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Editorial

Tamoxifen-induced non-alcoholic steatohepatitis: where are we now and where are we going?

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Pages 1-4 | Published online: 20 Dec 2006

Keep up to date with the latest research on this topic with citation updates for this article.

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Rachel P. L. van Swelm, Cornelis Kramers, Rosalinde Masereeuw & Frans G. M. Russel. (2014) Application of urine proteomics for biomarker discovery in drug-induced liver injury. Critical Reviews in Toxicology 44:10, pages 823-841.
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Articles from other publishers (35)

Dina G. Tiniakos, Quentin M. Anstee, Elizabeth M. Brunt & Alastair D. Burt. 2024. MacSween's Pathology of the Liver. MacSween's Pathology of the Liver 330 401 .
Alan L. Hutchison, Federica Tavaglione, Stefano Romeo & Michael Charlton. (2023) Endocrine aspects of metabolic dysfunction-associated steatotic liver disease (MASLD): Beyond insulin resistance. Journal of Hepatology 79:6, pages 1524-1541.
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Patrik Nasr, Cecilia Jönsson, Mattias Ekstedt & Stergios Kechagias. (2023) Non-metabolic causes of steatotic liver disease. Metabolism and Target Organ Damage 3:4.
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Cristiane A. Villela Nogueira & Nathalie Carvalho Leite. 2023. The Diabetes Textbook. The Diabetes Textbook 261 270 .
Xiaoyun Li, Jieting Tang & Yimin Mao. (2022) Incidence and risk factors of drug‐induced liver injury. Liver International.
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Dandan Song, Yingying Hu, Biyu Diao, Rongrong Miao, Baodan Zhang, Yangjun Cai, Hanqian Zeng, Yuru Zhang & Xiaoqu Hu. (2021) Effects of Tamoxifen vs. Toremifene on fatty liver development and lipid profiles in breast Cancer. BMC Cancer 21:1.
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Ting Hong, Yiyan Chen, Xiaoying Li & Yan Lu. (2021) The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD. Oxidative Medicine and Cellular Longevity 2021, pages 1-25.
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Naga P. ChalasaniHaripriya MaddurMark W. RussoRobert J. WongK. Rajender Reddy. (2021) ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. American Journal of Gastroenterology 116:5, pages 878-898.
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Joo-Ik Kim, Sae-Kwang Ku & Young-Joon Lee. (2020) Effect of 2.5 hr-interval single oral combination treatment of Gamisoyo-san with Tamoxifen on the pharmacokinetics profiles of Tamoxifen in rats. Journal of Korean Medicine 41:4, pages 1-11.
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Joo-Ik Kim, Sae-Kwang Ku & Lee surname. (2020) Effect of the Single Oral Combination Treatment of Tamoxifen with Gamisoyo-san on the Pharmacokinetics Profiles of Tamoxifen. Journal of Physiology & Pathology in Korean Medicine 34:4, pages 201-208.
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Jeong-Ju Yoo, Yong Seok Lim, Min Sung Kim, Bora Lee, Bo-Yeon Kim, Zisun Kim, Ji Eun Lee, Min Hee Lee, Sang Gyune Kim & Young Seok Kim. (2020) Risk of fatty liver after long-term use of tamoxifen in patients with breast cancer. PLOS ONE 15:7, pages e0236506.
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Bora Lee, Eun‐Ae Jung, Jeong‐Ju Yoo, Sang Gyune Kim, Cheon‐Beom Lee, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Baek Gyu Jun, Young Don Kim & Gab Jin Cheon. (2020) Prevalence, incidence and risk factors of tamoxifen‐related non‐alcoholic fatty liver disease: A systematic review and meta‐analysis. Liver International 40:6, pages 1344-1355.
