Citations (78)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Yonghua Xu, Yunting Zou, Shasha Zhou, Miao-Miao Niu, Yan Zhang, Jindong Li, Zhen Xu & Li Yang. (2023) Discovery of potent heat shock protein 90 (Hsp90) inhibitors: structure-based virtual screening, molecular dynamics simulation, and biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
Read now
Read now
Claudio Godoy-Castillo, Nicolas Bravo-Acuña, Gloria Arriagada, Fernando Faunes, Roberto León & Jorge Soto-Delgado. (2021) Identification of the naphthoquinone derivative inhibitors binding site in heat shock protein 90: an induced-fit docking, molecular dynamics and 3D-QSAR study. Journal of Biomolecular Structure and Dynamics 39:16, pages 5977-5987.
Read now
Read now
Thomas Ratajczak, Bryan Kenneth Ward, John Peter Walsh & Carmel Cluning. (2015) Hsp90 as a therapeutic target in endocrinology: current evidence. Research and Reports in Endocrine Disorders 5, pages 141-155.
Read now
Read now
Komal Jhaveri, Stefan O Ochiana, Mark PS Dunphy, John F Gerecitano, Adriana D Corben, Radu I Peter, Yelena Y Janjigian, Erica M Gomes-DaGama, John Koren$suffix/text()$suffix/text(), Shanu Modi & Gabriela Chiosis. (2014) Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions. Expert Opinion on Investigational Drugs 23:5, pages 611-628.
Read now
Read now
Tony Taldone, Hardik J Patel, Alexander Bolaender, Maulik R Patel & Gabriela Chiosis. (2014) Protein chaperones: a composition of matter review (2008 – 2013). Expert Opinion on Therapeutic Patents 24:5, pages 501-518.
Read now
Read now
TaeHun Kim, Gyochang Keum & Ae Nim Pae. (2013) Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives. Expert Opinion on Therapeutic Patents 23:8, pages 919-943.
Read now
Read now
Articles from other publishers (72)
Krishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi & Nupur NagarKrishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi & Nupur Nagar. 2023. Protein-Protein Interactions. Protein-Protein Interactions
43
100
.
Caiwang Peng, Fengyan Zhao, Hengli Li, Ling Li, Yantao Yang & Fang Liu. (2022) HSP90 mediates the connection of multiple programmed cell death in diseases. Cell Death & Disease 13:11.
Crossref
Crossref
Xun Fu, Jiang Liu, Xin Yan, Michael E. DiSanto & Xinhua Zhang. (2022) Heat Shock Protein 70 and 90 Family in Prostate Cancer. Life 12:10, pages 1489.
Crossref
Crossref
Xiaowen Wu, Yi Zou, Kunyu Du, Yi Du, Caleb Kesse Firempong, Yang Yu, Haibing He, Hongfei Liu & Changshan Sun. (2022) Construction and Evaluation of Traceable rhES-QDs-M-MS Protein Delivery System: Sustained-Release Properties, Targeted Effect, and Antitumor Activity. AAPS PharmSciTech 23:6.
Crossref
Crossref
Ahmed Attia Ahmed Abdelmoaty, Ping Zhang, Wen Lin, Ying-juan Fan, Sheng-nan Ye & Jian-hua Xu. (2021) C0818, a novel curcumin derivative, induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function. Acta Pharmacologica Sinica 43:2, pages 446-456.
Crossref
Crossref
Sangeeta Mitra, Angshuman Bagchi & Rakhi Dasgupta. 2022. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
3199
3213
.
Sangeeta Mitra, Angshuman Bagchi & Rakhi Dasgupta. 2021. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
1
15
.
Shuxian Yang, Haiyan Xiao & Li Cao. (2021) Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment. Biomedicine & Pharmacotherapy 142, pages 112074.
Crossref
Crossref
Jing Huang, Xiao-Li Zhu, Ying Wu, Shu-Hua Han, Yan Xie, Su-Fang Yang, Ming Ding & Ping-Sheng Chen. (2021)
Combined effects of low‑dose gambogic acid and NaI
131
in drug‑resistant non‑small cell lung cancer cells
. Oncology Letters 22:2.
