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Risk versus risk: a review of benzodiazepine reduction in older adults

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Mojtaba Vaismoradi, Shazia Jamshed, Stefan Lorenzl & Piret Paal. (2021) PRN Medicines Management for Older People with Long-Term Mental Health Disorders in Home Care. Risk Management and Healthcare Policy 14, pages 2841-2849.
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Lynsey Seim, Priyanka Vijapura, Sandeep Pagali & M Caroline Burton. (2020) Common substance use disorders in older adults. Hospital Practice 48:sup1, pages 48-55.
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Tauheed Zaman, Tessa L. Rife, Steven L. Batki & David L. Pennington. (2018) An electronic intervention to improve safety for pain patients co-prescribed chronic opioids and benzodiazepines. Substance Abuse 39:4, pages 441-448.
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Emily Reeve, Frank Moriarty, Rayan Nahas, Justin P. Turner, Lisa Kouladjian O’Donnell & Sarah N. Hilmer. (2018) A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms. Expert Opinion on Drug Safety 17:1, pages 39-49.
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Articles from other publishers (54)

Karn Chahal, Matthew Glass, Jamie Falk, Alexander Singer & Christine Leong. (2023) Patient values and preferences regarding communicating risk versus benefit of benzodiazepine initiation: A cross‐sectional survey study. Health Science Reports 6:12.
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Nathaniel F. Watson, Ruth M. Benca, Andrew D. Krystal, William V. McCall & David N. Neubauer. (2023) Alliance for Sleep Clinical Practice Guideline on Switching or Deprescribing Hypnotic Medications for Insomnia. Journal of Clinical Medicine 12:7, pages 2493.
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Joshua Niznik, Stefanie P. Ferreri, Lori Armistead, Benjamin Urick, Mary-Haston Vest, Liang Zhao, Tamera Hughes, J. Marvin McBride & Jan Busby-Whitehead. (2022) A deprescribing medication program to evaluate falls in older adults: methods for a randomized pragmatic clinical trial. Trials 23:1.
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Savannah Gerardi, David Sperlea, Shirel Ora-Lee Levy, Kaitlin Bondurant-David, Sébastien Dang, Pierre-Marie David, Annie Lizotte, Lysane Senécal, François Paquette & Marie-Claude Vanier. (2022) Implementation of targeted deprescribing of potentially inappropriate medications in patients on hemodialysis. American Journal of Health-System Pharmacy 79:Supplement_4, pages S128-S135.
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Deborah Dowell, Kathleen R. Ragan, Christopher M. Jones, Grant T. Baldwin & Roger Chou. (2022) CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 . MMWR. Recommendations and Reports 71:3, pages 1-95.
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Julie C. Lauffenburger, Maxwell D. Coll, Erin Kim, Ted Robertson, Rebecca Oran, Nancy Haff, Kaitlin Hanken, Jerry Avorn & Niteesh K. Choudhry. (2022) Prescribing decision making by medical residents on night shifts: A qualitative study. Medical Education 56:10, pages 1032-1041.
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Glenna S. Brewster, Barbara Riegel & Philip R. Gehrman. (2022) Insomnia in the Older Adult. Sleep Medicine Clinics 17:2, pages 233-239.
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Barbara Farrell. (2022) Part I: Interactive case: Rational deprescribing of benzodiazepine receptor agonists for insomnia. JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 5:3, pages 370-376.
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François-Xavier Sibille, Anne Spinewine, Lorène Zerah, Laurentine Maljean, Didier Schoevaerdts & Marie de Saint-Hubert. (2022) Current practice in benzodiazepine receptor agonists deprescribing on acute geriatric wards: a cohort study. BMC Geriatrics 22:1.
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Allison R. Thompson, Catherine S. Kim, Grace E. Kim, Michelle S. Keller, Zachary A. Marcum & Nicole J. Brandt. (2022) Challenges and Successes of Global Deprescribing Networks: A Qualitative Key Informant Study. Journal of Gerontological Nursing 48:1, pages 7-14.
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Alistair J. Reid Finlayson, Jane Macoubrie, Christy Huff, D.E. Foster & Peter R. Martin. (2022) Experiences with benzodiazepine use, tapering, and discontinuation: an Internet survey. Therapeutic Advances in Psychopharmacology 12, pages 204512532210823.
