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Placental growth factor in cancer

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Xiaotong Peng, Zhirong Zhang, Yanqun Mo, Junliang Liu, Shuo Wang & Huining Liu. (2021) Bioinformatics Analysis of Choriocarcinoma-Related MicroRNA-Transcription Factor-Target Gene Regulatory Networks and Validation of Key miRNAs. OncoTargets and Therapy 14, pages 3903-3919.
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Hamid Reza Nejabati, Zeinab Latifi, Tohid Ghasemnejad, Amir Fattahi & Mohammad Nouri. (2017) Placental growth factor (PlGF) as an angiogenic/inflammatory switcher: lesson from early pregnancy losses. Gynecological Endocrinology 33:9, pages 668-674.
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Articles from other publishers (49)

Nari Kim, Yousun Ko, Youngbin Shin, Jisuk Park, Amy Junghyun Lee, Kyung Won Kim & Junhee Pyo. (2023) Comprehensive Analysis for Anti-Cancer Target-Indication Prioritization of Placental Growth Factor Inhibitor (PGF) by Use of Omics and Patient Survival Data. Biology 12:7, pages 970.
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Wangyang Chen, Dongchao Xu, Qiang Liu, Yirong Wu, Yu Wang & Jianfeng Yang. (2023) Unraveling the heterogeneity of cholangiocarcinoma and identifying biomarkers and therapeutic strategies with single-cell sequencing technology. Biomedicine & Pharmacotherapy 162, pages 114697.
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Dhyana Sharma, Ian Zachary & Haiyan Jia. (2023) Mechanisms of Acquired Resistance to Anti-VEGF Therapy for Neovascular Eye Diseases. Investigative Opthalmology & Visual Science 64:5, pages 28.
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Anna K. Rekowska, Karolina Obuchowska, Magdalena Bartosik, Żaneta Kimber-Trojnar, Magdalena Słodzińska, Magdalena Wierzchowska-Opoka & Bożena Leszczyńska-Gorzelak. (2023) Biomolecules Involved in Both Metastasis and Placenta Accreta Spectrum—Does the Common Pathophysiological Pathway Exist?. Cancers 15:9, pages 2618.
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Arezoo ValipourHasan Namdar Ahmad AbadMehran VatanchianRoghaye Arezumand. (2023) Designing and Developing Enzyme-Linked Immunosorbent Assay Sandwich Kit for Measuring Placental Growth Factor Concentration. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 42:1, pages 3-8.
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Maria Grazia Atzori, Claudia Ceci, Federica Ruffini, Manuel Scimeca, Rosella Cicconi, Maurizio Mattei, Pedro Miguel Lacal & Grazia Graziani. (2022) The Anti-Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) D16F7 Monoclonal Antibody Inhibits Melanoma Adhesion to Soluble VEGFR-1 and Tissue Invasion in Response to Placenta Growth Factor. Cancers 14:22, pages 5578.
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Duk Ki Kim, Juhee Jeong, Dong Sun Lee, Do Young Hyeon, Geon Woo Park, Suwan Jeon, Kyung Bun Lee, Jin-Young Jang, Daehee Hwang, Ho Min Kim & Keehoon Jung. (2022) PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer. Nature Communications 13:1.
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Amelia J. McFarland, Pradipta R. Ray, Salman Bhai, Benjamin D. Levine & Theodore J. Price. (2022) RNA sequencing on muscle biopsy from a 5‐week bed rest study reveals the effect of exercise and potential interactions with dorsal root ganglion neurons. Physiological Reports 10:3.
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Limei Ao, Han Gao, Lifen Jia, Shimin Liu, Jie Guo, Bingzhen Liu & Qiumei Dong. (2022) Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway. Molecular Immunology 141, pages 13-20.
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Jean-Luc Raoul, Marie-Françoise Heymann, Frédéric Dumont, Alain Morel, Hélène Senellart & François Bertucci. (2021) Case Report: Grade 2 Metastatic Pancreatic Neuroendocrine Tumor With Progression of One Metastasis After Pregnancy to Grade 3 Large-Cell Neuroendocrine Carcinoma: One Case Cured by Resection With Genomic Characterization of the Two Components. Frontiers in Oncology 11.
