Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 2, 2002 - Issue 2
Submit an article Journal homepage
358
Views
95
CrossRef citations to date
0
Altmetric
Drug Evaluation

Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers

John M Embil Infection Control Unit, MS673, 820 Sherbrook St, Health Sciences Centre, Winnipeg, Manitoba R3A 1R9, Canada. [email protected]
&
Mary K Nagai Infection Control Unit, MS673, 820 Sherbrook St, Health Sciences Centre, Winnipeg, Manitoba R3A 1R9, Canada. [email protected]
Pages 211-218 | Published online: 23 Feb 2005

Citations (95)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Jiacong Guo, Cheng Chang & Wei Li. (2017) The role of secreted heat shock protein-90 (Hsp90) in wound healing - how could it shape future therapeutics?. Expert Review of Proteomics 14:8, pages 665-675.
Read now
Gary W. Moore, James C. Maloney, Robert A. Archer, Kerri L. Brown, Katarzyna Mayger, Elaine S. Bromidge & Mitra F. Najafi. (2017) Platelet-rich plasma for tissue regeneration can be stored at room temperature for at least five days. British Journal of Biomedical Science 74:2, pages 71-77.
Read now
Peter Blume, Melinda Bowlby, Brian M Schmidt & Ryan Donegan. (2014) Safety and efficacy of Becaplermin gel in the treatment of diabetic foot ulcers. Chronic Wound Care Management and Research 1, pages 11-14.
Read now
Darrell H Carney & Barbara Olszewska-Pazdrak. (2008) Could rusalatide acetate be the future drug of choice for diabetic foot ulcers and fracture repair?. Expert Opinion on Pharmacotherapy 9:15, pages 2717-2726.
Read now
Nikolaos Papanas & Efstratios Maltezos. (2008) Becaplermin gel in the treatment of diabetic neuropathic foot ulcers. Clinical Interventions in Aging 3:2, pages 233-240.
Read now
Xinhua Lin, Kazuyuki Takahashi, Yi Liu, Alexandrine Derrien & Paul O. Zamora. (2007) A synthetic, bioactive PDGF mimetic with binding to both α-PDGF and β-PDGF receptors. Growth Factors 25:2, pages 87-93.
Read now

Articles from other publishers (89)

Samrat Chauhan, Rishabh Chalotra, Akshay Rathi, Monika Saini, Shweta Deol, Mehak Lard & Sumeet Gupta. (2023) Current Approaches in Healing of Wounds in Diabetes and Diabetic Foot Ulcers. Current Bioactive Compounds 19:3.
Crossref
Marisa Kujawa, Megan O’Meara, Hainan Li, Liping Xu, Sai Pranathi Meda Venkata, Huong Nguyen, Morgan Minjares, Kezhong Zhang & Jie-Mei Wang. (2022) MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-5. Molecular Therapy - Nucleic Acids 29, pages 259-271.
Crossref
Yangbo Xi, Dongping Chen, Zhihui Dong, Hingcheung Lam, Jiading He, Keyi Du, Can Chen, Jun Guo & Jianmin Xiao. (2022) RNA Sequencing of Cardiac in a Rat Model Uncovers Potential Target LncRNA of Diabetic Cardiomyopathy. Frontiers in Genetics 13.
Crossref
Michael Singh, Serhat Akkaya, Mark Preuß, Franziska Rademacher, Mersedeh Tohidnezhad, Yusuke Kubo, Peter Behrendt, Jan-Tobias Weitkamp, Thilo Wedel, Ralph Lucius, Regine Gläser, Jürgen Harder & Andreas Bayer. (2022) Platelet-Released Growth Factors Influence Wound Healing-Associated Genes in Human Keratinocytes and Ex Vivo Skin Explants. International Journal of Molecular Sciences 23:5, pages 2827.
