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Han Li, Yu-Guang Wang, Zeng-Chun Ma, Gao Yun-Hang, Song Ling, Chen Teng-Fei, Zhang Guang-Ping & Yue Gao. (2021) A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction. Xenobiotica 51:7, pages 752-763.
Read now
Read now
Risto O. Juvonen, Mira Ahinko, Juhani Huuskonen, Hannu Raunio & Olli T. Pentikäinen. (2019) Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes. Xenobiotica 49:9, pages 1015-1024.
Read now
Read now
Bassem Sadek, Ali Saad, Gniewomir Latacz, Kamil Kuder, Agnieszka Olejarz, Tadeusz Karcz, Holger Stark & Katarzyna Kieć-Kononowicz. (2016) Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats. Drug Design, Development and Therapy 10, pages 3879-3898.
Read now
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Sabine Plöttner, Lilian Annika Bastian, Heiko Udo Käfferlein & Thomas Brüning. (2016) Effects of benzo[a]pyrene, aromatic amines, and a combination of both on CYP1A1 activities in RT-4 human bladder papilloma cells. Journal of Toxicology and Environmental Health, Part A 79:22-23, pages 1106-1117.
Read now
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Chin Eng Ong, Yan Pan, Joon Wah Mak & Rusli Ismail. (2013)
In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability. Expert Opinion on Drug Metabolism & Toxicology 9:9, pages 1097-1113.
Read now
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James J Cali, Dongping Ma, Monika G Wood, Poncho L Meisenheimer & Dieter H Klaubert. (2012) Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates. Expert Opinion on Drug Metabolism & Toxicology 8:9, pages 1115-1130.
Read now
Read now
James J Cali, Andrew Niles, Michael P Valley, Martha A O'Brien, Terry L Riss & John Shultz. (2008) Bioluminescent assays for ADMET. Expert Opinion on Drug Metabolism & Toxicology 4:1, pages 103-120.
Read now
Read now
Jan L Wahlstrom, Dan A Rock, J Greg Slatter & Larry C Wienkers. (2006) Advances in predicting CYP-mediated drug interactions in the drug discovery setting. Expert Opinion on Drug Discovery 1:7, pages 677-691.
Read now
Read now
Articles from other publishers (140)
Ziru Dai, Yue Wu, Yuan Xiong, Jingjing Wu, Min Wang, Xiao Sun, Xinxin Ding, Ling Yang, Xiaobo Sun & Guangbo Ge. (2023) CYP1A inhibitors: Recent progress, current challenges, and future perspectives. Medicinal Research Reviews 44:1, pages 169-234.
Crossref
Crossref
Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang & Guangbo Ge. (2023) Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions. Drug Metabolism and Disposition 51:10, pages 1254-1272.
Crossref
Crossref
Adam Yasgar, Danielle Bougie, Richard T. Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K. Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V. Zakharov & Anton Simeonov. (2023) Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS Pharmacology & Translational Science 6:5, pages 683-701.
Crossref
Crossref
Artitaya Thiengsusuk, Tullayakorn Plengsuriyakarn & Kesara Na-Bangchang. (2023) Modulatory Effects of Atractylodin and β-Eudesmol on Human Cytochrome P450 Enzymes: Potential Drug-Drug Interactions. Molecules 28:7, pages 3140.
Crossref
Crossref
Elizabeth M.J. Gillam & Valerie M. Kramlinger. (2023) Opportunities for Accelerating Drug Discovery and Development by Using Engineered Drug-Metabolizing Enzymes. Drug Metabolism and Disposition 51:3, pages 392-402.
Crossref
Crossref
Jie Zhao, Xue Zhang, Yueyin Wang, Huimin Huang, Shishir Sharma, Sangeeta Shrestha Sharma, Clemens Alexander Wolf, Sijie Liu, Gerhard Wolber, Erik J. Sorensen & Matthias Bureik. (2022) Exploring the Chemical Space of Proluciferins as Probe Substrates for Human Cytochrome P450 Enzymes. Applied Biochemistry and Biotechnology 195:2, pages 1042-1058.
Crossref
Crossref
Kasem KulkeawKasem Kulkeaw. 2023. Emergence of In Vitro 3D Systems to Model Human Malaria. Emergence of In Vitro 3D Systems to Model Human Malaria
45
66
.
Muhammad Asyraf Abduraman, Nor Hidayah Mustafa, Nik Soriani Yaacob, Azimah Amanah & Mei Lan Tan. (2022) Cytochrome P450 inhibition activities of non-standardized botanical products. Journal of Ethnopharmacology 296, pages 115406.
Crossref
Crossref
Michał Abram, Marcin Jakubiec, Katelyn Reeb, Mary Hongying Cheng, Robin Gedschold, Anna Rapacz, Szczepan Mogilski, Katarzyna Socała, Dorota Nieoczym, Małgorzata Szafarz, Gniewomir Latacz, Bartłomiej Szulczyk, Justyna Kalinowska-Tłuścik, Kinga Gawel, Camila V. Esguerra, Elżbieta Wyska, Christa E. Müller, Ivet Bahar, Andréia C. K. Fontana, Piotr Wlaź, Rafał M. Kamiński & Krzysztof Kamiński. (2022)
Discovery of (
R
)-
N
-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [
(
R
)-AS-1
], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity
In Vivo
. Journal of Medicinal Chemistry 65:17, pages 11703-11725.
Crossref
Crossref
Ya-Jun Liu. (2022) Understanding the complete bioluminescence cycle from a multiscale computational perspective: A review. Journal of Photochemistry and Photobiology C: Photochemistry Reviews 52, pages 100537.
Crossref
Crossref
Menglu Li, Yasunori Nawa, Seiichi Ishida, Yasunari Kanda, Satoshi Fujita & Katsumasa Fujita. (2022) Label-free chemical imaging of cytochrome P450 activity by Raman microscopy. Communications Biology 5:1.
Crossref
Crossref
Hannah M. Work, Sylvie E. Kandel & Jed N. Lampe. (2021) Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening. Scientific Reports 11:1.
