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Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease

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Pages 1393-1407 | Published online: 05 Oct 2012

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Kristina Lechner, Mahira Zeeshan, Maxi Noack, Hussain Ali, Markus F. Neurath & Benno Weigmann. (2022) Small but powerful: will nanoparticles be the future state‐of‐the‐art therapy for IBD?. Expert Opinion on Drug Delivery 19:3, pages 235-245.
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Hazem Choukaife, Salma Seyam, Batoul Alallam, Abd Almonem Doolaanea & Mulham Alfatama. (2022) Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment. International Journal of Nanomedicine 17, pages 3933-3966.
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Liucan Wang, Min Yu & Hua Yang. (2021) Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease. Journal of Inflammation Research 14, pages 1701-1716.
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Fengqian Chen, Qi Liu, Yang Xiong & Li Xu. (2021) Current Strategies and Potential Prospects of Nanomedicine-Mediated Therapy in Inflammatory Bowel Disease. International Journal of Nanomedicine 16, pages 4225-4237.
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Xiaomeng Tang, Meng Yang, Yongwei Gu, Liangdi Jiang, Yue Du & Jiyong Liu. (2021) Orally Deliverable Dual-Targeted Pellets for the Synergistic Treatment of Ulcerative Colitis. Drug Design, Development and Therapy 15, pages 4105-4123.
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Siwei Song, Hui Xia, Mengfei Guo, Sufei Wang, Shujing Zhang, Pei Ma & Yang Jin. (2021) Role of macrophage in nanomedicine-based disease treatment. Drug Delivery 28:1, pages 752-766.
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Qiubing Chen, Bo Xiao & Didier Merlin. (2017) Nanotherapeutics for the treatment of inflammatory bowel disease. Expert Review of Gastroenterology & Hepatology 11:6, pages 495-497.
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Lin Liu, WenDong Yao, YueFeng Rao, XiaoYang Lu & JianQing Gao. (2017) pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms. Drug Delivery 24:1, pages 569-581.
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Jian Guo, Xiaojing Jiang & Shuangying Gui. (2016) RNA interference-based nanosystems for inflammatory bowel disease therapy. International Journal of Nanomedicine 11, pages 5287-5310.
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Mingzhen Zhang, Emilie Viennois, Changlong Xu & Didier Merlin. (2016) Plant derived edible nanoparticles as a new therapeutic approach against diseases. Tissue Barriers 4:2.
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Fangyuan Wang, Qianqian Shan, Xiangwei Chang, Zhenbao Li & Shuangying Gui. (2021) Paeonol-loaded PLGA nanoparticles as an oral drug delivery system: Design, optimization and evaluation. International Journal of Pharmaceutics 602, pages 120617.
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Yamei Huang, Brandon S. B. Canup, Shuangquan Gou, Nanxi Chen, Fangyin Dai, Bo Xiao & Changming Li. (2021) Oral nanotherapeutics with enhanced mucus penetration and ROS-responsive drug release capacities for delivery of curcumin to colitis tissues. Journal of Materials Chemistry B 9:6, pages 1604-1615.
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Eden Mariam Jacob, Ankita Borah, Sindhu C Pillai & D. Sakthi Kumar. (2020) Inflammatory Bowel Disease: The Emergence of New Trends in Lifestyle and Nanomedicine as the Modern Tool for Pharmacotherapy. Nanomaterials 10:12, pages 2460.
Crossref
Patrycja Golińska & Magdalena Wypij. 2020. Nanobiotechnology in Diagnosis, Drug Delivery, and Treatment. Nanobiotechnology in Diagnosis, Drug Delivery, and Treatment 47 62 .
Dulari Jayawardena, Arivarasu N Anbazhagan, Shubha Priyamvada, Anoop Kumar, Seema Saksena, Hayat Onyuksel & Pradeep K Dudeja. (2020) Colonic delivery of vasoactive intestinal peptide nanomedicine alleviates colitis and shows promise as an oral capsule. Nanomedicine 15:25, pages 2459-2474.
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Yunyue Zhang, Maya Thanou & Driton Vllasaliu. (2020) Exploiting disease-induced changes for targeted oral delivery of biologics and nanomedicines in inflammatory bowel disease. European Journal of Pharmaceutics and Biopharmaceutics 155, pages 128-138.
