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Expert Opinion on Pharmacotherapy Volume 7, 2006 - Issue 16
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Review

Point mutations of protein kinases and individualised cancer therapy

Michael Davies Fellow, University of Texas – M D Anderson Cancer Center, Department of Medical Oncology, 1515 Holcombe Blvd, Unit 10, Houston, TX 77030, USA. [email protected]
,
Bryan Hennessy Assistant Professor, Gynecologic Medical Oncology, University of Texas – M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 10, Houston, TX 77030, USA
&
Gordon B Mills Professor, Chairman, University of Texas – M. D. Anderson Cancer Center, Department of Molecular Therapeutics, 151 Holcombe Blvd, Unit 950, Houston, TX 77030, USA
Pages 2243-2261 | Published online: 24 Oct 2006

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Yang Ni, Francesco C. Stingo, Min Jin Ha, Rehan Akbani & Veerabhadran Baladandayuthapani. (2019) Bayesian Hierarchical Varying-Sparsity Regression Models with Application to Cancer Proteogenomics. Journal of the American Statistical Association 114:525, pages 48-60.
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Yang Ni, Francesco C. Stingo & Veerabhadran Baladandayuthapani. (2017) Sparse Multi-Dimensional Graphical Models: A Unified Bayesian Framework. Journal of the American Statistical Association 112:518, pages 779-793.
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Martin H Fenner, Gernot Beutel & Viktor Grünwald. (2008) Targeted therapies for patients with germ cell tumors. Expert Opinion on Investigational Drugs 17:4, pages 511-522.
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Magdalena Smereczańska, Natalia Domian, Grzegorz Młynarczyk & Irena Kasacka. (2023) The Effect of CacyBP/SIP on the Phosphorylation of ERK1/2 and p38 Kinases in Clear Cell Renal Cell Carcinoma. International Journal of Molecular Sciences 24:12, pages 10362.
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Sayantan Banerjee, Rehan Akbani & Veerabhadran Baladandayuthapani. (2019) Spectral clustering via sparse graph structure learning with application to proteomic signaling networks in cancer. Computational Statistics & Data Analysis 132, pages 46-69.
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Natalie Büel-Drabe, Hans Steinert, Hanspeter Moergeli, Steffi Weidt, Annina Seiler & Josef Jenewein. (2017) Thyroid cancer has a small impact on patient–partner relationships and their frequency of sexual activity. Palliative and Supportive Care 16:3, pages 335-346.
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Michael A. Davies. 2015. BRAF Targets in Melanoma. BRAF Targets in Melanoma 105 135 .
Veerabhadran Baladandayuthapani, Rajesh Talluri, Yuan Ji, Kevin R. Coombes, Yiling Lu, Bryan T. Hennessy, Michael A. Davies & Bani K. Mallick. (2014) Bayesian sparse graphical models for classification with application to protein expression data. The Annals of Applied Statistics 8:3.
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Lin ZhangJeffrey S. MorrisJiexin ZhangRobert Z. OrlowskiVeerabhadran Baladandayuthapani. (2014) Bayesian Joint Selection of Genes and Pathways: Applications in Multiple Myeloma Genomics. Cancer Informatics 13s2, pages CIN.S13787.
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Michael A. Davies. 2012. Current Challenges in Personalized Cancer Medicine. Current Challenges in Personalized Cancer Medicine 109 142 .
Michael A. Davies. 2012. Targeted Therapeutics in Melanoma. Targeted Therapeutics in Melanoma 3 15 .
Michael A. Davies. (2011) Regulation, Role, and Targeting of Akt in Cancer. Journal of Clinical Oncology 29:35, pages 4715-4717.
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Alan Ashworth, Christopher J. Lord & Jorge S. Reis-Filho. (2011) Genetic Interactions in Cancer Progression and Treatment. Cell 145:1, pages 30-38.
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Michael A. Davies & Jeffrey E. Gershenwald. (2011) Targeted Therapy for Melanoma: A Primer. Surgical Oncology Clinics of North America 20:1, pages 165-180.
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M A Davies & Y Samuels. (2010) Analysis of the genome to personalize therapy for melanoma. Oncogene 29:41, pages 5545-5555.
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Scott E. Woodman, Jonathan C. Trent, Katherine Stemke-Hale, Alexander J. Lazar, Sabrina Pricl, Giovanni M. Pavan, Maurizio Fermeglia, Y.N. Vashisht Gopal, Dan Yang, Donald A. Podoloff, Doina Ivan, Kevin B. Kim, Nicholas Papadopoulos, Patrick Hwu, Gordon B. Mills & Michael A. Davies. (2009) Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates . Molecular Cancer Therapeutics 8:8, pages 2079-2085.
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Donald D. Rao, John S. Vorhies, Neil Senzer & John Nemunaitis. (2009) siRNA vs. shRNA: Similarities and differences. Advanced Drug Delivery Reviews 61:9, pages 746-759.
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S. J. Enna & M. Williams. (2009) Challenges in the Search for Drugs to Treat Central Nervous System Disorders. Journal of Pharmacology and Experimental Therapeutics 329:2, pages 404-411.
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Wa Xian, Leontios Pappas, Darshan Pandya, Laura M. Selfors, Patrick W. Derksen, Michiel de Bruin, Nathanael S. Gray, Jos Jonkers, Jeffrey M. Rosen & Joan S. Brugge. (2009) Fibroblast Growth Factor Receptor 1–Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival. Cancer Research 69:6, pages 2244-2251.
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Yihong Zhang, Paula J. Kaplan-Lefko, Karen Rex, Yajing Yang, Jodi Moriguchi, Tao Osgood, Bethany Mattson, Angela Coxon, Monica Reese, Tae-Seong Kim, Jasmine Lin, April Chen, Teresa L. Burgess & Isabelle Dussault. (2008) Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo . Cancer Research 68:16, pages 6680-6687.
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Cornelia Liedtke, Luca Cardone, Attila Tordai, Kai Yan, Henry L Gomez, Luis J Barajas Figureoa, Rebekah E Hubbard, Vicente Valero, Eduardo A Souchon, W Fraser Symmans, Gabriel N Hortobagyi, Alberto Bardelli & Lajos Pusztai. (2008) PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer. Breast Cancer Research 10:2.
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Anirban MaitraRalph H. Hruban. (2008) Pancreatic Cancer. Annual Review of Pathology: Mechanisms of Disease 3:1, pages 157-188.
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Michael Davies, Sunil Patel & Kevin B. Kim. 2008. Targeted Cancer Therapy. Targeted Cancer Therapy 183 211 .
P J Roberts & C J Der. (2007) Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26:22, pages 3291-3310.
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