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Volume 21, Issue 4

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 21, Issue 4 (2012)

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Expert Opinion on Investigational Drugs, Volume 21, Issue 4 (2012)

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Research Article

Article

Page: 1

Published online: 10 Mar 2012

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Editorial

Nucleoside and nucleobase analogs in cancer treatment: not only sapacitabine, but also gemcitabine

Franco Muggia, Isabela Diaz & Godefridus J Peters

Pages: 403-408

Published online: 09 Mar 2012

AbstractforNucleoside and nucleobase analogs in cancer treatment: not only sapacitabine, but also gemcitabine | Full Text | References | PDF (254.7 KB)

3751 Views
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Free Access

Reviews

Review Article

Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia

Kumudha Balakrishnan PhD & Varsha Gandhi PhD

Pages: 409-423

Published online: 09 Mar 2012

AbstractforProtein kinases: emerging therapeutic targets in chronic lymphocytic leukemia | Full Text | References | PDF (623.5 KB)

397 Views
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Review Article

PIM1 kinase as a target for cancer therapy

Anna Lena Merkel, Eric Meggers & Matthias Ocker

Pages: 425-436

Published online: 04 Mar 2012

AbstractforPIM1 kinase as a target for cancer therapy | Full Text | References | PDF (570.7 KB)

1276 Views
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Review Article

Pemetrexed disodium in ovarian cancer treatment

M Morotti MD, M Valenzano Menada MD, PL Venturini MD, S Mammoliti MD & S Ferrero MD PhD

Pages: 437-449

Published online: 13 Feb 2012

AbstractforPemetrexed disodium in ovarian cancer treatment | Full Text | References | PDF (239.1 KB)

262 Views
7 CrossRef citations
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Review Article

Novel targets for VEGF-independent anti-angiogenic drugs

Marco Petrillo, Giovanni Scambia & Gabriella Ferrandina MD

Pages: 451-472

Published online: 20 Feb 2012

AbstractforNovel targets for VEGF-independent anti-angiogenic drugs | Full Text | References | PDF (432.6 KB)

863 Views
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Review Article

Current investigational drugs in psoriasis

Caitriona Ryan MB BCh BAO BMedSc, Amanda Abramson MD, Mahir Patel MD & Alan Menter MD

Pages: 473-487

Published online: 08 Mar 2012

AbstractforCurrent investigational drugs in psoriasis | Full Text | References | PDF (258.6 KB)

948 Views
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Review Article

Stampidine as a promising antiretroviral drug candidate for pre-exposure prophylaxis against sexually transmitted HIV/AIDS

Fatih M Uckun, Pedro Cahn, Sanjive Qazi & Osmond D'Cruz

Pages: 489-500

Published online: 24 Feb 2012

AbstractforStampidine as a promising antiretroviral drug candidate for pre-exposure prophylaxis against sexually transmitted HIV/AIDS | Full Text | References | PDF (310.7 KB)

206 Views
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Review Article

Angiotensin II type 2 receptor agonists: where should they be applied?

Koen Verdonk, A H Jan Danser & Joep H M van Esch

Pages: 501-513

Published online: 21 Feb 2012

AbstractforAngiotensin II type 2 receptor agonists: where should they be applied? | Full Text | References | PDF (307.9 KB)

951 Views
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Drug Evaluations

Article

Tedizolid (TR-701): a new oxazolidinone with enhanced potency

Zeina A. Kanafani & G. Ralph Corey

Pages: 515-522

Published online: 13 Feb 2012

Abstractfor Tedizolid (TR-701): a new oxazolidinone with enhanced potency | Full Text | References | PDF (222.4 KB)

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Article

Dolutegravir for the treatment of HIV

Christine Katlama MD & Robert Murphy MD

Pages: 523-530

Published online: 02 Mar 2012

Abstractfor Dolutegravir for the treatment of HIV | Full Text | References | PDF (312.1 KB)

825 Views
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Article

Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma

Sapna P Patel MD & Kevin B Kim MD

Pages: 531-539

Published online: 07 Mar 2012

Abstractfor Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma | Full Text | References | PDF (381.9 KB)

714 Views
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Article

Sapacitabine for cancer

Xiaojun Liu, Hagop Kantarjian & William Plunkett

Pages: 541-555

Published online: 14 Feb 2012

Abstractfor Sapacitabine for cancer | Full Text | References | PDF (404.1 KB)

316 Views
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Article

Sorafenib in melanoma

Joanna Mangana, Mitchell P Levesque, Maria B Karpova & Reinhard Dummer

Pages: 557-568

Published online: 07 Mar 2012

Abstractfor Sorafenib in melanoma | Full Text | References | PDF (355.4 KB)

820 Views
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Key Paper Evaluation

Article

Dalcetrapib – restoring belief in modulating CETP as a beneficial mechanism in cardiovascular disease

Evaluation of Fayad ZA, Mani V, Woodward M et al. Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial. Lancet 2011;378:1547-59

Sheila A Doggrell PhDDSc

Pages: 569-573

Published online: 13 Feb 2012

AbstractforDalcetrapib – restoring belief in modulating CETP as a beneficial mechanism in cardiovascular disease | Full Text | References | PDF (180.2 KB)

255 Views
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Expert Opinion on Investigational Drugs (Vol.21, Iss.4, 2012)

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