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The early bactericidal activity of antituberculosis drugs

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Neesha Rockwood, Elsa du Bruyn, Thomas Morris & Robert J Wilkinson. (2016) Assessment of treatment response in tuberculosis. Expert Review of Respiratory Medicine 10:6, pages 643-654.
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Rami Ayoun Alsoud, Robin J. Svensson, Elin M. Svensson, Stephen H. Gillespie, Martin J. Boeree, Andreas H. Diacon, Rodney Dawson, Rob E. Aarnoutse & Ulrika S. H. Simonsson. (2023) Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development. Frontiers in Pharmacology 14.
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Julian S. Peters, Amanda McIvor, Andrea O. Papadopoulos, Tshepiso Masangana, Bhavna G. Gordhan, Ziyaad Waja, Kennedy Otwombe, Matebogo Letutu, Mireille Kamariza, Timothy R. Sterling, Carolyn R. Bertozzi, Neil A. Martinson & Bavesh D. Kana. (2023) Differentially culturable tubercle bacteria as a measure of tuberculosis treatment response. Frontiers in Cellular and Infection Microbiology 12.
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Jan-Willem C. Alffenaar, Jurriaan E. M. de Steenwinkel, Andreas H. Diacon, Ulrika S. H. Simonsson, Shashikant Srivastava & Sebastian G. Wicha. (2022) Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies. Frontiers in Pharmacology 13.
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Saurabh Mishra & Kohta Saito. (2022) Clinically encountered growth phenotypes of tuberculosis-causing bacilli and their in vitro study: A review. Frontiers in Cellular and Infection Microbiology 12.
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Jan Heyckendorf, Sophia B. Georghiou, Nicole Frahm, Norbert Heinrich, Irina Kontsevaya, Maja Reimann, David Holtzman, Marjorie Imperial, Daniela M. Cirillo, Stephen H. Gillespie & Morten Ruhwald. (2022) Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies. Clinical Microbiology Reviews 35:3.
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Guilherme F. S. Fernandes, Andrew M. Thompson, Daniele Castagnolo, William A. Denny & Jean L. Dos Santos. (2022) Tuberculosis Drug Discovery: Challenges and New Horizons. Journal of Medicinal Chemistry 65:11, pages 7489-7531.
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Jahan Saeed Mallick, Parvati Nair, Elizabeth Tabitha Abbew, Armand Van Deun & Tom Decroo. (2022) Acquired bedaquiline resistance during the treatment of drug-resistant tuberculosis: a systematic review. JAC-Antimicrobial Resistance 4:2.
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Yingda L. Xie, Veronique R. de Jager, Ray Y. Chen, Lori E. Dodd, Praveen Paripati, Laura E. Via, Dean Follmann, Jing WangKeith LumbardSaher LahouarStephanus T. MalherbeJenna AndrewsXiang YuLisa C. Goldfeder, Ying Cai, Kriti Arora, Andre G. Loxton, Naadira VankerMichael Duvenhage, Jill Winter, Taeksun Song, Gerhard WalzlAndreas H. Diacon & Clifton E. BarryIIIIII. (2021) Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis. Science Translational Medicine 13:579.
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Federico Appetecchia, Sara Consalvi, Cristina Scarpecci, Mariangela Biava & Giovanna Poce. (2020) SAR Analysis of Small Molecules Interfering with Energy-Metabolism in Mycobacterium tuberculosis. Pharmaceuticals 13:9, pages 227.
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Andreas Diacon, Sachiko Miyahara, Rodney Dawson, Xin Sun, Evelyn Hogg, Kathleen Donahue, Michael Urbanowski, Veronique De Jager, Courtney V Fletcher, Richard Hafner, Susan Swindells & William Bishai. (2020) Assessing whether isoniazid is essential during the first 14 days of tuberculosis therapy: a phase 2a, open-label, randomised controlled trial. The Lancet Microbe 1:2, pages e84-e92.
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Anthony Lee, Yingda Linda Xie, Clifton E Barry & Ray Y Chen. (2020) Current and future treatments for tuberculosis. BMJ, pages m216.
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Michael A. Lyons. (2019) Modeling and Simulation of Pretomanid Pharmacodynamics in Pulmonary Tuberculosis Patients. Antimicrobial Agents and Chemotherapy 63:12.
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Beth Shoshana Zha & Payam Nahid. (2019) Treatment of Drug-Susceptible Tuberculosis. Clinics in Chest Medicine 40:4, pages 763-774.
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Antonia Morita I. Saktiawati, Marcel Harkema, Althaf Setyawan, Yanri W. Subronto, Sumardi, Ymkje Stienstra, Rob E. Aarnoutse, Cecile Magis-Escurra, Jos G. W. Kosterink, Tjip S. van der Werf, Jan-Willem C. Alffenaar & Marieke G. G. Sturkenboom. (2019) Optimal Sampling Strategies for Therapeutic Drug Monitoring of First-Line Tuberculosis Drugs in Patients with Tuberculosis. Clinical Pharmacokinetics 58:11, pages 1445-1454.
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Na Wang, Yongyan Zou, Kang Yang & Jinguo Wang. (2019) The sustained-release effect of triple anti-tuberculosis drugs carried by calcium sulfate/poly-amino acid compound materials in bone tuberculosis lesion. IOP Conference Series: Materials Science and Engineering 587:1, pages 012003.