Crossref
Aswathy Ravindran Girija, Sivakumar Balasubramanian & Allison J. Cowin. (2022) Nanomaterials-based Drug Delivery Approaches for Wound Healing. Current Pharmaceutical Design 28:9, pages 711-726.
Crossref
Arash Mohammadi Tofigh & Majid Tajik. (2022) Comparing the standard surgical dressing with dehydrated amnion and platelet-derived growth factor dressings in the healing rate of diabetic foot ulcer: A randomized clinical trial. Diabetes Research and Clinical Practice 185, pages 109775.
Crossref
Seyede Atefe Hosseini, Reyhaneh Shafieian & Fatemeh Alipour. 2022. Biomaterials for Vasculogenesis and Angiogenesis. Biomaterials for Vasculogenesis and Angiogenesis 85 111 .
Jamie L. Burgess, W. Austin Wyant, Beatriz Abdo Abujamra, Robert S. Kirsner & Ivan Jozic. (2021) Diabetic Wound-Healing Science. Medicina 57:10, pages 1072.
Crossref
Xin TangMichelle HaoCheng ChangAyesha BhatiaKathrine O'BrienMei ChenDavid G. ArmstrongWei Li. (2021) Wound Healing Driver Gene and Therapeutic Development: Political and Scientific Hurdles. Advances in Wound Care 10:8, pages 415-435.
Crossref
Tarek Hassan M. Kabil. 2021. Diabetic Foot Ulcer. Diabetic Foot Ulcer 135 147 .
Deepti Singh & Hifzur R. Siddique. 2021. Diabetic Foot Ulcer. Diabetic Foot Ulcer 233 249 .
Ying Yang & Yin Xiao. (2020) Biomaterials Regulating Bone Hematoma for Osteogenesis. Advanced Healthcare Materials 9:23.
Crossref
Atanu Naskar & Kwang-sun Kim. (2020) Recent Advances in Nanomaterial-Based Wound-Healing Therapeutics. Pharmaceutics 12:6, pages 499.
Crossref
Saritha Mohanan, MaryTheresa Sylvia, Udayashankar Carounanidy & RamachandranV Bhat. (2020) Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata. Indian Journal of Dermatology, Venereology and Leprology 86:6, pages 643.
Crossref
Anna Niu, Zhang Zhang, Xiaolin Wang, Jing Wang, Junjie Xu, Xin Su, Xiaopeng Zhang & Wei Chen. (2020) Development of a novel reporter gene assay for platelet-derived growth factor-BB bioactivity. Biologicals 63, pages 68-73.
Crossref
Bin Zhang, Jie Huang & Roger Narayan. 2020. Nanostructured Biomaterials for Regenerative Medicine. Nanostructured Biomaterials for Regenerative Medicine 47 80 .
S. R. Suja, A. L. Aneeshkumar & R. Prakashkumar. 2020. Plant Metabolites: Methods, Applications and Prospects. Plant Metabolites: Methods, Applications and Prospects 553 581 .
Patricio Lau, Stephanie Cruz, Sundeep Keswani & Oluyinka O. Olutoye. 2020. Pediatric Surgery. Pediatric Surgery 73 88 .
Christopher S. Farrar, Geoffrey T. Rouin, Benjamin L. Miller, Carol H. Raeman, Nancie A. Mooney & Denise C. Hocking. (2019) A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release. Cells 8:11, pages 1351.
Crossref
Vadim Lincoln, Xin Tang, Mei Chen & Wei Li. (2019) After Conventional Wisdom Has Failed, What Drives Wound Healing?. European Medical Journal, pages 100-109.
Crossref
Jemma Evans, Giuseppe Infusini, Jacqui Mcgovern, Leila Cuttle, Andrew Webb, Thomas Nebl, Liz Milla, Roy Kimble, Margit Kempf, Christine J. Andrews, David Leavesley & Lois A. Salamonsen. (2018) Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair. The FASEB Journal 33:1, pages 584-605.
