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Heba Abdelrasheed Allam, Mohamed E. Albakry, Walaa R. Mahmoud, Alessandro Bonardi, Shaimaa A. Moussa, Samy Mohamady, Hatem A. Abdel-Aziz, Claudiu T. Supuran & Hany S. Ibrahim. (2023) Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Alessio Nocentini, Andrea Angeli, Fabrizio Carta, Jean-Yves Winum, Raivis Zalubovskis, Simone Carradori, Clemente Capasso, William A. Donald & Claudiu T. Supuran. (2021) Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 561-580.
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Claudiu T. Supuran & Clemente Capasso. (2020) Antibacterial carbonic anhydrase inhibitors: an update on the recent literature. Expert Opinion on Therapeutic Patents 30:12, pages 963-982.
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Claudiu T. Supuran. (2020) Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery. Expert Opinion on Drug Discovery 15:6, pages 671-686.
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Claudiu T. Supuran. (2020) An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 16:4, pages 297-307.
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Claudiu T. Supuran. (2020) Coumarin carbonic anhydrase inhibitors from natural sources. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1462-1470.
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Hasan Küçükbay, Zeynep Gönül, F. Zehra Küçükbay, Andrea Angeli, Gianluca Bartolucci & Claudiu T. Supuran. (2020) Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1021-1026.
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Manuel A. Llanos, María L. Sbaraglini, María L. Villalba, María D. Ruiz, Carolina Carrillo, Catalina Alba Soto, Alan Talevi, Andrea Angeli, Seppo Parkkila, Claudiu T. Supuran & Luciana Gavernet. (2020) A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 21-30.
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Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
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Claudiu T. Supuran. (2019) Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review. Expert Opinion on Therapeutic Patents 29:10, pages 761-767.
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Giuseppina De Simone. (2019) Targeted treatment of anaerobic cancer. Patent evaluation of US2016279084 and US2017056350. Expert Opinion on Therapeutic Patents 29:1, pages 1-6.
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Pavitra S. Thacker, Pirpasha Shaikh, Andrea Angeli, Mohammed Arifuddin & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1172-1177.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors. Expert Opinion on Investigational Drugs 27:12, pages 963-970.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors and their potential in a range of therapeutic areas. Expert Opinion on Therapeutic Patents 28:10, pages 709-712.
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Claudiu T. Supuran. (2018) Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases. Expert Opinion on Therapeutic Patents 28:10, pages 713-721.
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Claudiu T. Supuran & Clemente Capasso. (2018) Biomedical applications of prokaryotic carbonic anhydrases. Expert Opinion on Therapeutic Patents 28:10, pages 745-754.
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Andrea Angeli & Claudiu T. Supuran. (2018) Treatment of sleep apnea with a combination of a carbonic anhydrase inhibitor and an aldosterone antagonist: a patent evaluation of CA2958110 and IN6616DEN2012. Expert Opinion on Therapeutic Patents 28:10, pages 723-727.
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Vincenzo Alterio, Davide Esposito, Simona Maria Monti, Claudiu T. Supuran & Giuseppina De Simone. (2018) Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 151-157.
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Daniela Vullo, R. Siva Sai Kumar, Andrea Scozzafava, James G. Ferry & Claudiu T. Supuran. (2018) Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 31-36.
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Jed Asher Lusthaus & Ivan Goldberg. (2017) Brimonidine and brinzolamide for treating glaucoma and ocular hypertension; a safety evaluation. Expert Opinion on Drug Safety 16:9, pages 1071-1078.
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E. Matthews & M. G. Hanna. (2017) Dichlorphenamide efficacy in the primary periodic paralyses. Expert Opinion on Orphan Drugs 5:3, pages 285-290.
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Claudiu T. Supuran. (2017) Advances in structure-based drug discovery of carbonic anhydrase inhibitors. Expert Opinion on Drug Discovery 12:1, pages 61-88.
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Claudiu T. Supuran. (2016) Carbonic anhydrase inhibition and the management of neuropathic pain. Expert Review of Neurotherapeutics 16:8, pages 961-968.
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Carrie Lomelino & Robert McKenna. (2016) Carbonic anhydrase inhibitors: a review on the progress of patent literature (2011–2016). Expert Opinion on Therapeutic Patents 26:8, pages 947-956.
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Articles from other publishers (53)
Aditi Redij, Simone Carradori, Andrea Petreni, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2023) Coumarin-pyrazoline Hybrids as Selective Inhibitors of the Tumor-associated
Carbonic Anhydrase IX and XII. Anti-Cancer Agents in Medicinal Chemistry 23:10, pages 1217-1223.
