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Editorial

Emerging drugs for preeclampsia – the endothelium as a target

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Esmee C. M. Kooijmans, Helena J. H. van der Pal, Maxime C. F. Pilon, Saskia M. F. Pluijm, Margriet van der Heiden-van der Loo, Leontien C. M. Kremer, Dorine Bresters, Eline van Dulmen-den Broeder, Marry M. van den Heuvel-Eibrink, Jacqueline J. Loonen, Marloes Louwerens, Sebastian J. C. Neggers, Hanneke M. van Santen, Wim J. E. Tissing, Andrica C. H. de Vries, Gertjan J. L. Kaspers, Margreet A. Veening & Arend Bökenkamp. (2022) Shrunken pore syndrome in childhood cancer survivors treated with potentially nephrotoxic therapy. Scandinavian Journal of Clinical and Laboratory Investigation 82:7-8, pages 541-548.
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Araceli Jarquin Campos, Lorenz Risch, Marc Baumann, Mette-Triin Purde, Sebastian Neuber, Harald Renz, Beatrice Mosimann, Luigi Raio, Markus Mohaupt, Daniel Surbek & Martin Risch. (2019) Shrunken pore syndrome, preeclampsia, and markers of NO metabolism in pregnant women during the first trimester. Scandinavian Journal of Clinical and Laboratory Investigation 79:1-2, pages 91-98.
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Marcelo R. Luizon, Daniela A. Pereira, Izabela Mamede, Carla S. Ceron, Ricardo C. Cavalli, Ana C. Palei & Valeria C. Sandrim. (2023) Antihypertensive therapy responsiveness and adverse outcomes in preeclampsia: insights into molecular mechanisms underlying cardiovascular and renal complications. Frontiers in Pharmacology 14.
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Xiaobo Liu, Jiajia Li, Wenjun Wang, Xue Ren & Ji-Fan Hu. (2023) Therapeutic restoration of female reproductive and endocrine dysfunction using stem cells. Life Sciences 322, pages 121658.
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Hannah R. Turbeville & Jennifer M. Sasser. (2020) Preeclampsia beyond pregnancy: long-term consequences for mother and child. American Journal of Physiology-Renal Physiology 318:6, pages F1315-F1326.
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Laura E. Coats, Gwendolyn K. Davis, Ashley D. Newsome, Norma B. Ojeda & Barbara T. Alexander. (2019) Low Birth Weight, Blood Pressure and Renal Susceptibility. Current Hypertension Reports 21:8.
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Hannah R. TurbevilleErin B. TaylorMichael R. GarrettSean P. DidionMichael J. RyanJennifer M. Sasser. (2019) Superimposed Preeclampsia Exacerbates Postpartum Renal Injury Despite Lack of Long-Term Blood Pressure Difference in the Dahl Salt-Sensitive Rat. Hypertension 73:3, pages 650-658.
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Asmaa A. ElMonier, Noha A. El-Boghdady, Mohamed A. Abdelaziz & Amira A. Shaheen. (2019) Association between endoglin/transforming growth factor beta receptors 1, 2 gene polymorphisms and the level of soluble endoglin with preeclampsia in Egyptian women. Archives of Biochemistry and Biophysics 662, pages 7-14.
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Marcelo R Luizon, Daniela A Pereira & Jose E Tanus-Santos. (2018) Pharmacogenetic relevance of endothelial nitric oxide synthase polymorphisms and gene interactions. Pharmacogenomics 19:18, pages 1423-1435.
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Anne Brandolt Larré, Fernando Sontag, Débora Montenegro Pasin, Nathália Paludo, Rayssa Ruszkowski do Amaral, Bartira Ercília Pinheiro da Costa & Carlos Eduardo Poli-de-Figueiredo. (2018) Phosphodiesterase Inhibition in the Treatment of Preeclampsia: What Is New?. Current Hypertension Reports 20:10.
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Patricia M. Witcher. (2018) Preeclampsia: Acute Complications and Management Priorities. AACN Advanced Critical Care 29:3, pages 316-326.
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Enrique Esteve-Valverde, Raquel Ferrer-Oliveras, Natàlia Gil-Aliberas, Antònia Baraldès-Farré, Elisa Llurba & Jaume Alijotas-Reig. (2018) Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review. Obstetrical & Gynecological Survey 73:1, pages 40-55.
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Styliani Goulopoulou. (2017) Maternal Vascular Physiology in Preeclampsia. Hypertension 70:6, pages 1066-1073.
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M R Luizon, A C T Palei, V A Belo, L M Amaral, R Lacchini, G Duarte, R C Cavalli, V C Sandrim & J E Tanus-Santos. (2016) Gene–gene interactions in the NAMPT pathway, plasma visfatin/NAMPT levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy. The Pharmacogenomics Journal 17:5, pages 427-434.
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Anne Brandolt Larré, Aline Parisotto, Bruna Fagundes Rockenbach, Débora Montenegro Pasin, Cláudia Capellari, Daniele Cristovão Escouto, Bartira Ercília Pinheiro da Costa & Carlos Eduardo Poli-de-Figueiredo. (2017) Phosphodiesterases and preeclampsia. Medical Hypotheses 108, pages 94-100.
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Jaume Alijotas-Reig, Enrique Esteve-Valverde, Raquel Ferrer-Oliveras, Elisa Llurba & Josep Maria Gris. (2017) Tumor Necrosis Factor-Alpha and Pregnancy: Focus on Biologics. An Updated and Comprehensive Review. Clinical Reviews in Allergy & Immunology 53:1, pages 40-53.
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Nerolen Soobryan, Saravanakumar Murugesan, Wendy Phoswa, Prem Gathiram, Jagidesa Moodley & Irene Mackraj. (2017) The effects of sildenafil citrate on uterine angiogenic status and serum inflammatory markers in an L-NAME rat model of pre-eclampsia. European Journal of Pharmacology 795, pages 101-107.
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Crystal A. WestJennifer M. Sasser & Chris Baylis. (2016) The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone system. American Journal of Physiology-Renal Physiology 311:6, pages F1125-F1134.
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Kirk P. Conrad. (2016) G-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and prevention. Human Reproduction Update 22:5, pages 647-664.
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Anton H. van den MeirackerA.H. Jan Danser. (2016) Mechanisms of Hypertension and Renal Injury During Vascular Endothelial Growth Factor Signaling Inhibition. Hypertension 68:1, pages 17-23.
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S. Ananth Karumanchi. (2016) Angiogenic Factors in Preeclampsia. Hypertension 67:6, pages 1072-1079.
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Radko Komers & Horacio Plotkin. (2016) Dual inhibition of renin-angiotensin-aldosterone system and endothelin-1 in treatment of chronic kidney disease. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 310:10, pages R877-R884.
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