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Review

Vaccine adjuvant technology: from mechanistic concepts to practical applications

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Pages 327-335 | Published online: 09 Jan 2014

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Raquel Da Costa Martins, Juan M Irache & Carlos Gamazo. (2012) Acellular vaccines for ovine brucellosis: a safer alternative against a worldwide disease. Expert Review of Vaccines 11:1, pages 87-95.
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H. Oya Alpar. (2003) Strategies for Vaccine Delivery. Journal of Drug Targeting 11:8-10, pages 459-461.
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Moein Masjedi, Talieh Montahaei, Zeinab Sharafi & Atefeh Jalali. (2022) Pulmonary vaccine delivery: An emerging strategy for vaccination and immunotherapy. Journal of Drug Delivery Science and Technology 69, pages 103184.
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Bingfeng Zuo, Han Qi, Zhen Lu, Lu Chen, Bo Sun, Rong Yang, Yang Zhang, Zhili Liu, Xianjun Gao, Abin You, Li Wu, Renwei Jing, Qibing Zhou & HaiFang Yin. (2020) Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice. Nature Communications 11:1.
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Prasanna Lakshmi Abbaraju, Manasi Jambhrunkar, Yannan Yang, Yang Liu, Yao Lu & Chengzhong Yu. (2018) Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses. Chemical Communications 54:16, pages 2020-2023.
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Quan-Jiang Song, Xiao-Gang Weng, Dong-Jie Cai, Wang Zhang & Jiu-Feng Wang. (2016) Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28–4-1BB Signaling in Bovine PBMCs. PLOS ONE 11:9, pages e0162791.
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Nicole Hartwig Trier, Anne Mortensen, Annette Schiolborg & Tina Friis. 2015. Peptide Antibodies. Peptide Antibodies 109 126 .
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Darren R. Flower. 2013. Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines 155 180 .
Juliana De Souza Rebouças, Juan Manuel Irache, Ana I. Camacho, Irene Esparza, Victoria del Pozo, María L. Sanz, Marta Ferrer & Carlos Gamazo. (2012) Development of poly(anhydride) nanoparticles loaded with peanut proteins: The influence of preparation method on the immunogenic properties. European Journal of Pharmaceutics and Biopharmaceutics 82:2, pages 241-249.
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Alexander Batista-Duharte, Erik B. Lindblad & Ernesto Oviedo-Orta. (2011) Progress in understanding adjuvant immunotoxicity mechanisms. Toxicology Letters 203:2, pages 97-105.
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Luciana V. Carvalho, Rita de C. Ruiz, Karina Scaramuzzi, Eliana B. Marengo, Jivaldo R. Matos, Denise V. Tambourgi, Marcia C.A. Fantini & Osvaldo A. Sant’Anna. (2010) Immunological parameters related to the adjuvant effect of the ordered mesoporous silica SBA-15. Vaccine 28:50, pages 7829-7836.
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Sergio Regodón, Asunción Ramos, Sara Morgado, Raquel Tarazona, Pedro Martín-Palomino, Juan A. Rosado & María del Prado Míguez. (2009) Melatonin enhances the immune response to vaccination against A1 and C strains of Dichelobacter nodosus. Vaccine 27:10, pages 1566-1570.
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J.G.M. Heldens, J.R. Patel, N. Chanter, G.J. ten Thij, M. Gravendijck, V.E.J.C. Schijns, A. Langen & Th.P.M. Schetters. (2008) Veterinary vaccine development from an industrial perspective. The Veterinary Journal 178:1, pages 7-20.
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VIRGIL E.J.C. SCHIJNS, JAGDEV SHARMA & IAN TARPEY. 2008. Avian Immunology. Avian Immunology 373 393 .
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Denise Morais da Fonseca, Célio Lopes Silva, Marina Oliveira e Paula, Edson Garcia Soares, Gilles Marchal, Cynthia Horn & Vânia Luiza Deperon Bonato. (2007) Increased levels of interferon-? primed by culture filtrate proteins antigen and CpG-ODN immunization do not confer significant protection against Mycobacterium tuberculosis infection. Immunology 121:4, pages 508-517.
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Jose A. Chabalgoity, Adriana Baz, Analía Rial & Sofía Grille. (2007) The relevance of cytokines for development of protective immunity and rational design of vaccines. Cytokine & Growth Factor Reviews 18:1-2, pages 195-207.
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Theo Jansen, Marij P.M. Hofmans, Marc J.G. Theelen, Frans Manders & Virgil E.J.C. Schijns. (2006) Structure- and oil type-based efficacy of emulsion adjuvants. Vaccine 24:26, pages 5400-5405.
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Elizabeth M. Sutkowski & Marion F. Gruber. 2006. Immunopotentiators in Modern Vaccines. Immunopotentiators in Modern Vaccines 343 359 .
Sergio Regodón, Pedro Martín-Palomino, Rafael Fernández-Montesinos, Juan Luis Herrera, M. Pilar Carrascosa-Salmoral, Segundo Píriz, Santiago Vadillo, Juan M. Guerrero & David Pozo. (2005) The use of melatonin as a vaccine agent. Vaccine 23:46-47, pages 5321-5327.
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Michael Gough, Marka Crittenden, Uma Thanarajasingam, Luis Sanchez-Perez, Jill Thompson, Dragan Jevremovic & Richard Vile. (2005) Gene Therapy to Manipulate Effector T Cell Trafficking to Tumors for Immunotherapy. The Journal of Immunology 174:9, pages 5766-5773.
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Frank R. Brennan & Gordon Dougan. (2005) Non-clinical safety evaluation of novel vaccines and adjuvants: new products, new strategies. Vaccine 23:24, pages 3210-3222.
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Karla M. Lima, Sandra Aparecida dos Santos, José M. RodriguesJr.Jr. & Célio L. Silva. (2004) Vaccine adjuvant: it makes the difference. Vaccine 22:19, pages 2374-2379.
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Yoshiki Kuroda, Dina C Nacionales, Jun Akaogi, Westley H Reeves & Minoru Satoh. (2004) Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine. Biomedicine & Pharmacotherapy 58:5, pages 325-337.
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