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Heba M. Metwally, Heba Abdelrasheed Allam, Fady Baselious, Alessandro Bonardi, Emad M. Seif, Shaimaa A. Moussa, Ehab Abdel-Latif, Claudiu T. Supuran & Hany S. Ibrahim. (2023) Arylidine extensions of 3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-benzenesulfonamide derivatives: Synthesis, computational simulations and biological evaluation as tumor-associated carbonic anhydrase inhibitors. Bioorganic Chemistry 135, pages 106492.
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Alessio Nocentini, Clemente Capasso & Claudiu T. Supuran. (2023) Carbonic Anhydrase Inhibitors as Novel Antibacterials in the Era of Antibiotic Resistance: Where Are We Now?. Antibiotics 12:1, pages 142.
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Claudiu T. Supuran. 2022. Flavonoids and Phenolics. Flavonoids and Phenolics
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Arittra Bhattacharjee, Ishtiaque Ahammad, Zeshan Mahmud Chowdhury, Keshob Chandra Das, Chaman Ara Keya & Md. Salimullah. (2022) Proteome-Based Investigation Identified Potential Drug Repurposable Small Molecules Against Monkeypox Disease. Molecular Biotechnology.
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Reşit ÇAKMAK. (2022) Synthesis and In Vitro Human Carbonic Anhydrase I and II Inhibition Properties of Some Novel Hydrazone Compounds Containing an Aryl Sulfonate MoietyBir Aril Sülfonat Parçası İçeren Bazı Yeni Hidrazon Bileşiklerinin Sentezi ve İn Vitro İnsan Karbonik Anhidraz I ve II İnhibisyon Özellikleri. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 15:2, pages 659-669.
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Nadia Arif, Zahid Shafiq, Khalid Mahmood, Muhammad Rafiq, Sadia Naz, Sohail Anjum Shahzad, Umar Farooq, Ali H. Bahkali, Abdallah M. Elgorban, Muhammad Yaqub & Ahmed El-Gokha. (2022)
Synthesis, Biological Evaluation, and
In Silico
Studies of Novel Coumarin-Based 4
H
,5
H
-pyrano[3,2-
c
]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors
. ACS Omega 7:32, pages 28605-28617.
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Ashkan Moradi, Hadi Adibi, Vali Akbari & Ali R. Jalalvand. (2022) Developing a novel amperometric method for biosensing of carbonic anhydrase II based on conventional and multi-way chemometric analyses of its inhibition by acetazolamide, dorzolamide and methazolamide. Sensing and Bio-Sensing Research 37, pages 100516.
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Ahmet Gokhan Aggul, Naim Uzun, Muslum Kuzu, Parham Taslimi & Ilhami Gulcin. (2022) Some phenolic natural compounds as carbonic anhydrase inhibitors: An in vitro and in silico study. Archiv der Pharmazie 355:6.
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Dan-Dan Su, Karim Aissou, Yan Zhang, Virginie Gervais, Sebastien Ulrich & Mihail Barboiu. (2022) Squalene–polyethyleneimine–dynamic constitutional frameworks enhancing the enzymatic activity of carbonic anhydrase. Catalysis Science & Technology 12:10, pages 3094-3101.
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Liza Marie C De Guzman, Gerard Q De Guzman & Elena C Borromeo. (2022) Brinzolamide-loaded soft contact lens for ophthalmic delivery. Therapeutic Delivery 13:4, pages 233-247.
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Qiang Yue, Mingfei Cai, Bo Xiao, Qiong Zhan & Chang Zeng. (2021) The Microbiota–Gut–Brain Axis and Epilepsy. Cellular and Molecular Neurobiology 42:2, pages 439-453.
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Ce Dong, Xiongfei Yue, Lin Zhu, Pengzhen Ge, Guozhen Zheng, Zhanying Ye & Baogen Pan. (2022) Curcumin Attenuates Hydrocephalus via Activation of E2F Transcription Factor 4. Cerebrovascular Diseases 51:5, pages 678-685.
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Yara P. Catoira-Boyle, Darrell WuDunn, Louis B. Cantor, John T. Lind, Elizabeth Ann Martin & Steve L. Gerber. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology
2331
2399
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Mudasir Nabi Peerzada, Ernest Hamel, Ruoli Bai, Claudiu T. Supuran & Amir Azam. (2021) Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development. Pharmacology & Therapeutics 225, pages 107860.
