Aleksey V. Shchulkin, Pelageya D. Erokhina, Anna V. Goncharenko, Pavel Yu. Mylnikov, Ivan V. Chernykh, Yulia V. Abalenikhina, Maria S. Kotliarova & Elena N. Yakusheva. (2023) Ethylmethylhydroxypyridine Succinate Is an Inhibitor but Not a Substrate of ABCB1 and SLCO1B1. Pharmaceuticals 16:11, pages 1529.
Crossref
Solène Marie, Kayla L. Frost, Raymond K. Hau, Lucy Martinez-Guerrero, Jailyn M. Izu, Cassandra M. Myers, Stephen H. Wright & Nathan J. Cherrington. (2023) Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients. Acta Pharmaceutica Sinica B 13:1, pages 1-28.
Crossref
Jialin Qu, Qiuyue Chen, Tianfu Wei, Ning Dou, Dong Shang & Dan Yuan. (2022) Systematic characterization of Puerariae Flos metabolites in vivo and assessment of its protective mechanisms against alcoholic liver injury in a rat model. Frontiers in Pharmacology 13.
Crossref
Anne‐Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Angelina Kin, Michael Kirstgen, Joachim Geyer, Anja These, Helen Hammer, Oliver Pötz, Albert Braeuning & Stefanie Hessel‐Pras. (2021)
Organic Cation Transporter I and Na
+
/taurocholate Co‐Transporting Polypeptide are Involved in Retrorsine‐ and Senecionine‐Induced Hepatotoxicity in HepaRG cells
. Molecular Nutrition & Food Research 66:2.
Crossref
Van-Long TruongMira JunWoo-Sik Jeong. (2021) Phytochemical and Over-The-Counter Drug Interactions: Involvement of Phase I and II Drug-Metabolizing Enzymes and Phase III Transporters. Journal of Medicinal Food 24:8, pages 786-805.
Crossref
Yanrong Ma, Mingyan Xin, Yuanjie Wen, Huan Wang, Guoqiang Zhang, Jianye Dai & Xin-An Wu. (2021) The utility of endogenous glycochenodeoxycholate-3-sulfate and 4β-hydroxycholesterol to evaluate the hepatic disposition of atorvastatin in rats. Asian Journal of Pharmaceutical Sciences 16:4, pages 519-529.
Crossref
Anne-Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Albert Braeuning & Stefanie Hessel-Pras. (2021) Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells. International Journal of Molecular Sciences 22:8, pages 3821.
Crossref
Guruprasad P. Aithal & Gerd A. Kullak‐Ublick. 2020. The Liver. The Liver
1050
1057
.
Xiaoyang Lu, Lin Liu, Wenya Shan, Limin Kong, Na Chen, Yan Lou & Su Zeng. (2019) The Role of the Sodium-taurocholate Co-transporting Polypeptide (NTCP) and Bile Salt Export Pump (BSEP) in Related Liver Disease. Current Drug Metabolism 20:5, pages 377-389.
Crossref
Yu Chen, Lin Chen, Hong Zhang, Shibo Huang, Yuqing Xiong & Chunhua Xia. (2018) Interaction of Sulfonylureas with Liver Uptake Transporters OATP1B1 and OATP1B3. Basic & Clinical Pharmacology & Toxicology 123:2, pages 147-154.
Crossref
Kathleen M. Giacomini & Huan‐Chieh Chien. 2018. Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants. Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
15
24
.
Abdullah Mayati, Amélie Moreau, Claire Denizot, Bruno Stieger, Yannick Parmentier & Olivier Fardel. (2017) β2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine. European Journal of Pharmaceutical Sciences 106, pages 302-312.
Crossref
Anil M. Deshpande, Debnath Bhuniya, Siddhartha De, Bhavesh Dave, Vinod P. Vyavahare, Santosh H. Kurhade, Sachin R. Kandalkar, Keshav P. Naik, Balasaheb S. Kobal, Rahul D. Kaduskar, Sujay Basu, Vaibhav Jain, Pratima Patil, Sandhya Chaturvedi Joshi, Ganesh Bhat, Amol A. Raje, Satyanarayana Reddy, Jayasagar Gundu, Vamsi Madgula, Suhas Tambe, Prasad Shitole, Dhananjay Umrani, Anita Chugh, Venkata P. Palle & Kasim A. Mookhtiar. (2017) Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia. European Journal of Medicinal Chemistry 133, pages 268-286.
