Citations (44)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Jee Sun Min, Doyun Kim, Jung Bae Park, Hyunjin Heo, Soo Hyeon Bae, Jae Hong Seo, Euichaul Oh & Soo Kyung Bae. (2016) Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans. Drug Design, Development and Therapy 10, pages 2959-2972.
Read now
Read now
Giorgio Gentile, Daniela Mastroluca, Piero Ruggenenti & Giuseppe Remuzzi. (2014) Novel effective drugs for diabetic kidney disease? or not?. Expert Opinion on Emerging Drugs 19:4, pages 571-601.
Read now
Read now
Hisanori Horiuchi. (2006) Recent advance in antiplatelet therapy: The mechanisms, evidence and approach to the problems. Annals of Medicine 38:3, pages 162-172.
Read now
Read now
Articles from other publishers (41)
Ahram Han, Taeseung Lee, Joongyub Lee, Suk-Won Song, Sang-Su Lee, In Mok Jung, Jin Mo Kang, Jun Gyo Gwon, Woo-Sung Yun, Yong-Pil Cho, Hyunmin Ko, Yang-Jin Park & Seung-Kee Min. (2023) A multicenter, randomized, open-labelled, non-inferiority trial of sustained-release sarpogrelate versus clopidogrel after femoropopliteal artery intervention. Scientific Reports 13:1.
Crossref
Crossref
Juan Francisco Fernández-González, José Ángel García-Pedraza, Ana Marín-Quílez, José María Bastida, María Luisa Martín, Asunción Morán & Mónica García-Domingo. (2022) Effect of sarpogrelate treatment on 5-HT modulation of vascular sympathetic innervation and platelet activity in diabetic rats. Biomedicine & Pharmacotherapy 153, pages 113276.
Crossref
Crossref
Takashi Owaki, Kenya Kamimura, Masayoshi Ko, Itsuo Nagayama, Takuro Nagoya, Osamu Shibata, Chiyumi Oda, Shinichi Morita, Atsushi Kimura, Takeki Sato, Toru Setsu, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo & Shuji Terai. (2022) Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A. Disease Models & Mechanisms 15:7.
Crossref
Crossref
Chang Su, Yongzheng Lu, Zeyu Wang, Jiacheng Guo, Yachen Hou, Xiaofang Wang, Zhen Qin, Jiamin Gao, Zhaowei Sun, Yichen Dai, Yu Liu, Guozhen Liu, Xunde Xian, Xiaolin Cui, Jinying Zhang & Junnan Tang. (2022) Atherosclerosis: The Involvement of Immunity, Cytokines and Cells in Pathogenesis, and Potential Novel Therapeutics. Aging and disease, pages 0.
Crossref
Crossref
Zeinab Vahidinia, Mohammad Taghi Joghataei, Cordian Beyer, Mohammad Karimian & Abolfazl Azami Tameh. (2021) G-Protein-Coupled Receptors and Ischemic Stroke: a Focus on Molecular Function and Therapeutic Potential. Molecular Neurobiology 58:9, pages 4588-4614.
Crossref
Crossref
Y.H. Ding, B. Liu, J.F. Lou, J.X. Sun, M. Wu, X.X. Zhu, G.L. Chen, H. Zhang, X.J. Li, H. Chen, C.J. Liu, Z.W. Shen & C.Y. Li. (2019) Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4-Way Replicate Crossover Investigation by a Reference-Scaled Average Bioequivalence Approach. Clinical Pharmacology in Drug Development 8:6, pages 713-720.
Crossref
Crossref
Yunxin Lu, Jiangmiao Li, Jiayi Xie, Qingliang Yu & Liang Liao. (2019) Effects of sarpogrelate hydrochloride on peripheral arterial disease. Medicine 98:46, pages e17266.
Crossref
Crossref
Laurent Monassier & Luc Maroteaux. 2019. Serotonin. Serotonin
203
238
.
Annika Gocht, Jörg H.W. Distler, Bernd Spriewald, Martina Ramsperger-Gleixner, Michael Weyand, Stephan M. Ensminger & Christian Heim. (2018) Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts. Transplant Immunology 49, pages 43-53.
