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Severin Mairinger, Irene Hernández-Lozano, Markus Zeitlinger, Carsten Ehrhardt & Oliver Langer. (2022) Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition. Expert Opinion on Drug Delivery 19:12, pages 1561-1575.
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Articles from other publishers (43)
. (2023) Abstracts from The International Society for Aerosols in Medicine. Journal of Aerosol Medicine and Pulmonary Drug Delivery.
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Severin Mairinger, Irene Hernández-Lozano, Lena Zachhuber, Thomas Filip, Mathilde Löbsch, Markus Zeitlinger, Marcus Hacker, Carsten Ehrhardt & Oliver Langer. (2023) Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats. European Journal of Pharmaceutical Sciences 184, pages 106414.
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Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Mathilde Löbsch, Johann Stanek, Markus Zeitlinger, Marcus Hacker, Nicolas Tournier, Thomas Wanek, Carsten Ehrhardt & Oliver Langer. (2023) Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats. European Journal of Pharmaceutical Sciences 183, pages 106404.
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Johannes A. Sake, Mohammed Ali Selo, Lyubomyr Burtnyak, Henriette E. Dähnhardt, Camelia Helbet, Severin Mairinger, Oliver Langer, Vincent P. Kelly & Carsten Ehrhardt. (2023) Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models. European Journal of Pharmaceutical Sciences 181, pages 106364.
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Gergely Gyimesi & Matthias A. Hediger. (2023) Transporter-Mediated Drug Delivery. Molecules 28:3, pages 1151.
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Rossana Visigalli, Bianca Maria Rotoli, Francesca Ferrari, Maria Di Lascia, Benedetta Riccardi, Paola Puccini, Valeria Dall’Asta & Amelia Barilli. (2022) Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells. Biomolecules 12:9, pages 1260.
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Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Michael Sauberer, Mathilde Löbsch, Johann Stanek, Thomas Wanek, Johannes A. Sake, Thomas Pekar, Carsten Ehrhardt & Oliver Langer. (2022) Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats. Journal of Controlled Release 349, pages 109-117.
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Michael Wölfl-Duchek, Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Viktoria Zoufal, Mathilde Löbsch, Johann Stanek, Claudia Kuntner, Thomas Wanek, Martin Bauer, Jens Pahnke & Oliver Langer. (2022) Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice. International Journal of Molecular Sciences 23:12, pages 6514.
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Rejoice Thubelihle Ndebele, Qing Yao, Yan-Nan Shi, Yuan-Yuan Zhai, He-Lin Xu, Cui-Tao Lu & Ying-Zheng Zhao. (2022) Progress in the Application of Nano- and Micro-based Drug Delivery Systems in Pulmonary Drug Delivery. BIO Integration 3:2, pages 71-83.
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Irene Hernández-Lozano, Severin Mairinger, Thomas Filip, Michael Sauberer, Thomas Wanek, Johann Stanek, Johannes A. Sake, Thomas Pekar, Carsten Ehrhardt & Oliver Langer. (2022) PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats. Journal of Controlled Release 342, pages 44-52.
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Mohammed Ali Selo, Johannes A. Sake, Kwang-Jin Kim & Carsten Ehrhardt. (2021) In vitro and ex vivo models in inhalation biopharmaceutical research — advances, challenges and future perspectives. Advanced Drug Delivery Reviews 177, pages 113862.
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Astrid Bacle, Guillaume Bouzillé, Arnaud Bruyère, Marc Cuggia, Olivier Fardel & Pascal Le Corre. (2021) Drivers of absolute systemic bioavailability after oral pulmonary inhalation in humans. European Journal of Pharmaceutics and Biopharmaceutics 164, pages 36-53.
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Jenny P. Nguyen, Yechan Kim, Quynh Cao & Jeremy A. Hirota. (2021) Interactions between ABCC4/MRP4 and ABCC7/CFTR in human airway epithelial cells in lung health and disease. The International Journal of Biochemistry & Cell Biology 133, pages 105936.
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Zachary Enlo-Scott, Magda Swedrowska & Ben Forbes. 2021. Inhaled Medicines. Inhaled Medicines
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Mohammed Ali Selo, Johannes A. Sake, Carsten Ehrhardt & Johanna J. Salomon. (2020) Organic Cation Transporters in the Lung—Current and Emerging (Patho)Physiological and Pharmacological Concepts. International Journal of Molecular Sciences 21:23, pages 9168.