Crossref
Vadim Lincoln, Xin Tang, Mei Chen & Wei Li. 2019. Heat Shock Proteins in Signaling Pathways. Heat Shock Proteins in Signaling Pathways 289 315 .
Ayesha Bhatia, Kathryn O’Brien, Jiacong Guo, Vadim Lincoln, Chiaki Kajiwara, Mei Chen, David T. Woodley, Heiichiro Udono & Wei Li. (2018) Extracellular and Non-Chaperone Function of Heat Shock Protein−90α Is Required for Skin Wound Healing. Journal of Investigative Dermatology 138:2, pages 423-433.
Crossref
C.‐H. Heldin, J. Lennartsson & B. Westermark. (2017) Involvement of platelet‐derived growth factor ligands and receptors in tumorigenesis. Journal of Internal Medicine 283:1, pages 16-44.
Crossref
Parisa Goodarzi, Bagher Larijani, Sepideh Alavi-Moghadam, Akram Tayanloo-Beik, Fereshteh Mohamadi-Jahani, Negar Ranjbaran, Moloud Payab, Khadijeh Falahzadeh, Maryamsadat Mousavi & Babak Arjmand. 2018. Cell Biology and Translational Medicine, Volume 4. Cell Biology and Translational Medicine, Volume 4 119 131 .
Zhenchao Tao, Jin Gao, Liting Qian, Yifan Huang, Yan Zhou, Liping Yang, Jian He, Jing Yang, Ru Wang & Yangyang Zhang. (2017) Factors associated with acute oral mucosal reaction induced by radiotherapy in head and neck squamous cell carcinoma. Medicine 96:50, pages e8446.
Crossref
Patrick Y.K. Yue, H.M. Leung, Adela J. Li, Tracy N.C. Chan, T.S. Lum, Y. L. Chung, Y.H. Sung, M.H. Wong, Kelvin S.Y. Leung & Eddy Y. Zeng. (2015) Angiosuppressive properties of marine-derived compounds—a mini review. Environmental Science and Pollution Research 24:10, pages 8990-9001.
Crossref
Suzana Hamdan, Irena Pastar, Stefan Drakulich, Emre Dikici, Marjana Tomic-Canic, Sapna Deo & Sylvia Daunert. (2017) Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications. ACS Central Science 3:3, pages 163-175.
Crossref
Rebecca J. Linger, Esther J. Belikoff, Ying Yan, Fang Li, Holly A. Wantuch, Helen L. Fitzsimons & Maxwell J. Scott. (2016) Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor. BMC Biotechnology 16:1.
Crossref
Ayesha BhatiaKathryn O'BrienMei ChenDavid T. WoodleyWei Li. (2016) Keratinocyte-Secreted Heat Shock Protein-90alpha: Leading Wound Reepithelialization and Closure. Advances in Wound Care 5:4, pages 176-184.
Crossref
Olivia Twu, Suzanne Mednik, Philip Scumpia, Sarah Doaty & Scott Worswick. (2016) Use of Becaplermin for nondiabetic ulcers: pyoderma gangrenosum and calciphylaxis. Dermatologic Therapy 29:2, pages 104-108.
Crossref
Mengmeng Dai, Changming Yu, Ting Fang, Ling Fu, Jing Wang, Jun Zhang, Jun Ren, Junjie Xu, Xiaopeng Zhang & Wei Chen. (2015) Identification and Functional Characterization of Glycosylation of Recombinant Human Platelet-Derived Growth Factor-BB in Pichia pastoris. PLOS ONE 10:12, pages e0145419.
Crossref
Shinjiro Horikawa, Yoko Ishii, Takeru Hamashima, Seiji Yamamoto, Hisashi Mori, Toshihiko Fujimori, Jie Shen, Ran Inoue, Hirofumi Nishizono, Hiroshi Itoh, Masataka Majima, David Abraham, Toshio Miyawaki & Masakiyo Sasahara. (2015) PDGFRα plays a crucial role in connective tissue remodeling. Scientific Reports 5:1.
