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Expert Opinion on Drug Metabolism & Toxicology Volume 7, 2011 - Issue 3
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Drug Evaluations

Pharmacokinetic evaluation of ambrisentan

Mitchell S Buckley Banner Good Samaritan Medical Center, Department of Pharmacy, 1111 E. McDowell Rd, Phoenix, AZ 85006, USA
, PharmD BCPS FCCM,
Laura M Wicks Banner Good Samaritan Medical Center, Department of Pharmacy, 1111 E. McDowell Rd, Phoenix, AZ 85006, USA
, PharmD,
Robin L Staib Banner Good Samaritan Medical Center, Department of Pharmacy, 1111 E. McDowell Rd, Phoenix, AZ 85006, USA
, PharmD,
Anna K Kirejczyk Banner Good Samaritan Medical Center, Department of Pharmacy, 1111 E. McDowell Rd, Phoenix, AZ 85006, USA
, PharmD,
Andrew S Varker Banner Good Samaritan Medical Center, Department of Pharmacy, 1111 E. McDowell Rd, Phoenix, AZ 85006, USA
, PharmD,
Jamie J Gibson St. Joseph's Hospital & Medical Center, Department of Pharmacy, 350 W. Thomas Rd, Phoenix, AZ 85013, USA
, PharmD &
Jeremy P Feldman Arizona Pulmonary Specialists, Ltd, 3330 N Second St. Suite 300, Phoenix, AZ 85012, USA +1 602 274 7195; +1 602 274 7097; [email protected]
, MD FCCP show all
Pages 371-380 | Published online: 08 Feb 2011

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Andrew J. Peacock, William Zamboni & Carmine Dario Vizza. (2015) Ambrisentan for the treatment of adults with pulmonary arterial hypertension: a review. Current Medical Research and Opinion 31:9, pages 1793-1807.
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Shunji Yoshida, Kunio Shirato, Ryutaro Shimamura, Takayuki Iwase, Narumi Aoyagi & Hiromu Nakajima. (2012) Long-term safety and efficacy of ambrisentan in Japanese adults with pulmonary arterial hypertension. Current Medical Research and Opinion 28:6, pages 1069-1076.
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Articles from other publishers (11)

Karen Paola Camarillo Cárdenas, Joceline Estefanía Rangel Velázquez, Javier Jesús Osorio Escobar, Juan Chirinos & Murali Pendela. (2020) Bioequivalence and Tolerability of Ambrisentan: A Pharmacokinetic Study in Mexican Healthy Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics 45:5, pages 611-618.
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Frederik C. Enevoldsen, Jayashree Sahana, Markus Wehland, Daniela Grimm, Manfred Infanger & Marcus Krüger. (2020) Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy. Journal of Clinical Medicine 9:3, pages 824.
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Lu Wang, Yali Wang, Lushan Yu, Cuirong Sun, Yu Kang & Su Zeng. (2018) Direct differentiation of stereoisomers of ezetimibe/ambrisentan/atorvastatin and their mechanism study by electrospray ionization quadrupole time-of-flight mass spectrometry. Journal of Mass Spectrometry 53:12, pages 1238-1246.
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Martin Bedan, Daniela Grimm, Markus Wehland, Ulf Simonsen, Manfred Infanger & Marcus Krüger. (2018) A Focus on Macitentan in the Treatment of Pulmonary Arterial Hypertension. Basic & Clinical Pharmacology & Toxicology 123:2, pages 103-113.
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Thies Schroeder, Claude A. Piantadosi, Michael J. Natoli, Julie Autmizguine, Michael Cohen‐Wolkowieczs, Karyn L. Hamilton, Christopher Bell, Jelena Klawitter, Uwe Christians, David C. Irwin & Robert J. Noveck. (2017) Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia. Clinical Pharmacology & Therapeutics 103:5, pages 888-898.
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Anhua Wei, Zhichun Gu, Juan Li, Xiaoyan Liu, Xiaofan Wu, Yi Han & Jun Pu. (2016) Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials. Journal of the American Heart Association 5:11.
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Xue-Qin Li, Yun-Jing Li & Yong Wang. (2015) Ambrisentan May Improve Exercise Tolerance and Cardiac Function in Patients With Pulmonary Hypertension. Clinical Therapeutics 37:6, pages 1270-1279.
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Meghan Aversa, Sandra Porter & John Granton. (2015) Comparative Safety and Tolerability of Endothelin Receptor Antagonists in Pulmonary Arterial Hypertension. Drug Safety 38:5, pages 419-435.
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M. P. Le, A. Gervais, C. Le Beller, K. Long, L. Larrouy, E. Papy, H. Mal, D. Descamps & G. Peytavin. (2013) Serious neuropsychiatric adverse effects in a hepatitis C virus/hepatitis B virus/HIV-coinfected patient receiving bosentan and telaprevir. Journal of Antimicrobial Chemotherapy 68:5, pages 1208-1209.
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Michele D’Alto. (2012) An update on the use of ambrisentan in pulmonary arterial hypertension. Therapeutic Advances in Respiratory Disease 6:6, pages 331-343.
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B. Preckel, S. Eberl, J. Fr??dorf & M.W. Hollmann. (2012) Management von Patienten mit pulmonaler HypertonieManagement of patients with pulmonary hypertension. Der Anaesthesist 61:7, pages 574-587.
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