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Michael Soyka. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 494 509 .
Hana Vankova, Iva Holmerova & Ladislav Volicer. (2021) Geriatric Depression and Inappropriate Medication: Benefits of Interprofessional Team Cooperation in Nursing Homes. International Journal of Environmental Research and Public Health 18:23, pages 12438.
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Jaden Brandt, Donica Janzen, Silvia Alessi-Severini, Alexander Singer, Dan Chateau, Murray Enns & Christine Leong. (2021) Risk of long-term benzodiazepine and Z-drug use following the first prescription among community-dwelling adults with anxiety/mood and sleep disorders: a retrospective cohort study. BMJ Open 11:11, pages e046916.
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Mélinée Chapoutot, Laure Peter-Derex, Hélène Bastuji, Wendy Leslie, Benjamin Schoendorff, Raphael Heinzer, Francesca Siclari, Alain Nicolas, Patrick Lemoine, Susan Higgins, Alexia Bourgeois, Guillaume T. Vallet, Royce Anders, Marc Ounnoughene, Jessica Spencer, Francesca Meloni & Benjamin Putois. (2021) Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for the Discontinuation of Long-Term Benzodiazepine Use in Insomnia and Anxiety Disorders. International Journal of Environmental Research and Public Health 18:19, pages 10222.
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Michael Soyka. (2021) Missbrauch und Abhängigkeit von Benzodiazepinen und Z-Drugs. Nervenheilkunde 40:08, pages 636-647.
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Shelly L. Gray, Zizi Elsisi, Elizabeth A. Phelan & Joseph T. Hanlon. (2021) Interventions to Reduce Fall-Risk-Increasing Drug Use to Prevent Falls: A Narrative Review of Randomized Trials. Drugs & Aging 38:4, pages 301-309.
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Robert William Hoel, Ryan M. Giddings Connolly & Paul Y. Takahashi. (2021) Polypharmacy Management in Older Patients. Mayo Clinic Proceedings 96:1, pages 242-256.
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Mara Storto & Meera Balasubramaniam. 2021. Absolute Geriatric Psychiatry Review. Absolute Geriatric Psychiatry Review 259 269 .
Laura A. Hart, Elizabeth A. Phelan, Julia Y. Yi, Zachary A. Marcum & Shelly L. Gray. (2020) Use of Fall Risk–Increasing Drugs Around a Fall‐Related Injury in Older Adults: A Systematic Review. Journal of the American Geriatrics Society 68:6, pages 1334-1343.
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Jeffrey Gold. (2020) Approaches to managing benzodiazepines. Pharmacy Today 26:3, pages 41-54.
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Laura J Anderson, Jeffrey L Schnipper, Teryl K Nuckols, Rita Shane, Catherine Sarkisian, Michael M Le, Joshua M Pevnick, Carmel M Hughes, Cynthia A Jackevicius & Denis O’Mahony. (2019) A systematic overview of systematic reviews evaluating interventions addressing polypharmacy. American Journal of Health-System Pharmacy 76:21, pages 1777-1787.
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Roy R. Reeves & Arif Kamal. (2019) Complicated Withdrawal Phenomena During Benzodiazepine Cessation in Older Adults. Journal of Osteopathic Medicine 119:5, pages 327-331.
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Vera De Carlo, Benedetta Grancini, Matteo Vismara, Beatrice Benatti, Chiara Arici, Laura Cremaschi, Giovanna Cirnigliaro, Luca Degoni, Lucio Oldani, Carlotta Palazzo, Ira D. Glick, Caterina Viganò & Bernardo Dell'Osso. (2019) Exploring characteristics associated with first benzodiazepine prescription in patients with affective disorders and related diagnoses. Human Psychopharmacology: Clinical and Experimental 34:3, pages e2695.
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D. A. Sychev, A. V. Zhuchkov, O. V. Tereshchenko & D. V. Ivashchenko. (2019) Tapering (deprescribing) of benzodiazepine tranquilizers. Neurology, Neuropsychiatry, Psychosomatics 11:1, pages 89-95.
