Citations (197)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (11)
Dzung N. Bui, Ly T. T. Nguyen, Le-Thu T. Nguyen, Ngoc T. N. Ngo, Phuong T. Tran, Hieu T. Nguyen, Linh T. N. Dang, Lien-Hoa D. Nguyen & Binh T. D. Trinh. (2023) Two new antidiabetic xanthones from the twigs of Garcinia oblongifolia. Natural Product Research 37:15, pages 2541-2550.
Read now
Read now
Quan Wang, Xue-Qi Fu & Qing-Chuan Zheng. (2020) Exploring the allosteric mechanism of protein tyrosine phosphatase 1B by molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics 38:13, pages 4040-4047.
Read now
Read now
Dong-Cheol Kim, Tran Minh Ha, Jae Hak Sohn, Joung Han Yim & Hyuncheol Oh. (2020) Protein tyrosine phosphatase 1B inhibitors from a marine-derived fungal strain aspergillus sp. SF-5929. Natural Product Research 34:5, pages 675-682.
Read now
Read now
Farshid Zargari, Maryam Lotfi, Omolbanin Shahraki, Zahra Nikfarjam & Jafar Shahraki. (2018) Flavonoids as potent allosteric inhibitors of protein tyrosine phosphatase 1B: molecular dynamics simulation and free energy calculation. Journal of Biomolecular Structure and Dynamics 36:15, pages 4126-4142.
Read now
Read now
Pradip D Patil, Umesh B Mahajan, Kalpesh R Patil, Sandip Chaudhari, Chandragouda R Patil, Yogeeta O Agrawal, Shreesh Ojha & Sameer N Goyal. (2017) Past and current perspective on new therapeutic targets for Type-II diabetes. Drug Design, Development and Therapy 11, pages 1567-1583.
Read now
Read now
Braham Na, Phi-Hung Nguyen, Bing-Tian Zhao, Quoc-Hung Vo, Byung Sun Min & Mi Hee Woo. (2016) Protein tyrosine phosphatase 1B (PTP1B) inhibitory activity and glucosidase inhibitory activity of compounds isolated from Agrimonia pilosa. Pharmaceutical Biology 54:3, pages 474-480.
Read now
Read now
Akhilesh Kumar Tamrakar, Chandan K Maurya & Amit K Rai. (2014) PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011 – 2014). Expert Opinion on Therapeutic Patents 24:10, pages 1101-1115.
Read now
Read now
Afshin Zarghi & Zahra Hajimahdi. (2013) Substituted oxadiazoles: a patent review (2010 – 2012). Expert Opinion on Therapeutic Patents 23:9, pages 1209-1232.
Read now
Read now
V.P. Veerapur, K.R. Prabhakar, M.R. Kandadi, K.K. Srinivasan & M.K. Unnikrishnan. (2010) Antidiabetic effect of Dodonaea viscosa aerial parts in high fat diet and low dose streptozotocin-induced type 2 diabetic rats: A mechanistic approach. Pharmaceutical Biology 48:10, pages 1137-1148.
Read now
Read now
Robert R. Henry. (2008) Evolving concepts of type 2 diabetes management with oral medications: new approaches to an old disease. Current Medical Research and Opinion 24:8, pages 2189-2202.
Read now
Read now
Scott D Taylor & Bryan Hill. (2004) Recent advances in protein tyrosine phosphatase 1B inhibitors. Expert Opinion on Investigational Drugs 13:3, pages 199-214.
Read now
Read now
Articles from other publishers (186)
Abhik Paul, Arnab Sarkar, Tanmoy Banerjee, Avik Maji, Shrabanti Sarkar, Sourav Paul, Sanmoy Karmakar, Nilanjan Ghosh & Tapan Kumar Maity. (2023) Structural and molecular insights of protein tyrosine phosphatase 1B (PTP1B) and its inhibitors as anti-diabetic agents. Journal of Molecular Structure 1293, pages 136258.
Crossref
Crossref
Mélissa Matou, Patrick Merciris, Mayra Luz Sanchez-Villavicencio, Gaëtan Herbette, Remi Neviere, Pierre Haddad, Thérèse Marianne-Pepin & Sylvie Bercion. (2023) Polyphenolic compounds of Phyllanthus amarus Schum & Thonn. (1827) and diabetes-related activity of an aqueous extract as affected by in vitro gastrointestinal digestion. Journal of Ethnopharmacology 315, pages 116619.
Crossref
Crossref
Mark Andrian B. Macalalad & Arthur A. GonzalesIIIIII. (2023) In Silico Screening and Identification of Antidiabetic Inhibitors Sourced from Phytochemicals of Philippine Plants against Four Protein Targets of Diabetes (PTP1B, DPP-4, SGLT-2, and FBPase). Molecules 28:14, pages 5301.
Crossref
Crossref
Ji-Feng Zhao, Li-Hua Li, Xiao-Jing Guo, Hai-Xia Zhang, Lin-Lin Tang, Chuan-Hua Ding & Wen-Shan Liu. (2023) Identification of natural product inhibitors of PTP1B based on high-throughput virtual screening strategy: In silico, in vitro and in vivo studies. International Journal of Biological Macromolecules 243, pages 125292.
Crossref
Crossref
Olulope Olufemi Ajayi. 2023. Next‐Generation Algae. Next‐Generation Algae
223
250
.
Olulope Olufemi Ajayi. 2023. Next‐Generation Algae. Next‐Generation Algae
223
250
.
Fatma Haddad, Ghadeer Dokmak, Maryam Bader & Rafik Karaman. (2023) A Comprehensive Review on Weight Loss Associated with Anti-Diabetic Medications. Life 13:4, pages 1012.
Crossref
Crossref
Na Li, Xinyu Li, Meidi Deng, Feifei Zhu, Zian Wang, Ruilong Sheng, Wenhui Wu & Ruihua Guo. (2023) Isosteviol derivatives as protein tyrosine Phosphatase-1B inhibitors: Synthesis, biological evaluation and molecular docking. Bioorganic & Medicinal Chemistry 83, pages 117240.
Crossref
Crossref
Chuanliang Zhang, Xianmin Yang, Xinjia Meng, Lijuan Wu, Xiaochun Liu, Jiangming Gao, Shan Liu, Juan Wu, Dingmin Huang, Zhenwei Wang & Xianbin Su. (2023)
Discovery of Novel PTP1B Inhibitors with Once-Weekly Therapeutic Potential for Type 2 Diabetes: Design, Synthesis, and
In Vitro
and
In Vivo
Investigations of BimBH3 Peptide Analogues
. Journal of Medicinal Chemistry 66:4, pages 3030-3044.
Crossref
Crossref
Tathagata Pradhan, Ojasvi Gupta, Vivek Kumar, Sristi & Gita Chawla. (2022) A comprehensive review on the antidiabetic attributes of thiazolidine‐4‐ones: Synthetic strategies and structure–activity relationships. Archiv der Pharmazie 356:2.
Crossref
Crossref
Shivani Sharma, Ali Ebrahim & Daniel A. Keedy. (2023) Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B. Acta Crystallographica Section F Structural Biology Communications 79:1, pages 23-30.
Crossref
Crossref
Xue-Qing Qian, Guo-Bo Xu, Ling-Yan Liu, Tao Yang, Guo-Lin Zhang & Guo-You Li. (2023) Chaetonigrisins A–L, a group of 3-Indole-1,2-Propanediol derived alkaloids from Chaetomium nigricolor YT-2. Bioorganic Chemistry 130, pages 106201.
Crossref
Crossref
Amy Woodfield, Tatiana Gonzales, Erik Helmerhorst, Simon Laws, Philip Newsholme, Tenielle Porter & Giuseppe Verdile. (2022) Current Insights on the Use of Insulin and the Potential Use of Insulin Mimetics in Targeting Insulin Signalling in Alzheimer’s Disease. International Journal of Molecular Sciences 23:24, pages 15811.