Crossref
Hong Huang, Wenhui Cui, Wei Qiu, Ming Zhu, Rongshen Zhao, Dengfen Zeng, Chenhui Dong, Xiaohui Wang, Wei Guo, Wei Xing, Xiangyun Li, Lei Li, Yan Tan, Xiaofeng Wu, Lizhao Chen, Xiaobing Fu, Donglin Luo & Xiang Xu. (2015) Impaired wound healing results from the dysfunction of the Akt/mTOR pathway in diabetic rats. Journal of Dermatological Science 79:3, pages 241-251.
Crossref
Kyle J. Miller, David A. Brown, Mohamed M. Ibrahim, Talisha D. Ramchal & Howard Levinson. (2015) MicroRNAs in skin tissue engineering. Advanced Drug Delivery Reviews 88, pages 16-36.
Crossref
Dominik DuscherEvgenios NeofytouVictor W. WongZeshaan N. MaanRobert C. RennertMohammed Inayathullah, Michael JanuszykMelanie RodriguesAndrey V. Malkovskiy, Arnetha J. WhitmoreGraham G. Walmsley, Michael G. GalvezAlexander J. WhittamMichael Brownlee, Jayakumar Rajadas & Geoffrey C. Gurtner. (2014) Transdermal deferoxamine prevents pressure-induced diabetic ulcers. Proceedings of the National Academy of Sciences 112:1, pages 94-99.
Crossref
Ferdous Khan, Masaru Tanaka & Sheikh Rafi Ahmad. (2015) Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices. Journal of Materials Chemistry B 3:42, pages 8224-8249.
Crossref
Thanh Dinh, Shawn Braunagel & Barry I. Rosenblum. (2015) Growth Factors in Wound Healing. Clinics in Podiatric Medicine and Surgery 32:1, pages 109-119.
Crossref
Xiao-hong Zhao, Hai-feng Gu, Zhe-rong Xu, Qin Zhang, Xue-ying Lv, Xiao-jun Zheng & Yun-mei Yang. (2014) Efficacy of topical recombinant human platelet-derived growth factor for treatment of diabetic lower-extremity ulcers: Systematic review and meta-analysis. Metabolism 63:10, pages 1304-1313.
Crossref
Waqar Ul Hassan, Udo Greiser & Wenxin Wang. (2014) Role of adipose-derived stem cells in wound healing. Wound Repair and Regeneration 22:3, pages 313-325.
Crossref
Robert J. Allen Jr.Marc A. Soares, Ilyse D. Haberman, Caroline Szpalski, Jeffrey Schachar, Clarence D. Lin, Phuong D. Nguyen, Pierre B. Saadeh & Stephen M. Warren. (2014) Combination Therapy Accelerates Diabetic Wound Closure. PLoS ONE 9:3, pages e92667.
Crossref
Kanagasabapathy Deepa, Roman N. Rodionov, Norbert Weiss & Madasamy Parani. (2013) Transgenic Expression and Functional Characterization of Human Platelet Derived Growth Factor BB (hPDGF-BB) in Tobacco (Nicotiana tabacum L.). Applied Biochemistry and Biotechnology 171:6, pages 1390-1404.
Crossref
Christopher W. DiGiovanni, Mark Glazebrook, Leo B. Snel, Bill Beasley, Samuel E. Lynch & Gary E. Friedlaender. (2013) A review of the clinical experience with recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Orthopaedic Practice 24:5, pages 476-481.
Crossref
Nicholas A. Richmond, Alejandra C. Vivas & Robert S. Kirsner. (2013) Topical and Biologic Therapies for Diabetic Foot Ulcers. Medical Clinics of North America 97:5, pages 883-898.
Crossref
Katherine Roy & Seth B. Forman. 2013. Comprehensive Dermatologic Drug Therapy. Comprehensive Dermatologic Drug Therapy 629 635.e2 .
