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Amyloid-β as a biomarker for Alzheimer’s disease: quantification methods in body fluids

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Natalia V. Zakharova, Anna E. Bugrova, Alexey S. Kononikhin, Maria I. Indeykina, Igor A. Popov & Eugene N. Nikolaev. (2018) Mass spectrometry analysis of the diversity of Aβ peptides: difficulties and future perspectives for AD biomarker discovery. Expert Review of Proteomics 15:10, pages 773-775.
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Stephanie L. Baringer, Avraham S. Lukacher, Kondaiah Palsa, Hyosung Kim, Ethan S. Lippmann, Vladimir S. Spiegelman, Ian A. Simpson & James R. Connor. (2023) Amyloid‐β exposed astrocytes induce iron transport from endothelial cells at the blood–brain barrier by altering the ratio of apo‐ and holo‐transferrin. Journal of Neurochemistry.
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Haiwei Ji, Xiaoxia Kang, Xiaoxiao Yang, Huanhuan Chen, lvyang Zhu, Tianzhi Mao, Yue He, Jinxia Liu, Qi Wang, Xiaobo Zhou, Guo Li, Mingmin Wu, Hui Cong, Li Wu & Yuling Qin. (2023) Functionalized graphene-based electrochemical array sensors for the identification of distinct conformational states of Amyloid Beta in Alzheimer's disease. Biosensors and Bioelectronics 222, pages 114927.
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Simona Itri, Danila del Giudice, Martina Mugnano, Volodymyr Tkachenko, Sanna Uusitalo, Annukka Kokkonen, Inka Päkkilä, Heidi Ottevaere, Yunfeng Nie, Emanuela Mazzon, Agnese Gugliandolo, Pietro Ferraro & Simonetta Grilli. (2022) A pin-based pyro-electrohydrodynamic jet sensor for tuning the accumulation of biomolecules down to sub-picogram level detection. Sensing and Bio-Sensing Research 38, pages 100536.
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Natalia V. Zakharova, Anna E. Bugrova, Maria I. Indeykina, Yana B. Fedorova, Igor V. Kolykhalov, Svetlana I. Gavrilova, Evgeny N. Nikolaev & Alexey S. Kononikhin. (2022) Proteomic Markers and Early Prediction of Alzheimer’s Disease. Biochemistry (Moscow) 87:8, pages 762-776.
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Alexey S. Kononikhin, Natalia V. Zakharova, Savva D. Semenov, Anna E. Bugrova, Alexander G. Brzhozovskiy, Maria I. Indeykina, Yana B. Fedorova, Igor V. Kolykhalov, Polina A. Strelnikova, Anna Yu. Ikonnikova, Dmitry A. Gryadunov, Svetlana I. Gavrilova & Evgeny N. Nikolaev. (2022) Prognosis of Alzheimer’s Disease Using Quantitative Mass Spectrometry of Human Blood Plasma Proteins and Machine Learning. International Journal of Molecular Sciences 23:14, pages 7907.
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Julia Doroszkiewicz, Magdalena Groblewska & Barbara Mroczko. (2022) Molecular Biomarkers and Their Implications for the Early Diagnosis of Selected Neurodegenerative Diseases. International Journal of Molecular Sciences 23:9, pages 4610.
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Natalia V. Zakharova, Alexey S. Kononikhin, Maria I. Indeykina, Anna E. Bugrova, Polina Strelnikova, Stanislav Pekov, Sergey A. Kozin, Igor A. Popov, Vladimir Mitkevich, Alexander A. Makarov & Evgeny N. Nikolaev. (2022) Mass spectrometric studies of the variety of beta‐amyloid proteoforms in Alzheimer's disease. Mass Spectrometry Reviews.
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Hsiao-Fen Han, Hung-Chi Yen, Hsiu-Chuan Wu, Hsin-Yuan Tan, Wei Xu, Hang-Shiang Jiang, Ping-Jui Tsai, Kun Qian, Yi-Chun Wu & Chia-Chun Chen. (2021) Ultrasensitive Detection of Alzheimer’s Amyloids on a Plasmonic-Gold Platform. ACS Applied Materials & Interfaces 13:48, pages 57036-57042.
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Cristina M. Pedrero-Prieto, Sonia García-Carpintero, Javier Frontiñán-Rubio, Emilio Llanos-González, Cristina Aguilera García, Francisco J. Alcaín, Iris Lindberg, Mario Durán-Prado, Juan R. Peinado & Yoana Rabanal-Ruiz. (2020) A comprehensive systematic review of CSF proteins and peptides that define Alzheimer’s disease. Clinical Proteomics 17:1.