Crossref
Crossref
Satoshi Yawata, Kenichi Noda, Ai Shimomura & Akio Kuroda. (2021) Mutant firefly luciferase enzymes resistant to the inhibition by sodium chloride. Biotechnology Letters 43:8, pages 1585-1594.
Crossref
Crossref
Ann-Kathrin Loerracher & Thomas Braunbeck. (2021) Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review. Archives of Toxicology 95:7, pages 2299-2334.
Crossref
Crossref
Shishir Sharma, Sangeeta Shrestha Sharma, Xue Zhang, Jan‐Philipp Bureik, Erik J. Sorensen & Matthias Bureik. (2021) Conversion of five proluciferin esters by human cytochrome P450 enzymes. Biotechnology Journal 16:7.
Crossref
Crossref
Lei Feng, Jing Ning, Xiangge Tian, Chao Wang, Zhenlong Yu, Xiaokui Huo, Tian Xie, Baojing Zhang, Tony D. James & Xiaochi Ma. (2021) Fluorescent probes for the detection and imaging of Cytochrome P450. Coordination Chemistry Reviews 437, pages 213740.
Crossref
Crossref
Yi Hsiao, Bo-Han Su & Yufeng J Tseng. (2021) Current development of integrated web servers for preclinical safety and pharmacokinetics assessments in drug development. Briefings in Bioinformatics 22:3.
Crossref
Crossref
Michał Abram, Anna Rapacz, Gniewomir Latacz, Bartłomiej Szulczyk, Justyna Kalinowska-Tłuścik, Dagmara Otto-Ślusarczyk, Marta Struga, Rafał M. Kamiński & Krzysztof Kamiński. (2021) Asymmetric synthesis and in vivo/in vitro characterization of new hybrid anticonvulsants derived from (2,5-dioxopyrrolidin-1-yl)phenylacetamides. Bioorganic Chemistry 109, pages 104751.
Crossref
Crossref
Kengo Sasaki, Makoto Inoue, Masakazu Machida, Tomoyuki Kawasaki, Satoru Tsuruta, Hajime Uchida, Seisuke Sakamoto, Mureo Kasahara, Akihiro Umezawa & Hidenori Akutsu. (2021) Human Pluripotent Stem Cell-Derived Organoids as a Model of Intestinal Xenobiotic Metabolism. StemJournal 3:1, pages 1-10.
Crossref
Crossref
Jingjing Wu, Xiaoqing Guan, Ziru Dai, Rongjing He, Xinxin Ding, Ling Yang & Guangbo Ge. (2021) Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives. Coordination Chemistry Reviews 427, pages 213600.
Crossref
Crossref
Jingyao Liu, David Machalz, Gerhard Wolber, Erik J. Sorensen & Matthias Bureik. (2020) New Proluciferin Substrates for Human CYP4 Family Enzymes. Applied Biochemistry and Biotechnology 193:1, pages 218-237.
Crossref
Crossref
Jia Jia. 2021. Cytochrome P450. Cytochrome P450
91
105
.
Ce Shi, Michael P. Killoran, Mary P. Hall, Paul Otto, Monika G. Wood, Ethan Strauss, Lance P. Encell, Thomas Machleidt, Keith V. Wood & Thomas A. Kirkland. (2020) 5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems. PLOS ONE 15:12, pages e0243747.
Crossref
Crossref
Shishir Sharma, Jingyao Liu, Xue Zhang, Sangeeta Shrestha Sharma, Erik J. Sorensen & Matthias Bureik. (2020) New luciferin-based probe substrates for human CYP26A1. Biochemistry and Biophysics Reports 24, pages 100861.
Crossref
Crossref
Michał Abram, Marcin Jakubiec, Anna Rapacz, Szczepan Mogilski, Gniewomir Latacz, Rafał M. Kamiński & Krzysztof Kamiński. (2020) The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure—Synthesis and In Vivo/In Vitro Studies. International Journal of Molecular Sciences 21:22, pages 8780.
Crossref
Crossref
George D. Hartman, Scott D. Kuduk, Christine Espiritu & Angela M. Lam. (2020)
P
450s
u
nder
Re
striction (PURE) Screen Using HepaRG and Primary Human Hepatocytes for Discovery of Novel HBV Antivirals
. ACS Medicinal Chemistry Letters 11:10, pages 1919-1927.
Crossref
Crossref
Krzysztof Kamiński, Szczepan Mogilski, Michał Abram, Anna Rapacz, Gniewomir Latacz, Bartłomiej Szulczyk, Maria Walczak, Kamil Kuś, Karolina Matyjaszczyk & Rafał M. Kamiński. (2020) KA‐104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models. Epilepsia 61:10, pages 2119-2128.
Crossref
Crossref
Safaa Yehia Eid, Mohammad Ahmad Althubiti, Mohamed E. Abdallah, Michael Wink & Mahmoud Zaki El-Readi. (2020) The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. Phytomedicine 77, pages 153280.
Crossref
Crossref
Shishir Sharma, Pradeepraj Durairaj & Matthias Bureik. (2020) Rapid and convenient biotransformation procedure for human drug metabolizing enzymes using permeabilized fission yeast cells. Analytical Biochemistry 607, pages 113704.
Crossref
Crossref
Xi Yang, Ping Feng, Lin Ma, Ting Kang, Shilong Hu, Ao Hai, Bowen Ke, Jin Liu & Minyong Li. (2020) Biological applications of a turn-on bioluminescent probe for monitoring sulfite oxidase deficiency in vivo. European Journal of Medicinal Chemistry 200, pages 112476.
Crossref
Crossref
Michał Abram, Anna Rapacz, Szczepan Mogilski, Gniewomir Latacz, Annamaria Lubelska, Rafał M. Kamiński & Krzysztof Kamiński. (2020) Multitargeted Compounds Derived from (2,5-Dioxopyrrolidin-1-yl)(phenyl)-Acetamides as Candidates for Effective Anticonvulsant and Antinociceptive Agents. ACS Chemical Neuroscience 11:13, pages 1996-2008.
Crossref
Crossref
Sangeeta Shrestha Sharma, Shishir Sharma & Matthias Bureik. (2020) Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails. Journal of Pharmaceutical Analysis 10:3, pages 271-276.
