C. Korting, R.J. Shouey, D.R. Baker, P.A. Rich, M. Ling, S. Hugot, B. Damaj, J. Nyirady, K. Thangavelu, M. Notter, A. Parneix-Spake & B. Sigurgeirsson. (2013) Efficacy, safety and tolerability of topical terbinafine nail solution in patients with mild-to-moderate toenail onychomycosis: results from three randomized studies using double-blind vehicle-controlled and open-label active-controlled designs. Journal of the European Academy of Dermatology and Venereology 27:3, pages 287-294.
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Bhavesh S. Barot, Punit B. Parejiya, Hetal K. Patel, Dharmik M. Mehta & Pragna K. Shelat. (2012) Microemulsion-based antifungal gel delivery to nail for the treatment of onychomycosis: formulation, optimization, and efficacy studies. Drug Delivery and Translational Research 2:6, pages 463-476.
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Oke A. Anakwenze, Andrew H. Milby, Itai Gans, John J. Stern, Scott L. Levin & Keith L. Wapner. (2012) Foot and Ankle Infections: Diagnosis and Management. Journal of the American Academy of Orthopaedic Surgeons 20:11, pages 684-693.
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Aditya K. Gupta & Fiona C. Simpson. (2012) Medical devices for the treatment of onychomycosis. Dermatologic Therapy 25:6, pages 574-581.
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M. Pereiro FerreirósJr.Jr., F.J. García-Martínez & J. Alonso-González. (2012) Update on the Treatment of Superficial Mycoses. Actas Dermo-Sifiliográficas (English Edition) 103:9, pages 778-783.
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M. Pereiro FerreirósJr.Jr., F.J. García-Martínez & J. Alonso-González. (2012) Actualización en el tratamiento de las micosis cutáneas. Actas Dermo-Sifiliográficas 103:9, pages 778-783.
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Yolanda Gilaberte, Manuel Pablo Paz-Cristobal, Antonio Rezusta & Carmen Aspiroz. (2012) Terapia fotodin?mica antimicrobiana en dermatolog?a. Piel 27:5, pages 274-282.
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Malcolm D. Richardson & David W. Warnock. 2012. Fungal Infection. Fungal Infection 151 155 .
이시현, 박미연 & 안지영. (2012) Photodynamic Therapy with Methyl 5-aminolevulinic Acid for Treatment of Toenail Onychomycosis: the Efficacy and Safety. Korean Journal of Medical Mycology 17:1, pages 8-16.
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Bhavesh S. Barot, Punit B. Parejiya, Hetal K. Patel, Mukesh C. Gohel & Pragna K. Shelat. (2011) Microemulsion-Based Gel of Terbinafine for the Treatment of Onychomycosis: Optimization of Formulation Using D-Optimal Design. AAPS PharmSciTech 13:1, pages 184-192.
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L. Nogueiras-Nieto, J.L. Gómez-Amoza, M.B. Delgado-Charro & F.J. Otero-Espinar. (2011) Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof: Implications for drug delivery. Journal of Controlled Release 156:3, pages 337-344.
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Massimo Lurati, Florence Baudraz-Rosselet, Maxime Vernez, Phillip Spring, Olympia Bontems, Marina Fratti & Michel Monod. (2011) Efficacious Treatment of Non-Dermatophyte Mould Onychomycosis with Topical Amphotericin B. Dermatology 223:4, pages 289-292.
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Ezequiel D. Quiroga, María Gabriela Alvarez & Edgardo N. Durantini. (2010) Susceptibility of Candida albicans to photodynamic action of 5,10,15,20-tetra(4-N-methylpyridyl)porphyrin in different media. FEMS Immunology & Medical Microbiology 60:2, pages 123-131.
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Raed M. Al-Zoubi & Dennis G. Hall. (2010) Mild Silver(I)-Mediated Regioselective Iodination and Bromination of Arylboronic Acids. Organic Letters 12:11, pages 2480-2483.
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Oliverio Welsh, Lucio Vera-Cabrera & Esperanza Welsh. (2010) Onychomycosis. Clinics in Dermatology 28:2, pages 151-159.
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