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Expert Opinion on Therapeutic Targets Volume 19, 2015 - Issue 6
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Original Research

Neutralizations of IL-17A and IL-21 regulate regulatory T cell/T-helper 17 imbalance via T-helper 17-associated signaling pathway in immune thrombocytopenia

Yu HuShandong University, Qilu Hospital, Department of Hematology, Jinan, [email protected];Shandong University, Qilu Hospital, Department of Chemotherapy, Jinan, China
,
Xiuwen WangShandong University, Qilu Hospital, Department of Chemotherapy, Jinan, China
,
Shuang YuShandong University, Qilu Hospital, Department of Hematology, Jinan, [email protected]
,
Yu HouShandong University, Qilu Hospital, Department of Hematology, Jinan, [email protected]
,
Daoxin MaShandong University, Qilu Hospital, Department of Hematology, Jinan, [email protected]
&
Ming HouShandong University, Qilu Hospital, Department of Hematology, Jinan, [email protected];Shandong University, Qilu Hospital, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Jinan, China
Pages 723-732 | Published online: 14 May 2015

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Jian-Qin Li, Jian-Mei Tian, Xiao-Ru Fan, Zhao-Yue Wang, Jing Ling, Xiao-Fang Wu, Fei-Yun Yang & Ya-Lin Xia. (2020) miR-106b-5p induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura through NR4A3/Foxp3 pathway. Cell Cycle 19:11, pages 1265-1274.
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Hans-Klaus Goischke. (2019) Vitamin D supplementation for the prevention or depletion of side effects of therapy with alemtuzumab in multiple sclerosis. Therapeutics and Clinical Risk Management 15, pages 891-904.
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Yan Tan, Wei Chen, Chun Liu, Xiaoya Zheng, Ai Guo & Jian Long. (2019) Effect of IL-21 on the Balance of Th17 Cells/Treg Cells in the Pathogenesis of Graves’ Disease. Endocrine Research 44:4, pages 138-147.
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Articles from other publishers (9)

Panpan HanYu Hou, Yajing ZhaoYang LiuTianshu YuYunqi Sun, Haoyi WangPengcheng XuGuosheng LiTao Sun, Xiang Hu, Xinguang Liu, Lizhen Li, Jun Peng, Hai Zhou & Ming Hou. (2021) Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia. Blood 138:8, pages 674-688.
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Lei FAN, Menghan SHA, Wei LI, Qingling KANG, Jianli WU, Suhua CHEN & Nan YU. (2021) Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance. Journal of Reproduction and Development 67:6, pages 359-368.
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Sylwia Sulimiera Michalak, Anna Olewicz-Gawlik, Joanna Rupa-Matysek, Edyta Wolny-Rokicka, Elżbieta Nowakowska & Lidia Gil. (2020) Autoimmune hemolytic anemia: current knowledge and perspectives. Immunity & Ageing 17:1.
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Bruno Fattizzo & Wilma Barcellini. (2020) Autoimmune Cytopenias in Chronic Lymphocytic Leukemia: Focus on Molecular Aspects. Frontiers in Oncology 9.
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Yuan-Yuan Chen, Yan-Qiong Zhou, Ning Zhao, Yao Zhang, Wei-qun Xu & Yong-Min Tang. (2019) Evaluation of IVIG response in relation to Th1/Th2 cytokines in pediatricm immune thrombocytopenia. Cytokine 120, pages 234-241.
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Wen-bin Liu, Sai Li, Xiao-ling Yu, Tie-ying Dai & Rui-lan Gao. (2019) Research Progress on Chinese Medicine Immunomodulatory Intervention for Chronic Primary Immune Thrombocytopenia: Targeting Cellular Immunity. Chinese Journal of Integrative Medicine 25:7, pages 483-489.
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Takaaki Maekawa, Yukiko Osawa, Yosuke Okada, Noriaki Tachi, Masahiro Teramoto, Toshikuni Kawamura, Toshikatsu Horiuchi, Shoichiro Kato, Ayako Kobayashi, Shinichi Kobayashi, Ken Sato & Fumihiko Kimura. (2018) Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone. PLOS ONE 13:11, pages e0207149.
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YiChan Zhang, TingTing Ma, Xuan Zhou, JunHao Chen & Juan Li. (2018) Circulating level of Th17 cells is associated with sensitivity to glucocorticoids in patients with immune thrombocytopenia. International Journal of Hematology 107:4, pages 442-450.
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Yu Wei & Ming Hou. (2016) T cells in the pathogenesis of immune thrombocytopenia. Seminars in Hematology 53, pages S13-S15.
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