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Efficacy of oral cobalamin (vitamin B12) therapy

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Pages 249-256 | Published online: 21 Jan 2010

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Gaetano Bergamaschi, Flavio Caprioli, Marco Vincenzo Lenti, Luca Elli, Franco Radaelli, Emanuele Rondonotti, Caterina Mengoli, Emanuela Miceli, Chiara Ricci, Sandro Ardizzone, Maurizio Vecchi & Antonio Di Sabatino. (2022) Pathophysiology and therapeutic management of anemia in gastrointestinal disorders. Expert Review of Gastroenterology & Hepatology 16:7, pages 625-637.
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Artem Minalyan, Jihane N Benhammou, Aida Artashesyan, Michael S Lewis & Joseph R Pisegna. (2017) Autoimmune atrophic gastritis: current perspectives. Clinical and Experimental Gastroenterology 10, pages 19-27.
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Emmanuel Andres & Khalid Serraj. (2012) Optimal management of pernicious anemia. Journal of Blood Medicine 3, pages 97-103.
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Articles from other publishers (58)

Mohammad Ibrahim, Shabina Khan, Sanchita Pathak, Mohd Mazhar & Harpreet Singh. (2023) Vitamin B-Complex and its Relationship with the Health of Vegetarian People. Natural Resources for Human Health 3:3, pages 342-354.
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Gábor Mikala, Zsuzsanna Szemlaky & Andrea Ceglédi. (2022) Az emelkedett szérum B12-vitamin-szint klinikai jelentősége. Hematológia–Transzfuziológia 55:1, pages 17-22.
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Wei Li, Jing Zhao, Ling-Ling Zhu & You-Fan Peng. (2022) Serum vitamin B12 levels and glycemic fluctuation in patients with type 2 diabetes mellitus. Therapeutic Advances in Endocrinology and Metabolism 13, pages 204201882211028.
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Wynn Thein, Wah Wah Po, Won Seok Choi & Uy Dong Sohn. (2021) Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches. Biomolecules & Therapeutics 29:4, pages 353-364.
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Alessandra Vincenti, Laura Bertuzzo, Antonio Limitone, Giuseppe D’Antona & Hellas Cena. (2021) Perspective: Practical Approach to Preventing Subclinical B12 Deficiency in Elderly Population. Nutrients 13:6, pages 1913.
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Yuanyuan Xiang, Lei Li, Xiaotong Ma, Shan Li, Yuan Xue, Peng Yan, Meijie Chen & Junwei Wu. (2021) Recreational Nitrous Oxide Abuse: Prevalence, Neurotoxicity, and Treatment. Neurotoxicity Research 39:3, pages 975-985.
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Joseph Boachie, Antonysunil Adaikalakoteswari, Ilona Goljan, Jinous Samavat, Felino R. Cagampang & Ponnusamy Saravanan. (2021) Intracellular and Tissue Levels of Vitamin B12 in Hepatocytes Are Modulated by CD320 Receptor and TCN2 Transporter. International Journal of Molecular Sciences 22:6, pages 3089.
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Anjali SharmaDrDrAnand DeshpandeDrDrChhavi SauparnaDrDrZeeshan AhmedDrDr. (2021) CLINICAL AND EPIDEMIOLOGICAL PROFILE OF CHILDREN WITH MEGALOBLASTIC ANEMIA AT A TERTIARY CARE HOSPITAL IN WESTERN INDIA: A CROSS SECTIONAL STUDY. GLOBAL JOURNAL FOR RESEARCH ANALYSIS, pages 35-38.
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Zuzanna Rzepka, Jakub Rok, Mateusz Maszczyk, Artur Beberok, Justyna Hermanowicz, Dariusz Pawlak, Dorota Gryko & Dorota Wrześniok. (2021) Response of Human Glioblastoma Cells to Vitamin B12 Deficiency: A Study Using the Non-Toxic Cobalamin Antagonist. Biology 10:1, pages 69.