Crossref
Crossref
Chul-Min Park, Bong-Hwa Jeong, Raj Bhesh Sharma, Hyun-Jung Kim, Dong-Wook Kim & Dong-Young Rhyu. (2022) Crateva unilocularis Buch-Ham leaf extract improves glucose metabolism via regulation of insulin secretion and sensitivity in vitro and in vivo. Applied Biological Chemistry 65:1.
Crossref
Crossref
Anika J. Friedman, Evan T. Liechty, Levi Kramer, Ankur Sarkar, Jerome M. Fox & Michael R. Shirts. (2022) Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid. The Journal of Physical Chemistry B 126:42, pages 8427-8438.
Crossref
Crossref
Md Yousof Ali, Gerald W. Zamponi, Su Hui Seong, Hyun Ah Jung & Jae Sue Choi. (2022) 6-Formyl Umbelliferone, a Furanocoumarin from Angelica decursiva L., Inhibits Key Diabetes-Related Enzymes and Advanced Glycation End-Product Formation. Molecules 27:17, pages 5720.
Crossref
Crossref
Tapan Behl, Amit Gupta, Aayush Sehgal, Ali Albarrati, Mohammed Albratty, Abdulkarim M. Meraya, Asim Najmi, Saurabh Bhatia & Simona Bungau. (2022) Exploring protein tyrosine phosphatases (PTP) and PTP-1B inhibitors in management of diabetes mellitus. Biomedicine & Pharmacotherapy 153, pages 113405.
Crossref
Crossref
Triana Espinosa-Jiménez, Oriol Busquets, Amanda Cano, Elena Sánchez-López, Ester Verdaguer, Antoni Parcerisas, Jordi Olloquequi, Carme Auladell, Jaume Folch, Walter Wahli, Manuel Vázquez-Carrera, Antoni Camins & Miren Ettcheto. (2022) Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations. Frontiers in Pharmacology 13.
Crossref
Crossref
Hanif Fadhlurrahman, Azka Khoirunnisa & Isman Kurniawan. (2022) QSAR Model for Prediction PTP1B Inhibitor as Anti-diabetes Mellitus using Simulated Annealing-Support Vector Machine. QSAR Model for Prediction PTP1B Inhibitor as Anti-diabetes Mellitus using Simulated Annealing-Support Vector Machine.
Rongxing Liu, Cécile Mathieu, Jérémy Berthelet, Wenchao Zhang, Jean-Marie Dupret & Fernando Rodrigues Lima. (2022) Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives. International Journal of Molecular Sciences 23:13, pages 7027.
Crossref
Crossref
Jasvinder Singh Bhatti, Abhishek Sehrawat, Jayapriya Mishra, Inderpal Singh Sidhu, Umashanker Navik, Naina Khullar, Shashank Kumar, Gurjit Kaur Bhatti & P. Hemachandra Reddy. (2022) Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives. Free Radical Biology and Medicine 184, pages 114-134.
Crossref
Crossref
Reham M. Elhassan, Xuben Hou & Hao Fang. (2021) Recent advances in the development of allosteric protein tyrosine phosphatase inhibitors for drug discovery. Medicinal Research Reviews 42:3, pages 1064-1110.
Crossref
Crossref
Reecha Madaan, Rajeev K. Singla, Suresh Kumar, Ankit Kumar Dubey, Dinesh Kumar, Pooja Sharma, Rajni Bala, Shailja Singla & Bairong Shen. (2022) Bergenin - A Biologically Active Scaffold: Nanotechnological Perspectives. Current Topics in Medicinal Chemistry 22:2, pages 132-149.
Crossref
Crossref
Yong-Mei Ren, Rui Zhang, Zheling Feng, Chang-Qiang Ke, Sheng Yao, Chunping Tang, Ligen Lin & Yang Ye. (2021)
Macrocephatriolides A and B: Two Guaianolide Trimers from
Ainsliaea macrocephala
as PTP1B Inhibitors and Insulin Sensitizers
. The Journal of Organic Chemistry 86:24, pages 17782-17789.
Crossref
Crossref
Kubra Akyol & Deryanur Kilic. (2021) Discovery of novel and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B): Virtual screening and molecular dynamic simulation. Computers in Biology and Medicine 139, pages 104959.
Crossref
Crossref
Ashraf Ahmed Qurtam, Hamza Mechchate, Imane Es-safi, Mohammed Al-zharani, Fahd A. Nasr, Omar M. Noman, Mohammed Aleissa, Hamada Imtara, Abdulmalik M. Aleissa, Mohamed Bouhrim & Ali S. Alqahtani. (2021) Citrus Flavanone Narirutin, In Vitro and In Silico Mechanistic Antidiabetic Potential. Pharmaceutics 13:11, pages 1818.
Crossref
Crossref
Hyun-Su Lee, Jooyoung Kim, Hyun Gyu Choi, Eun-Kyung Kim & Chang-Duk Jun. (2021) Licoricidin Abrogates T-Cell Activation by Modulating PTPN1 Activity and Attenuates Atopic Dermatitis In Vivo. Journal of Investigative Dermatology 141:10, pages 2490-2498.e6.
Crossref
Crossref
Azita Gorji, Pearlyn Jia Ying Toh, Hui Ting Ong, Yi-Chin Toh, Yusuke Toyama & Pakorn Kanchanawong. (2021) Enhancement of Endothelialization by Topographical Features Is Mediated by PTP1B-Dependent Endothelial Adherens Junctions Remodeling. ACS Biomaterials Science & Engineering 7:6, pages 2661-2675.
Crossref
Crossref
Chuanliang Zhang, Lijuan Wu, Xiaochun Liu, Jiangming Gao, Shan Liu, Juan Wu, Dingmin Huang, Zhenwei Wang & Xianbin Su. (2021) Discovery of Novel PTP1B Inhibitors Derived from the BH3 Domain of Proapoptotic Bcl-2 Proteins with Antidiabetic Potency. ACS Medicinal Chemistry Letters 12:6, pages 1017-1023.
Crossref
Crossref
Nannan Chen, Mu Qin, Qunlin Gong, Nan Xu, Yu Lin, Jiahong Wang & Pengxiang Zheng. (2021) Construction of mRNA Regulatory Networks Reveals the Key Genes in Atrial Fibrillation. Computational and Mathematical Methods in Medicine 2021, pages 1-10.
Crossref
Crossref
Prateek Sharma, Sukhbir Singh, Vinay Thakur, Neelam Sharma & Ajmer Singh Grewal. (2021) Novel and emerging therapeutic drug targets for management of type 2 Diabetes Mellitus. Obesity Medicine 23, pages 100329.
Crossref
Crossref
Md Yousof Ali, Susoma Jannat & M. Mizanur Rahman. (2021) Investigation of C-glycosylated apigenin and luteolin derivatives’ effects on protein tyrosine phosphatase 1B inhibition with molecular and cellular approaches. Computational Toxicology 17, pages 100141.
Crossref
Crossref
C. K. Hoang, V. T. H. Nguyen, H. T. H. Tran, C. H. Le, T. D. Nguyen, Q. H. Tran, H. M. Le & H. T. N. Tran. (2021) Isolation and Structure Determination of PTP1B Inhibitor from Streptomyces sp. Strain TD-X10. Applied Biochemistry and Microbiology 57:1, pages 65-73.
Crossref
Crossref
Dinh-Tuan Nguyen, Dao-Cuong To, Thi-Tuyen Tran, Manh-Hung Tran & Phi-Hung Nguyen. (2020) PTP1B and α-glucosidase inhibitors from Selaginella rolandi-principis and their glucose uptake stimulation. Journal of Natural Medicines 75:1, pages 186-193.
Crossref
Crossref
José Rivera-Chávez, Diego Coporo-Blancas & Jesús Morales-Jiménez. (2020) One-step partial synthesis of (±)-asperteretone B and related hPTP1B1–400 inhibitors from butyrolactone I. Bioorganic & Medicinal Chemistry 28:24, pages 115817.
Crossref
Crossref
Sisir Nandi & Mridula Saxena. (2020) Potential Inhibitors of Protein Tyrosine Phosphatase (PTP1B) Enzyme: Promising Target for Type-II Diabetes Mellitus. Current Topics in Medicinal Chemistry 20:29, pages 2692-2707.