Wei Li, Fred Tsen, Divya Sahu, Ayesha Bhatia, Mei Chen, Gabriele Multhoff & David T. Woodley. 2013. 203 235 .
Sandor Szabo, Xiaoming Deng, Tetyana Khomenko, Ganna Tolstanova, Brankica Paunovic, Longchuan Chen, Ximing Xiong & Zsuzsanna Sandor. 2013. Handbook of Biologically Active Peptides. Handbook of Biologically Active Peptides 1172 1181 .
Jeffrey J. Rice, Mikaël M. Martino, Laura De Laporte, Federico Tortelli, Priscilla S. Briquez & Jeffrey A. Hubbell. (2012) Engineering the Regenerative Microenvironment with Biomaterials. Advanced Healthcare Materials 2:1, pages 57-71.
Crossref
Wei Li, Divya Sahu & Fred Tsen. (2012) Secreted heat shock protein-90 (Hsp90) in wound healing and cancer. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:3, pages 730-741.
Crossref
Wei Li, Kathryn O’Brien, David T. Woodley & Mei Chen. 2012. Cellular Trafficking of Cell Stress Proteins in Health and Disease. Cellular Trafficking of Cell Stress Proteins in Health and Disease 259 277 .
Chieh-Fang Cheng, Divya Sahu, Fred Tsen, Zhengwei Zhao, Jianhua Fan, Rosie Kim, Xinyi Wang, Kathryn O’Brien, Yong Li, Yuting Kuang, Mei Chen, David T. Woodley & Wei Li. (2011) A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice. Journal of Clinical Investigation 121:11, pages 4348-4361.
Crossref
Mikaël M. MartinoFederico TortelliMayumi MochizukiStephanie TraubDror Ben-DavidGisela A. KuhnRalph MüllerErella LivneSabine A. EmingJeffrey A. Hubbell. (2011) Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing. Science Translational Medicine 3:100.
Crossref
Ruben Crespo-Diaz, Atta Behfar, Greg W. Butler, Douglas J. Padley, Michael G. Sarr, Jozef Bartunek, Allan B. Dietz & Andre Terzic. (2011) Platelet Lysate Consisting of a Natural Repair Proteome Supports Human Mesenchymal Stem Cell Proliferation and Chromosomal Stability. Cell Transplantation 20:6, pages 797-812.
Crossref
Fa-Ming Chen, Min Zhang & Zhi-Fen Wu. (2010) Toward delivery of multiple growth factors in tissue engineering. Biomaterials 31:24, pages 6279-6308.
Crossref
Tereze Laing, Richard Hanson, Fuan Chan & David Bouchier-Hayes. (2010) Effect of Pravastatin on Experimental Diabetic Wound Healing. Journal of Surgical Research 161:2, pages 336-340.
Crossref
Steven Percival & Keith CuttingKeith Moore. 2010. Microbiology of Wounds. Microbiology of Wounds 151 186 .
Shyam S. Jaiswal, R. P. S. Gambhir, Amit Agrawal & S Harish. (2010) Efficacy of topical recombinant human platelet derived growth factor on wound healing in patients with chronic diabetic lower limb ulcers. Indian Journal of Surgery 72:1, pages 27-31.
Crossref
Qinghua Sun, Eduardo A Silva, Aixia Wang, James C. Fritton, David J. Mooney, Mitchell B. Schaffler, Paul M. Grossman & Sanjay Rajagopalan. (2009) Sustained Release of Multiple Growth Factors from Injectable Polymeric System as a Novel Therapeutic Approach Towards Angiogenesis. Pharmaceutical Research 27:2, pages 264-271.
Crossref
Colonya C. Calhoun, Omel Cardenes, Joseph Ducksworth & Anh D. Le. (2009) Off-Label Use of Becaplermin Gel (Recombinant Platelet-Derived Growth Factor-BB) for Treatment of Mucosal Defects After Corticocancellous Bone Graft: Report of 2 Cases With Review of the Literature. Journal of Oral and Maxillofacial Surgery 67:11, pages 2516-2520.