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Severin Mairinger, Johannes A. Sake, Irene Hernández Lozano, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Carsten Ehrhardt & Oliver Langer. (2020) Assessing the Activity of Multidrug Resistance–Associated Protein 1 at the Lung Epithelial Barrier. Journal of Nuclear Medicine 61:11, pages 1650-1657.
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Aylin Cidem, Peta Bradbury, Daniela Traini & Hui Xin Ong. (2020) Modifying and Integrating in vitro and ex vivo Respiratory Models for Inhalation Drug Screening. Frontiers in Bioengineering and Biotechnology 8.
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Mohammed Ali Selo, Anne-Sophie Delmas, Lisa Springer, Viktoria Zoufal, Johannes A. Sake, Caoimhe G. Clerkin, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr, Sabrina Nickel, Oliver Langer & Carsten Ehrhardt. (2020) Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cells in vitro. Frontiers in Bioengineering and Biotechnology 8.
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Nadica Sibinovska, Simon Žakelj, Robert Roškar & Katja Kristan. (2020) Suitability and functional characterization of two Calu-3 cell models for prediction of drug permeability across the airway epithelial barrier. International Journal of Pharmaceutics 585, pages 119484.
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Bianca Rotoli, Amelia Barilli, Rossana Visigalli, Francesca Ferrari, Caterina Frati, Costanza Lagrasta, Maria Di Lascia, Benedetta Riccardi, Paola Puccini & Valeria Dall’Asta. (2020) Characterization of ABC Transporters in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium. International Journal of Molecular Sciences 21:9, pages 3190.
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Johanna J. Salomon, Julia C. Gausterer, Mohammed Ali Selo, Ken-ichi Hosoya, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr & Carsten Ehrhardt. (2019) OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro. Pharmaceutics 11:8, pages 396.
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Markus Krohn, Viktoria Zoufal, Severin Mairinger, Thomas Wanek, Kristin Paarmann, Thomas Brüning, Ivan Eiriz, Mirjam Brackhan, Oliver Langer & Jens Pahnke. (2019)
Generation and Characterization of an
Abcc1
Humanized Mouse Model (
hABCC1
flx/flx
) with Knockout Capability
. Molecular Pharmacology 96:2, pages 138-147.
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Clément Mercier, Elodie Jacqueroux, Zhiguo He, Sophie Hodin, Samuel Constant, Nathalie Perek, Delphine Boudard & Xavier Delavenne. (2019) Pharmacological characterization of the 3D MucilAir™ nasal model. European Journal of Pharmaceutics and Biopharmaceutics 139, pages 186-196.
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Viktoria Zoufal, Severin Mairinger, Markus Krohn, Thomas Wanek, Thomas Filip, Michael Sauberer, Johann Stanek, Alexander Traxl, John D. Schuetz, Claudia Kuntner, Jens Pahnke & Oliver Langer. (2018) Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice. Molecular Imaging and Biology 21:2, pages 306-316.
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Nicole Schneider-Daum, Marius Hittinger, Xabier Murgia & Claus-Michael Lehr. 2019. Biological Responses to Nanoscale Particles. Biological Responses to Nanoscale Particles
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Nicolas Tournier, Bruno Stieger & Oliver Langer. (2018) Imaging techniques to study drug transporter function in vivo. Pharmacology & Therapeutics 189, pages 104-122.
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Lilian Henriques do Amaral, Flavia Almada do Carmo, Maria Inês Amaro, Valeria Pereira de Sousa, Luiz Claudio Rodrigues Pereira da Silva, Gabriella Silva de Almeida, Carlos Rangel Rodrigues, Anne Marie Healy & Lucio Mendes Cabral. (2018) Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods. AAPS PharmSciTech 19:6, pages 2687-2699.
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Peta Bradbury, Daniela Traini, Alaina J. Ammit, Paul M. Young & Hui Xin Ong. (2018) Repurposing of statins via inhalation to treat lung inflammatory conditions. Advanced Drug Delivery Reviews 133, pages 93-106.