Crossref
Crossref
Sabina Podlewska, Gniewomir Latacz, Dorota Łażewska, Katarzyna Kieć-Kononowicz & Jadwiga Handzlik. (2020) In silico and in vitro studies on interaction of novel non-imidazole histamine H3R antagonists with CYP3A4. Bioorganic & Medicinal Chemistry Letters 30:11, pages 127147.
Crossref
Crossref
Brenton R. Ware, Grace E. Brown, Valerie Y. Soldatow, Edward L. LeCluyse & Salman R. Khetani. (2019) Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Strain and Species Comparison Studies During Drug Development. Gene Expression 19:3, pages 199-214.
Crossref
Crossref
Sandra Ortega Ugalde, Dongping Ma, James J. Cali & Jan N.M. Commandeur. (2019) Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis. SLAS Discovery 24:7, pages 745-754.
Crossref
Crossref
Tristan de Rond, Jian Gao, Amin Zargar, Markus de Raad, Jack Cunha, Trent R. Northen & Jay D. Keasling. (2019) A High‐Throughput Mass Spectrometric Enzyme Activity Assay Enabling the Discovery of Cytochrome P450 Biocatalysts. Angewandte Chemie International Edition 58:30, pages 10114-10119.
Crossref
Crossref
Tristan de Rond, Jian Gao, Amin Zargar, Markus de Raad, Jack Cunha, Trent R. Northen & Jay D. Keasling. (2019) A High‐Throughput Mass Spectrometric Enzyme Activity Assay Enabling the Discovery of Cytochrome P450 Biocatalysts. Angewandte Chemie 131:30, pages 10220-10225.
Crossref
Crossref
Noriaki Ikemura, Satoshi Yamaori, Chinatsu Kobayashi, Shinobu Kamijo, Norie Murayama, Hiroshi Yamazaki & Shigeru Ohmori. (2019) Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine. Chemico-Biological Interactions 306, pages 1-9.
Crossref
Crossref
Mahmoud Zaki El-Readi, SafaaYehia Eid, Ahmed Ali Abdelghany, Hiba Saeed Al-Amoudi, Thomas Efferth & Michael Wink. (2019) Resveratrol mediated cancer cell apoptosis, and modulation of multidrug resistance proteins and metabolic enzymes. Phytomedicine 55, pages 269-281.
Crossref
Crossref
Tommaso Felicetti, Rolando Cannalire, Donatella Pietrella, Gniewomir Latacz, Annamaria Lubelska, Giuseppe Manfroni, Maria Letizia Barreca, Serena Massari, Oriana Tabarrini, Katarzyna Kieć-Kononowicz, Bryan D. Schindler, Glenn W. Kaatz, Violetta Cecchetti & Stefano Sabatini. (2018)
2-Phenylquinoline
S. aureus
NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction
. Journal of Medicinal Chemistry 61:17, pages 7827-7848.
Crossref
Crossref
Dae-Seop Shin, Hyewon Seo, Jung Yoon Yang, Jeongmin Joo, So Hee Im, Seong Soon Kim, Sang Kyum Kim & Myung Ae Bae. (2018) Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids. International Journal of Toxicology 37:5, pages 393-403.
Crossref
Crossref
Satoshi Yamaori, Noriyuki Araki, Mio Shionoiri, Kurumi Ikehata, Shinobu Kamijo, Shigeru Ohmori & Kazuhito Watanabe. (2018) A Specific Probe Substrate for Evaluation of CYP4A11 Activity in Human Tissue Microsomes and a Highly Selective CYP4A11 Inhibitor: Luciferin-4A and Epalrestat. Journal of Pharmacology and Experimental Therapeutics 366:3, pages 446-457.
Crossref
Crossref
Michał Załuski, Katarzyna Stanuch, Tadeusz Karcz, Sonja Hinz, Gniewomir Latacz, Ewa Szymańska, Jakub Schabikowski, Agata Doroż-Płonka, Jadwiga Handzlik, Anna Drabczyńska, Christa E. Müller & Katarzyna Kieć-Kononowicz. (2018) Tricyclic xanthine derivatives containing a basic substituent: adenosine receptor affinity and drug-related properties. MedChemComm 9:6, pages 951-962.
Crossref
Crossref
Anna Więckowska, Tomasz Wichur, Justyna Godyń, Adam Bucki, Monika Marcinkowska, Agata Siwek, Krzysztof Więckowski, Paula Zaręba, Damijan Knez, Monika Głuch-Lutwin, Grzegorz Kazek, Gniewomir Latacz, Kamil Mika, Marcin Kołaczkowski, Jan Korabecny, Ondrej Soukup, Marketa Benkova, Katarzyna Kieć-Kononowicz, Stanislav Gobec & Barbara Malawska. (2018) Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer’s Disease. ACS Chemical Neuroscience 9:5, pages 1195-1214.
Crossref
Crossref
Tamer Nasr, Samir Bondock, Hassan M. Rashed, Walid Fayad, Mahmoud Youns & Tamer M. Sakr. (2018) Novel hydrazide-hydrazone and amide substituted coumarin derivatives: Synthesis, cytotoxicity screening, microarray, radiolabeling and in vivo pharmacokinetic studies. European Journal of Medicinal Chemistry 151, pages 723-739.
Crossref
Crossref
Dorota Łażewska, Maria Kaleta, Stefanie Hagenow, Szczepan Mogilski, Gniewomir Latacz, Tadeusz Karcz, Annamaria Lubelska, Ewelina Honkisz, Jadwiga Handzlik, David Reiner, Grzegorz Satała, Barbara Filipek, Holger Stark & Katarzyna Kieć-Kononowicz. (2018) Novel naphthyloxy derivatives – Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation. Bioorganic & Medicinal Chemistry 26:9, pages 2573-2585.
Crossref
Crossref
Gniewomir Latacz, Annamaria Lubelska, Magdalena Jastrzębska-Więsek, Anna Partyka, Katarzyna Kucwaj-Brysz, Anna Wesołowska, Katarzyna Kieć-Kononowicz & Jadwiga Handzlik. (2018) MF-8, a novel promising arylpiperazine-hydantoin based 5-HT 7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation. Bioorganic & Medicinal Chemistry Letters 28:5, pages 878-883.