Crossref
Crossref
D. Paderina, A. Boiko, I. Pozhidaev, E. Kornetova & S. Ivanova. (2020) P.182 Metabolic syndrome in patients with schizophrenia and the PTPN5 gene encoding the striatal-enriched protein tyrosine phosphatase. European Neuropsychopharmacology 40, pages S106-S107.
Crossref
Crossref
Yunshao Xu, Zheling Feng, Tian Zhang, Peng Lv, Jun Cao, Dan Li, Cheng Peng & Ligen Lin. (2020) Pimarane Diterpenoids from the Seeds of Caesalpinia minax as PTP1B Inhibitors and Insulin Sensitizers. Molecules 25:20, pages 4674.
Crossref
Crossref
Javier García‐Marín, Mercedes Griera, Patricia Sánchez‐Alonso, Bruno Di Geronimo, Francisco Mendicuti, Manuel Rodríguez‐Puyol, Ramón Alajarín, Beatriz Pascual‐Teresa, Juan J. Vaquero & Diego Rodríguez‐Puyol. (2020)
Pyrrolo[1,2‐
a
]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B
. ChemMedChem 15:19, pages 1788-1801.
Crossref
Crossref
Ganesan Senthil Kumar, Rebecca Page & Wolfgang Peti. (2020) The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib. PLOS ONE 15:10, pages e0240044.
Crossref
Crossref
Jian-Bo Yang, Fei Ye, Jin-Ying Tian, Yun-Fei Song, Hui-Yu Gao, Yue Liu, Qi Wang, Ying Wang, Shuang-Cheng Ma, Xian-Long Cheng & Feng Wei. (2020) Multiflorumisides H K, stilbene glucosides isolated from Polygonum multiflorum and their in vitro PTP1B inhibitory activities. Fitoterapia 146, pages 104703.
Crossref
Crossref
Manh Tuan Ha, Srijan Shrestha, Thu Huong Tran, Jeong Ah Kim, Mi Hee Woo, Jae Sue Choi & Byung Sun Min. (2020) Inhibition of PTP1B by farnesylated 2-arylbenzofurans isolated from Morus alba root bark: unraveling the mechanism of inhibition based on in vitro and in silico studies. Archives of Pharmacal Research 43:9, pages 961-975.
Crossref
Crossref
Bigyan Sharma, Liuxing Xie, Fen Yang, Wei Wang, Quanming Zhou, Menghua Xiang, Shizhe Zhou, Wanting Lv, Yan Jia, Laxman Pokhrel, Jun Shen, Qicai Xiao, Liqian Gao & Wenbin Deng. (2020) Recent advance on PTP1B inhibitors and their biomedical applications. European Journal of Medicinal Chemistry 199, pages 112376.
Crossref
Crossref
Brenda S. Jiménez-Arreola, Enrique Aguilar-Ramírez, Patricia Cano-Sánchez, Jesús Morales-Jiménez, Martín González-Andrade, José L. Medina-Franco & José Rivera-Chávez. (2020) Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B1-400: Insights into mechanistic kinetics from in vitro and in silico studies. Bioorganic Chemistry 101, pages 103893.
Crossref
Crossref
Bin Liu, Runjiang Song, Jun Xu, Pankaj Kumar Majhi, Xing Yang, Song Yang, Zhichao Jin & Yonggui Robin Chi. (2020) Access to Optically Enriched α-Aryloxycarboxylic Esters via Carbene-Catalyzed Dynamic Kinetic Resolution and Transesterification. Organic Letters 22:9, pages 3335-3338.
Crossref
Crossref
Ying Yang, Jin-Ying Tian, Fei Ye & Zhiyan Xiao. (2020) Identification of natural products as selective PTP1B inhibitors via virtual screening. Bioorganic Chemistry 98, pages 103706.
Crossref
Crossref
Manuel Rangel-Grimaldo, Martha L. Macías-Rubalcava, Martin González-Andrade, Huzefa Raja, Mario Figueroa & Rachel Mata. (2020)
α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors from
Malbranchea circinata
. Journal of Natural Products 83:3, pages 675-683.
Crossref
Crossref
Mi Hee Woo, Duc Hung Nguyen, Jae Sue Choi, Se Eun Park, Phuong Thien Thuong, Byung Sun Min & Duc Dat Le. (2020) Chemical constituents from the roots of Kadsura coccinea with their protein tyrosine phosphatase 1B and acetylcholinesterase inhibitory activities. Archives of Pharmacal Research 43:2, pages 204-213.
Crossref
Crossref
Robert A. Cerulli & Joshua A. Kritzer. (2020) Phosphotyrosine isosteres: past, present and future. Organic & Biomolecular Chemistry 18:4, pages 583-605.
Crossref
Crossref
Bailey A. Plaman, Wai Cheung Chan & Anthony C. Bishop. (2019) Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals. Scientific Reports 9:1.
Crossref
Crossref
Yong Zhao, Louise Kjaerulff, Kenneth T. Kongstad, Allison M. Heskes, Birger Lindberg Møller & Dan Staerk. (2019) 2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity. Phytochemistry 166, pages 112054.
Crossref
Crossref
Pranav K. Prabhakar & Ponnurengam M. Sivakumar. (2019) Protein Tyrosine Phosphatase 1B Inhibitors: A Novel Therapeutic Strategy for the Management of type 2 Diabetes Mellitus. Current Pharmaceutical Design 25:23, pages 2526-2539.
Crossref
Crossref
Taoda Shi, E. M. Kithsiri Wijeratne, Cristian Solano, Andrew J. Ambrose, Alison B. Ross, Charles Norwood, Charles K. Orido, Tigran Grigoryan, Joseph Tillotson, Minjin Kang, Gang Luo, Bradley M. Keegan, Wenhao Hu, Brian S. J. Blagg, Donna D. Zhang, A. A. Leslie Gunatilaka & Eli Chapman. (2019) An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol. Biochemistry 58:30, pages 3225-3231.
Crossref
Crossref
Hongyan Liu, Danwen Sun, Hang Du, Changji Zheng, Jingya Li, Huri Piao, Jia Li & Liangpeng Sun. (2019) Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents. European Journal of Medicinal Chemistry 172, pages 163-173.
Crossref
Crossref
Chao Li, Jiao Luo, Shuju Guo, Xiaoling Jia, Chuanlong Guo, Xiangqian Li, Qi Xu & Dayong Shi. (2019) Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2′,3,3′-Tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice. Molecular Pharmaceutics 16:5, pages 1839-1850.
Crossref
Crossref
Wenjie Xue, Jinlong Tian, Xiang Simon Wang, Jie Xia & Song Wu. (2019) Discovery of potent PTP1B inhibitors via structure-based drug design, synthesis and in vitro bioassay of Norathyriol derivatives. Bioorganic Chemistry 86, pages 224-234.
Crossref
Crossref
Sant Kumar Verma, Yatesh Sharad Yadav & Suresh Thareja. (2019) 2,4-Thiazolidinediones as PTP 1B Inhibitors: A Mini Review (2012-2018). Mini-Reviews in Medicinal Chemistry 19:7, pages 591-598.
Crossref
Crossref
James J DiNicolantonio, Mark McCarty & James OKeefe. (2019) Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance?. Open Heart 6:1, pages e000897.
Crossref
Crossref
Su Jin Yang, Pradeep Paudel, Srijan Shrestha, Su Hui Seong, Hyun Ah Jung & Jae Sue Choi. (2018) In vitro protein tyrosine phosphatase 1B inhibition and antioxidant property of different onion peel cultivars: A comparative study. Food Science & Nutrition 7:1, pages 205-215.
Crossref
Crossref
Shahira Ezzat, Mahitab Bishbishy, Solomon Habtemariam, Bahare Salehi, Mehdi Sharifi-Rad, Natália Martins & Javad Sharifi-Rad. (2018) Looking at Marine-Derived Bioactive Molecules as Upcoming Anti-Diabetic Agents: A Special Emphasis on PTP1B Inhibitors. Molecules 23:12, pages 3334.