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Yan Yan, Ying Sun, Pengchong Wang, Rui Zhang, Chuanchuan Huo, Tingting Gao, Chenghua Song, Jianfeng Xing & Yalin Dong. (2020) Mucoadhesive nanoparticles-based oral drug delivery systems enhance ameliorative effects of low molecular weight heparin on experimental colitis. Carbohydrate Polymers 246, pages 116660.
Crossref
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Crossref
Adrian H. Teruel, Isabel Gonzalez-Alvarez, Marival Bermejo, Virginia Merino, Maria Dolores Marcos, Felix Sancenon, Marta Gonzalez-Alvarez & Ramon Martinez-Mañez. (2020) New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy. International Journal of Molecular Sciences 21:18, pages 6502.
Crossref
Xin Li, Chao Lu, Yanyan Yang, Chaohui Yu & Yuefeng Rao. (2020) Site-specific targeted drug delivery systems for the treatment of inflammatory bowel disease. Biomedicine & Pharmacotherapy 129, pages 110486.
Crossref
Nabil A. Alhakamy, Osama A. A. Ahmed, Mallesh Kurakula, Giuseppe Caruso, Filippo Caraci, Hani Z. Asfour, Anas Alfarsi, Basma G. Eid, Amir I. Mohamed, Nabil K. Alruwaili, Wesam H. Abdulaal, Usama A. Fahmy, Hani A. Alhadrami, Basmah M. Eldakhakhny & Ashraf B. Abdel-Naim. (2020) Chitosan-Based Microparticles Enhance Ellagic Acid’s Colon Targeting and Proapoptotic Activity. Pharmaceutics 12:7, pages 652.
Crossref
Claudia Curcio, Antonio S. Greco, Salvatore Rizzo, Lorena Saitta, Teresa Musumeci, Barbara Ruozi & Rosario Pignatello. (2020) Development, Optimization and Characterization of Eudraguard®-Based Microparticles for Colon Delivery. Pharmaceuticals 13:6, pages 131.
Crossref
Prasad Minakshi, Rajesh Kumar, Mayukh Ghosh, Basanti Brar, Manju Barnela & Preeti Lakhani. (2020) Application of Polymeric Nano-Materials in Management of Inflammatory Bowel Disease. Current Topics in Medicinal Chemistry 20:11, pages 982-1008.
Crossref
Feng Wei, Yuhuang Lang, Qiang Shen, Lin Xu, Nuo Cheng, Yan Chu, Hongwei Lyu & Fengyuan Chen. (2020) Osteopontin-loaded PLGA nanoparticles enhance the intestinal mucosal barrier and alleviate inflammation via the NF-κB signaling pathway. Colloids and Surfaces B: Biointerfaces 190, pages 110952.
Crossref
Erazuliana Abd Kadir & Vuanghao Lim. 2020. Bioadhesives in Drug Delivery. Bioadhesives in Drug Delivery 123 145 .
Susan Hua. (2020) Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors. Frontiers in Pharmacology 11.
Crossref
Nabil A. Alhakamy, Usama A. Fahmy, Osama A. A. Ahmed, Giuseppe Caruso, Filippo Caraci, Hani Z. Asfour, Muhammed A. Bakhrebah, Mohammad N. Alomary, Wesam H. Abdulaal, Solomon Z. Okbazghi, Ashraf B. Abdel-Naim, Basma G. Eid, Hibah M. Aldawsari, Mallesh Kurakula & Amir I. Mohamed. (2020) Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity. Marine Drugs 18:4, pages 226.
Crossref
Xibao Tian, Jiali Gao, Meishuo Liu, Yuqin Lei, Fangjun Wang, Jin Chen, Peng Chu, Jiujiao Gao, Feida Long, Minzhi Liang, Xiangyu Long, Huiying Chu, Cuixia Liu, Xueliang Li, Qingxiang Sun, Guohui Li & Yongliang Yang. (2020) Small-Molecule Antagonist Targeting Exportin-1 via Rational Structure-Based Discovery. Journal of Medicinal Chemistry 63:8, pages 3881-3895.
Crossref
Xin Zhou, Yao Liu, Xianfeng Wang, Xiaomeng Li & Bo Xiao. (2020) Effect of particle size on the cellular uptake and anti-inflammatory activity of oral nanotherapeutics. Colloids and Surfaces B: Biointerfaces 187, pages 110880.
Crossref
Rakhi Chaudhary & Barkha Singhal. 2020. Intelligent Nanomaterials for Drug Delivery Applications. Intelligent Nanomaterials for Drug Delivery Applications 61 84 .
