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Review

STAT proteins as novel targets for cancer drug discovery

Pages 409-422 | Published online: 25 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Adam Zalewski & Jacek C. Szepietowski. (2023) Topical and systemic JAK inhibitors in hand eczema – a narrative review. Expert Review of Clinical Immunology 19:4, pages 365-373.
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Yufei Fu, Fanfan Zhu, Zhongjun Ma, Bin Lv, Xi Wang, Chunyan Dai, Xiaoqiong Ma, Pei Liu, Hang Lv, Xin Chen, Zhe Chen & Li Shen. (2021) Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 Signaling. OncoTargets and Therapy 14, pages 301-314.
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Mahnaz Mohammadi Kian, Mahdieh Salemi, Mohammad Bahadoran, Atousa Haghi, Nasrin Dashti, Saeed Mohammadi, Shahrbano Rostami, Bahram Chahardouli, Davood Babakhani & Mohsen Nikbakht. (2020) Curcumin Combined with Thalidomide Reduces Expression of STAT3 and Bcl-xL, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines. Drug Design, Development and Therapy 14, pages 185-194.
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Giulio Poli, Arianna Gelain, Federica Porta, Akira Asai, Adriano Martinelli & Tiziano Tuccinardi. (2016) Identification of a new STAT3 dimerization inhibitor through a pharmacophore-based virtual screening approach. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1011-1017.
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Yan Liang, Hai-Feng Pan & Dong-Qing Ye. (2014) Therapeutic potential of STAT4 in autoimmunity. Expert Opinion on Therapeutic Targets 18:8, pages 945-960.
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Antonio Lavecchia, Carmen Di Giovanni & Carmen Cerchia. (2014) Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature. Expert Opinion on Therapeutic Patents 24:4, pages 383-400.
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Karolina Swiatek-Machado, Jakub Mieczkowski, Aleksandra Ellert-Miklaszewska, Piotr Swierk, Izabela Fokt, Slawomir Szymanski, Stanislaw Skora, Wiesław Szeja, Grzegorz Grynkiewicz, Bogdan Lesyng, Waldemar Priebe & Bozena Kaminska. (2012) Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells. Cancer Biology & Therapy 13:8, pages 657-670.
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Raj Kishore & Suresh K. Verma. (2012) Roles of STATs signaling in cardiovascular diseases. JAK-STAT 1:2, pages 118-124.
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Lei Li, Jin Zeng, Ye Gao & Dalin He. (2010) Targeting silibinin in the antiproliferative pathway. Expert Opinion on Investigational Drugs 19:2, pages 243-255.
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Mingzhu Zhu, Lei Gao, Xia Li, Zhicheng Liu, Chun Xu, Yuqing Yan, Erin Walker, Wei Jiang, Bin Su, Xiujie Chen & Hui Lin. (2009) The analysis of the drug–targets based on the topological properties in the human protein–protein interaction network. Journal of Drug Targeting 17:7, pages 524-532.
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Peibin Yue & James Turkson. (2009) Targeting STAT3 in cancer: how successful are we?. Expert Opinion on Investigational Drugs 18:1, pages 45-56.
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Madeleine Duvic & Jenny Vu. (2007) Update on the treatment of cutaneous T-cell lymphoma (CTCL): Focus on vorinostat. Biologics: Targets and Therapy 1:4, pages 377-392.
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Thomas Meyer & Uwe Vinkemeier. (2007) STAT nuclear translocation: potential for pharmacological intervention. Expert Opinion on Therapeutic Targets 11:10, pages 1355-1365.
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Madeleine Duvic & Jenny Vu. (2007) Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma. Expert Opinion on Investigational Drugs 16:7, pages 1111-1120.
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Corina Borghouts, Christian Kunz & Bernd Groner. (2005) Peptide aptamers: recent developments for cancer therapy. Expert Opinion on Biological Therapy 5:6, pages 783-797.