Crossref
Crossref
Magdalena Jastrzębska-Więsek, Agata Siwek, Anna Partyka, Marcin Kołaczkowski, Maria Walczak, Magdalena Smolik, Gniewomir Latacz, Katarzyna Kieć-Kononowicz & Anna Wesołowska. (2017) Study on the effect of EMD386088, a 5-HT6 receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats. Naunyn-Schmiedeberg's Archives of Pharmacology 391:1, pages 37-49.
Crossref
Crossref
Gniewomir Latacz, Annamaria Lubelska, Magdalena Jastrzębska-Więsek, Anna Partyka, Andrzej Sobiło, Agnieszka Olejarz, Katarzyna Kucwaj-Brysz, Grzegorz Satała, Andrzej J. Bojarski, Anna Wesołowska, Katarzyna Kieć-Kononowicz & Jadwiga Handzlik. (2017)
In the search for a lead structure among series of potent and selective hydantoin 5-HT
7
R agents: The drug-likeness in vitro study
. Chemical Biology & Drug Design 90:6, pages 1295-1306.
Crossref
Crossref
Cindy Yanfei Li, Soowan Lee, Sara Cade, Li-Jung Kuo, Irvin R. Schultz, Deepak K. Bhatt, Bhagwat Prasad, Theo K. Bammler & Julia Yue Cui. (2017) Novel Interactions between Gut Microbiome and Host Drug-Processing Genes Modify the Hepatic Metabolism of the Environmental Chemicals Polybrominated Diphenyl Ethers. Drug Metabolism and Disposition 45:11, pages 1197-1214.
Crossref
Crossref
Matthew J. Traylor, Jong-Min Baek, Katelyn E. Richards, Roberto Fusetto, W. Huang, Peter Josh, Zhenzhong Chen, Padma Bollapragada, Richard A.J. O'Hair, Philip Batterham & Elizabeth M.J. Gillam. (2017) Recombinant expression and characterization of Lucilia cuprina CYP6G3: Activity and binding properties toward multiple pesticides. Insect Biochemistry and Molecular Biology 90, pages 14-22.
Crossref
Crossref
Michał Abram, Mirosław Zagaja, Szczepan Mogilski, Marta Andres-Mach, Gniewomir Latacz, Sebastian Baś, Jarogniew J. Łuszczki, Katarzyna Kieć-Kononowicz & Krzysztof Kamiński. (2017) Multifunctional Hybrid Compounds Derived from 2-(2,5-Dioxopyrrolidin-1-yl)-3-methoxypropanamides with Anticonvulsant and Antinociceptive Properties. Journal of Medicinal Chemistry 60:20, pages 8565-8579.
Crossref
Crossref
Dorota Łażewska, Maria Kaleta, J. Stephan Schwed, Tadeusz Karcz, Szczepan Mogilski, Gniewomir Latacz, Agnieszka Olejarz, Agata Siwek, Monika Kubacka, Annamaria Lubelska, Ewelina Honkisz, Jadwiga Handzlik, Barbara Filipek, Holger Stark & Katarzyna Kieć-Kononowicz. (2017) Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands. Bioorganic & Medicinal Chemistry 25:20, pages 5341-5354.
Crossref
Crossref
Masashi Asakawa, Yosuke Fukutani, Aulaphan Savangsuksa, Keiich Noguchi, Hiroaki Matsunami & Masafumi Yohda. (2017) Modification of the response of olfactory receptors to acetophenone by CYP1a2. Scientific Reports 7:1.
Crossref
Crossref
Johannes Hochleitner, Muhammad Akram, Martina Ueberall, Rohan A. Davis, Birgit Waltenberger, Hermann Stuppner, Sonja Sturm, Florian Ueberall, Johanna M. Gostner & Daniela Schuster. (2017) A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature. Scientific Reports 7:1.
Crossref
Crossref
Simone A. M. Badal, Malyn M. Asuncion Valenzuela, Dain Zylstra, George Huang, Pallavi Vendantam, Sheena Francis, Ashley Quitugua, Louisa H. Amis, Willie Davis, Tzuen-Rong J. Tzeng, Helen Jacobs, David J. Gangemi, Greg Raner, Leah Rowland, Jonathan Wooten, Petreena Campbell, Eileen Brantley & Rupika Delgoda. (2017)
Glaucarubulone glucoside from
Castela macrophylla
suppresses MCF-7 breast cancer cell growth and attenuates benzo[
a
]pyrene-mediated CYP1A gene induction
. Journal of Applied Toxicology 37:7, pages 873-883.
Crossref
Crossref
Kamil J. Kuder, Dorota Łażewska, Maria Kaleta, Gniewomir Latacz, Tim Kottke, Agnieszka Olejarz, Tadeusz Karcz, Andrzej Fruziński, Katarzyna Szczepańska, Janina Karolak-Wojciechowska, Holger Stark & Katarzyna Kieć-Kononowicz. (2017) Synthesis and biological activity of novel tert -amylphenoxyalkyl (homo)piperidine derivatives as histamine H 3 R ligands. Bioorganic & Medicinal Chemistry 25:10, pages 2701-2712.
Crossref
Crossref
Flavio Di Pisa, Giacomo Landi, Lucia Dello Iacono, Cecilia Pozzi, Chiara Borsari, Stefania Ferrari, Matteo Santucci, Nuno Santarem, Anabela Cordeiro-da-Silva, Carolina Moraes, Laura Alcantara, Vanessa Fontana, Lucio Freitas-Junior, Sheraz Gul, Maria Kuzikov, Birte Behrens, Ina Pöhner, Rebecca Wade, Maria Costi & Stefano Mangani. (2017) Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity. Molecules 22:3, pages 426.
Crossref
Crossref
M?hmoud Youns & Wael Abdel Halim Hegazy. (2017) The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways. PLOS ONE 12:1, pages e0169335.