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Ritva Lähteenmäki, Pertti J. Neuvonen, Juha Puustinen, Tero Vahlberg, Markku Partinen, Ismo Räihä & Sirkka‐Liisa Kivelä. (2018) Withdrawal from long‐term use of zopiclone, zolpidem and temazepam may improve perceived sleep and quality of life in older adults with primary insomnia. Basic & Clinical Pharmacology & Toxicology 124:3, pages 330-340.
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. (2018) Take a multifaceted stepwise approach when deprescribing benzodiazepines in older patients. Drugs & Therapy Perspectives 35:2, pages 72-76.
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Stephanie L. Harrison, Monica Cations, Tiffany Jessop, Sarah N. Hilmer, Mouna Sawan & Henry Brodaty. (2018) Approaches to Deprescribing Psychotropic Medications for Changed Behaviours in Long-Term Care Residents Living with Dementia. Drugs & Aging 36:2, pages 125-136.
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Lisa M. Kalisch Ellett, Renly Lim, Nicole L. Pratt, Mhairi Kerr, Emmae N. Ramsay, Tammy V. LeBlanc, John D. Barratt & Elizabeth E. Roughead. (2018) Reducing hypnotic use in insomnia management among Australian veterans: results from repeated national interventions. BMC Health Services Research 18:1.
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Juha Puustinen, Ritva Lähteenmäki, Janne Nurminen, Tero Vahlberg, Pertti Aarnio, Markku Partinen, Ismo Räihä, Pertti J. Neuvonen & Sirkka-Liisa Kivelä. (2018) Long-term persistence of withdrawal of temazepam, zopiclone, and zolpidem in older adults: a 3-year follow-up study. BMC Geriatrics 18:1.
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François Naccache & Florence Vorspan. (2018) Stratégies de sevrage de benzodiazépines en ambulatoire. Revue de la littérature. La Presse Médicale 47:10, pages 899-912.
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Florence Vorspan, Thomas Barré, Antoine Pariente, François Montastruc & Marie Tournier. (2018) Faut-il limiter la durée des traitements par benzodiazépines ?. La Presse Médicale 47:10, pages 892-898.
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Marie-Michèle Tanguay Bernard, Mireille Luc, Jean-Daniel Carrier, Louise Fournier, Arnaud Duhoux, Elodie Côté, Olivier Lessard, Catherine Gibeault, Christian Bocti & Pasquale Roberge. (2018) Patterns of benzodiazepines use in primary care adults with anxiety disorders. Heliyon 4:7, pages e00688.
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Mina Kobayashi, Isa Okajima, Hajime Narisawa, Takashi Kikuchi, Kentaro Matsui, Ken Inada, Jun Ishigooka & Yuichi Inoue. (2018) Development of a new benzodiazepine hypnotics withdrawal symptom scale. Sleep and Biological Rhythms 16:3, pages 263-271.
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Brendan J. Ng, David G. Le Couteur & Sarah N. Hilmer. (2018) Deprescribing Benzodiazepines in Older Patients: Impact of Interventions Targeting Physicians, Pharmacists, and Patients. Drugs & Aging 35:6, pages 493-521.
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Glenna S. Brewster, Barbara Riegel & Philip R. Gehrman. (2018) Insomnia in the Older Adult. Sleep Medicine Clinics 13:1, pages 13-19.
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Gina C. Dobbs & Susanne A. Fogger. (2018) Opiate Dependence or Addiction?. Journal of Addictions Nursing 29:1, pages 57-61.
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Monica Martinez-Cengotitabengoa, Maria Jose Diaz-Gutierrez, Ariadna Besga, Cristina Bermúdez-Ampudia, Purificación López, Marta B. Rondon, Donna E. Stewart, Patricia Perez, Miguel Gutierrez & Ana Gonzalez-Pinto. (2018) Benzodiazepine prescriptions and falls in older men and women. Revista de Psiquiatría y Salud Mental (English Edition) 11:1, pages 12-18.
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Monica Martinez-Cengotitabengoa, Maria Jose Diaz-Gutierrez, Ariadna Besga, Cristina Bermúdez-Ampudia, Purificación López, Marta B. Rondon, Donna E. Stewart, Patricia Perez, Miguel Gutierrez & Ana Gonzalez-Pinto. (2018) Prescripción de benzodiacepinas y caídas en mujeres y hombres ancianos. Revista de Psiquiatría y Salud Mental 11:1, pages 12-18.