Crossref
M Jean, F Smaoui, M Lavertu, S Méthot, L Bouhdoud, M D Buschmann & A Merzouki. (2009) Chitosan–plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies. Gene Therapy 16:9, pages 1097-1110.
Crossref
Aleksandra Krajewski, Manish Garg, Mithu De & Rajiv Y. Chandawarkar. (2009) Phagocytosis: Reemerging Roles for a Primitive Function. Plastic and Reconstructive Surgery 123:3, pages 834-847.
Crossref
Haihong Li, Xiaobing Fu, Lei Zhang, Qingjun Huang, Zhigu Wu & Tongzhu Sun. (2008) Research of PDGF-BB Gel on the Wound Healing of Diabetic Rats and Its Pharmacodynamics. Journal of Surgical Research 145:1, pages 41-48.
Crossref
A. Shojaie Fard, M. Esmaelzadeh & B. Larijani. (2007) Assessment and treatment of diabetic foot ulcer. International Journal of Clinical Practice 61:11, pages 1931-1938.
Crossref
Liora Braiman-Wiksman, Inessa Solomonik, Ram Spira & Tamar Tennenbaum. (2016) Novel Insights into Wound Healing Sequence of Events. Toxicologic Pathology 35:6, pages 767-779.
Crossref
John Fisher, Antonios Mikos & Joseph BronzinoA Göpferich & C Becker. 2007. Tissue Engineering. Tissue Engineering 13-1 13-24 .
N. Papanas & E. Maltezos. (2016) Growth Factors in the Treatment of Diabetic Foot Ulcers: New Technologies, Any Promises?. The International Journal of Lower Extremity Wounds 6:1, pages 37-53.
Crossref
Nalini Rao & Benjamin A Lipsky. (2007) Optimising Antimicrobial Therapy in Diabetic Foot Infections. Drugs 67:2, pages 195-214.
Crossref
Reinhard Gruber, Hannjörg Koch, Bruce A. Doll, Florian Tegtmeier, Thomas A. Einhorn & Jeffrey O. Hollinger. (2006) Fracture healing in the elderly patient. Experimental Gerontology 41:11, pages 1080-1093.
Crossref
Leslie I. Gold, Mohammad Rahman, Keith M. Blechman, Matthew R. Greives, Samara Churgin, Joseph Michaels, Matthew J. Callaghan, Nancy L. Cardwell, Alonda C. Pollins, Marek Michalak, John W. Siebert, Jamie P. Levine, Geoffrey C. Gurtner, Lillian B. Nanney, Robert D. Galiano & Caprice L. Cadacio. (2006) Overview of the Role for Calreticulin in the Enhancement of Wound Healing through Multiple Biological Effects. Journal of Investigative Dermatology Symposium Proceedings 11:1, pages 57-65.
Crossref
Stelios T. Andreadis & David J. Geer. (2006) Biomimetic approaches to protein and gene delivery for tissue regeneration. Trends in Biotechnology 24:7, pages 331-337.
Crossref
Benjamin A. Lipsky, Anthony R. Berendt, H Gunner Deery, John M. Embil, Warren S. Joseph, Adolf W. Karchmer, Jack L. LeFrock, Daniel P. Lew, Jon T. Mader, Carl Norden & James S. Tan. (2006) Diagnosis and Treatment of Diabetic Foot Infections. Plastic and Reconstructive Surgery 117:SUPPLEMENT, pages 212S-238S.
Crossref
Olivier Carion, Julien Lefebvre, Guy Dubreucq, Latifa Dahri-Correia, José Correia & Oleg Melnyk. (2006) Polysaccharide Microarrays for Polysaccharide-Platelet-Derived-Growth-Factor Interaction Studies. ChemBioChem 7:5, pages 817-826.