Crossref
Crossref
Zi-Ru Dai, Lei Feng, Qiang Jin, Hailing Cheng, Yan Li, Jing Ning, Yang Yu, Guang-Bo Ge, Jing-Nan Cui & Ling Yang. (2017) A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study. Chemical Science 8:4, pages 2795-2803.
Crossref
Crossref
Paul Quehl, Joel Hollender, Jan Schüürmann, Tatjana Brossette, Ruth Maas & Joachim Jose. (2016) Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli. Microbial Cell Factories 15:1.
Crossref
Crossref
Christian Kölln & Stephan Reichl. (2016) Cytochrome P450 Activity in Ex Vivo Cornea Models and a Human Cornea Construct. Journal of Pharmaceutical Sciences 105:7, pages 2204-2212.
Crossref
Crossref
Katarzyna Kucwaj-Brysz, Dawid Warszycki, Sabina Podlewska, Jagna Witek, Karolina Witek, Andrea González Izquierdo, Grzegorz Satała, María I. Loza, Annamaria Lubelska, Gniewomir Latacz, Andrzej J. Bojarski, Marián Castro, Katarzyna Kieć-Kononowicz & Jadwiga Handzlik. (2016) Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation. European Journal of Medicinal Chemistry 112, pages 258-269.
Crossref
Crossref
Yitong Liu & Michael F. Santillo. (2015) Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements. Drug Testing and Analysis 8:3-4, pages 307-310.
Crossref
Crossref
Tal Yoetz-Kopelman, Carmit Porat-Ophir, Yosi Shacham-Diamand & Amihay Freeman. (2016) Whole-cell amperometric biosensor for screening of cytochrome P450 inhibitors. Sensors and Actuators B: Chemical 223, pages 392-399.
Crossref
Crossref
Masayuki Tsujimoto, Tomoe Uchida, Hiroyuki Kozakai, Saori Yamamoto, Tetsuya Minegaki & Kohshi Nishiguchi. (2016) Inhibitory Effects of Vegetable Juices on CYP3A4 Activity in Recombinant CYP3A4 and LS180 Cells. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:9, pages 1482-1487.
Crossref
Crossref
Kamil Kuder, Dorota Łażewska, Gniewomir Latacz, Johannes Stephan Schwed, Tadeusz Karcz, Holger Stark, Janina Karolak-Wojciechowska & Katarzyna Kieć-Kononowicz. (2016) Chlorophenoxy aminoalkyl derivatives as histamine H3R ligands and antiseizure agents. Bioorganic & Medicinal Chemistry 24:2, pages 53-72.
Crossref
Crossref
Katarzyna Kamińska, Julia Ziemba, Joanna Ner, Johannes Stephan Schwed, Dorota Łażewska, Małgorzata Więcek, Tadeusz Karcz, Agnieszka Olejarz, Gniewomir Latacz, Kamil Kuder, Tim Kottke, Małgorzata Zygmunt, Jacek Sapa, Janina Karolak-Wojciechowska, Holger Stark & Katarzyna Kieć-Kononowicz. (2015) (2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands. European Journal of Medicinal Chemistry 103, pages 238-251.
Crossref
Crossref
Ma?gorzata Zygmunt, Jacek Sapa, Anna Drabczy?ska, Tadeusz Karcz, Christa M?ller, Meryem K?se, Gniewomir Latacz, Jakub Schabikowski, Marek Bednarski & Katarzyna Kie?-Kononowicz. (2015) Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents. Archiv der Pharmazie 348:10, pages 704-714.
Crossref
Crossref
Young-Hoon Kim, Young-Ji Bae, Hyung Soo Kim, Hey-Jin Cha, Jae-Suk Yun, Ji-Soon Shin, Won-Keun Seong, Yong-Moon Lee & Kyoung-Moon Han. (2015) Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay. Biomolecules & Therapeutics 23:5, pages 486-492.
Crossref
Crossref
Krzysztof Kamiński, Mirosław Zagaja, Jarogniew J. Łuszczki, Anna Rapacz, Marta Andres-Mach, Gniewomir Latacz & Katarzyna Kieć-Kononowicz. (2015) Design, Synthesis, and Anticonvulsant Activity of New Hybrid Compounds Derived from 2-(2,5-Dioxopyrrolidin-1-yl)propanamides and 2-(2,5-Dioxopyrrolidin-1-yl)butanamides. Journal of Medicinal Chemistry 58:13, pages 5274-5286.
Crossref
Crossref
Michael S. Packer & David R. Liu. (2015) Methods for the directed evolution of proteins. Nature Reviews Genetics 16:7, pages 379-394.
Crossref
Crossref
Krzysztof Kami?ski, Anna Rapacz, Jarogniew J. ?uszczki, Gniewomir Latacz, Jolanta Obniska, Katarzyna Kie?-Kononowicz & Barbara Filipek. (2015) Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives. Bioorganic & Medicinal Chemistry 23:10, pages 2548-2561.
Crossref
Crossref
James B.Y.H. Behrendorff, Weiliang Huang & Elizabeth M.J. Gillam. (2015) Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity. Biochemical Journal 467:1, pages 1-15.
Crossref
Crossref
Hideo Takakura, Ryosuke Kojima, Mako Kamiya, Eiji Kobayashi, Toru Komatsu, Tasuku Ueno, Takuya Terai, Kenjiro Hanaoka, Tetsuo Nagano & Yasuteru Urano. (2015) New Class of Bioluminogenic Probe Based on Bioluminescent Enzyme-Induced Electron Transfer: BioLeT. Journal of the American Chemical Society 137:12, pages 4010-4013.
Crossref
Crossref
Safaa Yehia Eid, Mahmoud Zaki El-Readi, Mohamed Lotfy Ashour & Michael Wink. (2015)
Fallopia japonica
, a Natural Modulator, Can Overcome Multidrug Resistance in Cancer Cells
. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-8.
Crossref
Crossref
Robim M. Rodrigues, Joery De Kock, Tatyana Y. Doktorova, Vera Rogiers & Tamara Vanhaecke. 2015. Protocols in In Vitro Hepatocyte Research. Protocols in In Vitro Hepatocyte Research
279
285
.