Muhammad Naeem, Uzma Azeem Awan, Fazli Subhan, Jiafu Cao, Shwe Phyu Hlaing, Juho Lee, Eunok Im, Yunjin Jung & Jin-Wook Yoo. (2020) Advances in colon-targeted nano-drug delivery systems: challenges and solutions. Archives of Pharmacal Research 43:1, pages 153-169.
Crossref
Nidhi Mishra, Samipta Singh, Priyanka Maurya, Raquibun Nisha & Shubhini A. Saraf. 2020. Nanoformulations in Human Health. Nanoformulations in Human Health 133 167 .
Xueqing Zhang, Ya Ma, Lijun Ma, Menghang Zu, Heliang Song & Bo Xiao. (2019) Oral administration of chondroitin sulfate-functionalized nanoparticles for colonic macrophage-targeted drug delivery. Carbohydrate Polymers 223, pages 115126.
Crossref
Ya Wu, Minghui Sun, Dan Wang, Genyun Li, Jiangeng Huang, Songwei Tan, Lin Bao, Qian Li, Gao Li & Luqin Si. (2019) A PepT1 mediated medicinal nano-system for targeted delivery of cyclosporine A to alleviate acute severe ulcerative colitis. Biomaterials Science 7:10, pages 4299-4309.
Crossref
Milad Reda Qelliny, Usama Farghaly Aly, Omar Helmy Elgarhy & Khaled Aly Khaled. (2019) Budesonide-Loaded Eudragit S 100 Nanocapsules for the Treatment of Acetic Acid-Induced Colitis in Animal Model. AAPS PharmSciTech 20:6.
Crossref
Xin Zhou, Yao Liu, Yamei Huang, Ya Ma, Jun Lv & Bo Xiao. (2019) Mucus-penetrating polymeric nanoparticles for oral delivery of curcumin to inflamed colon tissue. Journal of Drug Delivery Science and Technology 52, pages 157-164.
Crossref
Shuangquan Gou, Yamei Huang, Ying Wan, Ya Ma, Xin Zhou, Xiaoling Tong, Jin Huang, Yuejun Kang, Guoqing Pan, Fangyin Dai & Bo Xiao. (2019) Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis. Biomaterials 212, pages 39-54.
Crossref
Xin Zhou, Qiubing Chen, Ya Ma, Yamei Huang, Shuangquan Gou & Bo Xiao. (2019) Porous Polymeric Microparticles as an Oral Drug Platform for Effective Ulcerative Colitis Treatment. Journal of Pharmaceutical Sciences 108:7, pages 2238-2242.
Crossref
Ritesh M. Pabari, Clara Mattu, Sailesh Partheeban, Aqeel Almarhoon, Monica Boffito, Gianluca Ciardelli & Zebunnissa Ramtoola. (2019) Novel polyurethane-based nanoparticles of infliximab to reduce inflammation in an in-vitro intestinal epithelial barrier model. International Journal of Pharmaceutics 565, pages 533-542.
Crossref
Panpan Ma, Xiaoying Si, Qiubing Chen, Lijun Ma, Meili Hou, Zhigang Xu, Yuejun Kang, Jianglin Wang & Bo Xiao. (2019) Oral Drug Delivery Systems for Ulcerative Colitis Therapy: A Comparative Study with Microparticles and Nanoparticles. Current Cancer Drug Targets 19:4, pages 304-311.
Crossref
Xiaoyu Wang, Mingzhen Zhang, Shireen R.L. Flores, Regina R. Woloshun, Chunhua Yang, Liangjie Yin, Ping Xiang, Xiaodong Xu, Michael D. Garrick, Sadasivan Vidyasagar, Didier Merlin & James F. Collins. (2019) Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis. Molecular Therapy 27:3, pages 493-506.
Crossref
Mahira Zeeshan, Hussain Ali, Salman Khan, Saeed Ahmad Khan & Benno Weigmann. (2019) Advances in orally-delivered pH-sensitive nanocarrier systems; an optimistic approach for the treatment of inflammatory bowel disease. International Journal of Pharmaceutics 558, pages 201-214.
Crossref
Qiubing Chen, Shuangquan Gou, Panpan Ma, Heliang Song, Xin Zhou, Yamei Huang, Moon Kwon Han, Ying Wan, Yuejun Kang & Bo Xiao. (2019) Oral administration of colitis tissue-accumulating porous nanoparticles for ulcerative colitis therapy. International Journal of Pharmaceutics 557, pages 135-144.