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Marta Rusek, Joanna Smith, Kamel El-Khatib, Kennedy Aikins, Stanisław J. Czuczwar & Ryszard Pluta. (2023) The Role of the JAK/STAT Signaling Pathway in the Pathogenesis of Alzheimer’s Disease: New Potential Treatment Target. International Journal of Molecular Sciences 24:1, pages 864.
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Chandrabose Selvaraj, Karthik Raja Ramalingam, Devadasan Velmurugan & Sanjeev Kumar Singh. 2023. Regulation of Downstream Targets. Regulation of Downstream Targets 1 20 .
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Kagiso Laka, Ladislaus Mdee & Zukile Mbita. (2022) Drimia calcarata Bulb Extracts Deactivate the PI3K Signalling Pathway in Cervical HPV-18 Positive HeLa Cells. Clinical Complementary Medicine and Pharmacology 2:4, pages 100054.
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Elnaz Faghfuri, Mohsen Sagha & Amir Hossein Faghfouri. (2021) The Cytotoxicity Effect of Curcumin Loaded Folic Acid Conjugated-Nanoparticles on Breast Cancer Cells and Its Association with Inhibition of STAT3 Phosphorylation. Journal of Cluster Science 33:5, pages 2037-2044.
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Shishay Girmay, Hafiz Ishfaq Ahmad & Quratul Ain Zahra. (2022) A Simulation Analysis and Screening of Deleterious Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Sheep LEP Gene. BioMed Research International 2022, pages 1-9.
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Mariia Radaeva, Anh-Tien Ton, Michael Hsing, Fuqiang Ban & Artem Cherkasov. (2021) Drugging the ‘undruggable’. Therapeutic targeting of protein–DNA interactions with the use of computer-aided drug discovery methods. Drug Discovery Today 26:11, pages 2660-2679.
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Fan Luo, Fei-Teng Lu, Miao-Zhen Qiu, Ting Zhou, Wen-Juan Ma, Min Luo, Kang-Mei Zeng, Qiu-Yun Luo, Wen-Tao Pan, Lin Zhang, Zeng-Fei Xia, Zhong-Han Zhang, Jia-Xin Cao, Hong-Yun Zhao, Li Zhang & Da-Jun Yang. (2021) Gemcitabine and APG-1252, a novel small molecule inhibitor of BCL-2/BCL-XL, display a synergistic antitumor effect in nasopharyngeal carcinoma through the JAK-2/STAT3/MCL-1 signaling pathway. Cell Death & Disease 12:8.
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Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi & Carmela Saturnino. (2021) Carbazole Derivatives as STAT Inhibitors: An Overview. Applied Sciences 11:13, pages 6192.
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Mohammad rafi Khezri, Hassan Malekinejad, Naime Majidi-Zolbanin & Morteza Ghasemnejad-Berenji. (2021) Anticancer potential of metformin: focusing on gastrointestinal cancers. Cancer Chemotherapy and Pharmacology 87:5, pages 587-598.
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Dingding Gao, Nan Jin, Yixian Fu, Yueyue Zhu, Yujie Wang, Ting Wang, Yuehong Chen, Mingming Zhang, Qiang Xiao, Min Huang & Yingxia Li. (2021) Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors. European Journal of Medicinal Chemistry 216, pages 113333.
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Mehmet Berköz, Ferbal Özkan-Yılmaz, Arzu Özlüer-Hunt, Mirosław Krośniak, Ömer Türkmen, Duygu Korkmaz & Sıddık Keskin. (2021) Artesunate inhibits melanoma progression in vitro via suppressing STAT3 signaling pathway. Pharmacological Reports 73:2, pages 650-663.
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Jamie V. Shiah, Jennifer R. Grandis & Daniel E. Johnson. (2021) Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides. Molecular Cancer Therapeutics 20:2, pages 219-228.
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Meaghan H. Hancock, Jennifer Mitchell, Felicia D. Goodrum & Jay A. Nelson. (2020) Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways . mSphere 5:4.
