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Expert Opinion on Drug Metabolism & Toxicology Volume 2, 2006 - Issue 1
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Review

Mitochondria: new drug targets for oxidative stress-induced diseases

M W Anders Professor Emeritus, Department of Pharmacology & Physiology, Anesthesiology and Environmental MedicineUniversity of Rochester Medical Center, Departments of Pharmacology and Physiology, of Anesthesiology, and of Environmental Medicine, 601 Elmwood Avenue, Rochester, New York 14642, USA. [email protected]
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James L Robotham Professor, Department of Anesthesiology, Pediatrics and Pharmacology & Physiology, University of Rochester Medical Center, Departments of Anesthesiology, of Pediatrics, and of Pharmacology and Physiology, 601 Elmwood Avenue, Rochester, New York 14642, USA. [email protected]
&
Shey-Shing Sheu Professor of Pharmacology & Physiology and Anesthesiology, University of Rochester Medical Center, Departments of Pharmacology and Physiology, of Anesthesiology, and of Medicine, 601 Elmwood Avenue, Rochester, New York 14642, USA
Pages 71-79 | Published online: 01 Feb 2006

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Shuang Zhou, Yanhui Sun, Xiao Kuang, Shanshan Hou, Zhenjie Wang, Zhe Qian & Hongzhuo Liu. (2018) Mitochondria-homing peptide functionalized nanoparticles performing dual extracellular/intracellular roles to inhibit aminoglycosides induced ototoxicity. Artificial Cells, Nanomedicine, and Biotechnology 46:sup2, pages 314-323.
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ChristopherM. Hattan, Jalil Shojaie, SerrineS. Lau & M.W. Anders. (2013) Synthesis of 3-(1-Methyl-1H-imidazol-2-ylthio)propanoic Acid and (E)-3-(1-Methyl-1H-imidazol-2-ylthio)acrylic Acid. Synthetic Communications 43:1, pages 1-8.
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Articles from other publishers (15)

Luís S. Monteiro & Fátima Paiva-Martins. 2022. Lipid Oxidation in Food and Biological Systems. Lipid Oxidation in Food and Biological Systems 381 404 .
Daniel T. Hass & Colin J. Barnstable. (2021) Uncoupling proteins in the mitochondrial defense against oxidative stress. Progress in Retinal and Eye Research 83, pages 100941.
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Carlos Fernandes, Sofia Benfeito, Ricardo Amorim, José Teixeira, Paulo J. Oliveira, Fernando Remião & Fernanda Borges. (2018) Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy. Bioconjugate Chemistry 29:8, pages 2723-2733.
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Paraskevi Pavlakou, Vassilios Liakopoulos, Theodoros Eleftheriadis, Michael Mitsis & Evangelia Dounousi. (2017) Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives. Oxidative Medicine and Cellular Longevity 2017, pages 1-11.
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Joanna Fiedor & Květoslava Burda. (2014) Potential Role of Carotenoids as Antioxidants in Human Health and Disease. Nutrients 6:2, pages 466-488.
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Theodore Kalogeris, Yimin Bao & Ronald J. Korthuis. (2014) Mitochondrial reactive oxygen species: A double edged sword in ischemia/reperfusion vs preconditioning. Redox Biology 2, pages 702-714.
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Aleksandra M. Urbanska, Valerio Zolla, Paolo Verzani & Laura Santambrogio. 2014. Immunology of Aging. Immunology of Aging 309 321 .
M.W. Anders. (2013) Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion 13:5, pages 454-463.
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Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu ChenJeak Ling Ding. (2012) Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence. Biochemical Journal 442:2, pages 263-271.
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Kavita K. Kumari & O. H. Setty. (2012) Protective effect of Phyllanthus fraternus against mitochondrial dysfunction induced by co-administration of cisplatin and cyclophosphamide. Journal of Bioenergetics and Biomembranes 44:1, pages 179-188.
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Jeffrey R. Erickson, B. Julie He, Isabella M. Grumbach & Mark E. Anderson. (2011) CaMKII in the Cardiovascular System: Sensing Redox States. Physiological Reviews 91:3, pages 889-915.
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M.W. Anders. (2011) Putting bioactivation reactions to work: Targeting antioxidants to mitochondria. Chemico-Biological Interactions 192:1-2, pages 8-13.
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Rame Taha, Ernest Seidman, Genevieve Mailhot, Fran?ois Boudreau, Fernand-Pierre Gendron, Jean-Fran?ois Beaulieu, Daniel M?nard, Edgard Delvin, Devendra Amre & Emile Levy. (2010) Oxidative Stress and Mitochondrial Functions in the Intestinal Caco-2/15 Cell Line. PLoS ONE 5:7, pages e11817.
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Kurt S. Roser, Paul S. Brookes, Andrew P. Wojtovich, Leif P. Olson, Jalil Shojaie, Richard L. Parton & M.W. Anders. (2010) Mitochondrial biotransformation of ω-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and ω-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: A prodrug strategy for targeting cytoprotective antioxidants to mitochondria. Bioorganic & Medicinal Chemistry 18:4, pages 1441-1448.
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Liang Shen, Hong-Fang Ji & Hong-Yu Zhang. (2007) How to understand the dichotomy of antioxidants. Biochemical and Biophysical Research Communications 362:3, pages 543-545.
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