Brandon S. Scott, Kelly Zhang, Peter M. Yehl & Samuel H. Yang. (2024) A strategic approach towards mass balance investigations in pharmaceutical drug substance release testing: A peculiar out of specification case study encountered during API manufacture. Journal of Pharmaceutical and Biomedical Analysis 238, pages 115773.
Crossref
Cátia D. Correia, Anita Ferreira, Mónica T. Fernandes, Bárbara M. Silva, Filipa Esteves, Helena S. Leitão, José Bragança & Sofia M. Calado. (2023) Human Stem Cells for Cardiac Disease Modeling and Preclinical and Clinical Applications—Are We on the Road to Success?. Cells 12:13, pages 1727.
Crossref
Cheng Fang, Ye Wang, Richard Grater, Sudarshan Kapadnis, Cheryl Black, Patrick Trapa & Simone Sciabola. (2023) Prospective Validation of Machine Learning Algorithms for Absorption, Distribution, Metabolism, and Excretion Prediction: An Industrial Perspective. Journal of Chemical Information and Modeling 63:11, pages 3263-3274.
Crossref
Sreeram Sudhir & Amritha Pozhaiparambil Sasikumar. 2023. Drug Formulation Design. Drug Formulation Design.
Elma Mons, Robbert Q. Kim & Monique P. C. Mulder. (2023) Technologies for Direct Detection of Covalent Protein–Drug Adducts. Pharmaceuticals 16:4, pages 547.
Crossref
Thirupathi Damera & Ramakanth Pagadala. (2023) A New and an Eco‐Friendly Approach for the Construction of Multi‐Functionalized Benzenes with Computational Studies. Chemistry & Biodiversity 20:4.
Crossref
Sarah Mousavi, Shima Zare, Mahmoud Mirzaei & Awat Feizi. (2022) Novel Drug Design for Treatment of COVID-19: A Systematic Review of Preclinical Studies. Canadian Journal of Infectious Diseases and Medical Microbiology 2022, pages 1-70.
Crossref
Hao Li, Yanling Guan, Bo Liang, Peng Ding, Xin Hou, Wei Wei & Yang Ma. (2022) Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome. European Journal of Pharmacology 928, pages 175091.
Crossref
Amritha Pozhaiparambil Sasikumar, SathishKumar Ramaswamy & Sreeram Sudhir. (2021) A scientific pharmacognosy on Gaucher’s disease: an in silico analysis. Environmental Science and Pollution Research 29:17, pages 25308-25317.
Crossref
Joseph E. Pero, John J. McAtee, David J. Behm, Jacques Briand, Grazyna Graczyk-Millbrandt, Karl Erhard, Andrew D. Roberts, Ralph A. Rivero, Dennis A. Holt & Brian G. Lawhorn. (2021) Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745. ACS Medicinal Chemistry Letters 12:9, pages 1498-1502.
Crossref
Gaspar Taroncher-Oldenburg, Christin Müller, Wiebke Obermann, John Ziebuhr, Roland K. Hartmann & Arnold Grünweller. (2021) Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates—A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics. Microorganisms 9:3, pages 540.
Crossref
Tingting Cai, Caisheng Wu, Qian Ruan, Shuguang Ma & Mingshe Zhu. 2020. Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters. Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters
73
117
.
D. Sujatha, Ch. Hepsiba Rani, Shaheen Begum, Sunitha Sampathi & Saurabh Shah. 2020. Advances in Computational and Bio-Engineering. Advances in Computational and Bio-Engineering
249
261
.
E. van de Steeg, F. H. J. Schuren, R. Scott Obach, C. van Woudenbergh, Gregory S. Walker, M. Heerikhuisen, I. H. G. Nooijen & W. H. J. Vaes. (2018) An Ex Vivo Fermentation Screening Platform to Study Drug Metabolism by Human Gut Microbiota. Drug Metabolism and Disposition 46:11, pages 1596-1607.
Crossref
Sneha ChintaShyam Kumar Vootla. (2018)
Pharmacokinetic Evaluation of Ofloxacin in an Invertebrate Animal Model Silkworm,
Bombyx mori
. Applied In Vitro Toxicology 4:1, pages 61-68.
Crossref
Paul A. Lapchak & John H. Zhang. (2016) The High Cost of Stroke and Stroke Cytoprotection Research. Translational Stroke Research 8:4, pages 307-317.
