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Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications

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Pages 835-850 | Published online: 28 Jul 2009

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Venkata K. Yellepeddi & Hamidreza Ghandehari. (2019) Pharmacokinetics of oral therapeutics delivered by dendrimer-based carriers. Expert Opinion on Drug Delivery 16:10, pages 1051-1061.
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Ali Serol Ertürk, Mustafa Ulvi Gürbüz & Metin Tülü. (2017) The effect of PAMAM dendrimer concentration, generation size and surface functional group on the aqueous solubility of candesartan cilexetil. Pharmaceutical Development and Technology 22:1, pages 111-121.
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Maryam Hosseini, Mostafa Haji-Fatahaliha, Farhad Jadidi-Niaragh, Jafar Majidi & Mehdi Yousefi. (2016) The use of nanoparticles as a promising therapeutic approach in cancer immunotherapy. Artificial Cells, Nanomedicine, and Biotechnology 44:4, pages 1051-1061.
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Venkata K. Yellepeddi & Hamidreza Ghandehari. (2016) Poly(amido amine) dendrimers in oral delivery. Tissue Barriers 4:2.
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Łukasz Uram, Magdalena Szuster, Aleksandra Filipowicz, Krzysztof Gargasz, Stanisław Wołowiec & Elżbieta Wałajtys-Rode. (2015) Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro. International Journal of Nanomedicine 10, pages 5647-5661.
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Rumiana Bakalova, Zhivko Zhelev, Daisuke Kokuryo, Lubomir Spasov, Ichio Aoki & Tsuneo Saga. (2011) Chemical nature and structure of organic coating of quantum dots is crucial for their application in imaging diagnostics. International Journal of Nanomedicine 6, pages 1719-1732.
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Andrew Gregory & Martina H Stenzel. (2011) The use of reversible addition fragmentation chain transfer polymerization for drug delivery systems. Expert Opinion on Drug Delivery 8:2, pages 237-269.
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Constantinos M Paleos, Dimitris Tsiourvas, Zili Sideratou & Leto-Aikaterini Tziveleka. (2010) Drug delivery using multifunctional dendrimers and hyperbranched polymers. Expert Opinion on Drug Delivery 7:12, pages 1387-1398.
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Natalia Wrońska, Aleksandra Felczak, Katarzyna Zawadzka, Martyna Poszepczyńska, Sylwia Różalska, Maria Bryszewska, Dietmar Appelhans & Katarzyna Lisowska. (2015) Poly(Propylene Imine) Dendrimers and Amoxicillin as Dual-Action Antibacterial Agents. Molecules 20:10, pages 19330-19342.
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Joaquim M. Oliveira, João F. Mano & Rui L. Reis. 2012. Biomimetic Approaches for Biomaterials Development. Biomimetic Approaches for Biomaterials Development 459 469 .
Sebastien Boridy, Ghareb M Soliman & Dusica Maysinger. (2012) Modulation of inflammatory signaling and cytokine release from microglia by celastrol incorporated into dendrimer nanocarriers. Nanomedicine 7:8, pages 1149-1165.
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Katie B. Ryan, Sam Maher, David J. Brayden & Caitriona M. O'driscoll*. 2012. Nanostructured Biomaterials for Overcoming Biological Barriers. Nanostructured Biomaterials for Overcoming Biological Barriers 63 90 .
Jaroslav Sebestik, Milan Reinis & Jan JezekJaroslav Šebestík, Milan Reiniš & Jan Ježek. 2012. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures 141 147 .
Jaroslav Sebestik, Milan Reinis & Jan JezekJaroslav Šebestík, Milan Reiniš & Jan Ježek. 2012. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures 131 140 .
Jaroslav Sebestik, Milan Reinis & Jan JezekJaroslav Šebestík, Milan Reiniš & Jan Ježek. 2012. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures 115 129 .
Jaroslav Sebestik, Milan Reinis & Jan JezekJaroslav Šebestík, Milan Reiniš & Jan Ježek. 2012. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures. Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures 111 114 .
Archana Swami, Jinjun Shi, Suresh Gadde, Alexander R. Votruba, Nagesh Kolishetti & Omid C. Farokhzad. 2012. Multifunctional Nanoparticles for Drug Delivery Applications. Multifunctional Nanoparticles for Drug Delivery Applications 9 29 .
Tina C Wan, Dilip K Tosh, Lili Du, Elizabeth T Gizewski, Kenneth A Jacobson & John A Auchampach. (2011) Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts. BMC Pharmacology 11:1.
Crossref
Shrinivas Venkataraman, James L. Hedrick, Zhan Yuin Ong, Chuan Yang, Pui Lai Rachel Ee, Paula T. Hammond & Yi Yan Yang. (2011) The effects of polymeric nanostructure shape on drug delivery. Advanced Drug Delivery Reviews 63:14-15, pages 1228-1246.
Crossref
Haijun Yu, Yu Nie, Christian Dohmen, Yunqiu Li & Ernst Wagner. (2011) Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry. Biomacromolecules 12:6, pages 2039-2047.
Crossref
Yuehua Zhang, Thommey P. Thomas, Kyung-Hoon Lee, Minghsin Li, Hong Zong, Ankur M. Desai, Alina Kotlyar, Baohua Huang, Mark M. Banaszak Holl & James R. BakerJr.Jr.. (2011) Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer–methotrexate conjugate as a potential anticancer agent. Bioorganic & Medicinal Chemistry 19:8, pages 2557-2564.
Crossref
Jaroslav Sebestik, Petr Niederhafner & Jan Jezek. (2010) Peptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications. Amino Acids 40:2, pages 301-370.
Crossref
Julia Morales-Sanfrutos, Alicia Megia-Fernandez, Fernando Hernandez-Mateo, Ma Dolores Giron-Gonzalez, Rafael Salto-Gonzalez & Francisco Santoyo-Gonzalez. (2011) Alkyl sulfonyl derivatized PAMAM-G2dendrimers as nonviral gene delivery vectors with improved transfection efficiencies. Org. Biomol. Chem. 9:3, pages 851-864.
Crossref
Kenneth A. Jacobson. (2010) GPCR ligand–dendrimer (GLiDe) conjugates: future smart drugs?. Trends in Pharmacological Sciences 31:12, pages 575-579.
Crossref
Didier Astruc, Elodie Boisselier & Cátia Ornelas. (2010) Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine. Chemical Reviews 110:4, pages 1857-1959.
Crossref
Timothy A. Johnson, Nathan A. Stasko, Jessica L. Matthews, Wayne E. Cascio, Ekhson L. Holmuhamedov, C. Bryce Johnson & Mark H. Schoenfisch. (2010) Reduced ischemia/reperfusion injury via glutathione-initiated nitric oxide-releasing dendrimers. Nitric Oxide 22:1, pages 30-36.
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