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Drug Evaluations

Laquinimod: a promising oral medication for the treatment of relapsing-remitting multiple sclerosis

, MD & , MD
Pages 365-370 | Published online: 10 Feb 2011

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Read on this site (6)

Jan Thöne & Ralf A Linker. (2016) Laquinimod in the treatment of multiple sclerosis: a review of the data so far. Drug Design, Development and Therapy 10, pages 1111-1118.
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Catalina Coclitu, Cris S. Constantinescu & Radu Tanasescu. (2016) The future of multiple sclerosis treatments. Expert Review of Neurotherapeutics 16:12, pages 1341-1356.
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Simona E Constantinescu & Cris S Constantinescu. (2016) Laquinimod (ABR-215062) for the treatment of relapsing multiple sclerosis. Expert Review of Clinical Pharmacology 9:1, pages 49-57.
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Jan Thöne & Gisa Ellrichmann. (2013) Oral available agents in the treatment of relapsing remitting multiple sclerosis: an overview of merits and culprits. Drug, Healthcare and Patient Safety 5, pages 37-47.
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Jan Thöne & Ralf Gold. (2013) Review of laquinimod and its therapeutic potential in multiple sclerosis. Expert Opinion on Pharmacotherapy 14:18, pages 2545-2552.
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Wolfgang Brück & Scott S Zamvil. (2012) Laquinimod, a once-daily oral drug in development for the treatment of relapsing–remitting multiple sclerosis. Expert Review of Clinical Pharmacology 5:3, pages 245-256.
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Articles from other publishers (14)

Hélèna L. Denis, Florian Lauruol & Francesca Cicchetti. (2018) Are immunotherapies for Huntington’s disease a realistic option?. Molecular Psychiatry 24:3, pages 364-377.
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Mehrdad Gholamzad, Masoumeh Ebtekar, Mehdi Shafiee Ardestani, Maryam Azimi, Zeinab Mahmodi, Mohammad Javad Mousavi & Saeed Aslani. (2018) A comprehensive review on the treatment approaches of multiple sclerosis: currently and in the future. Inflammation Research 68:1, pages 25-38.
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Gisa Ellrichmann, Alina Blusch, Oluwaseun Fatoba, Janine Brunner, Christiane Reick, Liat Hayardeny, Michael Hayden, Dominik Sehr, Konstanze F. Winklhofer, Carsten Saft & Ralf Gold. (2017) Laquinimod treatment in the R6/2 mouse model. Scientific Reports 7:1.
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Agnieszka Morel, Joanna Rywaniak, Michał Bijak, Elżbieta Miller, Marta Niwald & Joanna Saluk. (2017) Flow cytometric analysis reveals the high levels of platelet activation parameters in circulation of multiple sclerosis patients. Molecular and Cellular Biochemistry 430:1-2, pages 69-80.
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Irit Gil-Ad, Ben H. Amit, Liat Hayardeni, Igor Tarasenko, Michal Taler, Ravit Uzan Gueta & Abraham Weizman. (2014) Effects of the Anti-Multiple Sclerosis Immunomodulator Laquinimod on Anxiety and Depression in Rodent Behavioral Models. Journal of Molecular Neuroscience 55:2, pages 552-560.
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Bernd C. Kieseier. (2014) Defining a role for laquinimod in multiple sclerosis. Therapeutic Advances in Neurological Disorders 7:4, pages 195-205.
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Channa Kolb-Sobieraj, Sahil Gupta & Bianca Weinstock-Guttman. (2014) Laquinimod Therapy in Multiple Sclerosis: A Comprehensive Review. Neurology and Therapy 3:1, pages 29-39.
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T. L. Vollmer, P. S. Sorensen, K. Selmaj, F. Zipp, E. Havrdova, J. A. Cohen, N. Sasson, Y. Gilgun-Sherki & D. L. Arnold. (2014) A randomized placebo-controlled phase III trial of oral laquinimod for multiple sclerosis. Journal of Neurology 261:4, pages 773-783.
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Ioan Buraga & Roxana-Elena Popovici. (2014) Multiple Sclerosis and Pregnancy: Current Considerations. The Scientific World Journal 2014, pages 1-6.
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Bruce AC Cree. (2013) Update on reproductive safety of current and emerging disease-modifying therapies for multiple sclerosis. Multiple Sclerosis Journal 19:7, pages 835-843.
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Jack P. Antel & Veronique E. Miron. 2013. Myelin Repair and Neuroprotection in Multiple Sclerosis. Myelin Repair and Neuroprotection in Multiple Sclerosis 203 231 .
Elias Toubi, Shahar Nussbaum, Elsebeth Staun-Ram, Ayelet Snir, Doron Melamed, Liat Hayardeny & Ariel Miller. (2012) Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis. Journal of Neuroimmunology 251:1-2, pages 45-54.
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Wanda Castro-Borrero, Donna Graves, Teresa C. Frohman, Angela Bates Flores, Paula Hardeman, Diana Logan, Megan Orchard, Benjamin Greenberg & Elliot M. Frohman. (2012) Current and emerging therapies in multiple sclerosis: a systematic review. Therapeutic Advances in Neurological Disorders 5:4, pages 205-220.
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Jan Thöne, Gisa Ellrichmann, Silvia Seubert, Isabella Peruga, De-Hyung Lee, Rebecca Conrad, Liat Hayardeny, Giancarlo Comi, Stefan Wiese, Ralf A. Linker & Ralf Gold. (2012) Modulation of Autoimmune Demyelination by Laquinimod via Induction of Brain-Derived Neurotrophic Factor. The American Journal of Pathology 180:1, pages 267-274.
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