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Expert Opinion on Biological Therapy Volume 15, 2015 - Issue sup1: Proceedings of the Fourth International Symposium on Thymosins in Health and Disease
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Original Research

Thymosin α1 inserts N terminus into model membranes assuming a helical conformation

Ridvan NepravishtaUniversity of Rome “Tor Vergata”, Department of Chemical Sciences and Technologies, Via della Ricerca Scientifica 1, 00133 Rome, [email protected]
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Walter MandalitiUniversity of Rome “Tor Vergata”, Department of Chemical Sciences and Technologies, Via della Ricerca Scientifica 1, 00133 Rome, [email protected]
,
Tommaso EliseoUniversity of Rome “Tor Vergata”, Department of Chemical Sciences and Technologies, Via della Ricerca Scientifica 1, 00133 Rome, [email protected]
,
Paola Sinibaldi VallebonaUniversity of Rome “Tor Vergata”, Department of Chemical Science and technology, Department of Experimental Medicine and Surgery, Via Montpellier 1, 00133 Rome, Italy
,
Francesca PicaUniversity of Rome “Tor Vergata”, Department of Chemical Science and technology, Department of Experimental Medicine and Surgery, Via Montpellier 1, 00133 Rome, Italy
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Enrico GaraciUniversity of Rome “Tor Vergata”, Department of Chemical Science and technology, Department of Experimental Medicine and Surgery, Via Montpellier 1, 00133 Rome, Italy
&
Maurizio PaciUniversity of Rome “Tor Vergata”, Department of Chemical Sciences and Technologies, Via della Ricerca Scientifica 1, 00133 Rome, [email protected]
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Pages 71-81 | Published online: 02 Feb 2015

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Francesca Pica, Roberta Gaziano, Ida Antonia Casalinuovo, Gabriella Moroni, Cristina Buè, Dolores Limongi, Cartesio D’Agostini, Carlo Tomino, Roberto Perricone, Anna Teresa Palamara, Paola Sinibaldi Vallebona & Enrico Garaci. (2018) Serum thymosin alpha 1 levels in normal and pathological conditions. Expert Opinion on Biological Therapy 18:sup1, pages 13-21.
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Walter Mandaliti, Ridvan Nepravishta, Francesca Pica, Paola Sinibaldi Vallebona, Enrico Garaci & Maurizio Paci. (2018) Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses. Expert Opinion on Biological Therapy 18:sup1, pages 33-42.
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Articles from other publishers (12)

Claudia Matteucci, Ridvan Nepravishta, Ayele Argaw-Denboba, Walter Mandaliti, Alessandro Giovinazzo, Vita Petrone, Emanuela Balestrieri, Paola Sinibaldi-Vallebona, Francesca Pica, Maurizio Paci & Enrico Garaci. (2023) Thymosin α1 interacts with Galectin-1 modulating the β-galactosides affinity and inducing alteration in the biological activity. International Immunopharmacology 118, pages 110113.
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Nana Tao, Xie Xu, Yuyuan Ying, Shiyu Hu, Qingru Sun, Guiyuan Lv & Jianli Gao. (2023) Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application. Molecules 28:8, pages 3539.
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Nicola T. Case, Kwamaa Duah, Brett Larsen, Cassandra J. Wong, Anne-Claude Gingras, Teresa R. O’Meara, Nicole Robbins, Amanda O. Veri, Luke Whitesell & Leah E. Cowen. (2021) The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans. Cell Reports 36:8, pages 109584.
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Haruka Kobayashi, Yue Yu & David E. Volk. 2020. Hormonal Signaling in Biology and Medicine. Hormonal Signaling in Biology and Medicine 311 326 .
Fanwen Wang, Caoying Xu, Renhao Peng, Bin Li, Xutong Shen, Heng Zheng & Xingzhen Lao. (2018) Effect of a C-end rule modification on antitumor activity of thymosin α1. Biochimie 154, pages 99-106.
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Fanwen Wang, Bin Li, Pengcheng Fu, Qingqing Li, Heng Zheng & Xingzhen Lao. (2018) Immunomodulatory and enhanced antitumor activity of a modified thymosin α1 in melanoma and lung cancer. International Journal of Pharmaceutics 547:1-2, pages 611-620.
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Walter Mandaliti, Ridvan Nepravishta, Francesca Pica, Paola Sinibaldi Vallebona, Enrico Garaci & Maurizio Paci. (2017) Thymosin α1 Interacts with Hyaluronic Acid Electrostatically by Its Terminal Sequence LKEKK. Molecules 22:11, pages 1843.
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Claudia Matteucci, Sandro Grelli, Emanuela Balestrieri, Antonella Minutolo, Ayele Argaw-Denboba, Beatrice Macchi, Paola Sinibaldi-Vallebona, Carlo Federico Perno, Antonio Mastino & Enrico Garaci. (2017) Thymosin alpha 1 and HIV-1: recent advances and future perspectives. Future Microbiology 12:2, pages 141-155.
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F Pica, M S Chimenti, R Gaziano, C Buè, I A Casalinuovo, P Triggianese, P Conigliaro, D Di Carlo, V Cordero, G Adorno, A Volpi, R Perricone & E Garaci. (2016) Serum thymosin α 1 levels in patients with chronic inflammatory autoimmune diseases. Clinical and Experimental Immunology 186:1, pages 39-45.
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Walter Mandaliti, Ridvan Nepravishta, Paola Sinibaldi Vallebona, Francesca Pica, Enrico Garaci & Maurizio Paci. (2016) New studies about the insertion mechanism of Thymosin α1 in negative regions of model membranes as starting point of the bioactivity. Amino Acids 48:5, pages 1231-1239.
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Walter Mandaliti, Ridvan Nepravishta, Paola Sinibaldi Vallebona, Francesca Pica, Enrico Garaci & Maurizio Paci. (2016) Thymosin α1 Interacts with Exposed Phosphatidylserine in Membrane Models and in Cells and Uses Serum Albumin as a Carrier. Biochemistry 55:10, pages 1462-1472.
Crossref
K. Hoch & D.E. Volk. 2016. Thymosins. Thymosins 1 24 .

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