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Jennifer Pasquier, Pegah Ghiabi, Lotfi Chouchane, Kais Razzouk, Shahin Rafii & Arash Rafii. (2020) Angiocrine endothelium: from physiology to cancer. Journal of Translational Medicine 18:1.
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Zumurelaiti Ainiwaer, Reyilanmu Maisaidi, Jing Liu, Lili Han, Sulaiya Husaiyin, Jing Lu & Mayinuer Niyazi. (2020) Genetic polymorphisms of PGF and TNFAIP2 genes related to cervical cancer risk among Uygur females from China. BMC Medical Genetics 21:1.
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Lays M. Sobral, Hannah M. Hicks, Janet K. Parrish, Tyler S. McCann, Joseph Hsieh, Andrew Goodspeed, James C. Costello, Joshua C. Black & Paul Jedlicka. (2020) KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma. Molecular Oncology 14:10, pages 2471-2486.
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John D. Aplin, Jenny E. Myers, Kate Timms & Melissa Westwood. (2020) Tracking placental development in health and disease. Nature Reviews Endocrinology 16:9, pages 479-494.
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Aimy Sebastian, Nicholas R. Hum, Kelly A. Martin, Sean F. Gilmore, Ivana Peran, Stephen W. Byers, Elizabeth K. Wheeler, Matthew A. Coleman & Gabriela G. Loots. (2020) Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer. Cancers 12:5, pages 1307.
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Jian Zhang, Jun Shi, Hao Ma, Lulu Liu, Li He, Chaoyi Qin, Dengshen Zhang, Yingqiang Guo & Renrong Gong. (2020) The placental growth factor attenuates intimal hyperplasia in vein grafts by improving endothelial dysfunction. European Journal of Pharmacology 868, pages 172856.
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Maria Grazia Atzori, Claudia Ceci, Federica Ruffini, Mauro Trapani, Maria Luisa Barbaccia, Lucio Tentori, Stefania D'Atri, Pedro Miguel Lacal & Grazia Graziani. (2019) Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib. Journal of Cellular and Molecular Medicine 24:1, pages 465-475.
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Zofia Ulańczyk, Anna Sobuś, Karolina Łuczkowska, Aleksandra Grabowicz, Katarzyna Mozolewska-Piotrowska, Krzysztof Safranow, Miłosz Kawa, Andrzej Pałucha, Mariusz Krawczyk, Piotr Sikora, Ewa Matczyńska, Bogusław Machaliński & Anna Machalińska. (2019) Associations of MicroRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism—An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration. International Journal of Molecular Sciences 20:22, pages 5750.
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Qiang Ma, Jing-Tao Gu, Bo Wang, Jun Feng, Lin Yang, Xiao-Wei Kang, Peng Duan, Xin Sun, Pei-Jun Liu & Ji-Chang Wang. (2019) PlGF signaling and macrophage repolarization contribute to the anti-neoplastic effect of metformin. European Journal of Pharmacology 863, pages 172696.
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E. R. Chernykh, O. Yu. Leplina, M. A. Tikhonova, E. V. Batorov & A. A. Ostanin. (2019) VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 SIGNALING AS A NOVEL MECHANISM OF T CELL SUPPRESSION IN TUMOR NEOANGIOGENESIS. Medical Immunology (Russia) 21:4, pages 653-660.
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Loredana Albonici, Maria Gabriella Giganti, Andrea Modesti, Vittorio Manzari & Roberto Bei. (2019) Multifaceted Role of the Placental Growth Factor (PlGF) in the Antitumor Immune Response and Cancer Progression. International Journal of Molecular Sciences 20:12, pages 2970.
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Khalid N.M. Abdelazeem, Barbora Droppova, Basma Sukkar, Tamer al-Maghout, Lisann Pelzl, Nefeli Zacharopoulou, Nagwa Hassan Ali Hassan, Kamal I. Abdel-Fattah, Christos Stournaras & Florian Lang. (2019) Upregulation of Orai1 and STIM1 expression as well as store-operated Ca2+ entry in ovary carcinoma cells by placental growth factor. Biochemical and Biophysical Research Communications 512:3, pages 467-472.
