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Expert Opinion on Therapeutic Targets Volume 11, 2007 - Issue 12
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Review

Targeting platelets for prevention and treatment of cardiovascular disease

Todd A Duhamel University of Manitoba, Institute of Cardiovascular Sciences, St Boniface General Hospital Research Center, Department of Physiology, Faculty of Medicine, 351 Tache Avenue, Winnipeg, Manitoba, R2H 2A6, Canada +1 204 235 3417; +1 204 233 6723; [email protected]
, PhD,
Yan-Jun Xu University of Manitoba, Institute of Cardiovascular Sciences, St Boniface General Hospital Research Center, Department of Physiology, Faculty of Medicine, 351 Tache Avenue, Winnipeg, Manitoba, R2H 2A6, Canada +1 204 235 3417; +1 204 233 6723; [email protected]
, MD PhD,
Amarjit S Arneja University of Manitoba, Institute of Cardiovascular Sciences, St Boniface General Hospital Research Center, Department of Internal Medicine, Faculty of Medicine, Winnipeg, Canada
, MD &
Naranjan S Dhalla University of Manitoba, Institute of Cardiovascular Sciences, St Boniface General Hospital Research Center, Department of Physiology, Faculty of Medicine, 351 Tache Avenue, Winnipeg, Manitoba, R2H 2A6, Canada +1 204 235 3417; +1 204 233 6723; [email protected]
, PhD MD DSc
Pages 1523-1533 | Published online: 18 Nov 2007

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Mohita Shrivastava & S Vivekanandhan. (2011) An Insight into Ultrastructural and Morphological Alterations of Platelets in Neurodegenerative Diseases. Ultrastructural Pathology 35:3, pages 110-116.
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Kiran D. K. Ahuja, Murray J. Adams, Iain K. Robertson & Madeleine J. Ball. (2009) Acute effect of a high-carbohydrate low-fat meal on platelet aggregation. Platelets 20:8, pages 606-609.
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Articles from other publishers (17)

Agnese Barin, Ranjit K. Das, Nasser E. Bastani, Per Ole Iversen & Asim K. Duttaroy. (2023) Extracts of tamarillo, horned melon, and raspberry, but not extract of pear, inhibit human blood platelet aggregation: Investigating the underlying factors for their differential mechanisms. Journal of Functional Foods 110, pages 105847.
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Shengnan Han, Longhui Cai, Peipei Chen & Weihong Kuang. (2023) A study of the correlation between stroke and gut microbiota over the last 20years: a bibliometric analysis. Frontiers in Microbiology 14.
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Olga Zharkova, Maryam F. Salamah, Maria V. Babak, Elanchezhian Rajan, Lina H. K. Lim, Frans Andrade, Cristiane D. Gil, Sonia M. Oliani, Leonardo A. Moraes & Sakthivel Vaiyapuri. (2023) Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets. International Journal of Molecular Sciences 24:4, pages 3424.
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Huilian Chen, Shenghao Zhang, Hui Wang, Li Bao, Wei Wu & Ruomei Qi. (2022) Fruitflow inhibits platelet function by suppressing Akt/GSK3β, Syk/PLCγ2 and p38 MAPK phosphorylation in collagen-stimulated platelets. BMC Complementary Medicine and Therapies 22:1.
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Asim K. Duttaroy. (2021) Role of Gut Microbiota and Their Metabolites on Atherosclerosis, Hypertension and Human Blood Platelet Function: A Review. Nutrients 13:1, pages 144.
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Asim K. Duttaroy. 2021. Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease. Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease 295 309 .
Asim K. Duttaroy. 2021. Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease. Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease 103 113 .
Maryam F. Salamah, Divyashree Ravishankar, Rajendran Vaiyapuri, Leonardo A. Moraes, Ketan Patel, Mauro Perretti, Jonathan M. Gibbins & Sakthivel Vaiyapuri. (2019) The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis 17:7, pages 1120-1133.
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Asim K. Duttaroy. 2018. Nutraceuticals and Human Blood Platelet Function. Nutraceuticals and Human Blood Platelet Function 1 27 .
Gailing Chen, Kevin P. Bliden, Rahul Chaudhary, Fang Liu, Himabindu Kaza, Eliano P. Navarese, Udaya S. Tantry & Paul A. Gurbel. (2017) Central aortic pulse pressure, thrombogenicity and cardiovascular risk. Journal of Thrombosis and Thrombolysis 44:2, pages 223-233.
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N O'Kennedy, L Crosbie, H-J Song, X Zhang, G Horgan & A K Duttaroy. (2016) A randomised controlled trial comparing a dietary antiplatelet, the water-soluble tomato extract Fruitflow, with 75 mg aspirin in healthy subjects. European Journal of Clinical Nutrition 71:6, pages 723-730.
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Niamh O’Kennedy, Daniel Raederstorff & Asim K. Duttaroy. (2016) Fruitflow®: the first European Food Safety Authority-approved natural cardio-protective functional ingredient. European Journal of Nutrition 56:2, pages 461-482.
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Yan-Jun Xu, Paramjit S. Tappia, Nirankar S. Neki & Naranjan S. Dhalla. (2013) Prevention of diabetes-induced cardiovascular complications upon treatment with antioxidants. Heart Failure Reviews 19:1, pages 113-121.
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Yan-Jun Xu, Ming Zhang, Lei Ji, Vijayan Elimban, Li Chen & Naranjan S. Dhalla. (2012) Suppression of high lipid diet induced by atherosclerosis sarpogrelate. Journal of Cellular and Molecular Medicine 16:10, pages 2394-2400.
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Martha Phelan & David Kerins. (2011) The potential role of milk-derived peptides in cardiovascular disease. Food & Function 2:3-4, pages 153.
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Yan-Jun Xu, Meera Kaur, Reshvinder S. Dhillon, Paramjit S. Tappia & Naranjan S. Dhalla. (2011) Health benefits of sea buckthorn for the prevention of cardiovascular diseases. Journal of Functional Foods 3:1, pages 2-12.
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Cristina Ribas Fürstenau, Danielle da Silva Trentin, Agnes Nogueira Gossenheimer, Denise Barbosa Ramos, Emerson André Casali, Maria Luiza Morais Barreto-Chaves & João José Freitas Sarkis. (2008) Ectonucleotidase activities are altered in serum and platelets of l-NAME-treated rats. Blood Cells, Molecules, and Diseases 41:2, pages 223-229.
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