Crossref
Tilman Wetterling & Klaus Junghanns. (2017) Substance Abuse in Older Psychiatric Inpatients. SUCHT 63:2, pages 115-121.
Crossref
Dirk K. Wolter. (2017) Suchtpotenzial und andere Risiken von Benzodiazepinen und Z-Drugs im Alter. SUCHT 63:2, pages 81-97.
Crossref
Emily Reeve, Wade Thompson & Barbara Farrell. (2017) Deprescribing: A narrative review of the evidence and practical recommendations for recognizing opportunities and taking action. European Journal of Internal Medicine 38, pages 3-11.
Crossref
Dirk K. Wolter. (2017) Benzodiazepine absetzen im AlterDiscontinuation of benzodiazepines in old age. Zeitschrift für Gerontologie und Geriatrie 50:2, pages 115-122.
Crossref
David J. Kim & Srdjan S. Nedeljkovic. 2017. Pain Medicine. Pain Medicine 173 174 .
A.J.-P. Schwitzguébel, C. Benaïm, S. Carda, A.M. Torea Filgueira, R. Frischknecht & P.-A. Rapin. (2016) GABAergic drug use and global, cognitive, and motor functional outcomes after stroke. Annals of Physical and Rehabilitation Medicine 59:5-6, pages 320-325.
Crossref
Matej Markota, Teresa A. Rummans, John Michael Bostwick & Maria I. Lapid. (2016) Benzodiazepine Use in Older Adults: Dangers, Management, and Alternative Therapies. Mayo Clinic Proceedings 91:11, pages 1632-1639.
Crossref
Guillaume Airagnes, Antoine Pelissolo, Mélanie Lavallée, Martine Flament & Frédéric Limosin. (2016) Benzodiazepine Misuse in the Elderly: Risk Factors, Consequences, and Management. Current Psychiatry Reports 18:10.
Crossref
Paxton BachGeoffrey WaltonKanna HayashiM-J MilloyHuiru DongThomas KerrJulio MontanerEvan Wood. (2016) Benzodiazepine Use and Hepatitis C Seroconversion in a Cohort of Persons Who Inject Drugs. American Journal of Public Health 106:6, pages 1067-1072.
Crossref
Daniele Cristina Comino Naloto, Francine Cristiane Lopes, Silvio Barberato Filho, Luciane Cruz Lopes, Fernando de Sá Del Fiol & Cristiane de Cássia Bergamaschi. (2016) Prescrição de benzodiazepínicos para adultos e idosos de um ambulatório de saúde mental. Ciência & Saúde Coletiva 21:4, pages 1267-1276.
Crossref
Deborah Dowell, Tamara M. Haegerich & Roger Chou. (2016) CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR. Recommendations and Reports 65:1, pages 1-49.
Crossref
Vincenzo Arcoraci & Edoardo Spina. 2016. Pharmacovigilance in Psychiatry. Pharmacovigilance in Psychiatry 191 207 .
Angela Wright, Jacqueline Diebold, Jaskiran Otal, Carly Stoneman, Jonathan Wong, Christine Wallace & Mark Duffett. (2015) The Effect of Melatonin on Benzodiazepine Discontinuation and Sleep Quality in Adults Attempting to Discontinue Benzodiazepines: A Systematic Review and Meta-Analysis. Drugs & Aging 32:12, pages 1009-1018.
Crossref
Caterina Vicens Caldentey, Ermengol Sempere Verd?Francisca Fiol Gelabert. (2015) Estrategias para reducir el uso prolongado de benzodiacepinas. FMC - Formaci?n M?dica Continuada en Atenci?n Primaria 22:9, pages 510-518.
Crossref
Lamiae Grimaldi-Bensouda, Lucien Abenhaim, Jacques Massol, Didier Guillemot, Bernard Avouac, Gerard Duru, France Lert, Anne-Marie Magnier, Michel Rossignol, Frederic Rouillon & Bernard Begaud. (2015) Utilization of psychotropic drugs by patients consulting for sleeping disorders in homeopathic and conventional primary care settings: the EPI3 cohort study. Homeopathy 104:3, pages 170-175.
Crossref

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