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Volume 18, Issue 11

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 18, Issue 11 (2014)

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Expert Opinion on Therapeutic Targets, Volume 18, Issue 11 (2014)

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Editorial

Therapeutic potential of targeting glucose metabolism in glioma stem cells

Ichiro Nakano MD PhD

Pages: 1233-1236

Published online: 31 Jul 2014

AbstractforTherapeutic potential of targeting glucose metabolism in glioma stem cells | Full Text | References | PDF (217 KB)

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Free Access

Original Research

Article

Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells

Kimberley Joanne Hatfield, Håkon Reikvam & Øystein Bruserud MD PhD

Pages: 1237-1251

Published online: 09 Sep 2014

AbstractforIdentification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells | Full Text | References | PDF (839.9 KB) | Supplemental

399 Views
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Article

Advancing therapeutic discovery through phenotypic screening of the extracellular proteome using hydrodynamic intravascular injection

Helene Baribault, Jiangwen Z Majeti, Hongfei Ge, Jinghong Wang, Yumei Xiong, Jonitha Gardner, Li Yang, Jamila Gupte, Yan Gong, Zheng Pan, Gene Cutler, Paul Kassner, Hua Tu, Bei Shan, Xinle Wu & Yang Li

Pages: 1253-1264

Published online: 07 Oct 2014

AbstractforAdvancing therapeutic discovery through phenotypic screening of the extracellular proteome using hydrodynamic intravascular injection | Full Text | References | PDF (787 KB)

223 Views
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Reviews

Review Article

The potential to target CCL5/CCR5 in breast cancer

Marco Velasco-Velázquez PhD, Wendy Xolalpa PhD & Richard G Pestell MD PhD

Pages: 1265-1275

Published online: 26 Sep 2014

AbstractforThe potential to target CCL5/CCR5 in breast cancer | Full Text | References | PDF (568.5 KB)

1306 Views
66 CrossRef citations
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Review Article

The role of pancreatic and duodenal homeobox 1 as a therapeutic target in pancreatic cancer

Volker Fendrich MD & Matthias Lauth

Pages: 1277-1283

Published online: 31 Jul 2014

AbstractforThe role of pancreatic and duodenal homeobox 1 as a therapeutic target in pancreatic cancer | Full Text | References | PDF (319.8 KB)

151 Views
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Review Article

Targeting 5-lipoxygenase-activating protein in asthma and chronic obstructive pulmonary disease

Sabina Antonela Antoniu MD PhD

Pages: 1285-1292

Published online: 12 Sep 2014

AbstractforTargeting 5-lipoxygenase-activating protein in asthma and chronic obstructive pulmonary disease | Full Text | References | PDF (204.8 KB)

345 Views
12 CrossRef citations
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Review Article

Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington’s disease

Fabiola M Ribeiro, Alison Hamilton, Juliana G Doria, Isabella M Guimaraes, Sean P Cregan & Stephen SG Ferguson

Pages: 1293-1304

Published online: 14 Aug 2014

AbstractforMetabotropic glutamate receptor 5 as a potential therapeutic target in Huntington’s disease | Full Text | References | PDF (457.1 KB)

551 Views
19 CrossRef citations
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Review Article

The role of fibroblast growth factor 21 in the pathogenesis of liver disease: a novel predictor and therapeutic target

Wen-Yue Liu, Sha Huang, Ke-Qing Shi, Chen-Chen Zhao, Li-Li Chen, Martin Braddock, Yong-Ping Chen, Wen-Ke Feng & Ming-Hua Zheng MD PhD

Pages: 1305-1313

Published online: 31 Jul 2014

AbstractforThe role of fibroblast growth factor 21 in the pathogenesis of liver disease: a novel predictor and therapeutic target | Full Text | References | PDF (381.7 KB)

655 Views
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Review Article

Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy

Heinrich Kovar PhD

Pages: 1315-1328

Published online: 27 Aug 2014

AbstractforBlocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy | Full Text | References | PDF (329.9 KB)

1018 Views
50 CrossRef citations
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Review Article

IL-21 as a therapeutic target in inflammatory disorders

Davide Di Fusco PhD, Roberta Izzo PhD, Michele M Figliuzzi PhD, Francesco Pallone MD & Giovanni Monteleone MD PhD

Pages: 1329-1338

Published online: 27 Aug 2014

AbstractforIL-21 as a therapeutic target in inflammatory disorders | Full Text | References | PDF (378.8 KB)

726 Views
21 CrossRef citations
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Review Article

Placental growth factor in cancer

Mieke Dewerchin PhD & Peter Carmeliet MD PhD

Pages: 1339-1354

Published online: 09 Oct 2014

AbstractforPlacental growth factor in cancer | Full Text | References | PDF (538.2 KB)

899 Views
51 CrossRef citations
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Research Article

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