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Gaetano Zaccara, Simona Lattanzi & Francesco Brigo. (2021) Which treatment strategy in patients with epilepsy with focal seizures uncontrolled by the first anti-seizure medication?. Epilepsy & Behavior 121, pages 108031.
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Chi-Ren Huang, Hung-Yi Chuang, Nai-Ching Chen, Shu-Fang Chen, Chung-Yao Hsu & Yao-Chung Chuang. (2021) Zonisamide Therapy Reduces Metabolic Consequences and Diminishes Nonalcoholic Fatty Liver Disease in Patients with Epilepsy. Journal of Clinical Medicine 10:15, pages 3380.
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Claudiu T. Supuran & Clemente Capasso. (2021) A Highlight on the Inhibition of Fungal Carbonic Anhydrases as Drug Targets for the Antifungal Armamentarium. International Journal of Molecular Sciences 22:9, pages 4324.
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Cristina Campestre, Viviana De Luca, Simone Carradori, Rossella Grande, Vincenzo Carginale, Andrea Scaloni, Claudiu T. Supuran & Clemente Capasso. (2021) Carbonic Anhydrases: New Perspectives on Protein Functional Role and Inhibition in Helicobacter pylori. Frontiers in Microbiology 12.
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Majid Ali, Syed Majid Bukhari, Asma Zaidi, Farhan A. Khan, Umer Rashid, Neelum Tahir, Baseerat Rabbani & Umar Farooq. (2021) Inhibition Profiling of Urease and Carbonic Anhydrase II by High- Throughput Screening and Molecular Docking Studies of Structurally Diverse Organic Compounds. Letters in Drug Design & Discovery 18:3, pages 299-312.
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Viviana De Luca, Andrea Petreni, Alessio Nocentini, Andrea Scaloni, Claudiu T. Supuran & Clemente Capasso. (2021) Effect of Sulfonamides and Their Structurally Related Derivatives on the Activity of ι-Carbonic Anhydrase from Burkholderia territorii. International Journal of Molecular Sciences 22:2, pages 571.
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Marianne Levon Shahsuvaryan. 2021. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets
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Claudiu T. Supuran. 2021. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications
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131
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Clemente Capasso & Claudiu T. Supuran. 2022. Antiprotozoal Drug Development and Delivery. Antiprotozoal Drug Development and Delivery
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258
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N. I. Kurysheva. (2020) Carbonic Anhydrase Inhibitors in the Treatment of Glaucoma. Review. Part II. Ophthalmology in Russia 17:4, pages 676-682.
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Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar & Claudiu T. Supuran. (2020) Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment. Metabolites 10:10, pages 412.
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Sonia Del Prete, Andrea Angeli, Cynthia Ghobril, Julien Hitce, Cécile Clavaud, Xavier Marat, Claudiu T. Supuran & Clemente Capasso. (2020) Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions. Metabolites 10:1, pages 39.
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Yara P. Catoira-Boyle, Darrell WuDunn, Louis B. Cantor, John T. Lind, Elizabeth Ann Martin & Steve L. Gerber. 2020. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology
1
69
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Karin D. VanBaak, Laura M. Nally, Ryan T. Finigan, Carrie L. Jurkiewicz, Andre M. Burnier, Barry P. Conrad, Morteza Khodaee & Grant S. Lipman. (2019) Wilderness Medical Society Clinical Practice Guidelines for Diabetes Management. Wilderness & Environmental Medicine 30:4, pages S121-S140.
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Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Silvia Bua, Alessio Nocentini, Mohamed A. Abu El-Enin, Mohammed M. Alanazi, Nawaf A. AlSaif, Mohamed M. Hefnawy & Claudiu T. Supuran. (2019) Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives. Bioorganic Chemistry 87, pages 425-431.
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Behnam Rasti, Sargol Mazraedoost, Hanieh Panahi, Mojtaba Falahati & Farnoosh Attar. (2018) New insights into the selective inhibition of the β-carbonic anhydrases of pathogenic bacteria Burkholderia pseudomallei and Francisella tularensis: a proteochemometrics study. Molecular Diversity 23:2, pages 263-273.
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Sonia Del Prete, Silvia Bua, Fatmah Alasmary, Zeid AlOthman, Sylvie Tambutté, Didier Zoccola, Claudiu Supuran & Clemente Capasso. (2019) Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral Stylophora pistillata. Marine Drugs 17:3, pages 146.