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Xin Qi, Meng Li, Xiao-min Zhang, Xiu-fen Dai, Jian Cui, De-hai Li, Qian-qun Gu, Zhi-hua Lv & Jing Li. (2020) Trichothecin Inhibits Cancer-Related Features in Colorectal Cancer Development by Targeting STAT3. Molecules 25:10, pages 2306.
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Samarwadee Plianwong, Bindu Thapa, Remant Bahadur KC, Cezary Kucharski, Theerasak Rojanarata & Hasan Uludağ. (2020) Enabling Combinatorial siRNA Delivery against Apoptosis-Related Proteins with Linoleic Acid and α-Linoleic Acid Substituted Low Molecular Weight Polyethylenimines. Pharmaceutical Research 37:3.
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Sundas Arshad, Muhammad Naveed, Mahad Ullia, Khadija Javed, Ayesha Butt, Masooma Khawar & Fazeeha Amjad. (2020) Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges. Genetics and Molecular Biology 43:1.
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Karolina Swiatek-Machado & Bozena Kaminska. 2020. Glioma Signaling. Glioma Signaling 203 222 .
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Bruna Gazzi de Lima-Seolin, Ashley Nemec-Bakk, Heidi Forsyth, Stefanie Kirk, Alex Sander da Rosa Araujo, Paulo Cavalheiro Schenkel, Adriane Belló-Klein & Neelam Khaper. (2019) Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine. Oxidative Medicine and Cellular Longevity 2019, pages 1-11.
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Stella Sravanthi V.Bhagath Kumar Palaka, Gnana vel, Rengarajan Venkatesan, Dinakara Rao Ampasala & Latha Periyasamy. (2019) Identification of novel inhibitors of signal transducer and activator of transcription 3 over signal transducer and activator of transcription 1 for the treatment of breast cancer by in-silico and in-vitro approach. Process Biochemistry 82, pages 153-166.
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Tatsuya Koseki, Naoya Suehiro, Yoshiaki Masuda, Nao Miyoshi, Daisuke Muraoka, Naohisa Ogo & Akira Asai. (2019) Discovery of a New STAT3 Inhibitor Acting on the Linker Domain. Biological and Pharmaceutical Bulletin 42:5, pages 792-800.
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Eun Ji Lee, Su-Jung Kim, Young-Il Hahn, Hyo-Jin Yoon, Bitnara Han, Kyeojin Kim, Seungbeom Lee, Kwang Pyo Kim, Young Ger Suh, Hye-Kyung Na & Young-Joon Surh. (2019) 15-Keto prostaglandin E2 suppresses STAT3 signaling and inhibits breast cancer cell growth and progression. Redox Biology 23, pages 101175.
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Agnieszka Krzyzanowska, Nicholas Don‐Doncow, Felicia Elena Marginean, Alexander Gaber, R. William Watson, Rebecka Hellsten & Anders Bjartell. (2019) Expression of tSTAT3, pSTAT3 727 , and pSTAT3 705 in the epithelial cells of hormone‐naïve prostate cancer . The Prostate 79:7, pages 784-797.
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Shengling Fu, Xiang Chen, Hui-Wen Lo & Jiayuh Lin. (2019) Combined bazedoxifene and paclitaxel treatments inhibit cell viability, cell migration, colony formation, and tumor growth and induce apoptosis in breast cancer. Cancer Letters 448, pages 11-19.
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Eleanor C. FiedlerMichael T. Hemann. (2019) Aiding and Abetting: How the Tumor Microenvironment Protects Cancer from Chemotherapy. Annual Review of Cancer Biology 3:1, pages 409-428.
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Jia‐Peng Li, Yuan Xiang, Li‐Juan Fan, Ao Yao, Hui Li & Xing‐Hua Liao. (2018) Long noncoding RNA H19 competitively binds miR‐93‐5p to regulate STAT3 expression in breast cancer. Journal of Cellular Biochemistry 120:3, pages 3137-3148.