Crossref
Mariline Gameiro, Renata Silva, Carolina Rocha-Pereira, Helena Carmo, Félix Carvalho, Maria Bastos & Fernando Remião. (2017) Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP. Molecules 22:4, pages 600.
Crossref
Elodie Jouan, Marc Le Vée, Claire Denizot, Yannick Parmentier & Olivier Fardel. (2016) Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells. Pharmaceutics 9:4, pages 3.
Crossref
Carsten Uhd Nielsen, Ahmed A. Abdulhussein, Dilan Colak & René Holm. (2016) Polysorbate 20 increases oral absorption of digoxin in wild-type Sprague Dawley rats, but not in mdr1a(-/-) Sprague Dawley rats. International Journal of Pharmaceutics 513:1-2, pages 78-87.
Crossref
Katia Sayyed, Marc Le Vee, Ziad Abdel-Razzak, Elodie Jouan, Bruno Stieger, Claire Denizot, Yannick Parmentier & Olivier Fardel. (2016) Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology 363-364, pages 58-71.
Crossref
Vikram Arya & Jennifer J. Kiser. (2016) Role of Transporters in Drug Development. The Journal of Clinical Pharmacology 56, pages S7-S10.
Crossref
Seung Jun Yang, Bong Jin Kim, Lingxuan Mo & Hyo-Kyung Han. (2016) Alteration of the intravenous and oral pharmacokinetics of valsartan via the concurrent use of gemfibrozil in rats. Biopharmaceutics & Drug Disposition 37:5, pages 245-251.
Crossref
Marilyn E. Morris & Xiaowen Guan. 2016. Drug Delivery. Drug Delivery
62
102
.
Abdullah Mayati, Marc Le Vee, Amélie Moreau, Elodie Jouan, Simon Bucher, Bruno Stieger, Claire Denizot, Yannick Parmentier & Olivier Fardel. (2015) Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochemical Pharmacology 98:4, pages 703-717.
Crossref
Marc Le Vee, Elodie Jouan, Gregory Noel, Bruno Stieger & Olivier Fardel. (2015) Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes. Toxicology in Vitro 29:5, pages 938-946.
Crossref
Bruno Stieger & Gerd A. Kullak‐Ublick. 2015. Antitargets and Drug Safety. Antitargets and Drug Safety
159
172
.
Marc Le Vee, Elodie Jouan, Bruno Stieger, Valérie Lecureur & Olivier Fardel. (2015) Regulation of Human Hepatic Drug Transporter Activity and Expression by Diesel Exhaust Particle Extract. PLOS ONE 10:3, pages e0121232.
Crossref
Marc Le Vée, Elodie Jouan, Claire Denizot, Yannick Parmentier & Olivier Fardel. 2015. Protocols in In Vitro Hepatocyte Research. Protocols in In Vitro Hepatocyte Research
287
302
.
Wen Jin Hua, Wei Xiao Hua, Fu Yong Nan, Wang An Jiang & Chen Yan. (2014) The influence of herbal medicine ursolic acid on the uptake of rosuvastatin mediated by OATP1B1*1a and *5. European Journal of Drug Metabolism and Pharmacokinetics 39:3, pages 221-230.
Crossref
Ryoichi Fujiwara, Saya Takenaka, Mitsuhiro Hashimoto, Tomoya Narawa & Tomoo Itoh. (2014) Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders. Scientific Reports 4:1.
Crossref
Erik Sjögren, Mikael Hedeland, Ulf Bondesson & Hans Lennernäs. (2014) Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs. European Journal of Pharmaceutical Sciences 57, pages 214-223.
Crossref
Simon Bucher, Marc Le Vee, Elodie Jouan & Olivier Fardel. (2014) Regulation of Hepatic Drug Transporter Activity and Expression by Organochlorine Pesticides. Journal of Biochemical and Molecular Toxicology 28:3, pages 119-128.
Crossref
Philip M. E. Probert, Git W. Chung, Simon J. Cockell, Loranne Agius, Pasquale Mosesso, Steven A. White, Fiona Oakley, Colin D. A. Brown & Matthew C. Wright. (2014) Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies. Toxicological Sciences 137:2, pages 350-370.
