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Expert Opinion on Biological Therapy Volume 15, 2015 - Issue sup1: Proceedings of the Fourth International Symposium on Thymosins in Health and Disease
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Original Research

Dual effect of Thymosin α 1 on human monocyte-derived dendritic cell in vitro stimulated with viral and bacterial toll-like receptor agonists

Elena GiacominiIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Martina SeveraIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Melania CrucianiIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Marilena Paola EtnaIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Fabiana RizzoIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Manuela PardiniIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Carolina ScagnolariIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected];Pasteur Institute-Cenci Bolognetti Foundation, Department of Molecular Medicine, Sapienza UniversityRome, Italy
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Enrico GaraciUniversity of Rome Tor Vergata, Department of Experimental Medicine and Surgery, Rome, Italy
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Eliana Marina CocciaIstituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151, Italy+39 06 49903638; +39 06 49903638; [email protected]
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Pages 59-70 | Published online: 22 Jun 2015

Citations (16)

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Xiaoning Wu, Yiwen Shi, Jialing Zhou, Yameng Sun, Hongxin Piao, Wei Jiang, Anlin Ma, Yongpeng Chen, Mingyi Xu, Wen Xie, Jun Cheng, Shibin Xie, Jia Shang, Jilin Cheng, Qing Xie, Huiguo Ding, Xuqing Zhang, Lang Bai, Mingxiang Zhang, Bingqiong Wang, Shuyan Chen, Hong Ma, Xiaojuan Ou, Jidong Jia & Hong You. (2018) Combination of entecavir with thymosin alpha-1 in HBV-related compensated cirrhosis: a prospective multicenter randomized open-label study. Expert Opinion on Biological Therapy 18:sup1, pages 61-69.
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Articles from other publishers (15)

M.S. Espinar-Buitrago, E. Vazquez-Alejo, E. Magro-Lopez, L. Tarancon-Diez, M. Leal & M.A. Muñoz-Fernandez. (2023) Immune modulation via dendritic cells by the effect of Thymosin-alpha-1 on immune synapse in HCMV infection. International Immunopharmacology 125, pages 111103.
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M. S. Espinar-Buitrago, L. Tarancon-Diez, E. Vazquez-Alejo, E. Magro-Lopez, M. Genebat, F. Romero-Candau, M. Leal & M. A. Muñoz-Fernandez. (2023) The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov2. Immunity & Ageing 20:1.
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Daniela Ricci, Marilena Paola Etna, Martina Severa, Stefano Fiore, Fabiana Rizzo, Marco Iannetta, Massimo Andreoni, Stefano Balducci, Paola Stefanelli, Anna Teresa Palamara & Eliana Marina Coccia. (2023) Novel evidence of Thymosin α1 immunomodulatory properties in SARS-CoV-2 infection: Effect on innate inflammatory response in a peripheral blood mononuclear cell-based in vitro model. International Immunopharmacology 117, pages 109996.
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Yiting Wei, Yunpeng Zhang, Pengcheng Li, Chunguang Yan & Lixin Wang. (2023) Thymosin α-1 in cancer therapy: Immunoregulation and potential applications. International Immunopharmacology 117, pages 109744.
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Fadi Shehadeh, Gregorio Benitez, Evangelia K Mylona, Quynh-Lam Tran, Maria Tsikala-Vafea, Eleftheria Atalla, Matthew Kaczynski & Eleftherios Mylonakis. (2023) A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection. The Journal of Infectious Diseases 227:2, pages 226-235.
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Jing Peng, Ming Ni, Dunfeng Du, Yanjun Lu, Juan Song, Weiyong Liu, Na Shen, Xiong Wang, Yaowu Zhu, Bruce A. Vallance, Ziyong Sun & Hong Bing Yu. (2021) Successful treatment of a kidney transplant patient with COVID-19 and late-onset Pneumocystis jirovecii pneumonia. Annals of Clinical Microbiology and Antimicrobials 20:1.
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Meiyu Chen, Yu Jiang, Xiaohui Cai, Xuzhang Lu & Hongying Chao. (2021) Combination of Gemcitabine and Thymosin alpha 1 exhibit a better anti-tumor effect on nasal natural killer/T-cell lymphoma. International Immunopharmacology 98, pages 107829.
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Jiao Liu, Yanfei Shen, Zhenliang Wen, Qianghong Xu, Zhixiong Wu, Huibin Feng, Zhongyi Li, Xuan Dong, Sisi Huang, Jun Guo, Lidi Zhang, Yizhu Chen, Wenzhe Li, Wei Zhu, Hangxiang Du, Yongan Liu, Tao Wang, Limin Chen, Jean-Louis Teboul, Djillali Annane & Dechang Chen. (2021) Efficacy of Thymosin Alpha 1 in the Treatment of COVID-19: A Multicenter Cohort Study. Frontiers in Immunology 12.
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Melissa Bersanelli, Diana Giannarelli, Alessandro Leonetti, Sebastiano Buti, Marcello Tiseo, Antonio Nouvenne, Andrea Ticinesi, Tiziana Meschi, Giuseppe Procopio & Riccardo Danielli. (2021) The right immune-modulation at the right time: thymosin α1 for prevention of severe COVID-19 in cancer patients. Future Oncology 17:9, pages 1097-1104.
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Ming Wu, Jing-jing Ji, Li Zhong, Zi-yun Shao, Qi-feng Xie, Zhe-ying Liu, Cong-lin Wang, Lei Su, Yong-wen Feng, Zhi-feng Liu & Yong-ming Yao. (2020) Thymosin α1 therapy in critically ill patients with COVID-19: A multicenter retrospective cohort study. International Immunopharmacology 88, pages 106873.
Crossref
Martina Severa, Jing Zhang, Elena Giacomini, Fabiana Rizzo, Marilena Paola Etna, Melania Cruciani, Enrico Garaci, Michael Chopp & Eliana Marina Coccia. (2019) Thymosins in multiple sclerosis and its experimental models: moving from basic to clinical application. Multiple Sclerosis and Related Disorders 27, pages 52-60.
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Yu-Ming Wang, Ke Li, Xiao-Guang Dou, Han Bai, Xi-Ping Zhao, Xiong Ma, Lan-Juan Li, Zhi-Shui Chen & Yuan-Cheng Huang. 2019. Acute Exacerbation of Chronic Hepatitis B. Acute Exacerbation of Chronic Hepatitis B 273 370 .
Roger Davies, Kieran O’Dea & Anthony Gordon. (2018) Immune therapy in sepsis: Are we ready to try again?. Journal of the Intensive Care Society 19:4, pages 326-344.
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Elena Giacomini, Fabiana Rizzo, Marilena P Etna, Melania Cruciani, Rosella Mechelli, Maria Chiara Buscarinu, Francesca Pica, Cartesio D’Agostini, Marco Salvetti, Eliana M Coccia & Martina Severa. (2017) Thymosin-α1 expands deficient IL-10-producing regulatory B cell subsets in relapsing–remitting multiple sclerosis patients. Multiple Sclerosis Journal 24:2, pages 127-139.
Crossref
Fang Liu, Hong-Mei Wang, Tiansheng Wang, Ya-Mei Zhang & Xi Zhu. (2016) The efficacy of thymosin α1 as immunomodulatory treatment for sepsis: a systematic review of randomized controlled trials. BMC Infectious Diseases 16:1.
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