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Genomic-based biomarkers of drug-induced nephrotoxicity

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Pages 95-101 | Published online: 01 Feb 2006

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Sung Ha Ryu, Ji Won Kim, Dahye Yoon, Suhkmann Kim & Kyu-Bong Kim. (2018) Serum and urine toxicometabolomics following gentamicin-induced nephrotoxicity in male Sprague-Dawley rats. Journal of Toxicology and Environmental Health, Part A 81:11, pages 408-420.
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Jasmine George, Richa Singh, Zafar Mahmood & Yogeshwer Shukla. (2010) Toxicoproteomics: New paradigms in toxicology research. Toxicology Mechanisms and Methods 20:7, pages 415-423.
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Articles from other publishers (22)

Jasmin Dilz, Isabel Auge, Kathrin Groeneveld, Stefanie Reuter & Ralf Mrowka. (2023) A proof-of-concept assay for quantitative and optical assessment of drug-induced toxicity in renal organoids. Scientific Reports 13:1.
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Sung Ha Ryu, Jung Dae Lee, Ji Won Kim, Siwon Kim, Suhkmann Kim & Kyu-Bong Kim. (2019) <sup>1</sup>H NMR toxicometabolomics following cisplatin-induced nephrotoxicity in male rats. The Journal of Toxicological Sciences 44:1, pages 57-71.
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T. Rehman, Y.A. Goo, M.A. Shad & D.R. Goodlett. 2018. Comprehensive Toxicology. Comprehensive Toxicology 375 390 .
Linda Awdishu & Ravindra L. Mehta. (2017) The 6R’s of drug induced nephrotoxicity. BMC Nephrology 18:1.
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Yu Ri An, Jae Young Kim & Yang Seok Kim. (2016) Construction of a predictive model for evaluating multiple organ toxicity. Molecular & Cellular Toxicology 12:1, pages 1-6.
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Délia C. M. Santos, Marta L. Lima, Juliano S. Toledo, Paula A. Fernandes, Marta M. G. Aguiar, Ángeles López-Gonzálvez, Lucas A. M. Ferreira, Ana Paula Fernandes & Coral Barbas. (2016) Metabolomics as a tool to evaluate the toxicity of formulations containing amphotericin B, an antileishmanial drug. Toxicology Research 5:6, pages 1720-1732.
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A Jin Won, Siwon Kim, Yoon Gyoon Kim, Kyu-Bong Kim, Wahn Soo Choi, Sam Kacew, Kyeong Seok Kim, Jee H. Jung, Byung Mu Lee, Suhkmann Kim & Hyung Sik Kim. (2016) Discovery of urinary metabolomic biomarkers for early detection of acute kidney injury. Molecular BioSystems 12:1, pages 133-144.
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Anna I. Astashkina, Clint F. Jones, Giridhar Thiagarajan, Kristen Kurtzeborn, Hamid Ghandehari, Benjamin D. Brooks & David W. Grainger. (2014) Nanoparticle toxicity assessment using an in vitro 3-D kidney organoid culture model. Biomaterials 35:24, pages 6323-6331.
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Omari Bandele, Luísa Camacho, Martine Ferguson, Renate Reimschuessel, Cynthia Stine, Thomas Black, Nicholas Olejnik, Zachary Keltner, Michael Scott, Gonçalo Gamboa da Costa & Robert Sprando. (2013) Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure. Food and Chemical Toxicology 51, pages 106-113.
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Jinchun Sun, Sudeepa Bhattacharyya, Laura K. Schnackenberg, Lisa Pence, Yosuke Ando, Jun Zhang, Sharon Stewart, Barry Rosenzweig, Rodney Rouse, Didier Portilla & Richard D. Beger. (2012) Discovery of early urinary biomarkers in preclinical study of gentamicin-induced kidney injury and recovery in rats. Metabolomics 8:6, pages 1181-1193.
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Anna I. Astashkina, Brenda K. Mann, Glenn D. Prestwich & David W. Grainger. (2012) Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines. Biomaterials 33:18, pages 4712-4721.
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Lu?sa Camacho, Kevin P. Kelly, Frederick A. Beland & Gon?alo Gamboa da Costa. (2011) Gene expression of biomarkers of nephrotoxicity in F344 rats co-exposed to melamine and cyanuric acid for seven days. Toxicology Letters 206:2, pages 166-171.
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Shruta S. Dadarkar, Lyle C. Fonseca, Prabha B. Mishra, Aurelio S. Lobo, Lalit S. Doshi, Nilesh M. Dagia, Ashok K. Rangasamy & Muralidhara Padigaru. (2011) Phenotypic and genotypic assessment of concomitant drug‐induced toxic effects in liver, kidney and blood. Journal of Applied Toxicology 31:2, pages 117-130.
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He Wen, Hye-Ji Yang, Myung-Joo Choi, Hyuk-Nam Kwon, Min-Ah Kim, Soon-Sun Hong & Sung-Hyouk Park. (2011) Identification of Urinary Biomarkers Related to Cisplatin-Induced Acute Renal Toxicity Using NMR-Based Metabolomics. Biomolecules and Therapeutics 19:1, pages 38-44.
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F. Peter Guengerich. (2011) Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development. Drug Metabolism and Pharmacokinetics 26:1, pages 3-14.
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B. Alex Merrick & Maribel E. Bruno. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 33 .
Kurt J. Boudonck, Matthew W. Mitchell, László Német, Lilla Keresztes, Abraham Nyska, Doron Shinar & Moti Rosenstock. (2009) Discovery of Metabolomics Biomarkers for Early Detection of Nephrotoxicity. Toxicologic Pathology 37:3, pages 280-292.
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Hisaharu Yamada. (2009) Evaluation methods for nephrotoxicity. Folia Pharmacologica Japonica 133:3, pages 154-157.
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B. Alex Merrick & Frank A. Witzmann. 2009. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 367 400 .
Dimitri Semizarov & Eric Blomme. 2008. Genomics in Drug Discovery and Development. Genomics in Drug Discovery and Development 219 291 .
Er-Jia Wang, Ronald D. Snyder, Mark R. Fielden, Roger J. Smith & Yi-Zhong Gu. (2008) Validation of putative genomic biomarkers of nephrotoxicity in rats. Toxicology 246:2-3, pages 91-100.
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Parvaneh Espandiari, Jun Zhang, Barry A. Rosenzweig, Vishal S. Vaidya, Jinchun Sun, Laura Schnackenberg, Eugene H. Herman, Alan Knapton, Joseph V. Bonventre, Richard D. Beger, Karol L. Thompson & Joseph Hanig. (2007) The Utility of a Rodent Model in Detecting Pediatric Drug-Induced Nephrotoxicity. Toxicological Sciences 99:2, pages 637-648.
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