Crossref
Crossref
Hun Jun, Hyo-Jung Lee, Beom-Soo Shin & Chun-Woong Park. (2017) Preparation and in vivo characterization of dual release tablet containing sarpogrelate hydrochloride. Journal of Pharmaceutical Investigation 48:3, pages 363-372.
Crossref
Crossref
José Ángel García-PedrazaOswaldo Hernández-AbreuMónica GarcíaAsunción MoránCarlos M. Villalón. (2018)
Chronic 5-HT
2
receptor blockade unmasks the role of 5-HT
1F
receptors in the inhibition of rat cardioaccelerator sympathetic outflow
. Canadian Journal of Physiology and Pharmacology 96:4, pages 328-336.
Crossref
Crossref
Sanghyun Ahn, Joongyub Lee, Seung-Kee Min, Jongwon Ha, Sang-il Min, Song-Yi Kim, Min-Ji Cho & Sungsin Cho. (2017) SAFE (Sarpogrelate Anplone in Femoro-popliteal artery intervention Efficacy) study: study protocol for a randomized controlled trial. Trials 18:1.
Crossref
Crossref
José Ángel García-Pedraza, Mónica García, María Luisa Martín, Nélida Eleno & Asunción Morán. (2017) Chronic Sarpogrelate Treatment Reveals 5-HT7 Receptor in the Serotonergic Inhibition of the Rat Vagal Bradycardia. Journal of Cardiovascular Pharmacology 69:1, pages 13-22.
Crossref
Crossref
Hangyeore Lee, Sehyun Chae, Jisook Park, Jingi Bae, Eun-Bi Go, Su-Jin Kim, Hokeun Kim, Daehee Hwang, Sang-Won Lee & Soo-Youn Lee. (2016) Comprehensive Proteome Profiling of Platelet Identified a Protein Profile Predictive of Responses to An Antiplatelet Agent Sarpogrelate. Molecular & Cellular Proteomics 15:11, pages 3461-3472.
Crossref
Crossref
José-Ángel García-Pedraza, Pedro Ferreira-Santos, Rubén Aparicio, María-José Montero & Asunción Morán. (2016) Blocking 5-HT2 receptor restores cardiovascular disorders in type 1 experimental diabetes. Scientific Reports 6:1.
Crossref
Crossref
Dong-hyun Kim, Bo-hyun Choi, Sae-Kwang Ku, Jeong-hyeon Park, Euichaul Oh & Mi-Kyoung Kwak. (2016) Beneficial Effects of Sarpogrelate and Rosuvastatin in High Fat Diet/Streptozotocin-Induced Nephropathy in Mice. PLOS ONE 11:4, pages e0153965.
Crossref
Crossref
J.A. García-Pedraza, M. García, M.L. Martín, A. Rodríguez-Barbero & A. Morán. (2016) 5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature. Vascular Pharmacology 79, pages 51-59.
Crossref
Crossref
Jun Saito, Eiji Suzuki, Yoshitaka Tajima, Kazuhisa Takami, Yukio Horikawa & Jun Takeda. (2016) Increased plasma serotonin metabolite 5-hydroxyindole acetic acid concentrations are associated with impaired systolic and late diastolic forward flows during cardiac cycle and elevated resistive index at popliteal artery and renal insufficiency in type 2 diabetic patients with microalbuminuria. Endocrine Journal 63:1, pages 69-76.
Crossref
Crossref
Jung Bae Park, Soo Kyung Bae, Soo Hyeon Bae & Euichaul Oh. (2015) Simultaneous determination of sarpogrelate and its active metabolite in human plasma by liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. Journal of Separation Science 38:1, pages 42-49.
Crossref
Crossref
Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim & Soo Kyung Bae. (2014) Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes. Drug Metabolism and Disposition 42:1, pages 33-39.
Crossref
Crossref
Susumu Watada, Hirohisa Harada, Kentaro Matsubara, Hideaki Obara, Kenji Matsumoto, Nobutoshi Ando & Yuko Kitagawa. (2013) Effect of sarpogrelate hydrochloride, a 5-hydroxytryptamine2 receptor antagonist, on allograft arteriosclerosis after aortic transplantation in rats. Transplant Immunology 29:1-4, pages 162-166.
