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Drug Evaluations

Sorafenib in melanoma

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Pages 557-568 | Published online: 07 Mar 2012

Keep up to date with the latest research on this topic with citation updates for this article.

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Hee Man Kim, Sun A Kim, Soo Been Park, Jae Hee Cho & Si Young Song. (2017) Sorafenib inhibits 5-fluorouracil-resistant gastric cancer cell growth. Scandinavian Journal of Gastroenterology 52:5, pages 577-584.
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Sarah E. Fenton, Jeffrey A. Sosman & Sunandana Chandra. (2017) Emerging growth factor receptor antagonists for the treatment of advanced melanoma. Expert Opinion on Emerging Drugs 22:2, pages 165-174.
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Massimo Gentile, Massimo Martino, Anna Grazia Recchia, Ernesto Vigna, Lucio Morabito & Fortunato Morabito. (2016) Sorafenib for the treatment of multiple myeloma. Expert Opinion on Investigational Drugs 25:6, pages 743-749.
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Karissa M Johnston, Emily McPherson, Katherine Osenenko, Joanna Vergidis, Adrian R Levy & Stuart Peacock. (2015) Cost–effectiveness of therapies for melanoma. Expert Review of Pharmacoeconomics & Outcomes Research 15:2, pages 229-242.
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Mirjana Urosevic-Maiwald, Marjam J Barysch, Phil F Cheng, Maria B Karpova, Hans Steinert, Michal J Okoniewski & Reinhard Dummer. (2015) In vivo profiling reveals immunomodulatory effects of sorafenib and dacarbazine on melanoma. OncoImmunology 4:2.
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Umberto Leone Roberti Maggiore, Mario Valenzano Menada, Pier Luigi Venturini & Simone Ferrero. (2013) Sorafenib for ovarian cancer. Expert Opinion on Investigational Drugs 22:8, pages 1049-1062.
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Malgorzata Mackiewicz-Wysocka, Jakub Zolnierek & Piotr J Wysocki. (2013) New therapeutic options in systemic treatment of advanced cutaneous melanoma. Expert Opinion on Investigational Drugs 22:2, pages 181-190.
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Diwakar Davar & John Munn Kirkwood. (2012) New therapies in the treatment of melanoma. Expert Opinion on Investigational Drugs 21:11, pages 1643-1659.
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Abdalla R. Mohamed & Ahmed M. El Kerdawy. (2022) A Perspective Study on the RTK, PI3K, B‐Raf, CDK and the Multi‐Protein Targeting in Medicinal Chemistry. Chemistry & Biodiversity 19:10.
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Hongyu Kong, Rong Zhang, Qinghe Jing, Yu Liang, Qiao Zhuo, Bo Li, Shujie Zhang, Weiliang Zhu & Chen Zhao. (2022) Intravitreal injection of EV11, a novel aryl ketone amide, inhibits choroidal neovascularization via AKT/ERK1/2 pathway. Microvascular Research 143, pages 104401.
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Francesca Laneri, Adriana C. E. Graziano, Mimimorena Seggio, Aurore Fraix, Milo Malanga, Szabolcs Béni, Giuseppe Longobardi, Claudia Conte, Fabiana Quaglia & Salvatore Sortino. (2022) Enhancing the Anticancer Activity of Sorafenib through Its Combination with a Nitric Oxide Photodelivering β-Cyclodextrin Polymer. Molecules 27:6, pages 1918.
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Haoxue Zhang, Yuyao Liu, Delin Hu & Shengxiu Liu. (2022) Identification of Novel Molecular Therapeutic Targets and Their Potential Prognostic Biomarkers Based on Cytolytic Activity in Skin Cutaneous Melanoma. Frontiers in Oncology 12.
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Sarbjit Singh, Divya Utreja & Vimal Kumar. (2021) Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy. Medicinal Chemistry Research 31:1, pages 1-25.
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A.G. Nerkar. (2021) Metastatic melanomas: Treatment overview. Current Trends in Pharmacy and Pharmaceutical Chemistry 3:4, pages 50-55.
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Angela Bonaccorso, Veronica Pepe, Cristina Zappulla, Cinzia Cimino, Angelo Pricoco, Giovanni Puglisi, Francesco Giuliano, Rosario Pignatello & Claudia Carbone. (2021) Sorafenib Repurposing for Ophthalmic Delivery by Lipid Nanoparticles: A Preliminary Study. Pharmaceutics 13:11, pages 1956.
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Arkadiusz Z. Dudek, Kate Baxstrom, Sushma Bharadwaj, Anne Blaes, Amit Kulkarni, Emil Lou, Vijeyaluxmy Nehru, Emma Rabinovich, Ardaman Shergill & Maya Viner. 2020. Precision Medicine in Oncology. Precision Medicine in Oncology 1 60 .