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Chin-Yap Loh, Aditya Arya, Ahmed Fadhil Naema, Won Fen Wong, Gautam Sethi & Chung Yeng Looi. (2019) Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication. Frontiers in Oncology 9.
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Yang Yang & Zhi Shi. 2019. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy 53 65 .
Shuntao Wang, Lili Yu, Wei Shi, Xueqin Li & Lixiu Yu. (2018) Prognostic roles of signal transducers and activators of transcription family in human breast cancer. Bioscience Reports 38:6.
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Dan Li, Gangcheng Wang, Guoguo Jin, Ke Yao, Zhenjiang Zhao, Liangyu Bie, Yongjun Guo, Ning Li, Wenying Deng, Xiaobin Chen, Beibei Chen, Yuanyuan Liu, Suxia Luo & Zhiping Guo. (2018) Resveratrol suppresses colon cancer growth by targeting the AKT/STAT3 signaling pathway. International Journal of Molecular Medicine.
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Ajaz A. Bhat, Heng Lu, Mohammed Soutto, Anthony Capobianco, Priyamvada Rai, Alexander Zaika & Wael El-Rifai. (2018) Exposure of Barrett’s and esophageal adenocarcinoma cells to bile acids activates EGFR–STAT3 signaling axis via induction of APE1. Oncogene 37:46, pages 6011-6024.
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Pingyu Zhang & Huaiyi Huang. (2018) Future potential of osmium complexes as anticancer drug candidates, photosensitizers and organelle-targeted probes. Dalton Transactions 47:42, pages 14841-14854.
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In‐Hyoung Yang, Won Jung, Lee‐Han Kim, Ji‐Ae Shin, Nam‐Pyo Cho, Seong Doo Hong, Kyoung‐Ok Hong & Sung‐Dae Cho. (2018) Nitidine chloride represses Mcl‐1 protein via lysosomal degradation in oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 47:9, pages 823-829.
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Ilenia Segatto, Gustavo Baldassarre & Barbara Belletti. (2018) STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context. International Journal of Molecular Sciences 19:9, pages 2818.
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Paul J. M. Jackson, Shirin Jamshidi & Doaa B. Farag. 2018. Small-molecule Transcription Factor Inhibitors in Oncology. Small-molecule Transcription Factor Inhibitors in Oncology 42 54 .
Kaja Rupar, Sausan A. Moharram, Julhash U. Kazi & Lars Rönnstrand. (2018) SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation. Scientific Reports 8:1.
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Francisco Lopez-Tapia, Christine Brotherton-Pleiss, Peibin Yue, Heide Murakami, Ana Carolina Costa Araujo, Bruna Reis dos Santos, Erin Ichinotsubo, Anna Rabkin, Raj Shah, Megan Lantz, Suzie Chen, Marcus A. Tius & James Turkson. (2018) Linker Variation and Structure–Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors. ACS Medicinal Chemistry Letters 9:3, pages 250-255.
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Md. Abdullah Al Noman, Tasnova Hossain, Monira Ahsan, Shirin JamshidiChoudhury Mahmood Hasan & Khondaker Miraz Rahman. (2018) Crispenes F and G, cis -Clerodane Furanoditerpenoids from Tinospora crispa , Inhibit STAT3 Dimerization . Journal of Natural Products 81:2, pages 236-242.
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Jingtong Pan, Wenyi Ruan, Mengyao Qin, Yueming Long, Tao Wan, Kaiyue Yu, Yuanhao Zhai, Chuanbin Wu & Yuehong Xu. (2018) Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles. Scientific Reports 8:1.
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Kaja Rupar, Julhash U. Kazi & Lars Rönnstrand. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 2772 2776 .
Sankar Jagadeeshan, Diana David, S. Jisha, S. Manjula & S. Asha Nair. (2017) Solanum nigrum Unripe fruit fraction attenuates Adriamycin resistance by down-regulating multi-drug resistance protein (Mdr)-1 through Jak-STAT pathway. BMC Complementary and Alternative Medicine 17:1.