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О.В. Рыбина, А.В. Губкин, В.Т. Сахин & О.А. Рукавицын. (2020) Anemic Syndrome in Gastroenterological Diseases: Problems and Solutions. Гематология. Трансфузиология. Восточная Европа:3, pages 357-371.
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Marco Vincenzo Lenti, Massimo Rugge, Edith Lahner, Emanuela Miceli, Ban-Hock Toh, Robert M. Genta, Christophe De Block, Chaim Hershko & Antonio Di Sabatino. (2020) Autoimmune gastritis. Nature Reviews Disease Primers 6:1.
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E Andrès, A -A Zulfiqar & T Vogel. (2020) State of the art review: oral and nasal vitamin B12 therapy in the elderly. QJM: An International Journal of Medicine 113:1, pages 5-15.
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Jeffrey K. Griffiths. 2020. Hunter's Tropical Medicine and Emerging Infectious Diseases. Hunter's Tropical Medicine and Emerging Infectious Diseases 1042 1047 .
Mila Dimitrova Kovacheva-Slavova, Todor Asenov Angelov, Hristo Yankov Valkov, Hristo Ilianov Iliev & Borislav Georgiev Vladimirov. 2019. Gastritis - New Approaches and Treatments. Gastritis - New Approaches and Treatments.
Margaux Lafaurie & François Montastruc. (2019) Intérêt d’une consultation médicale de pharmacovigilance : exemple de la carence en vitamine B12 avec la metformine. La Presse Médicale 48:11, pages 1216-1221.
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K. V. Karthika & Hara Prasad Pati. 2019. Hematopathology. Hematopathology 49 57 .
Emmanuel Andrès, Thomas Vogel & Abrar Zulfiqar. 2019. Anemia in the Young and Old. Anemia in the Young and Old 179 193 .
Emmanuel Andrès, Abrar-Ahmad Zulfiqar, Khalid Serraj, Thomas Vogel & Georges Kaltenbach. (2018) Systematic Review and Pragmatic Clinical Approach to Oral and Nasal Vitamin B12 (Cobalamin) Treatment in Patients with Vitamin B12 Deficiency Related to Gastrointestinal Disorders. Journal of Clinical Medicine 7:10, pages 304.
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Gaetano Bergamaschi, Antonio Di Sabatino & Gino R. Corazza. (2018) Pathogenesis, diagnosis and treatment of anaemia in immune‐mediated gastrointestinal disorders. British Journal of Haematology 182:3, pages 319-329.
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A.-A. Zulfiqar, X. Sui Seng, E. Duhamel, N. Kadri, J. Doucet & E. Andrès. (2018) Hypovitaminose B12 chez les sujets âgés : mise au point clinique, biologique et étiologique. NPG Neurologie - Psychiatrie - Gériatrie 18:105, pages 149-154.
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Haiyan Wang, Linyi Li, Ling Ling Qin, Yanan Song, Josep Vidal-Alaball & Tong Hua Liu. (2018) Oral vitamin B 12 versus intramuscular vitamin B 12 for vitamin B 12 deficiency . Cochrane Database of Systematic Reviews 2018:3.
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Olaniyi John Ayodele. 2018. Current Topics in Anemia. Current Topics in Anemia.
Yong-Jiang Li, Jian-Jun Ou, Ya-Min Li & Da-Xiong Xiang. (2017) Dietary Supplement for Core Symptoms of Autism Spectrum Disorder: Where Are We Now and Where Should We Go?. Frontiers in Psychiatry 8.
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Neeraj Kumar. (2017) Nutrients and Neurology. CONTINUUM: Lifelong Learning in Neurology 23:3, pages 822-861.
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Farhanah Yousaf, Bruce Spinowitz, Chaim Charytan & Marilyn Galler. (2017) Pernicious Anemia Associated Cobalamin Deficiency and Thrombotic Microangiopathy: Case Report and Review of the Literature. Case Reports in Medicine 2017, pages 1-8.
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Sonia Mahey, Rakesh Kumar, Rohit Arora, Jyoti Mahajan, Saroj Arora, Renu Bhardwaj & Ashwani Kumar Thukral. (2016) Effect of cobalt(II) chloride hexahydrate on some human cancer cell lines. SpringerPlus 5:1.