Crossref
Crossref
Xiang-ling Chen, Peng Liu, Wei-liang Zhu & Li-guang Lou. (2020) DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer. Acta Pharmacologica Sinica 42:1, pages 132-141.
Crossref
Crossref
Haiying Lu, Qiaodan Zhou, Jun He, Zhongliang Jiang, Cheng Peng, Rongsheng Tong & Jianyou Shi. (2020) Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials. Signal Transduction and Targeted Therapy 5:1.
Crossref
Crossref
Asma Nazar, Ghulam Abbas & Syed Sikander Azam. (2020) Deciphering the Inhibition Mechanism of under Trial Hsp90 Inhibitors and Their Analogues: A Comparative Molecular Dynamics Simulation. Journal of Chemical Information and Modeling 60:8, pages 3812-3830.
Crossref
Crossref
Tony Taldone, Tai Wang, Anna Rodina, Naga Vara Kishore Pillarsetty, Chander S. Digwal, Sahil Sharma, Pengrong Yan, Suhasini Joshi, Piyusha P. Pagare, Alexander Bolaender, Gail J. Roboz, Monica L. Guzman & Gabriela Chiosis. (2020) A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond. Cold Spring Harbor Perspectives in Biology 12:4, pages a034116.
Crossref
Crossref
İrfan Koca, Serhat Yiğitcan, Mehmet Gümüş, Halil Gökce & Yusuf Sert. (2020) A new series of sulfa drugs containing pyrazolyl acylthiourea moiety: Synthesis, experimental and theoretical spectral characterization and molecular docking studies. Journal of Molecular Structure 1204, pages 127479.
Crossref
Crossref
Rui Liu, Xiao-Lu Lu, Xian-Hua Huang, Wei He, Jing-Jing Duan, Jin Zhang & Jian Li. (2020) Complex structure of human Hsp90N and a novel small inhibitor FS5. Nuclear Science and Techniques 31:3.
Crossref
Crossref
Abdullah Hoter, Aseel Othman Alsantely, Edreese Alsharaeh, George Kulik & Islam M. Saadeldin. 2021. Heat Shock Proteins in Human Diseases. Heat Shock Proteins in Human Diseases
53
78
.
Chul Won Yun, Hyung Joo Kim, Ji Ho Lim & Sang Hun Lee. (2019) Heat Shock Proteins: Agents of Cancer Development and Therapeutic Targets in Anti-Cancer Therapy. Cells 9:1, pages 60.
Crossref
Crossref
Kaidi Wang, Xuan Wang, Yiying Hou, Huihui Zhou, Kangsen Mai & Gen He. (2019) Apoptosis of cancer cells is triggered by selective crosslinking and inhibition of receptor tyrosine kinases. Communications Biology 2:1.
Crossref
Crossref
Tai Wang, Anna Rodina, Mark P. Dunphy, Adriana Corben, Shanu Modi, Monica L. Guzman, Daniel T. Gewirth & Gabriela Chiosis. (2019) Chaperome heterogeneity and its implications for cancer study and treatment. Journal of Biological Chemistry 294:6, pages 2162-2179.
Crossref
Crossref
Prathap Somu & Subhankar Paul. 2019. Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Protein 90 in Human Diseases and Disorders
159
182
.
Suman Chatterjee & Timothy F. Burns. 2019. Heat Shock Proteins in Signaling Pathways. Heat Shock Proteins in Signaling Pathways
359
395
.
Xiangling Chen, Peng Liu, Quanren Wang, Yun Li, Li Fu, Haoyu Fu, Jianming Zhu, Zhaoqiang Chen, Weiliang Zhu, Chengying Xie & Liguang Lou. (2018) DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp90-Cdc37 interaction. Cancer Letters 434, pages 70-80.
Crossref
Crossref
Suhasini Joshi, Tai Wang, Thaís L. S. Araujo, Sahil Sharma, Jeffrey L. Brodsky & Gabriela Chiosis. (2018) Adapting to stress — chaperome networks in cancer. Nature Reviews Cancer 18:9, pages 562-575.