Crossref
Crossref
Brennan Marsh-Armstrong, Jesse M. Fajnzylber, Samuel Korntner, Bailey A. Plaman & Anthony C. Bishop. (2018) The Allosteric Site on SHP2’s Protein Tyrosine Phosphatase Domain is Targetable with Druglike Small Molecules. ACS Omega 3:11, pages 15763-15770.
Crossref
Crossref
Yanhui Zhang & Yongli Du. (2018) The development of protein tyrosine phosphatase1B inhibitors defined by binding sites in crystalline complexes. Future Medicinal Chemistry 10:19, pages 2345-2367.
Crossref
Crossref
Yanbo Tang, Xiaolin Zhang, Zheng Chen, Wenwen Yin, Guanglei Nan, Jinying Tian, Fei Ye & Zhiyan Xiao. (2018) Novel benzamido derivatives as PTP1B inhibitors with anti-hyperglycemic and lipid-lowering efficacy. Acta Pharmaceutica Sinica B 8:6, pages 919-932.
Crossref
Crossref
Rita de Cássia Lemos Lima, Kenneth T. Kongstad, Lucília Kato, Marcos José das Silva, Henrik Franzyk & Dan Staerk. (2018) High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules 23:7, pages 1755.
Crossref
Crossref
Xi Chen, Qiang Gan, Changgen Feng, Xia Liu & Qian Zhang. (2018) Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy. Journal of Chemical Information and Modeling 58:4, pages 837-847.
Crossref
Crossref
Fangfang Wang & Bo Zhou. (2018) Toward the identification of a reliable 3D-QSAR model for the protein tyrosine phosphatase 1B inhibitors. Journal of Molecular Structure 1158, pages 75-87.
Crossref
Crossref
Ammu Prasanna Kumar, Minh N. Nguyen, Chandra Verma & Suryani Lukman. (2018) Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites. Proteins: Structure, Function, and Bioinformatics 86:3, pages 301-321.
Crossref
Crossref
Dao-Li Guo. (2018)
A New Tannin from Fruits of
Torreya Nucifera
with Protein Tyrosine Phosphatase 1B Inhibitory Activity
. Natural Product Communications 13:2, pages 1934578X1801300.
Crossref
Crossref
Carina Proença, Marisa Freitas, Daniela Ribeiro, Joana L.C. Sousa, Félix Carvalho, Artur M.S. Silva, Pedro A. Fernandes & Eduarda Fernandes. (2018) Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study. Food and Chemical Toxicology 111, pages 474-481.
Crossref
Crossref
Yongli Du, Yanhui Zhang, Hao Ling, Qunyi Li & Jingkang Shen. (2018) Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site. European Journal of Medicinal Chemistry 144, pages 692-700.
Crossref
Crossref
Md. Ali, Da Kim, Su Seong, Hyeung-Rak Kim, Hyun Jung & Jae Choi. (2017) α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium. Marine Drugs 15:12, pages 368.
Crossref
Crossref
Dmytro Kukhtar, Miquel Mulero, Raul Beltrán-Debón, Cristina Valls, Gerard Pujadas & Santiago Garcia-Vallve. 2017. Drug Selectivity. Drug Selectivity
397
432
.
Jia-Lin Li, Na Li, Shan-Shan Xing, Nan Zhang, Ban-Ban Li, Jian-Guang Chen, Jong-Seog Ahn & Long Cui. (2015) New neo-lignan from Acanthopanax senticosus with protein tyrosine phosphatase 1B inhibitory activity. Archives of Pharmacal Research 40:11, pages 1265-1270.
Crossref
Crossref
Şafak Özhan Kocakaya, Mehmet Karakaplan & Rosario Scopelliti. (2017) Synthesis and crystal structure of a chiral lactam and three amino alcohols as potential protein tyrosine phosphates 1B inhibitors. Tetrahedron: Asymmetry 28:10, pages 1342-1349.
Crossref
Crossref
Takafumi Shintani, Satoru Higashi, Ryoko Suzuki, Yasushi Takeuchi, Reina Ikaga, Tomomi Yamazaki, Kenta Kobayashi & Masaharu Noda. (2017) PTPRJ Inhibits Leptin Signaling, and Induction of PTPRJ in the Hypothalamus Is a Cause of the Development of Leptin Resistance. Scientific Reports 7:1.
Crossref
Crossref
Le Zhang, Ban-Ban Li, Hao-Ze Li, Xiao Meng, Xin Lin, Yi-Yu Jiang, Jong-Seog Ahn & Long Cui. (2017) Four new neolignans isolated from Eleutherococcus senticosus and their protein tyrosine phosphatase 1B inhibitory activity (PTP1B). Fitoterapia 121, pages 58-63.
Crossref
Crossref
Chi N. Nguyen, Binh T.D. Trinh, Toan B. Tran, Le-Thu T. Nguyen, Anna K. Jäger & Lien-Hoa D. Nguyen. (2017) Anti-diabetic xanthones from the bark of Garcinia xanthochymus. Bioorganic & Medicinal Chemistry Letters 27:15, pages 3301-3304.
Crossref
Crossref
Binh Trinh, Anna Jäger & Dan Staerk. (2017) High-Resolution Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Vietnamese Plants. Molecules 22:7, pages 1228.
Crossref
Crossref
V. N. Sorokoumov & A. O. Shpakov. (2017) Protein phosphotyrosine phosphatase 1B: Structure, function, role in the development of metabolic disorders and their correction by the enzyme inhibitors. Journal of Evolutionary Biochemistry and Physiology 53:4, pages 259-270.
Crossref
Crossref
Binh T.D. Trinh, Tam T.T. Quach, Dung N. Bui, Dan Staerk, Lien-Hoa D. Nguyen & Anna K. Jäger. (2017) Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity. Fitoterapia 118, pages 126-131.
Crossref
Crossref
Suzhen Dong, Yubing Lei, Shikun Jia, Lixin Gao, Jia Li, Tong Zhu, Shunying Liu & Wenhao Hu. (2017) Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction. Bioorganic & Medicinal Chemistry Letters 27:4, pages 1105-1108.
Crossref
Crossref
Shunying Liu, Jun Jiang, Jianghui Chen, Qinghua Wei, Wenfeng Yao, Fei Xia & Wenhao Hu. (2017)
A DFT calculation-inspired Rh(
i
)-catalyzed reaction via suppression of α-H shift in α-alkyldiazoacetates
. Chemical Science 8:6, pages 4312-4317.
Crossref
Crossref
Sujay Basu, Philip Prathipati, Sachin Thorat, Shariq Ansari, Meena Patel, Vaibhav Jain, Ramana R. Jinugu, Sanjay Niranjan, Siddhartha De & Satyanarayana Reddy. (2017) Rational design, synthesis, and structure–activity relationships of 5-amino-1H-pyrazole-4-carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors. Bioorganic & Medicinal Chemistry 25:1, pages 67-74.
Crossref
Crossref
Changcheng Jing, Ziyan Li, Kaili Jia, Chen Chen, Xiao Liu, Beibei Wang, Wenhao Hu, Jia Li, Tong Zhu & Suzhen Dong. (2017) Discovery of Bisindole as a Novel Scaffold for Protein Tyrosine Phosphatase 1B Inhibitors. Archiv der Pharmazie 350:1, pages e1600173.
Crossref
Crossref
Wei Zou. (2016) Type 2 Diabetes Mellitus and Protein-Tyrosine Phosphatase 1B1. Journal of Diabetes, Metabolic Disorders & Control 3:8.
Crossref
Crossref
Chu Wan-Loy & Phang Siew-Moi. (2016) Marine Algae as a Potential Source for Anti-Obesity Agents. Marine Drugs 14:12, pages 222.
Crossref
Crossref
Gyun Jee Song, Myungsu Jung, Jong-Heon Kim, Hana Park, Md Habibur Rahman, Sheng Zhang, Zhong-Yin Zhang, Dong Ho Park, Hyun Kook, In-Kyu Lee & Kyoungho Suk. (2016) A novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation. Journal of Neuroinflammation 13:1.