Takafumi Katsumura, Shoji Oda, Shigeki Nakagome, Tsunehiko Hanihara, Hiroshi Kataoka, Hiroshi Mitani, Shoji Kawamura & Hiroki Oota. (2014)
Natural allelic variations of xenobiotic-metabolizing enzymes affect sexual dimorphism in
Oryzias latipes
. Proceedings of the Royal Society B: Biological Sciences 281:1797, pages 20142259.
Crossref
Crossref
Aurélien Godinat, Ghyslain Budin, Alma R. Morales, Hyo Min Park, Laura E. Sanman, Matthew Bogyo, Allen Yu, Andreas Stahl & Elena A. Dubikovskaya. (2014) A Biocompatible “Split Luciferin” Reaction and Its Application for Non‐Invasive Bioluminescent Imaging of Protease Activity in Living Animals. Current Protocols in Chemical Biology 6:3, pages 169-189.
Crossref
Crossref
Dorota Łażewska, Małgorzata Więcek, Joanna Ner, Katarzyna Kamińska, Tim Kottke, J. Stephan Schwed, Małgorzata Zygmunt, Tadeusz Karcz, Agnieszka Olejarz, Kamil Kuder, Gniewomir Latacz, Marek Grosicki, Jacek Sapa, Janina Karolak-Wojciechowska, Holger Stark & Katarzyna Kieć-Kononowicz. (2014) Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands. European Journal of Medicinal Chemistry 83, pages 534-546.
Crossref
Crossref
Michael G. Acker & Douglas S. Auld. (2014) Considerations for the design and reporting of enzyme assays in high-throughput screening applications. Perspectives in Science 1:1-6, pages 56-73.
Crossref
Crossref
Frederic D.L. Leusch, Stuart J. Khan, Somprasong Laingam, Erik Prochazka, Suzanne Froscio, Trang Trinh, Heather F. Chapman & Andrew Humpage. (2014) Assessment of the application of bioanalytical tools as surrogate measure of chemical contaminants in recycled water. Water Research 49, pages 300-315.
Crossref
Crossref
Seunghye Choi, Songhee Han, Hwayoun Lee, Young-Jin Chun & Donghak Kim. (2013) Evaluation of Luminescent P450 Analysis for Directed Evolution of Human CYP4A11. Biomolecules and Therapeutics 21:6, pages 487-492.
Crossref
Crossref
Aurélien Godinat, Hyo Min Park, Stephen C. Miller, Ke Cheng, Douglas Hanahan, Laura E. Sanman, Matthew Bogyo, Allen Yu, Gennady F. Nikitin, Andreas Stahl & Elena A. Dubikovskaya. (2013)
A Biocompatible
in Vivo
Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice
. ACS Chemical Biology 8:5, pages 987-999.
Crossref
Crossref
Matthew J. Cheesman, Matthew J. Traylor, Margaret E. Hilton, Katelyn E. Richards, Matthew C. Taylor, Phillip J. Daborn, Robyn J. Russell, Elizabeth M.J. Gillam & John G. Oakeshott. (2013) Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: Purification, activity, and binding properties toward multiple pesticides. Insect Biochemistry and Molecular Biology 43:5, pages 455-465.
Crossref
Crossref
David M. Stresser & George Zhang. 2013. High‐Throughput Screening Methods in Toxicity Testing. High‐Throughput Screening Methods in Toxicity Testing
453
477
.
Chunja Lee, Xinxin Ding & David S. Riddick. (2013) The Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-Methylcholanthrene. Drug Metabolism and Disposition 41:2, pages 457-465.
Crossref
Crossref
Mahmoud Zaki El-Readi, SafaaYehia Eid, Mohamed Lotfy Ashour, Ahmad Tahrani & Michael Wink. (2013) Modulation of multidrug resistance in cancer cells by chelidonine and Chelidonium majus alkaloids. Phytomedicine 20:3-4, pages 282-294.
Crossref
Crossref
Elwira Sieniawska, Tomasz Baj, Jarosław Dudka, Renata Gieroba, Lukasz Swiatek, Barbara Rajtar, Kazimierz Glowniak & Małgorzata Polz-Dacewicz. (2013) Cytotoxicity, antioxidant activity and an effect on CYP3A4 and CYP2D6 of Mutellina purpurea L. extracts. Food and Chemical Toxicology 52, pages 188-192.
Crossref
Crossref
Ido Goldstein, Noa Rivlin, Or-yam Shoshana, Osnat Ezra, Shalom Madar, Naomi Goldfinger & Varda Rotter. (2013) Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. Carcinogenesis 34:1, pages 190-198.
Crossref
Crossref
Angela Dudda & Gert Ulrich Kuerzel. 2013. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
989
1004
.
Douglas S. Auld, Henrike Veith & James J. Cali. 2013. Cytochrome P450 Protocols. Cytochrome P450 Protocols
1
9
.
Hongmao Sun, Henrike Veith, Menghang Xia, Christopher P. Austin, Raymond R. Tice & Ruili Huang. (2012) Prediction of Cytochrome P450 Profiles of Environmental Chemicals with QSAR Models Built from Drug‐Like Molecules. Molecular Informatics 31:11-12, pages 783-792.
Crossref
Crossref
Alexander V. LyubimovPeter L. Bullock & Olga V. Trubetskoy. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
26
.
Li Di & Edward H. Kerns. 2012. Chemical Biology. Chemical Biology
101
114
.
Mika Ito, Aya Shibata, Jie Zhang, Michio Hiroshima, Yasushi Sako, Yukiko Nakano, Kyoko Kojima‐Aikawa, Bengt Mannervik, Satoshi Shuto, Yoshihiro Ito, Ralf Morgenstern & Hiroshi Abe. (2012)
Universal Caging Group for the in‐Cell Detection of Glutathione Transferase Applied to
19
F NMR and Bioluminogenic Probes
. ChemBioChem 13:10, pages 1428-1432.
Crossref
Crossref
Andreas Benesic, Nora L Rahm, Samuel Ernst & Alexander L Gerbes. (2012) Human monocyte-derived cells with individual hepatocyte characteristics: a novel tool for personalized in vitro studies. Laboratory Investigation 92:6, pages 926-936.