Crossref
Nafisah Musa & Tin Wui Wong. 2019. Functional Chitosan. Functional Chitosan 135 161 .
Bo Xiao, Qiubing Chen, Zhan Zhang, Lixin Wang, Yuejun Kang, Timothy Denning & Didier Merlin. (2018) TNFα gene silencing mediated by orally targeted nanoparticles combined with interleukin-22 for synergistic combination therapy of ulcerative colitis. Journal of Controlled Release 287, pages 235-246.
Crossref
Qiubing Chen, Shuangquan Gou, Yamei Huang, Xin Zhou, Qian Li, Moon Kwon Han, Yuejun Kang & Bo Xiao. (2018) Facile fabrication of bowl-shaped microparticles for oral curcumin delivery to ulcerative colitis tissue. Colloids and Surfaces B: Biointerfaces 169, pages 92-98.
Crossref
Andreia Almeida, Helena Macedo, José das Neves & Bruno Sarmento. 2018. Stimuli-responsive Drug Delivery Systems. Stimuli-responsive Drug Delivery Systems 83 108 .
Bo Xiao, Emilie Viennois, Qiubing Chen, Lixin Wang, Moon Kwon Han, Yuchen Zhang, Zhan Zhang, Yuejun Kang, Ying Wan & Didier Merlin. (2018) Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer. ACS Nano 12:6, pages 5253-5265.
Crossref
Mingzhen Zhang & Didier Merlin. (2018) Nanoparticle-Based Oral Drug Delivery Systems Targeting the Colon for Treatment of Ulcerative Colitis. Inflammatory Bowel Diseases 24:7, pages 1401-1415.
Crossref
Xianpeng Shi, Yan Yan, Pengchong Wang, Ying Sun, Di Zhang, Yamin Zou, Sasa Hu, Lu Zhang, Jianfeng Xing & Yalin Dong. (2018) In vitro and in vivo study of pH-sensitive and colon-targeting P(LE-IA-MEG) hydrogel microspheres used for ulcerative colitis therapy. European Journal of Pharmaceutics and Biopharmaceutics 122, pages 70-77.
Crossref
Vijay Kothari, Chinmayi Joshi, Pooja Patel, Deepa Shahi, Charmi Mehta, Bhumika Prajapati, Sweta Patel, Dipeeka Mandaliya & Sriram Seshadri. 2018. Design of Nanostructures for Versatile Therapeutic Applications. Design of Nanostructures for Versatile Therapeutic Applications 325 377 .
Sufeng Zhang, Robert Langer & Giovanni Traverso. (2017) Nanoparticulate drug delivery systems targeting inflammation for treatment of inflammatory bowel disease. Nano Today 16, pages 82-96.
Crossref
Ugurlu Timucin. (2017) Mini Tablets: A Short Review-Revision. Open Journal of Chemistry, pages 012-022.
Crossref
Bo Xiao, Zhigang Xu, Emilie Viennois, Yuchen Zhang, Zhan Zhang, Mingzhen Zhang, Moon Kwon Han, Yuejun Kang & Didier Merlin. (2017) Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. Molecular Therapy 25:7, pages 1628-1640.
Crossref
Qiubing Chen, Xiaoying Si, Lijun Ma, Panpan Ma, Meili Hou, Shuang Bai, Xiaoshuai Wu, Ying Wan, Bo Xiao & Didier Merlin. (2017) Oral delivery of curcumin via porous polymeric nanoparticles for effective ulcerative colitis therapy. Journal of Materials Chemistry B 5:29, pages 5881-5891.
Crossref
Long Binh Vong & Yukio Nagasaki. 2017. Advances in Bioinspired and Biomedical Materials Volume 2. Advances in Bioinspired and Biomedical Materials Volume 2 47 67 .
Vipul Yadav, Felipe Varum, Roberto Bravo, Esther Furrer, Daniela Bojic & Abdul W. Basit. (2016) Inflammatory bowel disease: exploring gut pathophysiology for novel therapeutic targets. Translational Research 176, pages 38-68.
Crossref
Qixiong Zhang, Hui Tao, Yongyao Lin, Ying Hu, Huijie An, Dinglin Zhang, Shibin Feng, Houyuan Hu, Ruibing Wang, Xiaohui Li & Jianxiang Zhang. (2016) A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease. Biomaterials 105, pages 206-221.