Crossref
Crossref
Eunae Kim, Cheolhee Kim, Yong Cheol Kang, Zhiguo Liu, Su-Nam Kim, Hyun Jung Kim, Min-ho Oak, Jung Hyun Shim, Seung Sik Cho, Seung Hoon Cheon & Goo Yoon. (2016) Molecular Modeling of Licochalcone E as Protein Tyrosine Phosphatase 1B Inhibitor. Bulletin of the Korean Chemical Society 37:12, pages 2102-2105.
Crossref
Crossref
Ge Meng, Meilin Zheng, Mei Wang, Jing Tong, Weijuan Ge, Jiehe Zhang, Aqun Zheng, Jingya Li, Lixin Gao & Jia Li. (2016) Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I. European Journal of Medicinal Chemistry 122, pages 756-769.
Crossref
Crossref
Md. Yousof Ali, Hee Jin Jung, Susoma Jannat, Hyun Ah Jung & Jae Sue Choi. (2016)
In Vitro Antidiabetic and Antioxidant Potential of the Ethanolic Extract of Skipjack Tuna (
K
atsuwonus Pelamis
) Heart
. Journal of Food Biochemistry 40:4, pages 583-592.
Crossref
Crossref
Muhammad Nasimullah Qureshi, Sodik Numonov, Ajigu Abudurexiti & Haji Akber Aisa. (2016) Phytochemical investigations and evaluation of antidiabetic potential of Prunus dulcis nuts. LWT - Food Science and Technology 66, pages 311-317.
Crossref
Crossref
Xiaoqian Hu, Ningping Tao, Xichang Wang, Jianbo Xiao & Mingfu Wang. (2016) Marine-derived bioactive compounds with anti-obesity effect: A review. Journal of Functional Foods 21, pages 372-387.
Crossref
Crossref
Pei-Jie Chen, Shuang-Peng Cai, Yang Yang, Wan-Xia Li, Cheng Huang, Xiao-Ming Meng & Jun Li. (2016) PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells. Toxicology and Applied Pharmacology 292, pages 8-18.
Crossref
Crossref
Alan R. Saltiel. (2016) New therapeutic approaches for the treatment of obesity. Science Translational Medicine 8:323.
Crossref
Crossref
Suresh Thareja, Sant K. Verma, Diksha Haksar, Tilak R. Bhardwaj & Manoj Kumar. (2016) Discovery of novel cinnamylidene-thiazolidinedione derivatives as PTP-1B inhibitors for the management of type 2 diabetes. RSC Advances 6:110, pages 108928-108940.
Crossref
Crossref
Rongjun He & Zhong-Yin Zhang. 2016. Protein Tyrosine Phosphatases in Cancer. Protein Tyrosine Phosphatases in Cancer
335
353
.
Pei-Jie Chen, Shuang-Peng Cai, Cheng Huang, Xiao-Ming Meng & Jun Li. (2015) Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases. Toxicology 337, pages 10-20.
Crossref
Crossref
Su-Yang Jeong, Phi-Hung Nguyen, Bing-Tian Zhao, Md Yousof Ali, Jae-Sue Choi, Byung-Sun Min & Mi-Hee Woo. (2015)
Chemical Constituents of
Euonymus alatus
(Thunb.) Sieb. and Their PTP1B and α-Glucosidase Inhibitory Activities
. Phytotherapy Research 29:10, pages 1540-1548.
Crossref
Crossref
Tran Quang, Nguyen Ngan, Chi-Su Yoon, Kwang-Ho Cho, Dae Kang, Ho Lee, Youn-Chul Kim & Hyuncheol Oh. (2015) Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata. Molecules 20:6, pages 11173-11183.
Crossref
Crossref
Jing Chen, Li-Xin Gao, Jing-Xu Gong, Cheng-Shi Jiang, Li-Gong Yao, Jing-Ya Li, Jia Li, Wei Xiao & Yue-Wei Guo. (2015) Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters 25:10, pages 2211-2216.
Crossref
Crossref
Phi-Hung Nguyen, Bing-Tian Zhao, Md Yousof Ali, Jae-Sue Choi, Dong-Young Rhyu, Byung-Sun Min & Mi-Hee Woo. (2015)
Insulin-Mimetic Selaginellins from
Selaginella tamariscina
with Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity
. Journal of Natural Products 78:1, pages 34-42.
Crossref
Crossref
Xuan Thi-Anh Nguyen & Ly Le. (2014) Suggestion of suitable animal models for in vivo studies of protein tyrosine phosphatase 1b (PTP1B) inhibitors using computational approaches. SpringerPlus 3:1.
Crossref
Crossref
Rong-jun He, Zhi-hong Yu, Ruo-yu Zhang & Zhong-yin Zhang. (2014) Protein tyrosine phosphatases as potential therapeutic targets. Acta Pharmacologica Sinica 35:10, pages 1227-1246.
Crossref
Crossref
Hanying Ding, Yan Zhang, Chen Xu, Dongxia Hou, Jing Li, Yujing Zhang, Wei Peng, Ke Zen, Chen-Yu Zhang & Xiaohong Jiang. (2014) Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance in mice through inhibition of PTP1B. Diabetologia 57:10, pages 2145-2154.
Crossref
Crossref
Md. Nurul Islam, Ishrat Jahan Ishita, Hyun Ah Jung & Jae Sue Choi. (2014) Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties. Food and Chemical Toxicology 69, pages 55-62.
Crossref
Crossref
Yuejin Zhang, Jin Wang & Hongbo Guo. (2014) Ultrasound-assisted extraction of bergenin from Astilbe chinensis. Genetic Resources and Crop Evolution 61:5, pages 893-899.
Crossref
Crossref
Shuai Li, Jingmiao Zhang, Shaoyong Lu, Wenkang Huang, Lv Geng, Qiancheng Shen & Jian Zhang. (2014) The Mechanism of Allosteric Inhibition of Protein Tyrosine Phosphatase 1B. PLoS ONE 9:5, pages e97668.
Crossref
Crossref
Qingchao Liu, Tiantian Guo, Dong Li, Fahui Li & Wenhong Li. (2014) Synthesis and evaluation of several oleanolic acid glycoconjugates as protein tyrosine phosphatase 1B inhibitors. European Journal of Medicinal Chemistry 79, pages 34-46.
Crossref
Crossref
Yan-Bo Tang, Jun-Zheng Liu, Shu-En Zhang, Xin Du, Feilin Nie, Jin-Ying Tian, Fei Ye, Kai Huang, Jin-Ping Hu, Yan Li & Zhiyan Xiao. (2014) 3-Phenylpropanoic Acid-Based Phosphotyrosine (pTyr) Mimetics: Hit Evolution to a Novel Orally Active Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitor. ChemMedChem 9:5, pages 918-921.
Crossref
Crossref
Haojing Song, Jin Wang, Rui Zhang, Xiaoyan Liu, Guiyan Yuan, Chunmin Wei, Benjie Wang & Ruichen Guo. (2014)
Identification and characterization of human UDP-glucuronosyltransferases responsible for the
in vitro
glucuronidation of bergenin
. Biomedical Chromatography 28:3, pages 348-353.
Crossref
Crossref
Jun-Zheng Liu, Shu-En Zhang, Feilin Nie, Ying Yang, Yan-Bo Tang, Wenwen Yin, Jin-Ying Tian, Fei Ye & Zhiyan Xiao. (2013) Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib. Bioorganic & Medicinal Chemistry Letters 23:23, pages 6217-6222.
Crossref
Crossref
Haojing Song, Jin Wang, Rui Zhang, Xiaoyan Liu, Guiyan Yuan, Chunmin Wei, Wenjing Zhao, Rong Li, Benjie Wang & Ruichen Guo. (2013)
In vivo
metabolism study of bergenin in rats by HPLC-QTOF mass spectrometry
. Biomedical Chromatography 27:11, pages 1398-1405.
Crossref
Crossref
Rhushikesh A. Kulkarni, Nadeem A. Vellore, Matthew R. Bliss, Stephanie M. Stanford, Matthew D. Falk, Nunzio Bottini, Riccardo Baron & Amy M. Barrios. (2013) Substrate Selection Influences Molecular Recognition in a Screen for Lymphoid Tyrosine Phosphatase Inhibitors. ChemBioChem 14:13, pages 1640-1647.