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Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy & Faisal Thayyullathil. (2017) Molecular targets and anticancer potential of sanguinarine—a benzophenanthridine alkaloid. Phytomedicine 34, pages 143-153.
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Shegan Gao, Shuoguo Li, Xiaoxian Duan, Zhen Gu, Zhikun Ma, Xiang Yuan, Xiaoshan Feng & Huizhi Wang. (2017) Inhibition of glycogen synthase kinase 3 beta (GSK3β) suppresses the progression of esophageal squamous cell carcinoma by modifying STAT3 activity. Molecular Carcinogenesis 56:10, pages 2301-2316.
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Shuai Li, Xiaochen Guo, Teng Zhang, Nan Wang, Junyan Li, Pengfei Xu, Shengqi Zhang, Guiping Ren & Deshan Li. (2017) Fibroblast growth factor 21 ameliorates high glucose-induced fibrogenesis in mesangial cells through inhibiting STAT5 signaling pathway. Biomedicine & Pharmacotherapy 93, pages 695-704.
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Shan-Shan Liu, Ning Liu, Meng-Yao Liu, Lei Sun, Wu-Yan Xia, Hong-Min Lu, Yu-Jie Fu, Guo-Liang Yang, Juan-Jie Bo, Xiao-Xing Liu, Haizhong Feng, Hailong Wu, Lin-Feng Li & Jian-Xin Gao. (2017) An unusual intragenic promoter of PIWIL2 contributes to aberrant activation of oncogenic PL2L60 . Oncotarget 8:28, pages 46104-46120.
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Nicole M. Jackson & Brian P. Ceresa. (2017) EGFR-mediated apoptosis via STAT3. Experimental Cell Research 356:1, pages 93-103.
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Koji OsukaYasuo WatanabeNobuteru UsudaMasahiro AoyamaKenichiro IwamiMikinobu TakeuchiTakeya WatabeMasakazu Takayasu. (2017) Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas. Journal of Neurotrauma 34:11, pages 1996-2000.
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Tyvette S. Hilliard, Gabriella Miklossy, Christopher Chock, Peibin Yue, Philip Williams & James Turkson. (2017) 15α-methoxypuupehenol Induces Antitumor Effects In Vitro and In Vivo against Human Glioblastoma and Breast Cancer Models . Molecular Cancer Therapeutics 16:4, pages 601-613.
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Quyen Thu Bui, Ji Hye Im, Sung Baek Jeong, Young-Mi Kim, Sung Chul Lim, Bumseok Kim & Keon Wook Kang. (2017) Essential role of Notch4/STAT3 signaling in epithelial–mesenchymal transition of tamoxifen-resistant human breast cancer. Cancer Letters 390, pages 115-125.
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Bo Li & Chen Huang. (2017) Regulation of EMT by STAT3 in gastrointestinal cancer (Review). International Journal of Oncology 50:3, pages 753-767.
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Roberta Cirincione, Federica Maria Di Maggio, Giusi Irma Forte, Luigi Minafra, Valentina Bravatà, Laura Castiglia, Vincenzo Cavalieri, Giovanni Borasi, Giorgio Russo, Domenico Lio, Cristina Messa, Maria Carla Gilardi & Francesco Paolo Cammarata. (2017) High-Intensity Focused Ultrasound– and Radiation Therapy–Induced Immuno-Modulation: Comparison and Potential Opportunities. Ultrasound in Medicine & Biology 43:2, pages 398-411.
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Ildefonso Alves da Silva Junior, Simone Cardozo Stone, Renata Marques Rossetti, Sonia Jancar & Ana Paula Lepique. (2017) Modulation of Tumor-Associated Macrophages (TAM) Phenotype by Platelet-Activating Factor (PAF) Receptor. Journal of Immunology Research 2017, pages 1-10.
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James Turkson. 2017. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer 695 707 .
Akira Asai & Kazuyuki Takakuma. 2017. SH2 Domains. SH2 Domains 163 172 .