Crossref
Bo Xiao, Panpan Ma, Emilie Viennois & Didier Merlin. (2016) Urocanic acid-modified chitosan nanoparticles can confer anti-inflammatory effect by delivering CD98 siRNA to macrophages. Colloids and Surfaces B: Biointerfaces 143, pages 186-193.
Crossref
Lei Lu, Gaoxian Chen, Yuanyuan Qiu, Mingwang Li, Dianhua Liu, Dehui Hu, Xiajing Gu & Zeyu Xiao. (2016) Nanoparticle-based oral delivery systems for colon targeting: principles and design strategies. Science Bulletin 61:9, pages 670-681.
Crossref
Jennifer M. Knipe, Laura E. Strong & Nicholas A. Peppas. (2016) Enzyme- and pH-Responsive Microencapsulated Nanogels for Oral Delivery of siRNA to Induce TNF-α Knockdown in the Intestine. Biomacromolecules 17:3, pages 788-797.
Crossref
Xiao-Ying Si, Didier Merlin & Bo Xiao. (2016) Recent advances in orally administered cell-specific nanotherapeutics for inflammatory bowel disease. World Journal of Gastroenterology 22:34, pages 7718.
Crossref
Franco Alhaique, Tommasina Coviello & Pietro Matricardi. 2015. Polysaccharide Hydrogels. Polysaccharide Hydrogels 1 37 .
Bo Xiao, Xiaoying Si, Mingzhen Zhang & Didier Merlin. (2015) Oral administration of pH-sensitive curcumin-loaded microparticles for ulcerative colitis therapy. Colloids and Surfaces B: Biointerfaces 135, pages 379-385.
Crossref
Shahriar Sharifi, Hajar Seyednejad, Sophie Laurent, Fatemeh Atyabi, Amir Ata Saei & Morteza Mahmoudi. (2015) Superparamagnetic iron oxide nanoparticles for in vivo molecular and cellular imaging . Contrast Media & Molecular Imaging 10:5, pages 329-355.
Crossref
Susan Hua, Ellen Marks, Jennifer J. Schneider & Simon Keely. (2015) Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: Selective targeting to diseased versus healthy tissue. Nanomedicine: Nanotechnology, Biology and Medicine 11:5, pages 1117-1132.
Crossref
Bo Xiao, Hamed Laroui, Emilie Viennois, Saravanan Ayyadurai, Moiz A. Charania, Yuchen Zhang, Zhan Zhang, Mark T. Baker, Benyue Zhang, Andrew T. Gewirtz & Didier Merlin. (2014) Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice. Gastroenterology 146:5, pages 1289-1300.e19.
Crossref
Richard d'Arcy & Nicola Tirelli. (2014) Fishing for fire: strategies for biological targeting and criteria for material design in anti‐inflammatory therapies. Polymers for Advanced Technologies 25:5, pages 478-498.
Crossref
Ole Haagen Nielsen. (2014) New Strategies for Treatment of Inflammatory Bowel Disease. Frontiers in Medicine 1.
Crossref
Bo Xiao, Yang Yang, Emilie Viennois, Yuchen Zhang, Saravanan Ayyadurai, Mark T. Baker, Hamed Laroui & Didier Merlin. (2014) Glycoprotein CD98 as a receptor for colitis-targeted delivery of nanoparticles. Journal of Materials Chemistry B 2:11, pages 1499.
Crossref
Kitae Ryu & Tae-il Kim. (2013) Therapeutic gene delivery using bioreducible polymers. Archives of Pharmacal Research 37:1, pages 31-42.
Crossref
Bo Xiao, Hamed Laroui, Saravanan Ayyadurai, Emilie Viennois, Moiz A. Charania, Yuchen Zhang & Didier Merlin. (2013) Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy. Biomaterials 34:30, pages 7471-7482.
Crossref
F. Talaei, F. Atyabi, M. Azhdarzadeh, R. Dinarvand & A. Saadatzadeh. (2013) Overcoming therapeutic obstacles in inflammatory bowel diseases: A comprehensive review on novel drug delivery strategies. European Journal of Pharmaceutical Sciences 49:4, pages 712-722.
Crossref
Juan F. Marquez Ruiz, Kinga Kedziora, Maria Pigott, Brian Keogh, Henry Windle, Jason Gavin, Dermot P. Kelleher & John F. Gilmer. (2013) A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib. Bioorganic & Medicinal Chemistry Letters 23:6, pages 1693-1698.
Crossref

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