728
Views
21
CrossRef citations to date
0
Altmetric
Reviews

IL-21 as a therapeutic target in inflammatory disorders

, PhD, , PhD, , PhD, , MD & , MD PhD

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Vincenzo Dinallo, Davide Di Fusco, Roberta Izzo & Giovanni Monteleone. (2016) Therapy implications for the role of IL-21 in lupus. Expert Review of Clinical Immunology 12:5, pages 487-488.
Read now

Articles from other publishers (20)

Xuyang Zhao, Lei Zhang, Nan Wu, Yuhang Liu, Jiayuan Xie, Lian Su, Qingsong Zhu, Bruno Hamish Unger, Fatima Altaf, Yuhang Hu, Weidong Ye, Zhixian Qiao, Yingyin Cheng, Wanting Zhang, Yaping Wang & Xiao-Qin Xia. (2024) Gallic acid acts as an anti-inflammatory agent via PPARγ-mediated immunomodulation and antioxidation in fish gut-liver axis. Aquaculture 578, pages 740142.
Crossref
Yue Yin, Jian Wan, Jingmin Yu & Kaichun Wu. (2023) Molecular Pathogenesis of Colitis-associated Colorectal Cancer: Immunity, Genetics, and Intestinal Microecology. Inflammatory Bowel Diseases.
Crossref
Yijie Song, Man Yuan, Yu Xu & Hongxi Xu. (2022) Tackling Inflammatory Bowel Diseases: Targeting Proinflammatory Cytokines and Lymphocyte Homing. Pharmaceuticals 15:9, pages 1080.
Crossref
Jiajia Zeng, Yueyue Xu, Lu Tan, Xiaoyu Zha, Shuaini Yang, Hong Zhang, Yuqing Tuo, Ruoyuan Sun, Wenhao Niu, Gaoju Pang, Lida Sun & Hong Bai. (2022) IL-21/IL-21R Regulates the Neutrophil-Mediated Pathologic Immune Response during Chlamydial Respiratory Infection. Mediators of Inflammation 2022, pages 1-14.
Crossref
Snehali Majumder, Uday Nagesh Shivaji, Rangarajan Kasturi, Alben Sigamani, Subrata Ghosh & Marietta Iacucci. (2022) Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives. World Journal of Gastrointestinal Oncology 14:3, pages 547-567.
Crossref
Shi-quan Zhu, Bian-hua Zhou, Pan-pan Tan, Jun Chai, Ya-ming Yu & Hong-wei Wang. (2020) Based on G-Series Mouse TH17 Array Study the Effect of Fluoride on C2C12 Cells Cytokines Expression. Biological Trace Element Research 199:9, pages 3402-3410.
Crossref
Pedro A. Ruiz Castro, Ulrike Kogel, Giuseppe Lo Sasso, Blaine W. Phillips, Alain Sewer, Bjorn Titz, Llenalia Garcia, Athanasios Kondylis, Emmanuel Guedj, Dariusz Peric, David Bornand, Remi Dulize, Celine Merg, Maica Corciulo, Nikolai V. Ivanov, Manuel C. Peitsch & Julia Hoeng. (2020) Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis. Journal of Inflammation 17:1.
Crossref
Anying Zhang, Xiaoyu Jian, Dan Wang, Jingqi Ren, Xinyan Wang & Hong Zhou. (2020) Characterization and bioactivity of grass carp (Ctenopharyngodon idella) interleukin-21: Inducible production and involvement in inflammatory regulation. Fish & Shellfish Immunology 99, pages 19-26.
Crossref
Itzel Viridiana Reyes-Pérez, Pedro Ernesto Sánchez-Hernández, José Francisco Muñoz-Valle, Gloria Esther Martínez-Bonilla, Trinidad García-Iglesias, Verónica González-Díaz, Samuel García-Arellano, Sergio Cerpa-Cruz, Julissa Polanco-Cruz & María Guadalupe Ramírez-Dueñas. (2019) Cytokines (IL-15, IL-21, and IFN-γ) in rheumatoid arthritis: association with positivity to autoantibodies (RF, anti-CCP, anti-MCV, and anti-PADI4) and clinical activity. Clinical Rheumatology 38:11, pages 3061-3071.
Crossref
Nicole M. van Besouw, Lin Yan, Ronella de Kuiper, Mariska Klepper, Derek Reijerkerk, Marjolein Dieterich, Dave L. Roelen, Frans H. J. Claas, Marian C. Clahsen-van Groningen, Dennis A. Hesselink & Carla C. Baan. (2019) The Number of Donor-Specific IL-21 Producing Cells Before and After Transplantation Predicts Kidney Graft Rejection. Frontiers in Immunology 10.
Crossref
Kejing Wang, Shuang Wen, Jiao Jiao, Tingting Tang, Xin Zhao, Min Zhang, Bingjie Lv, Yuzhi Lu, Xingdi Zhou, Jingyong Li, Shaofang Nie, Yuhua Liao, Qing Wang, Xin Tu, Ziad Mallat, Ni Xia & Xiang Cheng. (2018) IL-21 promotes myocardial ischaemia/reperfusion injury through the modulation of neutrophil infiltration. British Journal of Pharmacology 175:8, pages 1329-1343.
Crossref
Ya-Qin Tan, Qing Li, Jing Zhang, Ge-Fei Du, Rui Lu & Gang Zhou. (2017) Increased circulating CXCR5 + CD4 + T follicular helper-like cells in oral lichen planus . Journal of Oral Pathology & Medicine 46:9, pages 803-809.
Crossref
Shruti Chaturvedi, Pallav BhatnagarChristopher J. BeanMartin H. SteinbergJaqueline N. MiltonJames F. Casella, Emily Barron-Casella, Dan E. ArkingMichael R. DeBaun. (2017) Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia. Blood 130:5, pages 686-688.
Crossref
Kim Ohl, Anastasia Wiener, Ralph Lippe, Angela Schippers, Carolin Zorn, Johannes Roth, Norbert Wagner & Klaus Tenbrock. (2016) CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro. Frontiers in Immunology 7.
Crossref
Rui Xing, Yingjian Zhang, Changhong Li, Lin Sun, Lin Yang, Jinxia Zhao & Xiangyuan Liu. (2016) Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL. International Journal of Molecular Medicine 38:4, pages 1125-1134.
Crossref
Luca Semerano, Emeline Minichiello, Natacha Bessis & Marie-Christophe Boissier. (2016) Novel Immunotherapeutic Avenues for Rheumatoid Arthritis. Trends in Molecular Medicine 22:3, pages 214-229.
Crossref
Warren J. Leonard & Chi-Keung Wan. (2016) IL-21 Signaling in Immunity. F1000Research 5, pages 224.
Crossref
Iain B. McInnes, Christopher D. Buckley & John D. Isaacs. (2015) Cytokines in rheumatoid arthritis — shaping the immunological landscape. Nature Reviews Rheumatology 12:1, pages 63-68.
Crossref
Stuart G Tangye. (2015) Advances in IL-21 biology—enhancing our understanding of human disease. Current Opinion in Immunology 34, pages 107-115.
Crossref
Michela Croce, Valentina Rigo & Silvano Ferrini. (2015) IL-21: A Pleiotropic Cytokine with Potential Applications in Oncology. Journal of Immunology Research 2015, pages 1-15.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.