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Zouhayr Souirti, Mouna Loukili, Imar D. Soudy, Kaies Rtibi, Aslihan Özel, Nicolas Limas-Nzouzi, Seloua El Ouezzani & Bruno Eto. (2016) Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B 12 deficiency with neurological symptoms . Fundamental & Clinical Pharmacology 30:6, pages 568-576.
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Vijaya Kancherla, Joshua V. Garn, Neil A. Zakai, Rebecca S. Williamson, Winn T. Cashion, Oluwaseun Odewole, Suzanne E. Judd & Godfrey P. Oakley. (2016) Multivitamin Use and Serum Vitamin B12 Concentrations in Older-Adult Metformin Users in REGARDS, 2003-2007. PLOS ONE 11:8, pages e0160802.
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E. Andrès, T. Vogel, G. Kaltenbach & P.-O. Lang. (2016) Malabsorption des cobalamines alimentaires et carence en vitamine B12 chez l’adulte et chez le sujet âgé : quel est le problème ?. La Revue de Médecine Interne 37:8, pages 511-513.
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E. Andrès. (2016) Syndrome de maldigestion des cobalamines alimentaires - Carence en vitamine B12 - Metformine. Médecine des Maladies Métaboliques 10:3, pages 226-230.
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E. Andrès & N. Dali-Youcef. 2016. Encyclopedia of Food and Health. Encyclopedia of Food and Health 160 165 .
Emmanuel Andrès. (2015) Cobalamin deficiency as an extra intestinal manifestation of Helicobacter pylori infection . World Journal of Gastroenterology 21:11, pages 3447-3448.
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Johanna T. Dwyer, Rebecca Costello, Joyce Merkel & Paul M. Coates. 2015. Handbook of Clinical Nutrition and Aging. Handbook of Clinical Nutrition and Aging 375 424 .
Monique P.H. Tillemans, Eline M.V.J. Donders, Sjoerd L. Verweij, Ruud T.M. Van der Hoeven & Kees J. Kalisvaart. (2014) Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial. Current Therapeutic Research 76, pages 21-25.
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Lingtak-Neander Chan & Leigh Ann Mike. (2014) The Science and Practice of Micronutrient Supplementations in Nutritional Anemia. Journal of Parenteral and Enteral Nutrition 38:6, pages 656-672.
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Neeraj Kumar. 2014. Neurologic Aspects of Systemic Disease Part II. Neurologic Aspects of Systemic Disease Part II 915 926 .
Shounak Majumder, Jose Soriano, Allan Louie Cruz & Constantin A. Dasanu. (2013) Vitamin B12 deficiency in patients undergoing bariatric surgery: Preventive strategies and key recommendations. Surgery for Obesity and Related Diseases 9:6, pages 1013-1019.
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Emmanuel Andrès, Khalid Serraj, Laure Federici, Thomas Vogel & Georges Kaltenbach. (2013) Anemia in elderly patients: New insight into an old disorder. Geriatrics & Gerontology International 13:3, pages 519-527.
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E. Andrès, K. Serraj, J. Zhu & A.J.M. Vermorken. (2022) The pathophysiology of elevated vitamin B12 in clinical practice. QJM: An International Journal of Medicine 106:6, pages 505-515.
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Renata Kozyraki & Olivier Cases. (2013) Vitamin B12 absorption: Mammalian physiology and acquired and inherited disorders. Biochimie 95:5, pages 1002-1007.
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M. Azam Mansoor, Tonje Holte Stea, Jørn Schneede & Andreas Reine. (2013) Early Biochemical and Hematological Response to Intramuscular Cyanocobalamin Therapy in Vitamin B<sub>12</sub>-Deficient Patients. Annals of Nutrition and Metabolism 62:4, pages 347-353.
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Jeffrey K Griffiths. 2013. Hunter's Tropical Medicine and Emerging Infectious Disease. Hunter's Tropical Medicine and Emerging Infectious Disease 997 1002 .
