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Expert Opinion on Drug Metabolism & Toxicology Volume 4, 2008 - Issue 2
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Influence of protein–protein interactions on the cellular localization of cytochrome P450

Elzbieta Szczesna-Skorupa Senior Research Biologist University of Illinois at Urbana-Champaign, Department of Molecular and Integrative Physiology, 524 Burrill Hall, 407 S. Goodwin Avenue, Urbana, IL 61801, USA
, PhD &
Byron Kemper Professor University of Illinois at Urbana-Champaign, Department of Molecular and Integrative Physiology, 524 Burrill Hall, 407 S. Goodwin Avenue, Urbana, IL 61801, USA +1 217 333 1146; +1 217 333 1133; [email protected]
, PhD
Pages 123-136 | Published online: 05 Feb 2008

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Michelle C Sangar, Seema Bansal & Narayan G Avadhani. (2010) Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity. Expert Opinion on Drug Metabolism & Toxicology 6:10, pages 1231-1251.
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Ralf Peter Meyer & Marcel Gehlhaus. (2010) A role for CYP in the drug–hormone crosstalk of the brain. Expert Opinion on Drug Metabolism & Toxicology 6:6, pages 675-687.
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Danielle Ireland, Christina Rabeler, TaiXi Gong & Eva-Maria S. Collins. (2022) Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans. Archives of Toxicology 96:12, pages 3233-3243.
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Carlo Barnaba, Bikash Ranjan Sahoo, Thirupathi Ravula, Ilce G. Medina‐Meza, Sang‐Choul Im, G. M. Anantharamaiah, Lucy Waskell & Ayyalusamy Ramamoorthy. (2018) Cytochrome‐P450‐Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs. Angewandte Chemie International Edition 57:13, pages 3391-3395.
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Carlo Barnaba, Bikash Ranjan Sahoo, Thirupathi Ravula, Ilce G. Medina-Meza, Sang-Choul Im, G. M. Anantharamaiah, Lucy Waskell & Ayyalusamy Ramamoorthy. (2018) Cytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs. Angewandte Chemie 130:13, pages 3449-3453.
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Masataka Santoh, Seigo Sanoh, Yuya Ohtsuki, Yoko Ejiri, Yaichiro Kotake & Shigeru Ohta. (2017) Acetaminophen analog N -acetyl- m -aminophenol, but not its reactive metabolite, N -acetyl- p -benzoquinone imine induces CYP3A activity via inhibition of protein degradation. Biochemical and Biophysical Research Communications 486:3, pages 639-644.
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Liu Yang, Ce Shi, Xiaoying Mu, Chao Liu, Ke Shi, Wenjiao Zhu & Qing Yang. (2015) Cloning and expression of a wild eggplant cytochrome P450 gene, StoCYP77A2, involved in plant resistance to Verticillium dahliae. Plant Biotechnology Reports 9:4, pages 167-177.
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Kirsty J. McLean, David Leys & Andrew W. Munro. 2015. Cytochrome P450. Cytochrome P450 261 407 .
Narayan G. Avadhani, Michelle C Sangar, Seema Bansal & Prachi Bajpai. (2011) Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals. The FEBS Journal 278:22, pages 4218-4229.
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Elzbieta Szczesna-Skorupa & Byron Kemper. (2011) The signal-anchor sequence of CYP2C1 inserts into the membrane as a hairpin structure. Biochemical and Biophysical Research Communications 415:2, pages 405-409.
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Satinder K. Gidda, Jay M. Shockey, Mina Falcone, Peter K. Kim, Steven J. Rothstein, David W. Andrews, John M. Dyer & Robert T. Mullen. (2011) Hydrophobic‐Domain‐Dependent Protein–Protein Interactions Mediate the Localization of GPAT Enzymes to ER Subdomains. Traffic 12:4, pages 452-472.
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Elzbieta Szczesna-Skorupa & Byron Kemper. (2011) Progesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 Reductase. Molecular Pharmacology 79:3, pages 340-350.
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Poulomi Acharya, Mingxiang Liao, Juan C. Engel & Maria Almira Correia. (2011) Liver Cytochrome P450 3A Endoplasmic Reticulum-associated Degradation. Journal of Biological Chemistry 286:5, pages 3815-3828.
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Murali Subramanian, Harrison Tam, Helen Zheng & Timothy S. Tracy. (2010) CYP2C9-CYP3A4 Protein-Protein Interactions: Role of the Hydrophobic N Terminus. Drug Metabolism and Disposition 38:6, pages 1003-1009.
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Aki T. Heikkinen, Jukka Mönkkönen & Timo Korjamo. (2010) Determination of permeation resistance distribution in in vitro cell monolayer permeation experiments. European Journal of Pharmaceutical Sciences 40:2, pages 132-142.
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Kenneth Ehrlich. (2009) Predicted Roles of the Uncharacterized Clustered Genes in Aflatoxin Biosynthesis. Toxins 1:1, pages 37-58.
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