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Dilan Ozmen Ozgun, Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, Ilhami Gulcin, Murat Sukuroglu & Claudiu T. Supuran. (2019) Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity. Bioorganic Chemistry 84, pages 511-517.
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Salia Farrokh, John Bon, Michael Erdman & Eljim Tesoro. (2019) Use of Newer Anticonvulsants for the Treatment of Status Epilepticus. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 39:3, pages 297-316.
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Claudiu T. Supuran & Clemente Capasso. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Clemente Capasso. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Martina Buonanno, Simona Maria Monti, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal. European Journal of Medicinal Chemistry 156, pages 430-443.
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Hilde M. H. Braakman & Jakko van Ingen. (2018) Can epilepsy be treated by antibiotics?. Journal of Neurology 265:8, pages 1934-1936.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. Journal of Medicinal Chemistry 61:7, pages 3151-3165.
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Iva Hoffmanová & Daniel Sánchez. (2018) Metabolic acidosis and anaemia associated with dorzolamide in a patient with impaired renal function. British Journal of Clinical Pharmacology 84:4, pages 796-799.
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Marta Ferraroni, Benedetta Cornelio, Janos Sapi, Claudiu T. Supuran & Andrea Scozzafava. (2018) Sulfonamide carbonic anhydrase inhibitors: Zinc coordination and tail effects influence inhibitory efficacy and selectivity for different isoforms. Inorganica Chimica Acta 470, pages 128-132.
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Claudiu Supuran & Clemente Capasso. (2017) An Overview of the Bacterial Carbonic Anhydrases. Metabolites 7:4, pages 56.
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Marta Ferraroni, Laura Lucarini, Emanuela Masini, Mikhail Korsakov, Andrea Scozzafava, Claudiu T. Supuran & Mikhail Krasavin. (2017) 1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads. Bioorganic & Medicinal Chemistry 25:17, pages 4560-4565.
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Himadri Bose & Tulasi Satyanarayana. (2017) Microbial Carbonic Anhydrases in Biomimetic Carbon Sequestration for Mitigating Global Warming: Prospects and Perspectives. Frontiers in Microbiology 8.
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Sonia Del Prete, Daniela Vullo, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2017) Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia. Bioorganic & Medicinal Chemistry 25:13, pages 3555-3561.
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Sonia Del Prete, Daniela Vullo, Didier Zoccola, Sylvie Tambutté, Clemente Capasso & Claudiu T. Supuran. (2017) Kinetic properties and affinities for sulfonamide inhibitors of an α-carbonic anhydrase (CruCA4) involved in coral biomineralization in the Mediterranean red coral Corallium rubrum. Bioorganic & Medicinal Chemistry 25:13, pages 3525-3530.
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Fabrizio Carta, Daniela Vullo, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs. Bioorganic & Medicinal Chemistry 25:9, pages 2569-2576.
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Menshawy A. Mohamed, Alaa A.-M. Abdel-Aziz, Helmy M. Sakr, Adel S. El-Azab, Silvia Bua & Claudiu T. Supuran. (2017) Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties. Bioorganic & Medicinal Chemistry 25:8, pages 2524-2529.
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Joana Smirnovienė, Vytautas Smirnovas & Daumantas Matulis. (2017) Picomolar inhibitors of carbonic anhydrase: Importance of inhibition and binding assays. Analytical Biochemistry 522, pages 61-72.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Manisha Tiwari & Claudiu T. Supuran. (2017) Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. Journal of Medicinal Chemistry 60:6, pages 2456-2469.
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Shikha Kumari, Chandra Bhushan Mishra, Danish Idrees, Amresh Prakash, Rajesh Yadav, Md. Imtaiyaz Hassan & Manisha Tiwari. (2016) Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides. Molecular Diversity 21:1, pages 163-174.
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Giosuè Costa, Maria Concetta Gidaro, Daniela Vullo, Claudiu T. Supuran & Stefano Alcaro. (2016) Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques. Journal of Agricultural and Food Chemistry 64:26, pages 5295-5300.
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Nagwa M. Abdel Gawad, Noha H. Amin, Mohammed T. Elsaadi, Fatma M.M. Mohamed, Andrea Angeli, Viviana De Luca, Clemente Capasso & Claudiu T. Supuran. (2016) Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. Bioorganic & Medicinal Chemistry 24:13, pages 3043-3051.
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