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Jin-Ryul Hu, Tae-Woo Jang, Su-Jin Kang, Sae-Kwang Ku, Seong-Hun Choi & Young-Joon Lee. (2019) Effects of mixed formulation of tamoxifen and blue honeysuckle on the pharmacokinetics profiles of tamoxifen after single oral administration. Journal of Korean Medicine 40:4, pages 1-15.
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Cristiane A. Villela Nogueira & Nathalie Carvalho Leite. 2019. The Diabetes Textbook. The Diabetes Textbook 227 235 .
Junrong Cai, Bin Li, Jing Wang, Kaiyang Liu, Yuteng Zhang, Yunjun Liao & Feng Lu. (2018) Tamoxifen-Prefabricated Beige Adipose Tissue Improves Fat Graft Survival in Mice. Plastic & Reconstructive Surgery 141:4, pages 930-940.
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Dina G. Tiniakos, Quentin M. Anstee & Alastair D. Burt. 2018. Macsween's Pathology of the Liver. Macsween's Pathology of the Liver 308 371 .
Aderonke A. Akinkugbe, Gary D. Slade, A. Sidney Barritt, Stephen R. Cole, Steven Offenbacher, Astrid Petersmann, Thomas Kocher, Markus M. Lerch, Julia Mayerle, Henry Völzke, Gerardo Heiss & Birte Holtfreter. (2017) Periodontitis and Non-alcoholic Fatty Liver Disease, a population-based cohort investigation in the Study of Health in Pomerania. Journal of Clinical Periodontology 44:11, pages 1077-1087.
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Eun-A Ryu, 송창현, 최성훈, 한창현, 이영준, 구세광, 강수진 & Bong Hyo Lee. (2017) Effect of Gamiondam-tang (GMODT), a Polyherbal Formula on the Pharmacokinetics Profiles of Tamoxifen in Male SD Rats (2) - Single Oral Combination Treatment of Tamoxifen 50 mg/kg with GMODT 100 mg/kg with 2.5 hr-intervals -. Society of Preventive Korean Medicine 21:2, pages 127-137.
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Eun-A Ryu, Su-Jin Kang, Chang-Hyun Song, Bong-Hyo Lee, Seong-Hun Choi, Chang-Hyun Han, Young-Joon Lee & Sae-Kwang Ku. (2017) Effect of (GMODT), a Polyherbal Formula on the Pharmacokinetics Profiles of Tamoxifen in Male SD Rats. Journal of Korean Medicine 38:2, pages 61-72.
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Meiying Yan, Jingxuan Wang, Qijia Xuan, Tieying Dong, Juan He & Qingyuan Zhang. (2017) The Relationship Between Tamoxifen-associated Nonalcoholic Fatty Liver Disease and the Prognosis of Patients With Early-stage Breast Cancer. Clinical Breast Cancer 17:3, pages 195-203.
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Ali Moshiri, Ali Mohammad Sharifi & Ahmad Oryan. (2016) Current Knowledge, Drug-Based Therapeutic Options and Future Directions in Managing Osteoporosis. Clinical Reviews in Bone and Mineral Metabolism 15:1, pages 1-23.
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Min A Kwak, Soo Jin Park, Sung Hwan Park, Young Joon Lee & Sae Kwang Ku. (2016) Effect of Jaeumkanghwatang (JEKHT), a Polyherbal Formula on the Pharmacokinetics Profiles of Tamoxifen in Male SD Rats (1) - Single Oral Combination Treatment of Tamoxifen 50 mg/kg with JEKHT 100 mg/kg within 5 min -. Journal of Korean Medicine 37:2, pages 1-11.
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Ansoumane Kourouma, Hady Keita, Peng Duan, Chao Quan, Koikoi Kebe Bilivogui, Suqin Qi, Ndjiembi Adjonga Christiane, Aidogie Osamuyimen & Kedi Yang. (2015) Effects of 4-nonylphenol on oxidant/antioxidant balance system inducing hepatic steatosis in male rat. Toxicology Reports 2, pages 1423-1433.