Crossref
Crossref
Diana N. Obanda & William T. Cefalu. (2013) Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells. The Journal of Nutritional Biochemistry 24:8, pages 1529-1537.
Crossref
Crossref
Sachin K. Majumdar & Silvio E. Inzucchi. (2013) Investigational anti-hyperglycemic agents: the future of type 2 diabetes therapy?. Endocrine 44:1, pages 47-58.
Crossref
Crossref
Wenjuan Xing & Ligang Chen. (2013) Micelle-mediated extraction and cloud point preconcentration of bergenin from Ardisia japonica. Separation and Purification Technology 110, pages 57-62.
Crossref
Crossref
Wei Cui, Yuan-Hua Cheng, Ling-Ling Geng, Den-Sheng Liang, Ting-Jun Hou & Ming-Juan Ji. (2013) Unraveling the Allosteric Inhibition Mechanism of PTP1B by Free Energy Calculation Based on Umbrella Sampling. Journal of Chemical Information and Modeling 53:5, pages 1157-1167.
Crossref
Crossref
Qing-Chao Liu, Tian-Tian Guo, Lei Zhang, Yue Yu, Peng Wang, Ju-Fang Yang & Ying-Xia Li. (2013) Synthesis and biological evaluation of oleanolic acid derivatives as PTP1B inhibitors. European Journal of Medicinal Chemistry 63, pages 511-522.
Crossref
Crossref
Wenying Ren, Yingmin Sun, Sarwat Cheema & Keyong Du. (2013) Interaction of Constitutive Photomorphogenesis 1 Protein with Protein-Tyrosine Phosphatase 1B Suppresses Protein-Tyrosine Phosphatase 1B Activity and Enhances Insulin Signaling. Journal of Biological Chemistry 288:15, pages 10902-10913.
Crossref
Crossref
Azis Saifudin, Shigetoshi Kadota & Yasuhiro Tezuka. (2012) Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum. Journal of Natural Medicines 67:2, pages 264-270.
Crossref
Crossref
Prashant Joshi, Girdhar Singh Deora, Vandana Rathore, Arun K. Rawat, A. K. Srivastava & Deepti Jain. (2012) Molecular modeling and synthesis of ZINC02765569 derivatives as protein tyrosine phosphatase 1B inhibitors: lead optimization study. Medicinal Chemistry Research 22:4, pages 1618-1623.
Crossref
Crossref
Ryszard Gryboś, Patrycja Paciorek, Janusz T. Szklarzewicz, Dariusz Matoga, Piotr Zabierowski & Grzegorz Kazek. (2013) Novel vanadyl complexes of acetoacetanilide: Synthesis, characterization and inhibition of proteintyrosine phosphatase. Polyhedron 49:1, pages 100-104.
Crossref
Crossref
Prashant Joshi, Girdhar Singh Deora, Vandana Rathore, Omprakash Tanwar, Arun K. Rawat, A. K. Srivastava & Deepti Jain. (2012) Identification of ZINC02765569: a potent inhibitor of PTP1B by vHTS. Medicinal Chemistry Research 22:1, pages 28-34.
Crossref
Crossref
Christopher J. Carbone, Hui Zheng, Sabyasachi Bhattacharya, John R. LewisAlexander M. ReiterPaula HenthornZhong-Yin ZhangDarren P. Baker, Radha Ukkiramapandian, Kendra K. Bence & Serge Y. Fuchs. (2012) Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies. Proceedings of the National Academy of Sciences 109:47, pages 19226-19231.
Crossref
Crossref
Alexander N. Shikov, Olga N. Pozharitskaya, Marina N. Makarova, Maria A. Kovaleva, Into Laakso, H.J. Damien Dorman, Raimo Hiltunen, Valery G. Makarov & Bertalan Galambosi. (2012) Effect of Bergenia crassifolia L. extracts on weight gain and feeding behavior of rats with high-caloric diet-induced obesity. Phytomedicine 19:14, pages 1250-1255.
Crossref
Crossref
Solomon Habtemariam & Raymond A. Cowley. (2012)
Antioxidant and Anti‐α‐glucosidase Compounds from the Rhizome of
Peltiphyllum peltatum
(Torr.) Engl
. Phytotherapy Research 26:11, pages 1656-1660.
Crossref
Crossref
Jinguo Wang, Bingya Liu, Xuehua Chen, Liping Su, Pei Wu, Jian Wu & Zhenggang Zhu. (2011) PTP1B expression contributes to gastric cancer progression. Medical Oncology 29:2, pages 948-956.
Crossref
Crossref
Mariagrazia Roselli, Giovanni Lentini & Solomon Habtemariam. (2012)
Phytochemical, Antioxidant and Anti-α-glucosidase Activity Evaluations of
Bergenia cordifolia
. Phytotherapy Research 26:6, pages 908-914.
Crossref
Crossref
Suresh Thareja, Saurabh Aggarwal, T. R. Bhardwaj & Manoj Kumar. (2010) Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus. Medicinal Research Reviews 32:3, pages 459-517.
Crossref
Crossref
Sujay Basu, Uppuleti Viplava Prasad, Dinesh A. Barawkar, Siddhartha De, Venkata P. Palle, Suraj Menon, Meena Patel, Sachin Thorat, Umesh P. Singh, Koushik Das Sarma, Yogesh Waman, Sanjay Niranjan, Vishal Pathade, Ashwani Gaur, Satyanarayana Reddy & Shariq Ansari. (2012) Discovery of novel and potent heterocyclic carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors. Bioorganic & Medicinal Chemistry Letters 22:8, pages 2843-2849.
Crossref
Crossref
Paul Slobbe, Eelco Ruijter & Romano V. A. Orru. (2012) Recent applications of multicomponent reactions in medicinal chemistry. MedChemComm 3:10, pages 1189.
Crossref
Crossref
Bhooshan Kafle, Nilkanth G. Aher, Deegendra Khadka, Hwangseo Park & Hyeongjin Cho. (2011) Isoxazol-5(4H)one Derivatives as PTP1B Inhibitors Showing an Anti-Obesity Effect. Chemistry - An Asian Journal 6:8, pages 2073-2079.
Crossref
Crossref
Anna A. SzypowskaBoudewijn M.T. Burgering. (2011) The Peroxide Dilemma: Opposing and Mediating Insulin Action. Antioxidants & Redox Signaling 15:1, pages 219-232.
Crossref
Crossref
Bart C. De JongheMatthew R. Hayes, Ryoichi BannoKarolina P. Skibicka, Derek J. ZimmerKerisha A. BowenTheresa M. Leichner, Amber L. Alhadeff, Scott E. Kanoski, Nicole E. Cyr, Eduardo A. Nillni, Harvey J. Grill & Kendra K. Bence. (2011) Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure. American Journal of Physiology-Endocrinology and Metabolism 300:6, pages E1002-E1011.
Crossref
Crossref
Medhanit Bahta, George T. Lountos, Beverly Dyas, Sung-Eun Kim, Robert G. Ulrich, David S. Waugh & Terrence R. BurkeJr.Jr.. (2011)
Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the
Yersinia pestis
Outer Protein H (YopH) Phosphatase
. Journal of Medicinal Chemistry 54:8, pages 2933-2943.
Crossref
Crossref
Junfeng Ma, Zhe Li, Shu Xing, Wan-Ting Tina Ho, Xueqi Fu & Zhizhuang Joe Zhao. (2011) Tea contains potent inhibitors of tyrosine phosphatase PTP1B. Biochemical and Biophysical Research Communications 407:1, pages 98-102.
Crossref
Crossref
Sucheta B. Kurundkar, Narsingh Sachan, Kisan M. Kodam, Vithal M. Kulkarni, Subhash L. Bodhankar & Vikram S. Ghole. (2011) Effect of a novel biphenyl compound, VMNS2e on ob/ob mice. European Journal of Pharmacology 650:1, pages 472-478.