Crossref
Crossref
Il Soon Jeong, Jae-Hyeong Park, Seon Ah Jin, Jun Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong & In-Whan Seong. (2012) Oral sarpogrelate can improve endothelial dysfunction as effectively as oral cilostazol, with fewer headaches, in active young male smokers. Heart and Vessels 28:5, pages 578-582.
Crossref
Crossref
Jin Ah Jung, Jung-Ryul Kim, Tae-Eun Kim, Soo-Youn Lee, Wooseong Huh, Jae Won Lee, Hun Jun & Jae-Wook Ko. (2013) Effect of Food on the Pharmacokinetic Properties of the Oral Sarpogrelate Hydrochloride Controlled-Release Tablet in Healthy Male Korean Subjects. Clinical Therapeutics 35:7, pages 1038-1044.
Crossref
Crossref
Dong Chan Kim, Dae Won Jun, Young Il Kwon, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Byung Chul Yoon, Ho Soon Choi & Eun Kyung Kim. (2013)
5‐
HT
2A
receptor antagonists inhibit hepatic stellate cell activation and facilitate apoptosis
. Liver International 33:4, pages 535-543.
Crossref
Crossref
Ying Su, Nan Mao, Min Li, Xia Dong, Fan-Zhen Lin, Ying Xu & Yan-Bo Li. (2012) Sarpogrelate inhibits the expression of ICAM-1 and monocyte–endothelial adhesion induced by high glucose in human endothelial cells. Molecular and Cellular Biochemistry 373:1-2, pages 195-199.
Crossref
Crossref
Fumio Liu, Hiroshi Wada, Kenichi Sakakura, Taishi Hirahara, Kenshiro Arao, Yousuke Taniguchi, Daisuke Ono, Junya Ako & Shin-ichi Momomura. (2012) Refractory variant angina with a seasonal trend treated with sarpogrelate hydrochloride. Journal of Cardiology Cases 6:6, pages e176-e178.
Crossref
Crossref
B. Restrepo, M. García, C. López, M.L. Martín, L. San Román & A. Morán. (2012) The Cyclooxygenase and Nitric Oxide Synthesis/Pathways Mediate the Inhibitory Serotonergic Response to the Pressor Effect Elicited by Sympathetic Stimulation in Long-Term Diabetic Pithed Rats. Pharmacology 90:3-4, pages 169-176.
Crossref
Crossref
Yan-Ming Sun, Ying Su, Hong-Bo Jin, Jia Li & Sheng Bi. (2011) Sarpogrelate protects against high glucose-induced endothelial dysfunction and oxidative stress. International Journal of Cardiology 147:3, pages 383-387.
Crossref
Crossref
Seong Yup KimSang Hyun AhnSang Il MinSi Hwa KimYu Jin JeongSeung Kee MinSang Joon KimJongwon Ha. (2011) Effects of Antiplatelet Agents on the Graft Survival in Murine Cardiac and Skin Transplantation Model. The Journal of the Korean Society for Transplantation 25:1, pages 31.
Crossref
Crossref
Chao Zhang, Lu Wang, Yan Yang, Yantong Sun, Jie Zhang, Guoqing Li & Jingkai Gu. (2010) Validated LC–MS/MS method for the determination of sarpogrelate in human plasma: Application to a pharmacokinetic and bioequivalence study in Chinese volunteers. Journal of Pharmaceutical and Biomedical Analysis 53:3, pages 546-551.
Crossref
Crossref
Asunción Morán, Beatriz Restrepo, Ana Vega. Ortiz de Urbina, Mónica García, Maria Luisa Martín & Luis San Román. (2010) Pharmacological profile of 5-hydroxytryptamine-induced inhibition on the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats. European Journal of Pharmacology 643:1, pages 70-77.