Crossref
Crossref
Katia Mangano, Emanuela Mazzon, Maria Sofia Basile, Roberto Di Marco, Placido Bramanti, Santa Mammana, Maria Cristina Petralia, Paolo Fagone & Ferdinando Nicoletti. (2018) Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach. Oncotarget 9:25, pages 17951-17970.
Crossref
Crossref
Abbey D. Zuehlke, Michael A. Moses & Len Neckers. (2017) Heat shock protein 90: its inhibition and function. Philosophical Transactions of the Royal Society B: Biological Sciences 373:1738, pages 20160527.
Crossref
Crossref
Michael A. Moses, Abbey D. Zuehlke & Len Neckers. 2018. Heat Shock Proteins in the Immune System. Heat Shock Proteins in the Immune System
21
40
.
Franciely S. Oliveira, Andreia Ribeiro, Lillian Barros, Ricardo C. Calhelha, João C.M. Barreira, Bogdan D. Junior, Rui M.V. Abreu, Maria Filomena Barreiro & Isabel C.F.R. Ferreira. (2017) Evaluation of Arenaria montana L. hydroethanolic extract as a chemopreventive food ingredient: A case study focusing a dairy product (yogurt). Journal of Functional Foods 38, pages 214-220.
Crossref
Crossref
Suman Chatterjee & Timothy Burns. (2017) Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach. International Journal of Molecular Sciences 18:9, pages 1978.
Crossref
Crossref
Min Ye, Wei Huang, Wen-wei Wu, Yang Liu, Sheng-nan Ye & Jian-hua Xu. (2017) FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition. Oncotarget 8:9, pages 15364-15376.
Crossref
Crossref
Sina Omid Malayeri, Khalil Abnous, Atefeh Arab, Maryam Akaberi, Soghra Mehri, Afshin Zarghi & Razieh Ghodsi. (2017) Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3- g ]quinoline derivatives as potential Hsp90 inhibitors and anticancer agents. Bioorganic & Medicinal Chemistry 25:3, pages 1294-1302.
Crossref
Crossref
Yifan Wang, Hui Liu, Lixia Diao, Adam Potter, Jianhu Zhang, Yawei Qiao, Jing Wang, David A. Proia, Ramesh Tailor, Ritsuko Komaki & Steven H. Lin. (2016) Hsp90 Inhibitor Ganetespib Sensitizes Non–Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation. Clinical Cancer Research 22:23, pages 5876-5886.
Crossref
Crossref
Pablo Zoroquiain, Dana Faingold, Sarah Algahmdi, Natalia Vila, Patrick Logan, Debra-Meghan Sanft, Ana Beatriz Toledo Dias, Sultan Aldrees, Vasco Bravo-Filho, Julia Burnier & Miguel N. Burnier. (2016) Analysis of HSP90 Expression Is Valuable in the Differential Diagnosis of Ocular Surface Squamous Lesions. American Journal of Clinical Pathology 145:3, pages 385-392.
Crossref
Crossref
Jessica A. Hall, Sahithi Seedarala, Huiping Zhao, Gaurav Garg, Suman Ghosh & Brian S. J. Blagg. (2016) Novobiocin Analogues That Inhibit the MAPK Pathway. Journal of Medicinal Chemistry 59:3, pages 925-933.
Crossref
Crossref
Liza Shrestha, Hardik J. Patel & Gabriela Chiosis. (2016) Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease. Cell Chemical Biology 23:1, pages 158-172.
Crossref
Crossref
Jing He, Changwen Ning, Yu Wang, Tianfang Ma, He Huang, Yubin Ge, Jingbo Liu & Yiqun Jiang. (2015) Natural plant flavonoid apigenin directly disrupts Hsp90/Cdc37 complex and inhibits pancreatic cancer cell growth and migration. Journal of Functional Foods 18, pages 10-21.