Crossref
Crossref
Shan Qian, Haijiao Li, Yin Chen, Weiyu Zhang, Shengyong Yang & Yong Wu. (2010) Synthesis and Biological Evaluation of Oleanolic Acid Derivatives As Inhibitors of Protein Tyrosine Phosphatase 1B. Journal of Natural Products 73:11, pages 1743-1750.
Crossref
Crossref
Bharat Raj Bhattarai, Bhooshan Kafle, Ji-Sun Hwang, Seung Wook Ham, Keun-Hyeung Lee, Hwangseo Park, Inn-Oc Han & Hyeongjin Cho. (2010) Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators. Bioorganic & Medicinal Chemistry Letters 20:22, pages 6758-6763.
Crossref
Crossref
Renate R. Baumgartner, Dirk Steinmann, Elke H. Heiss, Atanas G. Atanasov, Markus Ganzera, Hermann Stuppner & Verena M. Dirsch. (2010)
Bioactivity-Guided Isolation of 1,2,3,4,6-Penta-
O
-galloyl-
d
-glucopyranose from
Paeonia lactiflora
Roots As a PTP1B Inhibitor
. Journal of Natural Products 73:9, pages 1578-1581.
Crossref
Crossref
Clifford J. Bailey. 2010. Textbook of Diabetes. Textbook of Diabetes
1017
1044
.
Zandra E. Walton & Anthony C. Bishop. (2010) Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activity. Bioorganic & Medicinal Chemistry 18:14, pages 4884-4891.
Crossref
Crossref
Jian-Mei Li, Yu-Cheng Li, Ling-Dong Kong & Qing-Hua Hu. (2010) Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats. Hepatology 51:5, pages 1555-1566.
Crossref
Crossref
Raju V.S. Rajala, Masaki Tanito, Benjamin G. Neel & Ammaji Rajala. (2010) Enhanced Retinal Insulin Receptor-activated Neuroprotective Survival Signal in Mice Lacking the Protein-tyrosine Phosphatase-1B Gene. Journal of Biological Chemistry 285:12, pages 8894-8904.
Crossref
Crossref
Deju Ye, Yu Zhang, Fei Wang, Mingfang Zheng, Xu Zhang, Xiaomin Luo, Xu Shen, Hualiang Jiang & Hong Liu. (2010) Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity. Bioorganic & Medicinal Chemistry 18:5, pages 1773-1782.
Crossref
Crossref
Bharat Raj Bhattarai, Jeong-Hyeon Ko, Suja Shrestha, Bhooshan Kafle, Heeyeong Cho, Ju-Hee Kang & Hyeongjin Cho. (2010) Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32. Bioorganic & Medicinal Chemistry Letters 20:3, pages 1075-1077.
Crossref
Crossref
Suresh Thareja, Ganesh Rajendra Kokil, Saurabh Aggarwal, Tilak Raj Bhardwaj & Manoj Kumar. (2010) Sulphonamides as Inhibitors of Protein Tyrosine Phosphatase 1B: A Three-Dimensional Quantitative Structure-Activity Relationship Study Using Self-Organizing Molecular Field Analysis Approach. Chemical and Pharmaceutical Bulletin 58:4, pages 526-532.
Crossref
Crossref
Caixia Yuan, Liping Lu, Xiaoli Gao, Yanbo Wu, Maolin Guo, Ying Li, Xueqi Fu & Miaoli Zhu. (2009) Ternary oxovanadium(IV) complexes of ONO-donor Schiff base and polypyridyl derivatives as protein tyrosine phosphatase inhibitors: synthesis, characterization, and biological activities. JBIC Journal of Biological Inorganic Chemistry 14:6, pages 841-851.
Crossref
Crossref
Fateh V. Singh, Amrita Parihar, Sumit Chaurasia, Amar B. Singh, Salil P. Singh, Akhilesh K. Tamrakar, Arvind K. Srivastava & Atul Goel. (2009) 5,6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agents. Bioorganic & Medicinal Chemistry Letters 19:8, pages 2158-2161.
Crossref
Crossref
John J. MieyalMolly M. GalloglySuparna QanungoElizabeth A. SabensMelissa D. Shelton. (2008)
Molecular Mechanisms and Clinical Implications of Reversible Protein
S
-Glutathionylation
. Antioxidants & Redox Signaling 10:11, pages 1941-1988.
Crossref
Crossref
Zhao-Kui Wan, Jinbo Lee, Rajeev Hotchandani, Alessandro Moretto, Eva Binnun, Douglas P. Wilson, Steve J. Kirincich, Bruce C. Follows, Manus Ipek, Weixin Xu, Diane Joseph-McCarthy, Yan-Ling Zhang, May Tam, David V. Erbe, James F. Tobin, Wei Li, Steve Y. Tam, Tarek S. Mansour & Junjun Wu. (2008) Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24. ChemMedChem 3:10, pages 1525-1529.
Crossref
Crossref
Qing Ling, Yue Huang, Yueyang Zhou, Zhengliang Cai, Bing Xiong, Yahui Zhang, Lanping Ma, Xin Wang, Xin Li, Jia Li & Jingkang Shen. (2008) Illudalic acid as a potential LAR inhibitor: Synthesis, SAR, and preliminary studies on the mechanism of action. Bioorganic & Medicinal Chemistry 16:15, pages 7399-7409.
Crossref
Crossref
Andrea Nören‐Müller, Wolfram Wilk, Krishna Saxena, Harald Schwalbe, Markus Kaiser & Herbert Waldmann. (2008)
Discovery of a New Class of Inhibitors of
Mycobacterium tuberculosis
Protein Tyrosine Phosphatase B by Biology‐Oriented Synthesis
. Angewandte Chemie International Edition 47:32, pages 5973-5977.
Crossref
Crossref
Andrea Nören-Müller, Wolfram Wilk, Krishna Saxena, Harald Schwalbe, Markus Kaiser & Herbert Waldmann. (2008)
Entwicklung einer neuen Klasse von Inhibitoren der Proteintyrosinphosphatase-B aus
Mycobacterium tuberculosis
durch Biologie-orientierte Synthese (BIOS)
. Angewandte Chemie 120:32, pages 6061-6066.
Crossref
Crossref
Hung-Yun Lin, I-Chen Yu, Ruey-Shen Wang, Yei-Tsung Chen, Ning-Chun Liu, Saleh Altuwaijri, Cheng-Lung Hsu, Wen-Lung Ma, Jenny Jokinen, Janet D. Sparks, Shuyuan Yeh & Chawnshang Chang. (2008) Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology 47:6, pages 1924-1935.
Crossref
Crossref
Christopher P. Holmes, Xianfeng Li, Yijun Pan, Caiding Xu, Ashok Bhandari, Claire M. Moody, Joy A. Miguel, Steven W. Ferla, M. Nuria De Francisco, Brian T. Frederick, Siqun Zhou, Natalie Macher, Larry Jang, Jennifer D. Irvine & J. Russell Grove. (2008) PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold. Bioorganic & Medicinal Chemistry Letters 18:8, pages 2719-2724.
Crossref
Crossref
Jonathan Chernoff. (2008) Ptp1b. AfCS-Nature Molecule Pages.
Crossref
Crossref
David R. Adams, Achamma Abraham, Jun Asano, Catherine Breslin, Colin A.J. Dick, Ulrich Ixkes, Blair F. Johnston, Derek Johnston, Justin Kewnay, Simon P. Mackay, Simon J. MacKenzie, Morag McFarlane, Lee Mitchell, Daniel Spinks & Yasuo Takano. (2007) 2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: A new class of protein tyrosine phosphatase 1B inhibitors. Bioorganic & Medicinal Chemistry Letters 17:23, pages 6579-6583.
Crossref
Crossref
Zhe Shi, Sartaj Tabassum, Wei Jiang, Jiahai Zhang, Suvigya Mathur, Jihui Wu & Yunyu Shi. (2007) Identification of a Potent Inhibitor of Human Dual-Specific Phosphatase, VHR, from Computer-Aided and NMR-Based Screening to Cellular Effects. ChemBioChem 8:17, pages 2092-2099.