Crossref
Don M. Ranly, Jacquelyn McMillan, Wade F. Krause, Christoph H. Lohmann, Barbara D. Boyan & Zvi Schwartz. 2006. Wiley Encyclopedia of Biomedical Engineering. Wiley Encyclopedia of Biomedical Engineering.
Keren Levanon, Nira Varda-Bloom, Shoshana Greenberger, Iris Barshack, Iris Goldberg, Arie Orenstein, Eyal Breitbart, Aviv Shaish & Dror Harats. (2006) Vascular Wall Maturation and Prolonged Angiogenic Effect by Endothelial-Specific Platelet-Derived Growth Factor Expression. Pathobiology 73:3, pages 149-158.
Crossref
Olivera Stojadinovic, Harold Brem, Constantinos Vouthounis, Brian Lee, John Fallon, Michael Stallcup, Ankit Merchant, Robert D. Galiano & Marjana Tomic-Canic. (2005) Molecular Pathogenesis of Chronic Wounds. The American Journal of Pathology 167:1, pages 59-69.
Crossref
Kouros Izadi & Parham Ganchi. (2005) Chronic Wounds. Clinics in Plastic Surgery 32:2, pages 209-222.
Crossref
Benjamin A. LipskyAnthony R. BerendtH. Gunner DeeryJohn M. EmbilWarren S. JosephAdolf W. KarchmerJack L. LeFrockDaniel P. LewJon T. MaderCarl NordenJames S. Tan. (2005) Diagnosis and Treatment of Diabetic Foot Infections. Journal of the American Podiatric Medical Association 95:2, pages 183-210.
Crossref
Maria I. Morasso & Marjana Tomic-Canic. (2005) Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biology of the Cell 97:3, pages 173-183.
Crossref
Rayaz A. Malik. 2005. Vascular Complications of Diabetes. Vascular Complications of Diabetes 105 112 .
U. Wollina, M. Gruner, A. Koch, E. Köstler, W. Hubl, N.B. Hanson & J. Oshima. (2004) Topical PDGF-BB results in limited healing in a patient with Werner’s syndrome and chronic leg ulcers. Journal of Wound Care 13:10, pages 415-416.
Crossref
Benjamin A. Lipsky, Anthony R. Berendt, H. Gunner Deery, John M. Embil, Warren S. Joseph, Adolf W. Karchmer, Jack L. LeFrock, Daniel P. Lew, Jon T. Mader, Carl Norden & James S. Tan. (2004) Diagnosis and Treatment of Diabetic Foot Infections. Clinical Infectious Diseases 39:7, pages 885-910.
Crossref
Stephen F. Badylak. (2004) Extracellular matrix as a scaffold for tissue engineering in veterinary medicine: Applications to soft tissue healing. Clinical Techniques in Equine Practice 3:2, pages 173-181.
Crossref
Harold Brem, Peter Sheehan & Andrew J.M Boulton. (2004) Protocol for treatment of diabetic foot ulcers. The American Journal of Surgery 187:5, pages S1-S10.
Crossref
Douglas Queen, Heather Orsted, Hiromi Sanada & Geoff Sussman. (2004) A dressing history. International Wound Journal 1:1, pages 59-77.
Crossref
P. Senet. (2004) Bécaplermine gel (Regranex® gel). Annales de Dermatologie et de Vénéréologie 131:4, pages 351-358.
Crossref
Emre Vural. (2004) Surgical reconstruction in patients with cancer of the head and neck. Current Oncology Reports 6:2, pages 133-140.
Crossref
Beat Schwegler. (2003) Fussulzera bei Diabetes mellitus. pharma-kritik 25:11.
Crossref
Tanyarut Boontheekul & David J Mooney. (2003) Protein-based signaling systems in tissue engineering. Current Opinion in Biotechnology 14:5, pages 559-565.
Crossref
SABINE WERNER & RICHARD GROSE. (2003) Regulation of Wound Healing by Growth Factors and Cytokines. Physiological Reviews 83:3, pages 835-870.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.