Crossref
Crossref
Abbey D. Zuehlke, Kristin Beebe, Len Neckers & Thomas Prince. (2015) Regulation and function of the human HSP90AA1 gene. Gene 570:1, pages 8-16.
Crossref
Crossref
Sirintip Boonjaraspinyo, Amornrat Juasook, Thidarut Boonmars, Ratchadawan Aukkanimart, Atit Silsirivanit, Watcharin Loilome, Pranee Sriraj, Zhiliang Wu & Panaratana Ratanasuwan. (2015) A Promising Serum Autoantibody Marker, Anti-Heat Shock Protein 90α, for Cholangiocarcinoma. Asian Pacific Journal of Cancer Prevention 16:14, pages 5779-5785.
Crossref
Crossref
Kristoffer R. Brandvold & Richard I. Morimoto. (2015) The Chemical Biology of Molecular Chaperones—Implications for Modulation of Proteostasis. Journal of Molecular Biology 427:18, pages 2931-2947.
Crossref
Crossref
Hardik J. Patel, Pallav D. Patel, Stefan O. Ochiana, Pengrong Yan, Weilin Sun, Maulik R. Patel, Smit K. Shah, Elisa Tramentozzi, James Brooks, Alexander Bolaender, Liza Shrestha, Ralph Stephani, Paola Finotti, Cynthia Leifer, Zihai Li, Daniel T. Gewirth, Tony Taldone & Gabriela Chiosis. (2015) Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94. Journal of Medicinal Chemistry 58:9, pages 3922-3943.
Crossref
Crossref
Narges Jafarzadeh, Hami Ashraf, Fahimeh Khoshroo, Alireza Sepehri Shamloo, Farzad Bidouei & Kamran Ghaffarzadehgan. (2015) Triple Negative Breast Cancer: Molecular Classification, Prognostic Markers and Targeted Therapies. Razavi International Journal of Medicine 3:2.
Crossref
Crossref
Andrew Anighoro, Dagmar Stumpfe, Kathrin Heikamp, Kristin Beebe, Leonard M. Neckers, Jürgen Bajorath & Giulio Rastelli. (2015) Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome. Journal of Chemical Information and Modeling 55:3, pages 676-686.
Crossref
Crossref
Hirokazu Hirakawa, Hiroshi Fujisawa, Aya Masaoka, Miho Noguchi, Ryoichi Hirayama, Momoko Takahashi, Akira Fujimori & Ryuichi Okayasu. (2015)
The combination of Hsp90 inhibitor 17
AAG
and heavy‐ion irradiation provides effective tumor control in human lung cancer cells
. Cancer Medicine 4:3, pages 426-436.
Crossref
Crossref
Susanta Sekhar Adhikari, Sujan Kumar Mondal & Rajkumar Banerjee. 2015. Heat Shock Protein-Based Therapies. Heat Shock Protein-Based Therapies
219
256
.
Alexandra Manos-Turvey, Jeffrey L. Brodsky & Peter Wipf. 2016. Heat Shock Protein Inhibitors. Heat Shock Protein Inhibitors
81
129
.
Wei Huang, Min Ye, Lian-ru Zhang, Qun-dan Wu, Min Zhang, Jian-hua Xu & Wei Zheng. (2014) FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation. Molecular Cancer 13:1.
Crossref
Crossref
Tony Taldone, Stefan O. Ochiana, Pallav D. Patel & Gabriela Chiosis. (2014) Selective targeting of the stress chaperome as a therapeutic strategy. Trends in Pharmacological Sciences 35:11, pages 592-603.
Crossref
Crossref
Loredana Vesci, Ferdinando Milazzo, Valeria Carollo, Silvia Pace & Giuseppe Giannini. (2014) Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor. International Journal of Oncology.
Crossref
Crossref
Elena Casale, Nadia Amboldi, Maria Gabriella Brasca, Dannica Caronni, Nicoletta Colombo, Claudio Dalvit, Eduard R. Felder, Gianpaolo Fogliatto, Arturo Galvani, Antonella Isacchi, Paolo Polucci, Laura Riceputi, Francesco Sola, Carlo Visco, Fabio Zuccotto & Francesco Casuscelli. (2014) Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors. Bioorganic & Medicinal Chemistry 22:15, pages 4135-4150.
