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Expert Review of Molecular Diagnostics Volume 8, 2008 - Issue 5
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Special Report

Tumor M2 pyruvate kinase: a tumor marker and its clinical application in gastrointestinal malignancy

Philip D Hardt Third Medical Department and Policlinic, University Hospital Giessen and Marburg, Giessen Site, Rodthohl 6, D-35392, Giessen, Germany. [email protected]
&
Nils Ewald Third Medical Department and Policlinic, University Hospital Giessen and Marburg, Giessen Site, Rodthohl 6, D-35392, Giessen, Germany. [email protected]
Pages 579-585 | Published online: 09 Jan 2014

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Cristiana Pistol Tanase, Monica Neagu, Radu Albulescu, Eleonora Codorean & Simona Olimpia Dima. (2009) Biomarkers in the diagnosis and early detection of pancreatic cancer. Expert Opinion on Medical Diagnostics 3:5, pages 533-546.
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Articles from other publishers (18)

Sung Soo Ahn, Hye Min Kim & Younhee Park. (2022) Assessment of disease activity in patients with rheumatoid arthritis using plasma tumour M2-pyruvate kinase test. Frontiers in Immunology 13.
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Aneta L. Zygulska & Piotr Pierzchalski. (2022) Novel Diagnostic Biomarkers in Colorectal Cancer. International Journal of Molecular Sciences 23:2, pages 852.
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Haipeng Zhu & Xiaojun Liu. (2021) Advances of Tumorigenesis, Diagnosis at Early Stage, and Cellular Immunotherapy in Gastrointestinal Malignancies. Frontiers in Oncology 11.
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Hamid Kalantari, Mahsa Khodadoostan, Majid Yaran & Abdolrasoul Tavakoli. (2020) Diagnostic value of pyruvate kinase isoenzyme type M2 in colon cancer proven with colonoscopy. Advanced Biomedical Research 9:1, pages 76.
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Holger Husi, Marco Fernandes, Richard Skipworth, Janice Miller, Andrew Cronshaw, Kenneth Fearon & James Ross. (2019) Identification of diagnostic upper gastrointestinal cancer tissue type‑specific urinary biomarkers. Biomedical Reports.
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Farid Ahmad Siddiqui, Gopinath Prakasam, Shilpi Chattopadhyay, Asad Ur Rehman, Rayees Ahmad Padder, Mohammad Afaque Ansari, Rasha Irshad, Kailash Mangalhara, Rameshwar N. K. Bamezai, Mohammad Husain, Syed Mansoor Ali & Mohammad Askandar Iqbal. (2018) Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition. Scientific Reports 8:1.
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Anthony KC Chan, Jason IE Bruce & Ajith K Siriwardena. (2016) Glucose metabolic phenotype of pancreatic cancer. World Journal of Gastroenterology 22:12, pages 3471-3485.
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Goran Hamid Mohammad, S. W. M. Olde Damink, Massimo Malago, Dipok Kumar Dhar & Stephen P. Pereira. (2016) Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome. PLOS ONE 11:3, pages e0151635.
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Adam Rzechonek, Aleksandra Kaminska, Piotr Mamczur, Arkadiusz Drapiewski & Władysław Budzynski. 2017. Pathobiology of Pulmonary Disorders. Pathobiology of Pulmonary Disorders 51 57 .
Harsimran Kaur, Sharda Sidhu & Vasudha Sambyal. (2015) MCP-1, dM2-PK and traditional risk factors for coronary artery disease among type II diabetes patients. International Journal of Diabetes in Developing Countries 35:S3, pages 323-332.
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Kim Y. C. Fung, Bruce Tabor, Michael J. Buckley, Ilka K. Priebe, Leanne Purins, Celine Pompeia, Gemma V. Brierley, Trevor Lockett, Peter Gibbs, Jeanne Tie, Paul McMurrick, James Moore, Andrew Ruszkiewicz, Edouard Nice, Timothy E. Adams, Antony Burgess & Leah J. Cosgrove. (2015) Blood-Based Protein Biomarker Panel for the Detection of Colorectal Cancer. PLOS ONE 10:3, pages e0120425.
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Zongwei Li, Peng Yang & Zhuoyu Li. (2014) The multifaceted regulation and functions of PKM2 in tumor progression. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1846:2, pages 285-296.
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Daniel Fatela-Cantillo, Antonio Fernandez-Suarez, Miguel Alonso Marin Moreno, Juan Jesus Puente Gutierrez & Jose Miguel Diaz Iglesias. (2012) Prognostic value of plasmatic tumor M2 pyruvate kinase and carcinoembryonic antigen in the survival of colorectal cancer patients. Tumor Biology 33:3, pages 825-832.
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Mohd Askandar Iqbal & Rameshwar N. K. Bamezai. (2012) Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin. PLoS ONE 7:5, pages e36764.
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Ruth M Ayling. (2011) New faecal tests in gastroenterology. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 49:1, pages 44-54.
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Holger Husi, Nathan Stephens, Andrew Cronshaw, Alisdair MacDonald, Iain Gallagher, Carolyn Greig, Kenneth C. H. Fearon & James A. Ross. (2011) Proteomic analysis of urinary upper gastrointestinal cancer markers. PROTEOMICS - Clinical Applications 5:5-6, pages 289-299.
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Vibhor Gupta, Ponnusamy Kalaiarasan, Mohammad Faheem, Nishant Singh, Mohammad Askandar Iqbal & Rameshwar N.K. Bamezai. (2010) Dominant Negative Mutations Affect Oligomerization of Human Pyruvate Kinase M2 Isozyme and Promote Cellular Growth and Polyploidy. Journal of Biological Chemistry 285:22, pages 16864-16873.
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Cristiana Pistol Tanase, Monica Neagu, Radu Albulescu & Mihail Eugen Hinescu. 2010. 145 180 .

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