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Strategies for delivering local anesthetics to the skin: focus on liposomes, solid lipid nanoparticles, hydrogels and patches

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Pages 1551-1563 | Published online: 13 Aug 2013

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He Ma, Zhenxiang Pan, Bingjie Lai, Chunfang Zan & He Liu. (2023) Recent Research Advances in Nano-Based Drug Delivery Systems for Local Anesthetics. Drug Design, Development and Therapy 17, pages 2639-2655.
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Tao Jiang, Shuangshuang Ma, Yangyang Shen, Yuwen Li, Ruirui Pan & Huaixin Xing. (2021) Topical anesthetic and pain relief using penetration enhancer and transcriptional transactivator peptide multi-decorated nanostructured lipid carriers. Drug Delivery 28:1, pages 478-486.
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Rong-Qin Qi, Wei Liu, Duan-Yu Wang, Fan-Qing Meng, Hong-Ying Wang & Hai-Yan Qi. (2021) Development of local anesthetic drug delivery system by administration of organo-silica nanoformulations under ultrasound stimuli: in vitro and in vivo investigations. Drug Delivery 28:1, pages 54-62.
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Bushra T ALQuadeib, Eram KD Eltahir & Modhi F Alagili. (2020) The Oral Administration of Lidocaine HCl Biodegradable Microspheres: Formulation and Optimization. International Journal of Nanomedicine 15, pages 857-869.
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Xiaomin Zhang, Minyan Dang, Wenzhi Zhang, Yan Lei & Wentao Zhou. (2020) Sustained delivery of prilocaine and lidocaine using depot microemulsion system: in vitro, ex vivo and in vivo animal studies. Drug Development and Industrial Pharmacy 46:2, pages 264-271.
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Daniele Ribeiro de Araújo, Lígia Nunes de Morais Ribeiro & Eneida de Paula. (2019) Lipid-based carriers for the delivery of local anesthetics. Expert Opinion on Drug Delivery 16:7, pages 701-714.
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Chuanyu Chen & Peijun You. (2017) A novel local anesthetic system: transcriptional transactivator peptide-decorated nanocarriers for skin delivery of ropivacaine. Drug Design, Development and Therapy 11, pages 1941-1949.
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Michelle Franz-Montan, Lígia Nunes de Morais Ribeiro, Maria Cristina Volpato, Cintia Maria Saia Cereda, Francisco Carlos Groppo, Giovana Randomille Tofoli, Daniele Ribeiro de Araújo, Patrizia Santi, Cristina Padula & Eneida de Paula. (2017) Recent advances and perspectives in topical oral anesthesia. Expert Opinion on Drug Delivery 14:5, pages 673-684.
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Li-Hua Peng, Wei Wei, Ying-Hui Shan, Yee-Song Chong, Lian Yu & Jian-Qing Gao. (2017) Sustained release of piroxicam from solid lipid nanoparticle as an effective anti-inflammatory therapeutics in vivo. Drug Development and Industrial Pharmacy 43:1, pages 55-66.
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Laizhu Zhang, Jianguo Wang, Huimin Chi & Shilei Wang. (2016) Local anesthetic lidocaine delivery system: chitosan and hyaluronic acid-modified layer-by-layer lipid nanoparticles. Drug Delivery 23:9, pages 3529-3537.
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Jianguo Wang, Laizhu Zhang, Huimin Chi & Shilei Wang. (2016) An alternative choice of lidocaine-loaded liposomes: lidocaine-loaded lipid–polymer hybrid nanoparticles for local anesthetic therapy. Drug Delivery 23:4, pages 1254-1260.
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Gang Wang, JunJie Wang, Wei Wu, Shing Shun Tony To, HuaFu Zhao & Jing Wang. (2015) Advances in lipid-based drug delivery: enhancing efficiency for hydrophobic drugs. Expert Opinion on Drug Delivery 12:9, pages 1475-1499.
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