Crossref
Pär Nordell, Susanne Winiwarter & Constanze Hilgendorf. (2013) Resolving the Distribution–Metabolism Interplay of Eight OATP Substrates in the Standard Clearance Assay with Suspended Human Cryopreserved Hepatocytes. Molecular Pharmaceutics 10:12, pages 4443-4451.
Crossref
Marc Le Vee, Gregory Noel, Elodie Jouan, Bruno Stieger & Olivier Fardel. (2013) Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells. Toxicology in Vitro 27:6, pages 1979-1986.
Crossref
Patricio Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes Georg Bode, Jennifer Bolleyn, Christoph Borner, Jan Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, María Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Chris E. P. Goldring, María José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann-Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens M. Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak-Ublick, Edward L. LeCluyse, Peng Lu, Jennifer Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz-Soja, Patrick McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nussler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan A. Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiss, Agata Widera, Courtney G. Woods, Jinghai James Xu, Kathy M. Yarborough & Jan G. Hengstler. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87:8, pages 1315-1530.
Crossref
Feng You, Jinping Hu, Xue Li & Yan Li. (2013) The elimination of MTC-220, a novel anti-tumor agent of conjugate of paclitaxel and muramyl dipeptide analogue, in rats. Cancer Chemotherapy and Pharmacology 71:6, pages 1453-1462.
Crossref
C Fahrmayr, J König, D Auge, M Mieth, K Münch, J Segrestaa, T Pfeifer, A Treiber & MF Fromm. (2013)
Phase
I
and
II
metabolism and
MRP
2‐mediated export of bosentan in a
MDCKII
‐
OATP1B1‐CYP3A4‐UGT1A1‐MRP2
quadruple‐transfected cell line
. British Journal of Pharmacology 169:1, pages 21-33.
Crossref
Hermann Koepsell. (2013) The SLC22 family with transporters of organic cations, anions and zwitterions. Molecular Aspects of Medicine 34:2-3, pages 413-435.
Crossref
Gregory Noel, Marc Le Vee, Amélie Moreau, Bruno Stieger, Yannick Parmentier & Olivier Fardel. (2013) Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes. European Journal of Pharmaceutical Sciences 49:1, pages 39-50.
Crossref
Andrée-Anne Boivin, Héloïse Cardinal, Azemi Barama, Judith Naud, Vincent Pichette, Marie-Josée Hébert & Michel Roger. (2013) Influence of SLCO1B3 Genetic Variations on Tacrolimus Pharmacokinetics in Renal Transplant Recipients. Drug Metabolism and Pharmacokinetics 28:3, pages 274-277.
Crossref
Yurong Lai. 2013. Transporters in Drug Discovery and Development. Transporters in Drug Discovery and Development
633
674
.
ND Pfeifer, SL Goss, B Swift, G Ghibellini, M Ivanovic, WD Heizer, LM Gangarosa & KLR Brouwer. (2013)
Effect of Ritonavir on
99m
Technetium–Mebrofenin Disposition in Humans: A Semi‐PBPK Modeling and
In Vitro
Approach to Predict Transporter‐Mediated DDIs
. CPT: Pharmacometrics & Systems Pharmacology 2:1, pages 1-10.
Crossref
Geun Hye Jang, Tae Hee Kim, Yunseo Choe, Ahrong Ham & Ji Ha Choi. (2013) Functional characterization of genetic variations in the MDR3 promoter. Biochemical and Biophysical Research Communications 430:4, pages 1312-1318.
Crossref
Bruno Stieger & Gerd A. Kullak-Ublick. 2013. Drug-Induced Liver Disease. Drug-Induced Liver Disease
123
133
.
Alexander V. LyubimovRonald E. White. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
40
.
Karelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston & Aleksandra Galetin. (2012) Simultaneous Assessment of Uptake and Metabolism in Rat Hepatocytes: A Comprehensive Mechanistic Model. Journal of Pharmacology and Experimental Therapeutics 341:1, pages 2-15.
Crossref
Abraham J. Wilhelm, Peer de Graaf, Agnes I. Veldkamp, Jeroen J. W. M. Janssen, Peter C. Huijgens & Eleonora L. Swart. (2012) Population pharmacokinetics of ciclosporin in haematopoietic allogeneic stem cell transplantation with emphasis on limited sampling strategy. British Journal of Clinical Pharmacology 73:4, pages 553-563.
