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Expert Opinion on Investigational Drugs Volume 19, 2010 - Issue 11
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Tumor vasculature as target for therapeutic intervention

Marcel HAM Fens Utrecht University, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutical Sciences, Faculty of Science, PO Box 80.082, 3508 TB Utrecht, The Netherlands +31 30 2539392; +31 30 2517839; [email protected]
,
Gert Storm Utrecht University, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutical Sciences, Faculty of Science, PO Box 80.082, 3508 TB Utrecht, The Netherlands +31 30 2539392; +31 30 2517839; [email protected]
&
Raymond M Schiffelers Utrecht University, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutical Sciences, Faculty of Science, PO Box 80.082, 3508 TB Utrecht, The Netherlands +31 30 2539392; +31 30 2517839; [email protected]
Pages 1321-1338 | Published online: 15 Oct 2010

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Xiangping Deng, Yang Zou, Renbo Liu, Yijiao Peng, Chenglin Ouyang, Junmei Peng, Xiaoyong Lei, Zhizhong Xie, Chong Li & Guotao Tang. (2023) Discovery of a Potential Multi-Target Anti-Tumor Agent via Structural Modification on Flavonoid. Polycyclic Aromatic Compounds 43:2, pages 980-999.
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Zhu-Gui Zhou, Dong-Dong Li, Ying Chen, Xi Chen & Ruo-Jun Man. (2022) Discussion on the Structural Modification and Anti-tumor Activity of Flavonoids. Current Topics in Medicinal Chemistry 22:7, pages 561-577.
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Xueyan Sun, Yijiao Peng, Jingduo Zhao, Zhizhong Xie, Xiaoyong Lei & Guotao Tang. (2021) Discovery and development of tumor glycolysis rate-limiting enzyme inhibitors. Bioorganic Chemistry 112, pages 104891.
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Xiangping Deng, Yiyuan Pi, Zhongli Li, Runde Xiong, Juan Liu, Jingduo Zhao, Zhizhong Xie, Xiaoyong Lei & Guotao Tang. (2020) FB-15 inhibits MGC-803 cells growth by regulating energy metabolism. Chemico-Biological Interactions 327, pages 109186.
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Xiangping Deng, Renbo Liu, Junjian Li, Zhongli Li, Juan Liu, Runde Xiong, Xiaoyong Lei, Xing Zheng, Zhizhong Xie & Guotao Tang. (2019) Design, synthesis, and preliminary biological evaluation of 3′,4′,5′-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents. New Journal of Chemistry 43:4, pages 1874-1884.
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Xiangping Deng, Zhongli Li, Runde Xiong, Juan Liu, Renbo Liu, Junmei Peng, Yanming Chen, Xiaoyong Lei, Xuan Cao, Xing Zheng, Zhizhong Xie & Guotao Tang. (2019) FS-7 inhibits MGC-803 cells growth in vitro and in vivo via down-regulating glycolysis. Biomedicine & Pharmacotherapy 109, pages 1659-1669.
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Lili Tian, Kangjie Xie, Donglai Sheng, Xiaoqing Wan & Guofu Zhu. (2017) Antiangiogenic effects of oridonin. BMC Complementary and Alternative Medicine 17:1.
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Kellsye L. Fabian & Walter J. Storkus. 2017. Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy. Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy 191 211 .
Christine A. Herdman, Tracy E. Strecker, Rajendra P. Tanpure, Zhi Chen, Alex Winters, Jeni Gerberich, Li Liu, Ernest Hamel, Ralph P. Mason, David J. Chaplin, Mary Lynn Trawick & Kevin G. Pinney. (2016) Synthesis and biological evaluation of benzocyclooctene-based and indene-based anticancer agents that function as inhibitors of tubulin polymerization. Med. Chem. Commun. 7:12, pages 2418-2427.
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Yuting Lin, Harald Paganetti, Stephen J. McMahon & Jan Schuemann. (2015) Gold nanoparticle induced vasculature damage in radiotherapy: Comparing protons, megavoltage photons, and kilovoltage photons. Medical Physics 42:10, pages 5890-5902.
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Dong Hyun Jo, Jin Hyoung Kim, Kyu-Won Kim, Young-Ger Suh & Jeong Hun Kim. (2014) Allosteric regulation of pathologic angiogenesis: potential application for angiogenesis-related blindness. Archives of Pharmacal Research 37:3, pages 285-298.
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Ligong Liu, Caiping Li, Siska Cochran, Shane Jimmink & Vito Ferro. (2012) Synthesis of a Heparan Sulfate Mimetic Library Targeting FGF and VEGF via Click Chemistry on a Monosaccharide Template. ChemMedChem 7:7, pages 1267-1275.
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Ajit S. Narang & Sailesh Varia. (2011) Role of tumor vascular architecture in drug delivery. Advanced Drug Delivery Reviews 63:8, pages 640-658.
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Raymond M. Schiffelers, Tjitske K. van der Vaart & Gert Storm. (2011) Neovascular Age-Related Macular Degeneration. BioDrugs 25:3, pages 171-189.
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Agata Matejuk, Qixin Leng, Szu-Ting Chou & Archibald J Mixson. (2011) Vaccines targeting the neovasculature of tumors. Vascular Cell 3:1, pages 7.
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Ralph P. Mason, Dawen Zhao, Li Liu, Mary Lynn Trawick & Kevin G. Pinney. (2011) A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment. Integrative Biology 3:4, pages 375.
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