Crossref
Lisa Chedik, Dominique Mias-Lucquin, Arnaud Bruyere & Olivier Fardel. (2017) In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans. International Journal of Environmental Research and Public Health 14:7, pages 708.
Crossref
Michael D David. (2017) Insecticide ADME for support of early-phase discovery: combining classical and modern techniques. Pest Management Science 73:4, pages 692-699.
Crossref
Danielle Marquete Vitelli-Avelar, Renato Sathler-Avelar, Armanda Moreira Mattoso-Barbosa, Nicolas Gouin, Marcelo Perdigão-de-Oliveira, Leydiane Valério-dos-Reis, Ronaldo Peres Costa, Silvana Maria Elói-Santos, Matheus de Souza Gomes, Laurence Rodrigues do Amaral, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Edward J. Dick, Gene B. Hubbard, Jane F. VandeBerg & John L. VandeBerg. (2017) Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease. PLOS Neglected Tropical Diseases 11:2, pages e0005233.
Crossref
Paul A. Lapchak & Paul D. Boitano. 2017. Neuroprotective Therapy for Stroke and Ischemic Disease. Neuroprotective Therapy for Stroke and Ischemic Disease
3
71
.
Manohar Salla, Mark S. Butler, Ruby Pelingon, Geraldine Kaeslin, Daniel E. Croker, Janet C. Reid, Jong Min Baek, Paul V. Bernhardt, Elizabeth M. J. Gillam, Matthew A. Cooper & Avril A. B. Robertson. (2016) Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950. ACS Medicinal Chemistry Letters 7:12, pages 1034-1038.
Crossref
Philippa H. Harlow, Simon J. Perry, Stephanie Widdison, Shannon Daniels, Eddie Bondo, Clemens Lamberth, Richard A. Currie & Anthony J. Flemming. (2016) The nematode Caenorhabditis elegans as a tool to predict chemical activity on mammalian development and identify mechanisms influencing toxicological outcome. Scientific Reports 6:1.
Crossref
Thierry Flandre, Sarah Taplin, Stewart Jones & Peter Lloyd. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia
1
14
.
Katharina Mertsch, Martin Will, Werngard Czechtizky, Niels Griesang, Alexander Marker & Jacob Olsen. 2015. Small Molecule Medicinal Chemistry. Small Molecule Medicinal Chemistry
353
377
.
Lars Dalgaard. (2015) Comparison of minipig, dog, monkey and human drug metabolism and disposition. Journal of Pharmacological and Toxicological Methods 74, pages 80-92.
Crossref
Yoshinori Inagaki, Yasuhiko Matsumoto, Masaki Ishii, Keiro Uchino, Hideki Sezutsu & Kazuhisa Sekimizu. (2015) Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein. Scientific Reports 5:1.
Crossref
Carlos Mota & Lorenzo Moroni. 2015. Essentials of 3D Biofabrication and Translation. Essentials of 3D Biofabrication and Translation
187
213
.
Richard Calderone, Nuo Sun, Francoise Gay-Andrieu, William Groutas, Pathum Weerawarna, Sridhar Prasad, Deepu Alex & Dongmei Li. (2014) Antifungal drug discovery: the process and outcomes. Future Microbiology 9:6, pages 791-805.
Crossref
Jinquan Li, Zijian Zhou, Jianghua Feng, Shuhui Cai, Jinhao Gao & Zhong Chen. (2014) NMR-based metabonomic analysis of MnO-embedded iron oxide nanoparticles as potential dual-modal contrast agents. Journal of Nanoparticle Research 16:5.
Crossref
Zhong-Ze Fang, Kristopher W Krausz, Kenjiro Nagaoka, Naoki Tanaka, Krishne Gowda, Shantu G Amin, Gary H Perdew & Frank J Gonzalez. (2014)
In vivo
effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract
. British Journal of Pharmacology 171:7, pages 1735-1746.
Crossref
Christina N Kontoghiorghe. (2014) World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients. World Journal of Methodology 4:3, pages 163.
Crossref
Jinquan Li, Zhenghuan Zhao, Jianghua Feng, Jinhao Gao & Zhong Chen. (2013) Understanding the metabolic fate and assessing the biosafety of MnO nanoparticles by metabonomic analysis. Nanotechnology 24:45, pages 455102.
Crossref
Steve Unger, Wenkui Li, Jimmy Flarakos & Francis L.S. Tse. 2013. Handbook of LC‐MS Bioanalysis. Handbook of LC‐MS Bioanalysis
1
13
.