Crossref
Crossref
Chiara Roncoroni, Nicoletta Rizzi, Electra Brunialti, James J. Cali, Dieter H. Klaubert, Adriana Maggi & Paolo Ciana. (2012) Molecular imaging of cytochrome P450 activity in mice. Pharmacological Research 65:5, pages 531-536.
Crossref
Crossref
Masashi Sekimoto, Shinsuke Sano, Takuomi Hosaka, Kiyomitsu Nemoto & Masakuni Degawa. (2012) Establishment of a Stable Human Cell Line, HPL-A3, for Use in Reporter Gene Assays of Cytochrome P450 3A Inducers. Biological and Pharmaceutical Bulletin 35:5, pages 677-685.
Crossref
Crossref
Susan L. Rowland, Gwen A. Lawrie, James B. Y. H. Behrendorff & Elizabeth M. J. Gillam. (2012) Is the undergraduate research experience (URE) always best?: The power of choice in a bifurcated practical stream for a large introductory biochemistry class. Biochemistry and Molecular Biology Education 40:1, pages 46-62.
Crossref
Crossref
Chunqi Li, Liqing Luo, Jessica Awerman & Patricia McGrath. 2011. Zebrafish. Zebrafish
103
115
.
Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert & James J. Cali. (2011) Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition. Drug Metabolism and Disposition 39:12, pages 2403-2410.
Crossref
Crossref
Ning Li, Qiong Hu, Canhua Jiang, Yanjia Hu, Yongxiang Yuan, Xinchun Jian, Zhangui Tang & Feng Guo. (2011) Novel genetic biomarkers for susceptibility to oral submucous fibrosis: Cytochrome P450 3A. Medical Hypotheses 77:5, pages 834-836.
Crossref
Crossref
Hongmao Sun, Henrike Veith, Menghang Xia, Christopher P. Austin & Ruili Huang. (2011) Predictive Models for Cytochrome P450 Isozymes Based on Quantitative High Throughput Screening Data. Journal of Chemical Information and Modeling 51:10, pages 2474-2481.
Crossref
Crossref
Maryam Modarai, Andy Suter, Andreas Kortenkamp & Michael Heinrich. (2011)
The interaction potential of herbal medicinal products: a luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (
Harpagophyti radix
) preparations
. Journal of Pharmacy and Pharmacology 63:3, pages 429-438.
Crossref
Crossref
Brad Larson, Peter Banks, James J. Cali, Mary Sobol & Sarah Shultz. (2011) Automated Luminescence-Based Cytochrome P450 Profiling Using a Simple, Elegant Robotic Platform. JALA: Journal of the Association for Laboratory Automation 16:1, pages 47-55.
Crossref
Crossref
Yoshiyuki Yamaura, Kouichi Yoshinari & Yasushi Yamazoe. (2011) Predicting Oxidation Sites with Order of Occurrence among Multiple Sites for CYP4A-mediated Reactions. Drug Metabolism and Pharmacokinetics 26:4, pages 351-363.
Crossref
Crossref
Hisakazu Sanada, Masashi Sekimoto, Ayaka Kamoshita & Masakuni Degawa. (2011) Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats. The Journal of Toxicological Sciences 36:2, pages 181-190.
Crossref
Crossref
Yuko Takeba, Naoki Matsumoto, Sachiko Takenoshita-Nakaya, Yoshie Harimoto, Toshio Kumai, Yuichi Kinoshita, Hiroshi Nakano, Takehito Ohtsubo & Shinichi Kobayashi. (2011) Comparative Study of Culture Conditions for Maintaining CYP3A4 and ATP-Binding Cassette Transporters Activity in Primary Cultured Human Hepatocytes. Journal of Pharmacological Sciences 115:4, pages 516-524.
Crossref
Crossref
J. Matthew Hutzler, Jack Cook & Joseph C. Fleishaker. 2011. Pharmacokinetics in Drug Development. Pharmacokinetics in Drug Development
21
56
.
Remigijus Didziapetris, Justas Dapkunas, Andrius Sazonovas & Pranas Japertas. (2010) Trainable structure–activity relationship model for virtual screening of CYP3A4 inhibition. Journal of Computer-Aided Molecular Design 24:11, pages 891-906.
Crossref
Crossref
Natasha Thorne, James Inglese & Douglas S. Auld. (2010) Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology. Chemistry & Biology 17:6, pages 646-657.
Crossref
Crossref
Donald J. AbrahamDaniele Carettoni & Philippe Verwaerde. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
401
436
.
Jens P. von Kries, Thulasi Warrier & Larissa M. Podust. (2010) Identification of Small‐Molecule Scaffolds for P450 Inhibitors. Current Protocols in Microbiology 16:1.
Crossref
Crossref
R. Scott Obach. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development
241
264
.
Christophe Morisseau, Oleg Merzlikin, Amy Lin, Guochun He, Wei Feng, Isela Padilla, Michael S. Denison, Isaac N. Pessah & Bruce D. Hammock. (2009) Toxicology in the Fast Lane: Application of High-Throughput Bioassays to Detect Modulation of Key Enzymes and Receptors. Environmental Health Perspectives 117:12, pages 1867-1872.
Crossref
Crossref
Henrike Veith, Noel Southall, Ruili Huang, Tim James, Darren Fayne, Natalia Artemenko, Min Shen, James Inglese, Christopher P Austin, David G Lloyd & Douglas S Auld. (2009) Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries. Nature Biotechnology 27:11, pages 1050-1055.
Crossref
Crossref
Qian Cheng, Christal D Sohl & F Peter Guengerich. (2009) High-throughput fluorescence assay of cytochrome P450 3A4. Nature Protocols 4:9, pages 1258-1261.
Crossref
Crossref
Kathryn E. Luker, Mudit Gupta & Gary D. Luker. (2009) Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. BioTechniques 47:1, pages 625-632.
Crossref
Crossref
Livia Capponi, Andrea Schmitz, Wolfgang Thormann, Regula Theurillat & Meike Mevissen. (2009) In vitro evaluation of differences in phase 1 metabolism of ketamine and other analgesics among humans, horses, and dogs. American Journal of Veterinary Research 70:6, pages 777-786.