Crossref
Katharine Briggs, Montserrat Cases, David J. Heard, Manuel Pastor, François Pognan, Ferran Sanz, Christof H. Schwab, Thomas Steger-Hartmann, Andreas Sutter, David K. Watson & Jörg D. Wichard. (2012) Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project. International Journal of Molecular Sciences 13:3, pages 3820-3846.
Crossref
C Fahrmayr, J König, D Auge, M Mieth & MF Fromm. (2012) Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple‐transfected MDCK‐OATP1B1‐UGT1A1‐MRP2 cells. British Journal of Pharmacology 165:6, pages 1836-1847.
Crossref
K Mandery, H Glaeser & MF Fromm. (2011) Interaction of innovative small molecule drugs used for cancer therapy with drug transporters. British Journal of Pharmacology 165:2, pages 345-362.
Crossref
Marc Le Vee, Elodie Jouan, Amélie Moreau & Olivier Fardel. (2011) Regulation of drug transporter mRNA expression by interferon-γ in primary human hepatocytes. Fundamental & Clinical Pharmacology 25:1, pages 99-103.
Crossref
Bruno Stieger. 2011. Drug Transporters. Drug Transporters
205
259
.
Hayley S. Brown, Alison J. Wilby, Jane Alder & J. Brian Houston. (2010) Comparative Use of Isolated Hepatocytes and Hepatic Microsomes for Cytochrome P450 Inhibition Studies: Transporter-Enzyme Interplay. Drug Metabolism and Disposition 38:12, pages 2139-2146.
Crossref
Andrée-Anne Boivin, Héloïse Cardinal, Azemi Barama, Vincent Pichette, Marie-Josée Hébert & Michel Roger. (2010) Organic Anion Transporting Polypeptide 1B1 (OATP1B1) and OATP1B3: Genetic Variability and Haplotype Analysis in White Canadians. Drug Metabolism and Pharmacokinetics 25:5, pages 508-515.
Crossref
S-M Huang, L Zhang & K M Giacomini. (2010) The International Transporter Consortium: A Collaborative Group of Scientists From Academia, Industry, and the FDA. Clinical Pharmacology & Therapeutics 87:1, pages 32-36.
Crossref
Tonika Bohnert & Liang‐Shang Gan. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development
91
176
.
Gang Luo, Richard Ridgewell & Thomas Guenthner. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development
467
501
.
Agnès Poirier, Christoph Funk, Jean-Michel Scherrmann & Thierry Lavé. (2009) Mechanistic Modeling of Hepatic Transport from Cells to Whole Body: Application to Napsagatran and Fexofenadine. Molecular Pharmaceutics 6:6, pages 1716-1733.
Crossref
Mathew G. SoarsPeter J. H. WebbornRobert J. Riley. (2009) Impact of Hepatic Uptake Transporters on Pharmacokinetics and Drug−Drug Interactions: Use of Assays and Models for Decision Making in the Pharmaceutical Industry. Molecular Pharmaceutics 6:6, pages 1662-1677.
Crossref
Agnès Poirier, Anne-Christine Cascais, Christoph Funk & Thierry Lavé. (2009) Prediction of pharmacokinetic profile of valsartan in human based on in vitro uptake transport data. Journal of Pharmacokinetics and Pharmacodynamics 36:6, pages 585-611.
Crossref
Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger & Olivier Fardel. (2009) Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes. Drug Metabolism and Disposition 37:11, pages 2228-2235.
Crossref
Christopher Kohl. (2009) Transporters – The View from Industry. Chemistry & Biodiversity 6:11, pages 1988-1999.
Crossref
Agnès Poirier, Anne‐Christine Cascais, Christoph Funk & Thierry Lavé. (2009)
Prediction of Pharmacokinetic Profile of Valsartan in Humans Based on
in vitro
Uptake‐Transport Data
. Chemistry & Biodiversity 6:11, pages 1975-1987.
Crossref
Na Li, Joe Palandra, Olga V. Nemirovskiy & Yurong Lai. (2009) LC−MS/MS Mediated Absolute Quantification and Comparison of Bile Salt Export Pump and Breast Cancer Resistance Protein in Livers and Hepatocytes across Species. Analytical Chemistry 81:6, pages 2251-2259.
Crossref