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SPECIAL FOCUS: RNA Vaccines - Review

Electroporation-enhanced delivery of nucleic acid vaccines

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Mina Aleksanyan, Hammad A. Faizi, Maria-Anna Kirmpaki, Petia M. Vlahovska, Karin A. Riske & Rumiana Dimova. (2023) Assessing membrane material properties from the response of giant unilamellar vesicles to electric fields. Advances in Physics: X 8:1.
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Akon Higuchi, Tzu-Cheng Sung, Ting Wang, Qing-Dong Ling, S. Suresh Kumar, Shih-Tien Hsu & Akihiro Umezawa. (2023) Material Design for Next-Generation mRNA Vaccines Using Lipid Nanoparticles. Polymer Reviews 63:2, pages 394-436.
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Elnaz Faghfuri, Farhad Pourfarzi, Amir Hossein Faghfouri, Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh & Behzad Baradaran. (2021) Recent developments of RNA-based vaccines in cancer immunotherapy. Expert Opinion on Biological Therapy 21:2, pages 201-218.
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Peter Pushko, Igor S. Lukashevich, Scott C. Weaver & Irina Tretyakova. (2016) DNA-launched live-attenuated vaccines for biodefense applications. Expert Review of Vaccines 15:9, pages 1223-1234.
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Lei Li & Nikolai Petrovsky. (2016) Molecular mechanisms for enhanced DNA vaccine immunogenicity. Expert Review of Vaccines 15:3, pages 313-329.
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Ibrahim A. Aljuffali, Yin-Ku Lin & Jia-You Fang. (2016) Noninvasive approach for enhancing small interfering RNA delivery percutaneously. Expert Opinion on Drug Delivery 13:2, pages 265-280.
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Articles from other publishers (41)

Jeffrey M. Skolnik & Matthew P. Morrow. (2023) Vaccines for HPV-associated diseases. Molecular Aspects of Medicine 94, pages 101224.
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Sthefany Pagliari, Barbara Dema, Alexandra Sanchez-Martinez, Gerardo Montalvo Zurbia-Flores & Christine S. Rollier. (2023) DNA Vaccines: History, Molecular Mechanisms and Future Perspectives. Journal of Molecular Biology 435:23, pages 168297.
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Ted Mau, Milan R. AminPeter C. BelafskySimon R. Best, Aaron D. Friedman, Adam M. KleinDavid G. Lott, Randal C. Paniello, Seth M. PranskyNabil F. SabaTamara HowardMichael DallasAditya PatelMatthew P. MorrowJeffrey M. Skolnik. (2023) Interim Results of a Phase 1/2 Open‐Label Study of INO ‐3107 for HPV ‐6 and/or HPV ‐11‐Associated Recurrent Respiratory Papillomatosis . The Laryngoscope 133:11, pages 3087-3093.
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Whitney Tran, Cormak Weeks, Yatish Rane & Jeremy Marston. (2023) Effect of nozzle shape and applied load on jet injection efficiency. Journal of Drug Delivery Science and Technology 86, pages 104640.
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Priyanshi Goyal & Rishabha Malviya. (2023) Advancement in Polymer-based Carrier for DNA Vaccine. Current Pharmaceutical Design 29:26, pages 2062-2077.
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Nicholas J. Tursi, Ziyang Xu, Daniel W. Kulp & David B. Weiner. (2023) Gene‐encoded nanoparticle vaccine platforms for in vivo assembly of multimeric antigen to promote adaptive immunity. WIREs Nanomedicine and Nanobiotechnology 15:4.
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Sofia K. Georgiou-Siafis, Androulla N. Miliotou, Charikleia Ntenti, Ioannis S. Pappas & Lefkothea C. Papadopoulou. (2022) An Innovative PTD-IVT-mRNA Delivery Platform for CAR Immunotherapy of ErbB(+) Solid Tumor Neoplastic Cells. Biomedicines 10:11, pages 2885.
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Denis N. Kisakov, Lyubov A. Orlova, Сергей V. Sharabrin, Andrey P. Rudometov, Maria B. Borgoyakova, Ekaterina V. Starostina, Larisa I. Karpenko & Alexander A. Ilyichev. (2022) Delivery of a DNA vaccine encoding SARS-CoV-2 receptor-binding domain (RBD) by electroporation. Medical academic journal 2:2, pages 191-196.
