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Review

Biomedical applications of polyhydroxyalkanoates, an overview of animal testing and in vivo responses

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Pages 853-868 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Syed Mohammad Daniel Syed Mohamed, Nor Faezah Ansari, Nurhezreen Md Iqbal & Siti Nor Syairah Anis. (2022) Polyhydroxyalkanoates (PHA)-based responsive polymers. International Journal of Polymeric Materials and Polymeric Biomaterials 71:17, pages 1283-1302.
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Ya-Wen Zhang, Ling-Lan Tu, Zhan Tang, Qiao Wang, Gao-Li Zheng & Li-Na Yin. (2021) pH-sensitive chitosan-deoxycholic acid/alginate nanoparticles for oral insulin delivery. Pharmaceutical Development and Technology 26:9, pages 943-952.
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Mădălina Elena Grigore, Ramona Marina Grigorescu, Lorena Iancu, Rodica-Mariana Ion, Cătălin Zaharia & Elena Ramona Andrei. (2019) Methods of synthesis, properties and biomedical applications of polyhydroxyalkanoates: a review. Journal of Biomaterials Science, Polymer Edition 30:9, pages 695-712.
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Sasikala Sadasivam, Santhosh Sigamani, Hemalatha Venkatachalam & Dhandapani Ramamurthy. (2018) A New Method for the Production of Polyhydroxyalkanoates by Bacillus sp. and Detect the Presence of PHA Synthase. Smart Science 6:2, pages 105-116.
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Ganesan Sathiyanarayanan, Ganesan Saibaba, George Seghal Kiran, Yung-Hun Yang & Joseph Selvin. (2017) Marine sponge-associated bacteria as a potential source for polyhydroxyalkanoates. Critical Reviews in Microbiology 43:3, pages 294-312.
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GamalR. Saad, MoatazA. Elsawy & MaherZ. Elsabee. (2012) Preparation, Characterization and Antimicrobial Activity of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)-g-Poly(N-vinylpyrrolidone) Copolymers. Polymer-Plastics Technology and Engineering 51:11, pages 1113-1121.
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Yu-Cui Xiong, Yong-Chao Yao, Xiao-Yong Zhan & Guo-Qiang Chen. (2010) Application of Polyhydroxyalkanoates Nanoparticles as Intracellular Sustained Drug-Release Vectors. Journal of Biomaterials Science, Polymer Edition 21:1, pages 127-140.
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Qiong Wu, Yang Wang & Guo-Qiang Chen. (2009) Medical Application of Microbial Biopolyesters Polyhydroxyalkanoates. Artificial Cells, Blood Substitutes, and Biotechnology 37:1, pages 1-12.
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Qian Liu & Guo-Qiang Chen. (2008) In vitro biocompatibility and degradation of terpolyester 3HB-co-4HB-co-3HHx, consisting of 3-hydroxybutyrate, 4-hydroxybutyrate and 3-hydroxyhexanoate. Journal of Biomaterials Science, Polymer Edition 19:11, pages 1521-1533.
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Maria Rosaria Caputo, Mercedes Fernández, Robert Aguirresarobe, Adriana Kovalcik, Haritz Sardon, María Virginia Candal & Alejandro J. Müller. (2023) Influence of FFF Process Conditions on the Thermal, Mechanical, and Rheological Properties of Poly(hydroxybutyrate-co-hydroxy Hexanoate). Polymers 15:8, pages 1817.
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