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Chengyi Yuan, Weiping Duan, Jian Luo, Yuwang Han & Xiaohui Wang. (2020) Human serum albumin-mediated recognition of soluble amyloid-β peptides using a time-resolved luminescent probe in plasma. Chemical Communications 56:44, pages 5945-5948.
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Wei-Hsuan Sung, Jung-Tung Hung, Yu-Jen Lu & Chao-Min Cheng. (2020) Paper-Based Detection Device for Alzheimer’s Disease—Detecting β-amyloid Peptides (1–42) in Human Plasma. Diagnostics 10:5, pages 272.
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Muhammad Naveed, Shamsa Mubeen, Abeer Khan, Sehrish Ibrahim & Bisma Meer. (2019) Plasma Biomarkers: Potent Screeners of Alzheimer’s Disease. American Journal of Alzheimer's Disease & Other Dementias® 34:5, pages 290-301.
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Stanislav I. Pekov, Daniil G. Ivanov, Anna E. Bugrova, Maria I. Indeykina, Natalia V. Zakharova, Igor A. Popov, Alexey S. Kononikhin, Sergey A. Kozin, Alexander A. Makarov & Evgeny N. Nikolaev. (2019) Evaluation of MALDI-TOF/TOF Mass Spectrometry Approach for Quantitative Determination of Aspartate Residue Isomerization in the Amyloid-β Peptide. Journal of the American Society for Mass Spectrometry 30:7, pages 1325-1329.
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Fred Hudd, Anna Shiel, Matthew Harris, Paul Bowdler, Bryony McCann, Demitra Tsivos, Alfie Wearn, Michael Knight, Risto Kauppinen, Elizabeth Coulthard, Paul White & Myra Elizabeth Conway. (2019) Novel Blood Biomarkers that Correlate with Cognitive Performance and Hippocampal Volumetry: Potential for Early Diagnosis of Alzheimer’s Disease. Journal of Alzheimer's Disease 67:3, pages 931-947.
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Keping Chen, Tianli Gao, Zhimao Bai & Zuanning Yuan. (2018) Circulating APP, NCAM and Aβ serve as biomarkers for Alzheimer’s disease. Brain Research 1699, pages 117-120.
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Wai‐Ming Yau & Robert Tycko. (2018) Depletion of amyloid‐β peptides from solution by sequestration within fibril‐seeded hydrogels. Protein Science 27:7, pages 1218-1230.
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Forough Ghasemi, M. Reza Hormozi-Nezhad & Morteza Mahmoudi. (2018) Label-free detection of β-amyloid peptides (Aβ40 and Aβ42): a colorimetric sensor array for plasma monitoring of Alzheimer's disease. Nanoscale 10:14, pages 6361-6368.
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Izabella J. Jahn, Andreea I. Radu, Karina Weber, Dana Cialla-May & Juergen Popp. 2018. Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis. Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis 1 66 .
Jung-Lung Hsu, Wei-Ju Lee, Yi-Chu Liao, Jiing-Feng Lirng, Shuu-Jiun Wang & Jong-Ling Fuh. (2017) Plasma biomarkers are associated with agitation and regional brain atrophy in Alzheimer’s disease. Scientific Reports 7:1.
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Zhao Huang, Linguang Ma, Canhua Huang, Qifu Li & Edouard C. Nice. (2016) Proteomic profiling of human plasma for cancer biomarker discovery. PROTEOMICS 17:6.
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Saara Mikkonen, Johan Jacksén, Johan Roeraade, Wolfgang Thormann & Åsa Emmer. (2016) Microfluidic Isoelectric Focusing of Amyloid Beta Peptides Followed by Micropillar-Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry. Analytical Chemistry 88:20, pages 10044-10051.
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Akin Sevinc, Dilek Yonar & Feride Severcan. (2015) Investigation of neurodegenerative diseases from body fluid samples using Fourier transform infrared spectroscopy. Biomedical Spectroscopy and Imaging 4:4, pages 341-357.
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Simona Itri, Danila del Giudice, Martina Mugnano, Volodymyr Tkachenko, Sanna Uusitalo, Annukka Kokkonen, Inka Päkkilä, Heidi Ottevaere, Yunfeng Nie, Emanuela Mazzon, Agnese Gugliandolo, Pietro Ferraro & Simonetta Grilli. (2022) A Pin-Based Pyro-Electrohydrodynamic Jet Sensor for Tuning the Accumulation of Biomolecules Down to Sub-Picogram Level Detection. SSRN Electronic Journal.
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