Crossref
Crossref
Shudong Zhu, Jeffrey D. Bjorge & Donald J. Fujita. (2007) PTP1B Contributes to the Oncogenic Properties of Colon Cancer Cells through Src Activation. Cancer Research 67:21, pages 10129-10137.
Crossref
Crossref
Makoto Hiromura, Akihiro Nakayama, Yusuke Adachi, Miyuki Doi & Hiromu Sakurai. (2007) Action mechanism of bis(allixinato)oxovanadium(IV) as a novel potent insulin-mimetic complex: regulation of GLUT4 translocation and FoxO1 transcription factor. JBIC Journal of Biological Inorganic Chemistry 12:8, pages 1275-1287.
Crossref
Crossref
Bharat Raj Bhattarai, Suja Shrestha, Seung Wook Ham, Kwang Rok Kim, Hyae Gyeong Cheon, Keun-Hyeung Lee & Hyeongjin Cho. (2007) 2-O-Carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity. Bioorganic & Medicinal Chemistry Letters 17:19, pages 5357-5360.
Crossref
Crossref
Anthony C. Bishop, Xin-Yu Zhang & Anna Mari Lone. (2007) Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations. Methods 42:3, pages 278-288.
Crossref
Crossref
Shojiro Inada, Yukio Ikeda, Tadashi Suehiro, Hiroshi Takata, Fumiaki Osaki, Kaoru Arii, Yoshitaka Kumon & Kozo Hashimoto. (2007) Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes. Molecular and Cellular Endocrinology 271:1-2, pages 64-70.
Crossref
Crossref
Suja Shrestha, Bharat Raj Bhattarai, Heeyeong Cho, Joong-Kwon Choi & Hyeongjin Cho. (2007) PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IκB kinase β (IKK-β). Bioorganic & Medicinal Chemistry Letters 17:10, pages 2728-2730.
Crossref
Crossref
Clifford J Bailey. (2016) Treating insulin resistance: future prospects. Diabetes and Vascular Disease Research 4:1, pages 20-31.
Crossref
Crossref
Manish Dixit, Brajendra K. Tripathi, Akhilesh K. Tamrakar, Arvind K. Srivastava, Brijesh Kumar & Atul Goel. (2007) Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors. Bioorganic & Medicinal Chemistry 15:2, pages 727-734.
Crossref
Crossref
L. Schmeltz & B. Metzger. 2007. Comprehensive Medicinal Chemistry II. Comprehensive Medicinal Chemistry II
417
458
.
Balázs Szöőr, Jude Wilson, Helen McElhinney, Lydia Tabernero & Keith R. Matthews. (2006)
Protein tyrosine phosphatase
Tb
PTP1: a molecular switch controlling life cycle differentiation in trypanosomes
. The Journal of Cell Biology 175:2, pages 293-303.
Crossref
Crossref
Christopher. A. McCulloch, Gregory P. Downey & Hani El-Gabalawy. (2006) Signalling platforms that modulate the inflammatory response: new targets for drug development. Nature Reviews Drug Discovery 5:10, pages 864-876.
Crossref
Crossref
Sung Yun Cho, Ji Yoen Baek, Sang Sub Han, Seung Kyu Kang, Jae Du Ha, Jin Hee Ahn, Jae Don Lee, Kwang Rok Kim, Hyae Gyeong Cheon, Sang Dal Rhee, Sung Don Yang, Gyu Hwan Yon, Chwang Siek Pak & Joong-Kwon Choi. (2006) PTP-1B inhibitors: Cyclopenta[d][1,2]-oxazine derivatives. Bioorganic & Medicinal Chemistry Letters 16:3, pages 499-502.
Crossref
Crossref
Gui-xia LIU, Jin-zhi TAN, Chun-ying NIU, Jian-hua SHEN, Xiao-min LUO, Xu SHEN, Kai-xian CHEN & Hua-liang JIANG. (2006) Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor1. Acta Pharmacologica Sinica 27:1, pages 100-110.
Crossref
Crossref
Hyangkyu Lee, Laiping Xie, Yong Luo, Seung-Yub Lee, David S. Lawrence, Xiao Bo Wang, Federica Sotgia, Michael P. Lisanti & Zhong-Yin Zhang. (2005) Identification of Phosphocaveolin-1 as a Novel Protein Tyrosine Phosphatase 1B Substrate. Biochemistry 45:1, pages 234-240.
Crossref
Crossref
George Karanastasis & Christos S. Mantzoros. 2006. Obesity and Diabetes. Obesity and Diabetes
3
13
.
David S. Lawrence. 2006. Understanding Biology Using Peptides. Understanding Biology Using Peptides
320
324
.
Zhong-Yin Zhang. (2005) Functional studies of protein tyrosine phosphatases with chemical approaches. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1754:1-2, pages 100-107.
Crossref
Crossref
David S. Lawrence. (2005) Signaling protein inhibitors via the combinatorial modification of peptide scaffolds. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1754:1-2, pages 50-57.
Crossref
Crossref
Kimberly A. Watson, Evangelia D. Chrysina, Katerina E. Tsitsanou, Spyros E. Zographos, Georgios Archontis, George W.J. Fleet & Nikos G. Oikonomakos. (2005) Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins: Structure, Function, and Bioinformatics 61:4, pages 966-983.
Crossref
Crossref
Seung-Yub Lee, Fubo Liang, Xiao-Ling Guo, Laiping Xie, Sean M. Cahill, Michael Blumenstein, Heyi Yang, David S. Lawrence & Zhong-Yin Zhang. (2005) Design, Construction, and Intracellular Activation of an Intramolecularly Self-Silenced Signal Transduction Inhibitor. Angewandte Chemie International Edition 44:27, pages 4242-4244.
Crossref
Crossref
Seung-Yub Lee, Fubo Liang, Xiao-Ling Guo, Laiping Xie, Sean M. Cahill, Michael Blumenstein, Heyi Yang, David S. Lawrence & Zhong-Yin Zhang. (2005) Design, Construction, and Intracellular Activation of an Intramolecularly Self-Silenced Signal Transduction Inhibitor. Angewandte Chemie 117:27, pages 4314-4316.
Crossref
Crossref
Fubo Liang, Seung-Yub Lee, Jiao Liang, David S. Lawrence & Zhong-Yin Zhang. (2005) The Role of Protein-tyrosine Phosphatase 1B in Integrin Signaling. Journal of Biological Chemistry 280:26, pages 24857-24863.
Crossref
Crossref
Kyung-Joo Cho, Hadi Moini, An-Sik Chung & Lester Packer. 2005. Nutrigenomics. Nutrigenomics
283
300
.
N. P. H. Møller, H. S. Andersen, C. B. Jeppesen & L. F. Iversen. 2005. Inhibitors of Protein Kinases and Protein Phosphates. Inhibitors of Protein Kinases and Protein Phosphates
215
262
.
Hongyu Zhao, Gang Liu, Zhili Xin, Michael D. Serby, Zhonghua Pei, Bruce G. Szczepankiewicz, Philip J. Hajduk, Cele Abad-Zapatero, Charles W. Hutchins, Thomas H. Lubben, Stephen J. Ballaron, Deanna L. Haasch, Wiweka Kaszubska, Cristina M. Rondinone, James M. Trevillyan & Michael R. Jirousek. (2004) Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors. Bioorganic & Medicinal Chemistry Letters 14:22, pages 5543-5546.
Crossref
Crossref
Jacqueline Montalibet & Brian P. Kennedy. (2004) Using yeast to screen for inhibitors of protein tyrosine phosphatase 1B. Biochemical Pharmacology 68:9, pages 1807-1814.
Crossref
Crossref
Ida Katrine Lund, Henrik Sune Andersen, Lars Fogh Iversen, Ole Hvilsted Olsen, Karin Bach Møller, Anja Kallesøe Pedersen, Yu Ge, Daniel D. Holsworth, Michael J. Newman, Frank U. Axe & Niels Peter Hundahl Møller. (2004) Structure-based Design of Selective and Potent Inhibitors of Protein-tyrosine Phosphatase β. Journal of Biological Chemistry 279:23, pages 24226-24235.
Crossref
Crossref