Lucie Heinzerling, Anke Hartmann & Martina HundLucie Heinzerling, Anke Hartmann & Martina Hund. 2019. Medikamentöse Tumortherapie in der Dermato-Onkologie. Medikamentöse Tumortherapie in der Dermato-Onkologie 45 134 .
Andreia V. Pinho, Jenny H. Lee & Helen Rizos. 2019. Current Applications for Overcoming Resistance to Targeted Therapies. Current Applications for Overcoming Resistance to Targeted Therapies 223 258 .
Alice Y. Zhou & Douglas B. Johnson. (2017) Combinatorial Therapies in Melanoma: MAPK Inhibitors and Beyond. American Journal of Clinical Dermatology 19:2, pages 181-193.
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Philip A. Harris. 2018. Cancer II. Cancer II 105 139 .
S. Thurneysen, P.F. Cheng, H.W. Nagel, M. Kunz, N. Jaberg-Bentele, M. Nägeli, M. Ziegler, E. Guenova, S.M. Goldinger, J. Mangana, M.P. Levesque & R. Dummer. (2016) An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel. British Journal of Dermatology 175:5, pages 966-978.
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Nicole R. Dominiak, Mark R. Wick & M. Timothy Smith. (2016) Mucosal melanomas: Site-specific information, comparisons with cutaneous tumors, and differential diagnosis. Seminars in Diagnostic Pathology 33:4, pages 191-197.
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Isabella C. Glitza, Dae Won Kim, Young Kwang Chae & Kevin B. Kim. 2016. Genetics of Melanoma. Genetics of Melanoma 237 265 .
J. S. Fowles, C. L. Denton & D. L. Gustafson. (2015) Comparative analysis of MAPK and PI3K/AKT pathway activation and inhibition in human and canine melanoma. Veterinary and Comparative Oncology 13:3, pages 288-304.
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John G. Moffat, Joachim Rudolph & David Bailey. (2014) Phenotypic screening in cancer drug discovery — past, present and future. Nature Reviews Drug Discovery 13:8, pages 588-602.
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Jia-Hui Chu, Cui-Rong Zhao, Zhi-Yu Song, Rui-Qi Wang, Yi-Zhuo Qin, Wen-Bao Li & Xian-Jun Qu. (2014) 1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than sorafenib. Biomedicine & Pharmacotherapy 68:3, pages 335-341.
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Abraham Amsterdam, Calanit Raanan, Nava Polin, Ehud Melzer, David Givol & Letizia Schreiber. (2014) Modulation of c-kit expression in pancreatic adenocarcinoma: A novel stem cell marker responsible for the progression of the disease. Acta Histochemica 116:1, pages 197-203.
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Lucie Heinzerling, Anke Hartmann, Martina Hund & Gerold SchulerLucie Heinzerling, Anke Hartmann, Martina Hund & Gerold Schuler. 2014. Medikamentöse Tumortherapie in der Dermato-Onkologie. Medikamentöse Tumortherapie in der Dermato-Onkologie 31 97 .
Michalis Alevizakos, Serafim Kaltsas & Konstantinos N. Syrigos. (2013) The VEGF pathway in lung cancer. Cancer Chemotherapy and Pharmacology 72:6, pages 1169-1181.
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Antonino Mazzaglia, Maria Luisa Bondì, Angela Scala, Francesca Zito, Giovanna Barbieri, Francesco Crea, Giuseppina Vianelli, Placido Mineo, Tiziana Fiore, Claudia Pellerito, Lorenzo Pellerito & Maria Assunta Costa. (2013) Supramolecular Assemblies Based on Complexes of Nonionic Amphiphilic Cyclodextrins and a meso -Tetra(4-sulfonatophenyl)porphine Tributyltin(IV) Derivative: Potential Nanotherapeutics against Melanoma . Biomacromolecules 14:11, pages 3820-3829.
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Francesca Pretto & Dario Neri. (2013) Pharmacotherapy of metastatic melanoma: Emerging trends and opportunities for a cure. Pharmacology & Therapeutics 139:3, pages 405-411.
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Victoria K. Hill, Jared J. Gartner, Yardena SamuelsAlisa M. Goldstein. (2013) The Genetics of Melanoma: Recent Advances. Annual Review of Genomics and Human Genetics 14:1, pages 257-279.
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Snezana Djordjevic & Paul C. Driscoll. (2013) Targeting VEGF signalling via the neuropilin co-receptor. Drug Discovery Today 18:9-10, pages 447-455.
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David Chandler & Anthony Bewley. (2013) Biologics in Dermatology. Pharmaceuticals 6:4, pages 557-578.
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Alyson K. Freeman & Deborah K. Morrison. 2013. Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy. Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy 47 67 .

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