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Volume 18, Issue 6

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 6 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 6 (2009)

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Perspective

Article

Current drugs and medical treatment algorithms in the management of acute decompensated heart failure

Filippos Triposkiadis MD, John T Parissis MD, Randall C Starling MD, John Skoularigis MD & George Louridas MD

Pages: 695-707

Published online: 09 May 2009

AbstractforCurrent drugs and medical treatment algorithms in the management of acute decompensated heart failure | Full Text | References | PDF (398.2 KB)

541 Views
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Reviews

Article

Progress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues

Nathaniel A Brown MD

Pages: 709-725

Published online: 09 May 2009

AbstractforProgress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues | Full Text | References | PDF (965 KB)

312 Views
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Article

New antifungal therapies for the treatment of onychomycosis

Sandeep Kumar MD & Alexa B Kimball MD MPH

Pages: 727-734

Published online: 09 May 2009

AbstractforNew antifungal therapies for the treatment of onychomycosis | Full Text | References | PDF (249.3 KB)

443 Views
39 CrossRef citations
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Article

Invasive candidiasis and candidemia: from current opinions to future perspectives

Maria JGT Rueping, Joerg-Janne Vehreschild & Oliver A Cornely

Pages: 735-748

Published online: 09 May 2009

AbstractforInvasive candidiasis and candidemia: from current opinions to future perspectives | Full Text | References | PDF (327.1 KB)

177 Views
27 CrossRef citations
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Article

Prostaglandin EP2 and EP4 receptor agonists in bone formation and bone healing: In vivo and in vitro evidence

Simon Graham, Zakareya Gamie, Ioannis Polyzois, Amir Ali Narvani, Kallirroi Tzafetta, Evgenios Tsiridis, Manolis Heliotis, Athanasios Mantalaris & Eleftherios Tsiridis

Pages: 749-766

Published online: 09 May 2009

AbstractforProstaglandin EP2 and EP4 receptor agonists in bone formation and bone healing: In vivo and in vitro evidence | Full Text | References | PDF (464.7 KB)

649 Views
37 CrossRef citations
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Article

Current investigational drugs for major depression

Shrinivas K Kulkarni PhD & Ashish Dhir PhD

Pages: 767-788

Published online: 09 May 2009

AbstractforCurrent investigational drugs for major depression | Full Text | References | PDF (1 MB)

691 Views
80 CrossRef citations
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Article

Therapeutic potential of novel glutamate receptor antagonists in migraine

Anna P Andreou & Peter J Goadsby

Pages: 789-803

Published online: 09 May 2009

AbstractforTherapeutic potential of novel glutamate receptor antagonists in migraine | Full Text | References | PDF (441.6 KB)

430 Views
60 CrossRef citations
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Article

New treatments for idiopathic thrombocytopenic purpura: rethinking old hypotheses

Donald M Arnold, Ishac Nazi & John G Kelton

Pages: 805-819

Published online: 09 May 2009

AbstractforNew treatments for idiopathic thrombocytopenic purpura: rethinking old hypotheses | Full Text | References | PDF (2 MB)

366 Views
15 CrossRef citations
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Drug Evaluations

Article

Sunitinib in solid tumors

Hui K Gan MD PhD, Bostjan Seruga MD MSc & Jennifer J Knox MD FRCPC MSc

Pages: 821-834

Published online: 20 May 2009

AbstractforSunitinib in solid tumors | Full Text | References | PDF (469.9 KB)

504 Views
90 CrossRef citations
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Article

Inhibition of dipeptidyl peptidase 4 by BI-1356, a new drug for the treatment of beta-cell failure in type 2 diabetes

Jørgen Rungby

Pages: 835-838

Published online: 09 May 2009

AbstractforInhibition of dipeptidyl peptidase 4 by BI-1356, a new drug for the treatment of beta-cell failure in type 2 diabetes | Full Text | References | PDF (194.9 KB)

227 Views
4 CrossRef citations
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Article

Ospemifene use in postmenopausal women

Luigi Gennari MD PhD, Daniela Merlotti MD, Fabrizio Valleggi MD & Ranuccio Nuti MD

Pages: 839-849

Published online: 25 May 2009

AbstractforOspemifene use in postmenopausal women | Full Text | References | PDF (278.4 KB)

225 Views
28 CrossRef citations
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Article

Degarelix for prostate cancer

Christian Doehn MD PhD, Martin Sommerauer & Dieter Jocham

Pages: 851-860

Published online: 20 May 2009

AbstractforDegarelix for prostate cancer | Full Text | References | PDF (272.9 KB)

327 Views
14 CrossRef citations
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Article

Tanespimycin: the opportunities and challenges of targeting heat shock protein 90

Charles Erlichman

Pages: 861-868

Published online: 25 May 2009

AbstractforTanespimycin: the opportunities and challenges of targeting heat shock protein 90 | Full Text | References | PDF (355 KB)

344 Views
56 CrossRef citations
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Key Paper Evaluation

Article

Mepolizumab for difficult-to-control asthma with persistent sputum eosinophilia

Evaluation of: Haldar P, Brightling CE, Hargadon B, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-84Nair P, Pizzichini MM, Kjarsgaard M, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-93

Sabina A Antoniu

Pages: 869-871

Published online: 09 May 2009

AbstractforMepolizumab for difficult-to-control asthma with persistent sputum eosinophilia | Full Text | References | PDF (175.6 KB)

347 Views
12 CrossRef citations
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Erratum

Article

Erratum

Page: 873

Published online: 25 May 2009

CitationforErratum | Full Text | PDF (85 KB)

241 Views
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