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Andrea Caporale, Aaron D. Martin, Dominga Capasso, Giuseppina Focà, Annamaria Sandomenico, Luca Domenico D'Andrea, Paolo Grieco, Menotti Ruvo & Nuzianna Doti. (2019) Short PlGF ‐derived peptides bind VEGFR ‐1 and VEGFR ‐2 in vitro and on the surface of endothelial cells . Journal of Peptide Science 25:5, pages e3146.
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Kyuhyun Lee, Sung-Tae Yun, Byung-Yoon Ahn & Eui-Cheol Jo. (2019) Apolipoprotein(a) Kringles for Gene Therapy of Colon Cancer. Biotechnology and Bioprocess Engineering 24:1, pages 163-175.
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Dimitar Tasev, Laura Dekker-Vroling, Michiel van Wijhe, Henk J. Broxterman, Pieter Koolwijk & Victor W. M. van Hinsbergh. (2018) Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential. Frontiers in Medicine 5.
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Pedro Miguel Lacal & Grazia Graziani. (2018) Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors. Pharmacological Research 136, pages 97-107.
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Gianfranco Natale & Guido Bocci. (2018) Does metronomic chemotherapy induce tumor angiogenic dormancy? A review of available preclinical and clinical data. Cancer Letters 432, pages 28-37.
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Yueh-Ho Chiu, Ming-Ren Yang, Liang-Jie Wang, Ming-Hon Chen, Geen-Dong Chang & Hungwen Chen. (2018) New insights into the regulation of placental growth factor gene expression by the transcription factors GCM1 and DLX3 in human placenta. Journal of Biological Chemistry 293:25, pages 9801-9811.
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Huaifeng Li, Yunpeng Jin, Yunping Hu, Lin Jiang, Fatao Liu, Yijian Zhang, Yajuan Hao, Shili Chen, Xiangsong Wu & Yingbin Liu. (2018) The PLGF /c‐ MYC /miR‐19a axis promotes metastasis and stemness in gallbladder cancer . Cancer Science 109:5, pages 1532-1544.
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Marta Skoda, Aleksandra Stangret & Dariusz Szukiewicz. (2018) Fractalkine and placental growth factor: A duet of inflammation and angiogenesis in cardiovascular disorders. Cytokine & Growth Factor Reviews 39, pages 116-123.
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Qin Meng, Pengjing Duan, Lin Li & Yongmei Miao. (2018) Expression of Placenta Growth Factor Is Associated with Unfavorable Prognosis of Advanced-Stage Serous Ovarian Cancer. The Tohoku Journal of Experimental Medicine 244:4, pages 291-296.
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Maria Grazia Atzori, Lucio Tentori, Federica Ruffini, Claudia Ceci, Elena Bonanno, Manuel Scimeca, Pedro Miguel Lacal & Grazia Graziani. (2018) The Anti–Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo. Journal of Pharmacology and Experimental Therapeutics 364:1, pages 77-86.
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Xichun Sun & Xiwu Liu. (2017) Cancer metastasis: enactment of the script for human reproductive drama. Cancer Cell International 17:1.
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K. Santalahti, A. Havulinna, M. Maksimow, T. Zeller, S. Blankenberg, A. Vehtari, H. Joensuu, S. Jalkanen, V. Salomaa & M. Salmi. (2017) Plasma levels of hepatocyte growth factor and placental growth factor predict mortality in a general population: a prospective cohort study. Journal of Internal Medicine 282:4, pages 340-352.
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Wei-Bin Wu, Yue-Ying Xu, Wei-Wei Cheng, Bo Yuan, Jiu-Ru Zhao, Yan-Lin Wang & Hui-Juan Zhang. (2017) Decreased PGF may contribute to trophoblast dysfunction in fetal growth restriction. Reproduction 154:3, pages 319-329.
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E Al Kahtani, Z Xu, S Al Rashaed, L Wu, A Mahale, J Tian, E B Abboud, N G Ghazi, I Kozak, V Gupta, J F Arevalo & E J Duh. (2016) Vitreous levels of placental growth factor correlate with activity of proliferative diabetic retinopathy and are not influenced by bevacizumab treatment. Eye 31:4, pages 529-536.