Chenbo Ding, Longmei Li, Taoyu Yang, Xiaobo Fan & Guoqiu Wu. (2016) Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model. BMC Cancer 16:1.
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Meihua Liang, Fei Zhan, Juan Zhao, Qi Li, Jiazi Wuyang, Guannan Mu, Dianjun Li, Yanqiao Zhang & Xiaoyi Huang. (2016) CPA-7 influences immune profile and elicits anti-prostate cancer effects by inhibiting activated STAT3. BMC Cancer 16:1.
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Li-Juan Liu, Wanhe Wang, Tian-Shu Kang, Jia-Xin Liang, Chenfu Liu, Daniel W. J. Kwong, Vincent Kam Wai Wong, Dik-Lung Ma & Chung-Hang Leung. (2016) Antagonizing STAT5B dimerization with an osmium complex. Scientific Reports 6:1.
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Bin Xiao, Dongjing Lin, Xuan Zhang, Meilan Zhang & Xuewu Zhang. (2016) TTF1, in the Form of Nanoparticles, Inhibits Angiogenesis, Cell Migration and Cell Invasion In Vitro and In Vivo in Human Hepatoma through STAT3 Regulation. Molecules 21:11, pages 1507.
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Shu Liu, Chunmei Hu, Yingxue Wang, Guang Shi, Yarong Li & Huang Wu. (2016) miR-124 inhibits proliferation and invasion of human retinoblastoma cells by targeting STAT3. Oncology Reports 36:4, pages 2398-2404.
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Yan-hong Liu, Jia-lu Jin, Yu-zhe Wang, Ying Tan, Ying-ying Zhou, Ting Peng, Feng Li, Wan-dong Liang, Pascal Chartrand, Yu-yang Jiang & Zhi-fa Shen. (2016) Protrusion-localized STAT3 mRNA promotes metastasis of highly metastatic hepatocellular carcinoma cells in vitro. Acta Pharmacologica Sinica 37:6, pages 805-813.
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Dingding Gao, Qiang Xiao, Mingming Zhang & Yingxia Li. (2016) Design, synthesis and biological evaluation of benzyloxyphenyl-methylaminophenol derivatives as STAT3 signaling pathway inhibitors. Bioorganic & Medicinal Chemistry 24:11, pages 2549-2558.
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Roxane Khoogar, Byung-Chang Kim, Jay Morris & Michael J. Wargovich. (2016) Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer. American Journal of Physiology-Gastrointestinal and Liver Physiology 310:9, pages G629-G644.
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TAO PENG, LIXIANG ZHOU, LING ZUO & YONGXIN LUAN. (2016) miR-506 functions as a tumor suppressor in glioma by targeting STAT3. Oncology Reports 35:2, pages 1057-1064.
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Peibin Yue, Francisco Lopez-Tapia, David Paladino, Yifei Li, Chih-Hong Chen, Andrew T. Namanja, Tyvette Hilliard, Yuan Chen, Marcus A. Tius & James Turkson. (2016) Hydroxamic Acid and Benzoic Acid–Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In Vitro and In Vivo . Cancer Research 76:3, pages 652-663.
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Elango Bhakkiyalakshmi, Natarajan Suganya, Dornadula Sireesh, Kannan Krishnamurthi, Sivanesan Saravana Devi, Palanisamy Rajaguru & Kunka Mohanram Ramkumar. (2016) Carvacrol induces mitochondria-mediated apoptosis in HL-60 promyelocytic and Jurkat T lymphoma cells. European Journal of Pharmacology 772, pages 92-98.
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Shih‐Chiang Huang, Chien‐Feng Li, Yu‐Chien Kao, I‐Chieh Chuang, Hui‐Chun Tai, Jen‐Wei Tsai, Shih‐Chen Yu, Hsuan‐Ying Huang, Jui Lan, Shao‐Lun Yen, Po‐Chun Lin & Tse‐Ching Chen. (2015) The clinicopathological significance of NAB 2‐ STAT 6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors . Cancer Medicine 5:2, pages 159-168.
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