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Clément Mercier, Sophie Hodin, Zhiguo He, Nathalie Perek & Xavier Delavenne. (2018) Pharmacological Characterization of the RPMI 2650 Model as a Relevant Tool for Assessing the Permeability of Intranasal Drugs. Molecular Pharmaceutics 15:6, pages 2246-2256.
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Siti N. Nurbaeti, Jean-Christophe Olivier, Christophe Adier, Sandrine Marchand, William Couet & Julien Brillault. (2018) Active Mediated Transport of Chloramphenicol and Thiamphenicol in a Calu-3 Lung Epithelial Cell Model. Journal of Pharmaceutical Sciences 107:4, pages 1178-1184.
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Marc Le Vée, Elodie Jouan & Olivier Fardel. (2018) Carrier-mediated uptake of clonidine in cultured human lung cells. Naunyn-Schmiedeberg's Archives of Pharmacology 391:4, pages 361-369.
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Per Bäckman, Sumit Arora, William Couet, Ben Forbes, Wilbur de Kruijf & Amrit Paudel. (2018) Advances in experimental and mechanistic computational models to understand pulmonary exposure to inhaled drugs. European Journal of Pharmaceutical Sciences 113, pages 41-52.
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Nicolas Grégoire, Vincent Aranzana-Climent, Sophie Magréault, Sandrine Marchand & William Couet. (2017) Clinical Pharmacokinetics and Pharmacodynamics of Colistin. Clinical Pharmacokinetics 56:12, pages 1441-1460.
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Carsten Ehrhardt. (2017) Inhalation Biopharmaceutics: Progress Towards Comprehending the Fate of Inhaled Medicines. Pharmaceutical Research 34:12, pages 2451-2453.
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Hovhannes J. Gukasyan, Tomomi Uchiyama, Kwang-Jin Kim, Carsten Ehrhardt, Sharon K. Wu, Zea Borok, Edward D. Crandall & Vincent H.L. Lee. (2017) Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2. Pharmaceutical Research 34:12, pages 2488-2497.
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Sabrina Nickel, Mohammed Ali Selo, Juliane Fallack, Caoimhe G. Clerkin, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr & Carsten Ehrhardt. (2017) Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro. Pharmaceutical Research 34:12, pages 2477-2487.
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Shahid Sukhbir Kaur. (2017) Pulmonary drug delivery system: newer patents. Pharmaceutical Patent Analyst 6:5, pages 225-244.
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Carsten Ehrhardt, Per Bäckman, William Couet, Chris Edwards, Ben Forbes, Markus Fridén, Mark Gumbleton, Ken-Ichi Hosoya, Yukio Kato, Takeo Nakanishi, Mikihisa Takano, Tetsuya Terasaki & Ryoko Yumoto. (2017) Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs. Journal of Pharmaceutical Sciences 106:9, pages 2234-2244.
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Manali Mukherjee, E. Cingolani, D.I. Pritchard & C. Bosquillon. (2017) Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – Impact on salbutamol transport. European Journal of Pharmaceutical Sciences 106, pages 62-70.
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Anne M. Dolberg & Stephan Reichl. (2017) Activity of Multidrug Resistance-Associated Proteins 1–5 (MRP1–5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate. Molecular Pharmaceutics 14:5, pages 1577-1590.
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Ayşe UfukFrauke AssmusLaura FrancisJonathan PlumbValeriu Damian, Michael Gertz, J. Brian HoustonAleksandra Galetin. (2017)
In Vitro
and
in Silico
Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages
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Erica Bäckström, Elin Boger, Anders Lundqvist, Margareta Hammarlund-Udenaes & Markus Fridén. (2016) Lung Retention by Lysosomal Trapping of Inhaled Drugs Can Be Predicted In Vitro With Lung Slices. Journal of Pharmaceutical Sciences 105:11, pages 3432-3439.
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Michele Pozzoli, Hui Xin Ong, Lucy Morgan, Maria Sukkar, Daniela Traini, Paul M. Young & Fabio Sonvico. (2016) Application of RPMI 2650 nasal cell model to a 3D printed apparatus for the testing of drug deposition and permeation of nasal products. European Journal of Pharmaceutics and Biopharmaceutics 107, pages 223-233.
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