Crossref
Crossref
XIAOXIA WANG, MEIJUAN CHEN, JING ZHOU & XU ZHANG. (2014) HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy. International Journal of Oncology 45:1, pages 18-30.
Crossref
Crossref
Julia Slotta-Huspenina, Karl-Friedrich Becker, Marcus Feith, Axel Walch & Rupert Langer. (2014) Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus. Cancers 6:3, pages 1382-1393.
Crossref
Crossref
Enken Drecoll, Ulrich Nitsche, Karina Bauer, Sabina Berezowska, Julia Slotta-Huspenina, Robert Rosenberg & Rupert Langer. (2014) Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma. International Journal of Colorectal Disease 29:6, pages 663-671.
Crossref
Crossref
Christiane Fischer, Sandra Vomstein & Thomas Mindt. (2014) A Bombesin-Shepherdin Radioconjugate Designed for Combined Extra- and Intracellular Targeting. Pharmaceuticals 7:6, pages 662-675.
Crossref
Crossref
David J. Newman & Gordon M. Cragg. 2014. Natural Products. Natural Products
397
411
.
David J. Newman & Gordon M. Cragg. 2014. Natural Products in Medicinal Chemistry. Natural Products in Medicinal Chemistry
1
42
.
Stefan O. Ochiana, Tony Taldone & Gabriela Chiosis. 2014. The Molecular Chaperones Interaction Networks in Protein Folding and Degradation. The Molecular Chaperones Interaction Networks in Protein Folding and Degradation
151
183
.
Jing He, Xiaojia Niu, Cheng Hu, Hongyi Zhang, Yingjie Guo, Yubin Ge, Guangyi Wang & Yiqun Jiang. (2013) Expression and purification of recombinant NRL-Hsp90α and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening. Protein Expression and Purification 92:1, pages 119-127.
Crossref
Crossref
Swee Sharp, Jenny Howes & Paul Workman. 2013. Inhibitors of Molecular Chaperones as Therapeutic Agents. Inhibitors of Molecular Chaperones as Therapeutic Agents
126
157
.
Xiaoping Sun, Jillian A. Bristol, Satoko Iwahori, Stacy R. Hagemeier, Qiao Meng, Elizabeth A. Barlow, Joyce D. Fingeroth, Vera L. Tarakanova, Robert F. Kalejta & Shannon C. Kenney. (2013) Hsp90 Inhibitor 17-DMAG Decreases Expression of Conserved Herpesvirus Protein Kinases and Reduces Virus Production in Epstein-Barr Virus-Infected Cells. Journal of Virology 87:18, pages 10126-10138.
Crossref
Crossref
Ralf J. Ludwig, Kathrin Kalies, Jörg Köhl, Detlef Zillikens & Enno Schmidt. (2013) Emerging treatments for pemphigoid diseases. Trends in Molecular Medicine 19:8, pages 501-512.
Crossref
Crossref
Sabina Berezowska, Alexander Novotny, Karina Bauer, Annette Feuchtinger, Julia Slotta-Huspenina, Karen Becker, Rupert Langer & Axel Walch. (2013) Association between HSP90 and Her2 in Gastric and Gastroesophageal Carcinomas. PLoS ONE 8:7, pages e69098.
Crossref
Crossref
Gianpaolo Fogliatto, Laura Gianellini, Maria G. Brasca, Elena Casale, Dario Ballinari, Marina Ciomei, Anna Degrassi, Anna De Ponti, Massimiliano Germani, Marco Guanci, Mauro Paolucci, Paolo Polucci, Micaela Russo, Francesco Sola, Barbara Valsasina, Carlo Visco, Fabio Zuccotto, Daniele Donati, Eduard Felder, Enrico Pesenti, Arturo Galvani, Sergio Mantegani & Antonella Isacchi. (2013) NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases. Clinical Cancer Research 19:13, pages 3520-3532.