Crossref
Crossref
Céline Narjoz, Laetitia Marisa, Sandrine Imbeaud, Alain Paris, Hervé Delacroix, Philippe Beaune & Isabelle De Waziers. (2009) Genomic Consequences of Cytochrome P450 2C9 Overexpression in Human Hepatoma Cells. Chemical Research in Toxicology 22:5, pages 779-787.
Crossref
Crossref
Ryan MacArthur, William Leister, Henrike Veith, Paul Shinn, Noel Southall, Christopher P. Austin, James Inglese & Douglas S. Auld. (2009) Monitoring Compound Integrity With Cytochrome P450 Assays and qHTS. SLAS Discovery 14:5, pages 538-546.
Crossref
Crossref
Ana M Gomes, Stefan Winter, Kathrin Klein, Miia Turpeinen, Elke Schaeffeler, Matthias Schwab & Ulrich M Zanger. (2009) Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation. Pharmacogenomics 10:4, pages 579-599.
Crossref
Crossref
Kalvin J. Gregory & Yeh Sun. (2009) Reduction of sample evaporation in small volume microplate luminescence assays. Analytical Biochemistry 387:2, pages 321-323.
Crossref
Crossref
Douglas S. Auld, Ya-Qin Zhang, Noel T. Southall, Ganesha Rai, Marc Landsman, Jennifer MacLure, Daniel Langevin, Craig J. Thomas, Christopher P. Austin & James Inglese. (2009) A Basis for Reduced Chemical Library Inhibition of Firefly Luciferase Obtained from Directed Evolution. Journal of Medicinal Chemistry 52:5, pages 1450-1458.
Crossref
Crossref
Daniel E. Conway, Yumiko Sakurai, Daiana Weiss, J. David Vega, W. Robert Taylor, Hanjoong Jo, Suzanne G. Eskin, Craig B. Marcus & Larry V. McIntire. (2009) Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress. Cardiovascular Research 81:4, pages 669-677.
Crossref
Crossref
A. B. Inceoglu, T. D. Waite, J. A. Christiansen, R. D. McAbee, S. G. Kamita, B. D. Hammock & A. J. Cornel. (2009)
A Rapid Luminescent Assay for Measuring Cytochrome P450 Activity in Individual Larval
Culex pipiens
Complex Mosquitoes (Diptera: Culicidae)
. Journal of Medical Entomology 46:1, pages 83-92.
Crossref
Crossref
Georges Degenfeld, Tom S. Wehrman & Helen M. Blau. 2009. Bioluminescence. Bioluminescence
249
259
.
Carolyn C. Woodroofe, John W. Shultz, Monika G. Wood, Jean Osterman, James J. Cali, William J. Daily, Poncho L. Meisenheimer & Dieter H. Klaubert. (2008) N-Alkylated 6′-Aminoluciferins Are Bioluminescent Substrates for Ultra-Glo and QuantiLum Luciferase: New Potential Scaffolds for Bioluminescent Assays. Biochemistry 47:39, pages 10383-10393.
Crossref
Crossref
Stephen Fowler & Hongjian Zhang. (2008) In Vitro Evaluation of Reversible and Irreversible Cytochrome P450 Inhibition: Current Status on Methodologies and their Utility for Predicting Drug–Drug Interactions. The AAPS Journal 10:2, pages 410-424.
Crossref
Crossref
Martha C. Garcia, Dongping Ma, A. Thomas DiCioccio & James Cali. (2008) The use of a high-throughput luminescent method to assess CYP3A enzyme induction in cultured rat hepatocytes. In Vitro Cellular & Developmental Biology - Animal 44:5-6, pages 129-134.
Crossref
Crossref
Jiunn-Jye Chuu, Zih-Ning Huang, Hsun-Hsin Yu, Liang-Hao Chang & Shoei-Yn Lin-Shiau. (2007) Attenuation by methyl mercury and mercuric sulfide of pentobarbital induced hypnotic tolerance in mice through inhibition of ATPase activities and nitric oxide production in cerebral cortex. Archives of Toxicology 82:6, pages 343-353.
Crossref
Crossref
Tadhg P. BegleyLi Di & Edward H. Kerns. 2007. Wiley Encyclopedia of Chemical Biology. Wiley Encyclopedia of Chemical Biology
1
8
.
Dan Rock, Jan Wahlstrom & Larry Wienkers. 2008. Antitargets. Antitargets
195
246
.
Walter M.A. Westerink & Willem G.E.J. Schoonen. (2007) Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicology in Vitro 21:8, pages 1581-1591.
Crossref
Crossref
Yoshiaki Yasutake, Noriko Imoto, Yoshikazu Fujii, Tadashi Fujii, Akira Arisawa & Tomohiro Tamura. (2007) Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105). Biochemical and Biophysical Research Communications 361:4, pages 876-882.
Crossref
Crossref
Tong Lin, Kristine Pan, Joyce Mordenti & Lin Pan. (2007) In vitro assessment of cytochrome P450 inhibition: Strategies for increasing LC/MS‐based assay throughput using a one‐point IC50 method and multiplexing high‐performance liquid chromatography. Journal of Pharmaceutical Sciences 96:9, pages 2485-2493.
Crossref
Crossref
Elizabeth M.J. Gillam. (2007) Extending the capabilities of nature’s most versatile catalysts: Directed evolution of mammalian xenobiotic-metabolizing P450s. Archives of Biochemistry and Biophysics 464:2, pages 176-186.
Crossref
Crossref
Alexandre Olry, Florence Schneider-Belhaddad, Dimitri Heintz & Danièle Werck-Reichhart. (2007) A medium-throughput screening assay to determine catalytic activities of oxygen-consuming enzymes: a new tool for functional characterization of cytochrome P450 and other oxygenases. The Plant Journal 51:2, pages 331-340.
Crossref
Crossref
Frank Fan & Keith V. Wood. (2007) Bioluminescent Assays for High-Throughput Screening. ASSAY and Drug Development Technologies 5:1, pages 127-136.
Crossref
Crossref