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Gail B. Cross, Benjamin C-M Yeo, Paul Edward Hutchinson, Mark C. Tan, Rupangi Verma, Qingshu Lu & Nicholas I. Paton. (2019) Impact of selective immune-cell depletion on growth of Mycobacterium tuberculosis (Mtb) in a whole-blood bactericidal activity (WBA) assay. PLOS ONE 14:5, pages e0216616.
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Jan-Willem C. Alffenaar, Onno W. Akkerman & Graham Bothamley. 2018. Tuberculosis. Tuberculosis 308 325 .
Bai-Yu Lee, Daniel L. Clemens, Aleidy Silva, Barbara Jane Dillon, Saša Masleša-Galić, Susana Nava, Chih-Ming Ho & Marcus A. Horwitz. (2018) Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility. PLOS ONE 13:11, pages e0207469.
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M Daben J Libardo, Helena IM Boshoff & Clifton E BarryIIIIII. (2018) The present state of the tuberculosis drug development pipeline. Current Opinion in Pharmacology 42, pages 81-94.
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Tianao Yuan & Nicole S. Sampson. (2018) Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews 118:4, pages 1887-1916.
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Robin J. Svensson, Stephen H. Gillespie & Ulrika S. H. Simonsson. (2017) Improved power for TB Phase IIa trials using a model-based pharmacokinetic–pharmacodynamic approach compared with commonly used analysis methods. Journal of Antimicrobial Chemotherapy 72:8, pages 2311-2319.
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Alvaro Proaño, Marjory A. Bravard, José W. López, Gwenyth O. Lee, David Bui, Sumona Datta, Germán Comina, Mirko Zimic, Jorge Coronel, Luz Caviedes, José L. Cabrera, Antonio Salas, Eduardo Ticona, Nancy M. Vu, Daniela E. Kirwan, Maria-Cristina I. Loader, Jon S. Friedland, David A. J. Moore, Carlton A. Evans, Brian H. Tracey & Robert H. Gilman. (2017) Dynamics of Cough Frequency in Adults Undergoing Treatment for Pulmonary Tuberculosis. Clinical Infectious Diseases 64:9, pages 1174-1181.
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Véronique Dartois, Kohta Saito, Thulasi Warrier & Carl Nathan. (2016) New Evidence for the Complexity of the Population Structure of Mycobacterium tuberculosis Increases the Diagnostic and Biologic Challenges . American Journal of Respiratory and Critical Care Medicine 194:12, pages 1448-1451.
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Thomas Pouplin, Nguyen Duc Bang, Pham Van Toi, Pham Nguyen Phuong, Nguyen Huy Dung, Tran Ngoc Duong, Maxine Caws, Guy E. Thwaites, Joel Tarning & Jeremy N. Day. (2016) Naïve-pooled pharmacokinetic analysis of pyrazinamide, isoniazid and rifampicin in plasma and cerebrospinal fluid of Vietnamese children with tuberculous meningitis. BMC Infectious Diseases 16:1.
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Payam Nahid, Susan E. Dorman, Narges Alipanah, Pennan M. Barry, Jan L. Brozek, Adithya Cattamanchi, Lelia H. Chaisson, Richard E. Chaisson, Charles L. Daley, Malgosia Grzemska, Julie M. Higashi, Christine S. Ho, Philip C. Hopewell, Salmaan A. Keshavjee, Christian Lienhardt, Richard Menzies, Cynthia Merrifield, Masahiro Narita, Rick O'Brien, Charles A. Peloquin, Ann Raftery, Jussi Saukkonen, H. Simon Schaaf, Giovanni Sotgiu, Jeffrey R. Starke, Giovanni Battista Migliori & Andrew Vernon. (2016) Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis. Clinical Infectious Diseases 63:7, pages e147-e195.
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Xavier A. Kayigire, Sven O. Friedrich, Lize van der Merwe, Peter R. Donald & Andreas H. Diacon. (2015) Simultaneous staining of sputum smears for acid-fast and lipid-containing Myobacterium tuberculosis can enhance the clinical evaluation of antituberculosis treatments. Tuberculosis 95:6, pages 770-779.
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Sam Ogwang, Caryn E. Good, Brenda Okware, Mary Nsereko, Michael R. Jacobs, W. Henry Boom & Charles M. Bark. (2015) Sulfamethoxazole Susceptibility of Mycobacterium tuberculosis Isolates from HIV-Infected Ugandan Adults with Tuberculosis Taking Trimethoprim-Sulfamethoxazole Prophylaxis. Antimicrobial Agents and Chemotherapy 59:9, pages 5844-5846.
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S. Thee, A.J. Garcia-Prats, P.R. Donald, A.C. Hesseling & H.S. Schaaf. (2015) Fluoroquinolones for the treatment of tuberculosis in children. Tuberculosis 95:3, pages 229-245.
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Ioana Diana Olaru, Florian von Groote-Bidlingmaier, Jan Heyckendorf, Wing Wai Yew, Christoph Lange & Kwok Chiu Chang. (2015) Novel drugs against tuberculosis: a clinician's perspective. European Respiratory Journal 45:4, pages 1119-1131.
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