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Andreas BikfalviAndreas Bikfalvi. 2017. A Brief History of Blood and Lymphatic Vessels. A Brief History of Blood and Lymphatic Vessels 99 105 .
Andreas BikfalviAndreas Bikfalvi. 2017. A Brief History of Blood and Lymphatic Vessels. A Brief History of Blood and Lymphatic Vessels 67 89 .
Gianfranco Natale & Guido Bocci. 2017. Tumor Dormancy and Recurrence. Tumor Dormancy and Recurrence 31 49 .
Vishwajith Sridharan, Danielle N. Margalit, Stephanie A. Lynch, Mariano Severgnini, F. Stephen Hodi, Robert I. Haddad, Roy B. Tishler & Jonathan D. Schoenfeld. (2016) Effects of definitive chemoradiation on circulating immunologic angiogenic cytokines in head and neck cancer patients. Journal for ImmunoTherapy of Cancer 4:1.
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Theresa Vilsmaier, Brigitte Rack, Wolfgang Janni, Udo Jeschke & Tobias Weissenbacher. (2016) Angiogenic cytokines and their influence on circulating tumour cells in sera of patients with the primary diagnosis of breast cancer before treatment. BMC Cancer 16:1.
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Grazia Graziani, Federica Ruffini, Lucio Tentori, Manuel Scimeca, Annalisa S. Dorio, Maria Grazia Atzori, Cristina M. Failla, Veronica Morea, Elena Bonanno, Stefania D’Atri & Pedro M. Lacal. (2016) Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding. Oncotarget 7:45, pages 72868-72885.
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Lindsey Devisscher, Margherita Vieri, Susan E. Logue, Jens Panse, Anja Geerts, Hans van Vlierberghe, Eric Chevet, Adrienne M. Gorman, Afshin Samali & Behzad Kharabi Masouleh. (2016) Targeting the angio-proteostasis network: Combining the forces against cancer. Pharmacology & Therapeutics 167, pages 1-12.
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Roghaye Arezumand, Reza Mahdian, Sirous Zeinali, Gholamreza Hassanzadeh-Ghassabeh, Kamran Mansouri, Hossein Khanahmad, Nabiollah Namvar-asl, Hamzeh Rahimi, Mahdi Behdani, Reza Ahangari Cohan, Mehdi Eavazalipour, Ali Ramazani & Serge Muyldermans. (2016) Identification and characterization of a novel nanobody against human placental growth factor to modulate angiogenesis. Molecular Immunology 78, pages 183-192.
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Christian Lange, Erik Storkebaum, Carmen Ruiz de Almodóvar, Mieke Dewerchin & Peter Carmeliet. (2016) Vascular endothelial growth factor: a neurovascular target in neurological diseases. Nature Reviews Neurology 12:8, pages 439-454.
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ELENA PAGANI, FEDERICA RUFFINI, GIAN CARLO ANTONINI CAPPELLINI, ALESSANDRO SCOPPOLA, CRISTINA FORTES, PAOLO MARCHETTI, GRAZIA GRAZIANI, STEFANIA D'ATRI & PEDRO MIGUEL LACAL. (2016) Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness. International Journal of Oncology 48:4, pages 1581-1589.
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Rayana Leal Luna, Vanessa R. Kay, Matthew T. Rätsep, Kasra Khalaj, Mallikarjun Bidarimath, Nichole Peterson, Peter Carmeliet, Albert Jin & B. Anne Croy. (2016) Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Molecular Human Reproduction 22:2, pages 130-142.
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Anna Kuchnio, Mieke Dewerchin & Peter Carmeliet. (2015) The PHD2 oxygen sensor paves the way to metastasis. Oncotarget 6:34, pages 35149-35150.
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Arnela Redzovic, Tamara Gulic, Gordana Laskarin, Senija Eminovic, Herman Haller & Daniel Rukavina. (2015) Heat-Shock Proteins 70 Induce Pro-Inflammatory Maturation Program in Decidual CD1a + Dendritic Cells . American Journal of Reproductive Immunology 74:1, pages 38-53.
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