Crossref
Crossref
K. PRZYKLENK, A.L. FRELINGERIIIIII, M.D. LINDEN, P. WHITTAKER, Y. LI, M.R. BARNARD, J. ADAMS, M. MORGAN, H. AL‐SHAMMA & A.D. MICHELSON. (2010) Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis. Journal of Thrombosis and Haemostasis 8:2, pages 331-340.
Crossref
Crossref
Santosh K. Sanganalmath, Andrea P. Babick, Judit Barta, Hideo Kumamoto, Nobuakiya Takeda & Naranjan S. Dhalla. (2008) Antiplatelet therapy attenuates subcellular remodelling in congestive heart failure. Journal of Cellular and Molecular Medicine 12:5a, pages 1728-1738.
Crossref
Crossref
Santosh K. SanganalmathJudit BartaNobuakira TakedaHideo KumamotoNaranjan S. Dhalla. (2008) Antiplatelet therapy mitigates cardiac remodeling and dysfunction in congestive heart failure due to myocardial infarctionThis article is one of a selection of papers published in the special issue Bridging the Gap: Where Progress in Cardiovascular and Neurophysiologic Research Meet.. Canadian Journal of Physiology and Pharmacology 86:4, pages 180-189.
Crossref
Crossref
Susumu Ogawa, Takefumi Mori, Kazuhiro Nako, Tsuneo Ishizuka & Sadayoshi Ito. (2008) Reduced Albuminuria with Sarpogrelate Is Accompanied by a Decrease in Monocyte Chemoattractant Protein-1 Levels in Type 2 Diabetes. Clinical Journal of the American Society of Nephrology 3:2, pages 362-368.
Crossref
Crossref
Yoshiyuki Ban, Takuya Watanabe, Akira Miyazaki, Yasuko Nakano, Takashi Tobe, Tsunenori Idei, Takashi Iguchi, Yoshio Ban & Takashi Katagiri. (2007) Impact of increased plasma serotonin levels and carotid atherosclerosis on vascular dementia. Atherosclerosis 195:1, pages 153-159.
Crossref
Crossref
Shinichiro Uchiyama, Yukio Ozaki, Kaneo Satoh, Kazuoki Kondo & Katsuya Nishimaru. (2007) Effect of Sarpogrelate, a 5-HT<sub>2A</sub> Antagonist, on Platelet Aggregation in Patients with Ischemic Stroke: Clinical-Pharmacological Dose-Response Study. Cerebrovascular Diseases 24:2-3, pages 264-270.
Crossref
Crossref
Takurin Akiyoshi, Qi Zhang, Fumihiko Inoue, Osamu Aramaki, Minoru Hatano, Motohide Shimazu, Masaki Kitajima, Nozomu Shirasugi & Masanori Niimi. (2006) Induction of Indefinite Survival of Fully Mismatched Cardiac Allografts and Generation of Regulatory Cells by Sarpogrelate Hydrochloride. Transplantation 82:8, pages 1051-1059.
Crossref
Crossref
Keiichi Hirose, Masatoshi Fujita, Akira Marui, Yoshio Arai, Hisashi Sakaguchi, Yuhong Huang, Shyamal Chandra, Yasuhiko Tabata & Masashi Komeda. (2006) Combined Treatment of Sustained-Release Basic Fibroblast Growth Factor and Sarpogrelate Enhances Collateral Blood Flow Effectively in Rabbit Hindlimb Ischemia. Circulation Journal 70:9, pages 1190-1194.
Crossref
Crossref
K Houkin, N Nakayama, T Nonaka & I Koyanagi. (2016)
The 5-Hydroxytryptamine
2A
Receptor Antagonist Sarpogrelate Hydrochloride Inhibits Acute Platelet Aggregation in Injured Endothelium
. Journal of International Medical Research 34:1, pages 65-72.
Crossref
Crossref
Mónica García, Asunción Morán, Elena Calama, Maria Luisa Martín, Mariette Barthelmebs & Luis San Román. (2005) Diabetes-induced changes in the 5-hydroxytryptamine inhibitory receptors involved in the pressor effect elicited by sympathetic stimulation in the pithed rat. British Journal of Pharmacology 145:5, pages 593-601.
Crossref
Crossref