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Expert Opinion on Therapeutic Targets Volume 11, 2007 - Issue 12
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Review

Targeting apoptosis in solid tumors: the role of bortezomib from preclinical to clinical evidence

Antonio Russo Universita' di Palermo, Section of Medical Oncology, Department of Surgical and Oncological Sciences, Italy
,
Maria E Fratto University Campus Bio-Medico, Medical Oncology, Via Emilio Longoni, 81, 00155 Rome, Italy+39 06 22541739; +39 06 22541520; [email protected]
,
Viviana Bazan Universita' di Palermo, Section of Medical Oncology, Department of Surgical and Oncological Sciences, Italy
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Valentina Schiró Universita' di Palermo, Section of Medical Oncology, Department of Surgical and Oncological Sciences, Italy
,
Valentina Agnese Universita' di Palermo, Section of Medical Oncology, Department of Surgical and Oncological Sciences, Italy
,
Giuseppe Cicero Universita' di Palermo, Section of Medical Oncology, Department of Surgical and Oncological Sciences, Italy
,
Bruno Vincenzi University Campus Bio-Medico, Medical Oncology, Via Emilio Longoni, 81, 00155 Rome, Italy+39 06 22541739; +39 06 22541520; [email protected]
,
Giuseppe Tonini University Campus Bio-Medico, Medical Oncology, Via Emilio Longoni, 81, 00155 Rome, Italy+39 06 22541739; +39 06 22541520; [email protected]
&
Daniele Santini University Campus Bio-Medico, Medical Oncology, Via Emilio Longoni, 81, 00155 Rome, Italy+39 06 22541739; +39 06 22541520; [email protected]
, MD PhD show all
Pages 1571-1586 | Published online: 18 Nov 2007

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Yong Fang, Yi Hu, Peng Wu, Beibei Wang, Yuan Tian, Xi Xia, Qinghua Zhang, Tong Chen, Xuefeng Jiang, Quanfu Ma, Gang Xu, Shixuan Wang, Jianfeng Zhou, Ding Ma & Li Meng. (2011) Synergistic Efficacy in Human Ovarian Cancer Cells by Histone Deacetylase Inhibitor TSA and Proteasome Inhibitor PS-341. Cancer Investigation 29:4, pages 247-252.
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Articles from other publishers (10)

Anita K. Luu, Mia Cadieux, Mackenzie Wong, Rachel Macdonald, Robert Jones, Dongsic Choi, Michelle Oblak, Brigitte Brisson, Scott Sauer, James Chafitz, David Warshawsky, Geoffrey A. Wood & Alicia M. Viloria-Petit. (2022) Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle. International Journal of Molecular Sciences 23:6, pages 3256.
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Xin Jin, Yong Fang, Yi Hu, Jing Chen, Wei Liu, Gang Chen, Mei Gong, Peng Wu, Tao Zhu, Shixuan Wang, Jianfeng Zhou, Hui Wang, Ding Ma & Kezhen Li. (2017) Synergistic activity of the histone deacetylase inhibitor trichostatin A and the proteasome inhibitor PS-341 against taxane-resistant ovarian cancer cell lines. Oncology Letters 13:6, pages 4619-4626.
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Kyle R. Cron, Kaya Zhu, Deepa S. Kushwaha, Grace Hsieh, Dmitry Merzon, Jonathan Rameseder, Clark C. Chen, Alan D. D’Andrea & David Kozono. (2013) Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer. PLoS ONE 8:9, pages e73710.
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Myoung W. Lee, Dae S. Kim, Joo H. Lee, Bum S. Lee, Soo H. Lee, Hye L. Jung, Ki W. Sung, Heung T. Kim, Keon H. Yoo & Hong H. Koo. (2011) Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration. Cancer Science 102:10, pages 1822-1828.
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Mingxiang Liao, Ping Kang, Bernard P. Murray & Maria Almira Correia. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development 363 406 .
María Cortes-Sempere, Sharmila Chattopadhyay, Ana Rovira, Vanessa Rodriguez-Fanjul, Cristobal Belda-Iniesta, Marian Tapia, Paloma Cejas, Rosario Machado-Pinilla, Cristina Manguan-García, Isabel Sánchez-Pérez, Manuel Nistal, Carmen Moratilla, Javier de Castro-Carpeño, Manuel Gonzalez-Barón, Joan Albanell & Rosario Perona. (2009) MKP1 repression is required for the chemosensitizing effects of NF-κB and PI3K inhibitors to cisplatin in non-small cell lung cancer. Cancer Letters 286:2, pages 206-216.
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Julia M. Huber, Andrea Tagwerker, Dorothea Heininger, Gert Mayer, Alexander R. Rosenkranz & Kathrin Eller. (2009) The proteasome inhibitor Bortezomib aggravates renal ischemia-reperfusion injury. American Journal of Physiology-Renal Physiology 297:2, pages F451-F460.
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Jarmila Králová, Tomáš Bříza, Irena Moserová, Bohumil Dolenský, Petr Vašek, Pavla Poučková, Zdeněk Kejík, Robert Kaplánek, Pavel Martásek, Michal Dvořák & Vladimír Král. (2008) Glycol Porphyrin Derivatives as Potent Photodynamic Inducers of Apoptosis in Tumor Cells. Journal of Medicinal Chemistry 51:19, pages 5964-5973.
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Zhong Chen, Justin L. Ricker, Pramit S. Malhotra, Liesl Nottingham, Lorena Bagain, Tin Lap Lee, Ning T. Yeh & Carter Van Waes. (2008) Differential bortezomib sensitivity in head and neck cancer lines corresponds to proteasome, nuclear factor-κB and activator protein-1 related mechanisms. Molecular Cancer Therapeutics 7:7, pages 1949-1960.
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Daniele Santini, Bruno Vincenzi & Giuseppe Tonini. (2008) Updated follow-up of patients treated with bortezomib for relapsed multiple myeloma. Nature Clinical Practice Oncology 5:6, pages 304-305.
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