Amanda Gates, Stefanie Ferreri & Daniel L. Krinsky. (2012) Recommending OTC vitamin B12. Pharmacy Today 18:11, pages 22.
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Setareh Shahab-Ferdows, Miriam A. Anaya-Loyola, Haydé Vergara-Castañeda, Jorge L. Rosado, William R. Keyes, John W. Newman, Joshua W. Miller & Lindsay H. Allen. (2012) Vitamin B-12 Supplementation of Rural Mexican Women Changes Biochemical Vitamin B-12 Status Indicators but Does Not Affect Hematology or a Bone Turnover Marker4. The Journal of Nutrition 142:10, pages 1881-1887.
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Emmanuel Andrès. (2012) Oral cobalamin therapy: It may be perhaps time to propose international recommendations?. La Presse Médicale 41:10, pages 895-898.
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Sally P. Stabler. 2012. Present Knowledge in Nutrition. Present Knowledge in Nutrition 343 358 .
Kira Leishear, Robert M. Boudreau, Stephanie A. Studenski, 
Luigi Ferrucci, Caterina Rosano, Nathalie de Rekeneire, Denise K. Houston, Stephen B. Kritchevsky, Ann V. Schwartz, Aaron I. Vinik, Eva Hogervorst, Kristine Yaffe, Tamara B. Harris, Anne B. Newman & Elsa S. Strotmeyer. (2012) Relationship Between Vitamin B 12 and Sensory and Motor Peripheral Nerve Function in Older Adults . Journal of the American Geriatrics Society 60:6, pages 1057-1063.
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C. Mirkazemi, Gregory M. Peterson, P. C. Tenni & S. L. Jackson. (2011) Vitamin B12 deficiency in Australian residential aged care facilities. The journal of nutrition, health & aging 16:3, pages 277-280.
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S. Sviri, R. Khalaila, S. Daher, A. Bayya, D.M. Linton, I. Stav & P.V. van Heerden. (2012) Increased Vitamin B12 levels are associated with mortality in critically ill medical patients. Clinical Nutrition 31:1, pages 53-59.
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Antonio Macciò & Clelia Madeddu. (2012) Management of Anemia of Inflammation in the Elderly. Anemia 2012, pages 1-20.
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Barbara S. Koppel. 2012. Goldman's Cecil Medicine. Goldman's Cecil Medicine 2382 2386 .
Aśok C. Antony. 2012. Goldman's Cecil Medicine. Goldman's Cecil Medicine 1075 1083 .
Emmanuel Andrès & Mustapha Mecili. (2011) Oral Vitamin B12 Therapy. Annals of Surgical Oncology 18:S3, pages 196-198.
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Bernard Favrat, Paul Vaucher, Lilli Herzig, Bernard Burnand, Giuseppa Ali, Olivier Boulat, Thomas Bischoff & François Verdon. (2011) Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial. BMC Family Practice 12:1.
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M. Cristina Castelli, Diane F. Wong, Kristen Friedman & M. Gary I. Riley. (2011) Pharmacokinetics of Oral Cyanocobalamin Formulated With Sodium N-[8-(2-hydroxybenzoyl)amino]caprylate (SNAC): An Open-Label, Randomized, Single-Dose, Parallel-Group Study in Healthy Male Subjects. Clinical Therapeutics 33:7, pages 934-945.
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E. Andrès & K. Serraj. (2011) Anémies macrocytaires carentielles de l'adulte et du sujet âgé. EMC - Hématologie 6:4, pages 1-11.
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Arianna Troilo, Mustapha Mecili, Ecaterina Ciobanu, Vieri Boddi, Mario M. D’Elios & Emmanuel Andrès. (2010) Efficacité et tolérance de la vitamine B12 par voie orale chez 31 patients avec une maladie de Biermer ou une maldigestion des cobalamines alimentaires. La Presse Médicale 39:12, pages e273-e279.
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Mary P. Cadogan. (2010) Functional Implications of Vitamin B 12 Deficiency . Journal of Gerontological Nursing 36:6, pages 16-21.
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