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Ying Lin, Jianlun Liu, Xiaohua Zhang, Li Li, Rui Hu, Jian Liu, Yongchuan Deng, Dedian Chen, Yangbing Zhao, Shengrong Sun, Rong Ma, Ying Zhao, Jinping Liu, Yang Zhang, Xijing Wang, Yafen Li, Pingqing He, Enxiao Li, Zheli Xu, Yaqun Wu, Zhongsheng Tong, Xiaojia Wang, Tao Huang, Zhongxiao Liang, Shui Wang, Fengxi Su, Yunfei Lu, Helong Zhang, Guosheng Feng & Shenming Wang. (2014) A prospective, randomized study on hepatotoxicity of anastrozole compared with tamoxifen in women with breast cancer. Cancer Science 105:9, pages 1182-1188.
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Mariana P.C. Ribeiro, Armanda E. Santos & José B.A. Custódio. (2014) Mitochondria: The gateway for tamoxifen-induced liver injury. Toxicology 323, pages 10-18.
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Naga P Chalasani, Paul H Hayashi, Herbert L Bonkovsky, Victor J Navarro, William M Lee & Robert J Fontana. (2014) ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. American Journal of Gastroenterology 109:7, pages 950-966.
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L. Nikolaenko, Y. Jia, C. Wang, M. Diaz-Arjonilla, J. K. Yee, S. W. French, P. Y. Liu, S. Laurel, C. Chong, K. Lee, Y. Lue, W. N. P. Lee & R. S. Swerdloff. (2014) Testosterone Replacement Ameliorates Nonalcoholic Fatty Liver Disease in Castrated Male Rats. Endocrinology 155:2, pages 417-428.
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H. Nishizawa, G. Iguchi, A. Murawaki, H. Fukuoka, Y. Hayashi, H. Kaji, M. Yamamoto, K. Suda, M. Takahashi, Y. Seo, Y. Yano, R. Kitazawa, S. Kitazawa, M. Koga, Y. Okimura, K. Chihara & Y. Takahashi. (2012) Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy. European Journal of Endocrinology 167:1, pages 67-74.
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Zhonghui Li, Ming Yan, Zhoumin Li, Maika Vuki, Dan Wu, Fei Liu, Wenying Zhong, Luyong Zhang & Danke Xu. (2012) A multiplexed screening method for agonists and antagonists of the estrogen receptor protein. Analytical and Bioanalytical Chemistry 403:5, pages 1373-1384.
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Elizabeth M. Brunt, Brent A. Neuschwander-Tetri & Alastair D. Burt. 2012. MacSween's Pathology of the Liver. MacSween's Pathology of the Liver 293 359 .
Mohsen Akhondi-Meybodi, Mohammad-Reza Mortazavy-zadah, Zahra Hashemian & Mahdiah Moaiedi. (2011) Incidence and risk factors for non-alcoholic steatohepatitis in females treated with tamoxifen for breast cancer. Arab Journal of Gastroenterology 12:1, pages 34-36.
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Min-Ho Lee, Ji-Won Kim, Ju-Han Kim, Kyung-Sun Kang, Gu Kong & Mi-Ock Lee. (2010) Gene expression profiling of murine hepatic steatosis induced by tamoxifen. Toxicology Letters 199:3, pages 416-424.
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Curtis K. Argo & Stephen H. Caldwell. (2009) Epidemiology and Natural History of Non-Alcoholic Steatohepatitis. Clinics in Liver Disease 13:4, pages 511-531.
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Tom Saphner, Shirley Triest‐Robertson, Hailun Li & Paul Holzman. (2009) The association of nonalcoholic steatohepatitis and tamoxifen in patients with breast cancer. Cancer 115:14, pages 3189-3195.
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Ilaria Lenci, Mario Angelico, Giuseppe Tisone, Antonio Orlacchio, Giampiero Palmieri, Mariangela Pinci, Roberta Bombardieri & Paolo Curatolo. (2008) Massive hepatic angiomyolipoma in a young woman with tuberous sclerosis complex: Significant clinical improvement during tamoxifen treatment. Journal of Hepatology 48:6, pages 1026-1029.
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