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Katarzyna Rakoczy, Monika Kisielewska, Mikołaj Sędzik, Laura Jonderko, Julia Celińska, Natalia Sauer, Wojciech Szlasa, Jolanta Saczko, Vitalij Novickij & Julita Kulbacka. (2022) Electroporation in Clinical Applications—The Potential of Gene Electrotransfer and Electrochemotherapy. Applied Sciences 12:21, pages 10821.
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Elizabeth M. Parzych, Jianqiu Du, Ali R. Ali, Katherine Schultheis, Drew Frase, Trevor R. F. Smith, Jiayan Cui, Neethu Chokkalingam, Nicholas J. Tursi, Viviane M. Andrade, Bryce M. Warner, Ebony N. Gary, Yue Li, Jihae Choi, Jillian Eisenhauer, Igor Maricic, Abhijeet Kulkarni, Jacqueline D. Chu, Gabrielle Villafana, Kim Rosenthal, Kuishu Ren, Joseph R. Francica, Sarah K. Wootton, Pablo Tebas, Darwyn Kobasa, Kate E. Broderick, Jean D. Boyer, Mark T. Esser, Jesper Pallesen, Dan W. Kulp, Ami Patel & David B. Weiner. (2022) DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nature Communications 13:1.
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Florian Simon, Mansur Duran, Waseem Garabet, Hubert Schelzig, Michael Jacobs & Alexander Gombert. (2022) Gene Therapy of Chronic Limb-Threatening Ischemia: Vascular Medical Perspectives. Journal of Clinical Medicine 11:5, pages 1282.
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Tynisha S. Rafael, Jossie Rotman, Oscar R. Brouwer, Henk G. van der Poel, Constantijne H. Mom, Gemma G. Kenter, Tanja D. de Gruijl & Ekaterina S. Jordanova. (2022) Immunotherapeutic Approaches for the Treatment of HPV-Associated (Pre-)Cancer of the Cervix, Vulva and Penis. Journal of Clinical Medicine 11:4, pages 1101.
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Samo Mahnič-Kalamiza & Damijan Miklavčič. 2022. Pulsed Electric Fields Technology for the Food Industry. Pulsed Electric Fields Technology for the Food Industry 107 141 .
Androulla N. Miliotou, Ioannis S. Pappas, George Spyroulias, Efthimia Vlachaki, Asterios S. Tsiftsoglou, Ioannis S. Vizirianakis & Lefkothea C. Papadopoulou. (2021) Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders. Molecular Therapy - Nucleic Acids 26, pages 694-710.
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Dalinda Eusébio, Ana R. Neves, Diana Costa, Swati Biswas, Gilberto Alves, Zhengrong Cui & Ângela Sousa. (2021) Methods to improve the immunogenicity of plasmid DNA vaccines. Drug Discovery Today 26:11, pages 2575-2592.
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Srilatha Edupuganti, Stephen C. De Rosa, Marnie Elizaga, Yiwen Lu, Xue Han, Yunda Huang, Edith Swann, Laura Polakowski, Spyros A. Kalams, Michael Keefer, Janine Maenza, Megan C. Wise, Jian Yan, Matthew Morrow, Amir Khan, Jean Boyer, Laurent Humeau, Scott White, Niranjan Sardesai, Mark Bagarazzi, Peter Gilbert, James Kublin, Lawrence Corey & David Weiner. (2020) Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP® DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults. Vaccines 8:4, pages 741.
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Shuqin Xu, Kunpeng Yang, Rose Li & Lu Zhang. (2020) mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection. International Journal of Molecular Sciences 21:18, pages 6582.
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Yasmin Hasan, Larissa Furtado, Ana Tergas, Nita Lee, Rebecca Brooks, Anne McCall, Daniel Golden, Shruti Jolly, Gini Fleming, Matthew Morrow, Kimberly Kraynyak, Albert Sylvester, Fauzia Arif, Matt Levin, David Schwartz, Jean Boyer, Jeffrey Skolnik, Mark Esser, Rakesh Kumar, Mark Bagarazzi, Ralph Weichselbaum & Michael Spiotto. (2020) A Phase 1 Trial Assessing the Safety and Tolerability of a Therapeutic DNA Vaccination Against HPV16 and HPV18 E6/E7 Oncogenes After Chemoradiation for Cervical Cancer. International Journal of Radiation Oncology*Biology*Physics 107:3, pages 487-498.