Crossref
Crossref
Rebecca Johnson, Nirupama Sabnis, Walter McConathy & Andras Lacko. (2013) The Potential Role of Nanotechnology in Therapeutic Approaches for Triple Negative Breast Cancer. Pharmaceutics 5:4, pages 353-370.
Crossref
Crossref
Jun Fu, Dimpy Koul, Jun Yao, Shuzhen Wang, Ying Yuan, Howard Colman, Erik. P. Sulman, Frederick. F. Lang & W.K. Alfred Yung. (2013) Novel HSP90 Inhibitor NVP-HSP990 Targets Cell-Cycle Regulators to Ablate Olig2-Positive Glioma Tumor–Initiating Cells. Cancer Research 73:10, pages 3062-3074.
Crossref
Crossref
Tony Taldone, Anna Rodina, Erica M DaGama Gomes, Matthew Riolo, Hardik J Patel, Raul Alonso-Sabadell, Danuta Zatorska, Maulik R Patel, Sarah Kishinevsky & Gabriela Chiosis. (2013) Synthesis and evaluation of cell-permeable biotinylated PU-H71 derivatives as tumor Hsp90 probes. Beilstein Journal of Organic Chemistry 9, pages 544-556.
Crossref
Crossref
Jana Franke, Simone Eichner, Carsten Zeilinger & Andreas Kirschning. (2013) Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy. Natural Product Reports 30:10, pages 1299.
Crossref
Crossref
Monica L. Guzman, Maeve A. Lowery, Tony Taldone, John KorenIIIIII, Erica DaGama Gomes & Gabriela Chiosis. 2013. Cell Death Signaling in Cancer Biology and Treatment. Cell Death Signaling in Cancer Biology and Treatment
181
203
.
Nicholas G.M. Davies, Helen Browne, Ben Davis, Martin J. Drysdale, Nicolas Foloppe, Stephanie Geoffrey, Ben Gibbons, Terance Hart, Roderick Hubbard, Michael Rugaard Jensen, Howard Mansell, Andrew Massey, Natalia Matassova, Jonathan D. Moore, James Murray, Robert Pratt, Stuart Ray, Alan Robertson, Stephen D. Roughley, Joseph Schoepfer, Kirsten Scriven, Heather Simmonite, Stephen Stokes, Allan Surgenor, Paul Webb, Mike Wood, Lisa Wright & Paul Brough. (2012) Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorganic & Medicinal Chemistry 20:22, pages 6770-6789.
Crossref
Crossref
Komal Jhaveri, Tony Taldone, Shanu Modi & Gabriela Chiosis. (2012) Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:3, pages 742-755.
Crossref
Crossref
Paolo Swuec & David J. Barlow. (2012) Prediction of inhibitory activities of Hsp90 inhibitors. Bioorganic & Medicinal Chemistry 20:1, pages 408-414.
Crossref
Crossref
Sophie E. Jackson. 2013. Molecular Chaperones. Molecular Chaperones
155
240
.
François Vallée, Chantal Carrez, Fabienne Pilorge, Alain Dupuy, Annick Parent, Luc Bertin, Fabienne Thompson, Paul Ferrari, Florence Fassy, Annabelle Lamberton, Anne Thomas, Rosalia Arrebola, Stéphane Guerif, Alexandre Rohaut, Victor Certal, Jean-Marie Ruxer, Cécile Delorme, Alain Jouanen, Jacques Dumas, Claudine Grépin, Cécile Combeau, Hélène Goulaouic, Norbert Dereu, Vincent Mikol, Patrick Mailliet & Hervé Minoux. (2011)
Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-
c
]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone
. Journal of Medicinal Chemistry 54:20, pages 7206-7219.
Crossref
Crossref
Tony Taldone, Erica M. Gomes-DaGama, Hongliang Zong, Siddhartha Sen, Mary L. Alpaugh, Danuta Zatorska, Raul Alonso-Sabadell, Monica L. Guzman & Gabriela Chiosis. (2011) Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. Bioorganic & Medicinal Chemistry Letters 21:18, pages 5347-5352.
Crossref
Crossref