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Zohreh Jahanafrooz, Behzad Baradaran, Jafar Mosafer, Mahmoud Hashemzaei, Tayebeh Rezaei, Ahad Mokhtarzadeh & Michael R. Hamblin. (2020) Comparison of DNA and mRNA vaccines against cancer. Drug Discovery Today 25:3, pages 552-560.
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Zhenzhen Ding, Hua Zhu, Laiming Mo, Xiangyun Li, Rui Xu, Tian Li, Liang Zhao, Yi Ren, Yunsheng Xu & Rongying Ou. (2019) FLT3L and granulocyte macrophage colony-stimulating factor enhance the anti-tumor and immune effects of an HPV16 E6/E7 vaccine. Aging 11:24, pages 11893-11904.
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Jonathan A. Simmons, Justin Davis, James Thomas, Juan Lopez, Andrew Le Blanc, Haley Allison, Haley Slook, Paul Lewis, Joshua Holtz, Paul Fisher, Kate E. Broderick & Jeremy O. Marston. (2019) Characterization of skin blebs from intradermal jet injection: Ex-vivo studies. Journal of Controlled Release 307, pages 200-210.
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Qingfu Zhu, Megan Hamilton, Bryan Vasquez & Mei He. (2019) 3D-printing enabled micro-assembly of a microfluidic electroporation system for 3D tissue engineering. Lab on a Chip 19:14, pages 2362-2372.
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Pablo Tebas, Kimberly A Kraynyak, Ami Patel, Joel N Maslow, Matthew P Morrow, Albert J Sylvester, Dawson Knoblock, Elisabeth Gillespie, Dinah Amante, Trina Racine, Trevor McMullan, Moonsup Jeong, Christine C Roberts, Young K Park, Jean Boyer, Kate E Broderick, Gary P Kobinger, Mark Bagarazzi, David B Weiner, Niranjan Y Sardesai & Scott M White. (2019) Intradermal SynCon® Ebola GP DNA Vaccine Is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers. The Journal of Infectious Diseases 220:3, pages 400-410.
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Jeremy O. Marston & Carla M.R. Lacerda. (2019) Characterization of jet injection efficiency with mouse cadavers. Journal of Controlled Release 305, pages 101-109.
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Jingjing Jiang, Stephanie J. Ramos, Preeti Bangalore, Paul Fisher, Kristine Germar, Brian K. Lee, Dan Williamson, Andrea Kemme, Eric Schade, Jay McCoy, Kar Muthumani, David B. Weiner, Laurent M. Humeau & Kate E. Broderick. (2019) Integration of needle-free jet injection with advanced electroporation delivery enhances the magnitude, kinetics, and persistence of engineered DNA vaccine induced immune responses. Vaccine 37:29, pages 3832-3839.
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Rianne N. Esquivel, Ami Patel, Sagar B. Kudchodkar, Daniel H. Park, Karin Stettler, Martina Beltramello, Jeffrey W. Allen, Janess Mendoza, Stephanie Ramos, Hyeree Choi, Piyush Borole, Kanika Asija, Mamadou Bah, Shareef Shaheen, Jing Chen, Jian Yan, Amy C. Durham, Trevor R.F. Smith, Kate Broderick, Ghiabe Guibinga, Kar Muthumani, Davide Corti, Laurent Humeau & David B. Weiner. (2019) In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus. Molecular Therapy 27:5, pages 974-985.
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Nushin Hosano & Hamid Hosano. (2018) Prospects and challenges of physical manipulation of the cell membrane. Physics of Life Reviews 26-27, pages 43-46.
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Ami Patel, Daniel H. Park, Carl W. Davis, Trevor R.F. Smith, Anders Leung, Kevin Tierney, Aubrey Bryan, Edgar Davidson, Xiaoying Yu, Trina Racine, Charles Reed, Marguerite E. Gorman, Megan C. Wise, Sarah T.C. Elliott, Rianne Esquivel, Jian Yan, Jing Chen, Kar Muthumani, Benjamin J. Doranz, Erica Ollmann Saphire, James E. Crowe, Kate E. Broderick, Gary P. Kobinger, Shihua He, Xiangguo Qiu, Darwyn Kobasa, Laurent Humeau, Niranjan Y. Sardesai, Rafi Ahmed & David B. Weiner. (2018) In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Reports 25:7, pages 1982-1993.e4.
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