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Chronic inflammation and cancer: emerging roles of triggering receptors expressed on myeloid cells

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Barbara Azzimonti, Luca Raimondo, Diletta Francesca Squarzanti, Tiziana Rosso, Paola Zanetta, Paolo Aluffi Valletti, Luigi Chiusa, Laura Masini, Giancarlo Pecorari, Mario Airoldi, Marco Krengli, Mirella Giovarelli & Guido Valente. (2021) Macrophages expressing TREM-1 are involved in the progression of HPV16-related oropharyngeal squamous cell carcinoma. Annals of Medicine 53:1, pages 541-550.
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Raffaella Fontana, Laura Raccosta, Lucrezia Rovati, Knut R. Steffensen, Aida Paniccia, Tomas Jakobsson, Giulio Melloni, Alessandro Bandiera, Giorgia Mangili, Alice Bergamini, Daniela Maggioni, Claudio Doglioni, Roberto Crocchiolo, Marina Cella, Michela Mattioli, Cristina Battaglia, Marco Colonna & Vincenzo Russo. (2019) Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors. OncoImmunology 8:3.
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Courtney P. Rudick, Takanari Miyamoto, Melissa S. Lang & Devendra K. Agrawal. (2017) Triggering receptor expressed on myeloid cells in the pathogenesis of periodontitis: potential novel treatment strategies. Expert Review of Clinical Immunology 13:12, pages 1189-1197.
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Ashwin Ajith, Kenza Mamouni, Daniel D. Horuzsko, Abu Musa, Amiran K. Dzutsev, Jennifer R. Fang, Ahmed Chadli, Xingguo Zhu, Iryna Lebedyeva, Giorgio Trinchieri & Anatolij Horuzsko. (2023) Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance. Journal of Clinical Investigation 133:21.
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Vladislava Juric, Erin MayesMikhail BinnewiesTian LeePamela CanadayJoshua L. PollackJoshua Rudolph, Xiaoyan DuVictoria M. LiuSubhadra DashRachael PalmerNadine S. JahchanÅsa Johanna RamothSergio LacayoShilpa MankikarManith NorngChris Brassell, Aritra PalChristopher ChanErick Lu, Venkataraman Sriram, Michel Streuli, Matthew F. Krummel, Kevin P. Baker & Linda Liang. (2023) TREM1 activation of myeloid cells promotes antitumor immunity. Science Translational Medicine 15:711.
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Dandan Zhu, Min Huang, Pei Shen, Bei Zhang, Guo Chen, Jinling Chen, Lian Duan & Yinong Duan. (2023) TREM2 expression promotes liver and peritoneal M2 macrophage polarization in mice infected with Schistosoma japonicum . Journal of Cellular and Molecular Medicine 27:15, pages 2261-2269.
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Marie Muller, Vincent Haghnejad, Anthony Lopez, Angelica Tiotiu, Stéphane Renaud, Marc Derive & Jean-Pierre Bronowicki. (2022) Triggering Receptors Expressed on Myeloid Cells 1 : Our New Partner in Human Oncology?. Frontiers in Oncology 12.
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Milena Hornburg, Mélanie Desbois, Shan Lu, Yinghui Guan, Amy A. Lo, Susan Kaufman, Ashley Elrod, Alina Lotstein, Teresa M. DesRochers, Jose L. Munoz-Rodriguez, Xingwei Wang, Jennifer Giltnane, Oleg Mayba, Shannon J. Turley, Richard Bourgon, Anneleen Daemen & Yulei Wang. (2021) Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer. Cancer Cell 39:7, pages 928-944.e6.
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Xin Cheng, Xiaowei Wang, Kechao Nie, Lin Cheng, Zheyu Zhang, Yang Hu & Weijun Peng. (2021) Systematic Pan-Cancer Analysis Identifies TREM2 as an Immunological and Prognostic Biomarker. Frontiers in Immunology 12.
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Muthu K. Shanmugam, Arunasalam Dharmarajan, Sudha Warrier, Anupam Bishayee, Alan Prem Kumar, Gautam Sethi & Kwang Seok Ahn. 2021. Apoptosis in Health and Disease - Part A. Apoptosis in Health and Disease - Part A 149 191 .
Alexander B. Sigalov. (2020) SCHOOL of nature: ligand-independent immunomodulatory peptides. Drug Discovery Today 25:8, pages 1298-1306.
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Federica Raggi & Maria Bosco. (2020) Targeting Mononuclear Phagocyte Receptors in Cancer Immunotherapy: New Perspectives of the Triggering Receptor Expressed on Myeloid Cells (TREM-1). Cancers 12:5, pages 1337.
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Alexander B. Sigalov. (2020) Commentary: Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor Targeted to Endothelium Decreases Cell Activation. Frontiers in Immunology 11.
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Xiaoming Huang, Jue Wang, Wanjun Lin, Na Zhang, Jingjing Du, Ze Long, You Yang, Bowen Zheng, Fangfang Zhong, Qibiao Wu & Wenzhe Ma. (2020) Kanglaite injection plus platinum-based chemotherapy for stage III/IV non-small cell lung cancer: A meta-analysis of 27 RCTs. Phytomedicine 67, pages 153154.
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Tianze Zhang, Yongchao Li, Ruidong Zhu, Pengcheng Song, Youlei Wei, Tian Liang & Guangquan Xu. (2019) Transcription Factor p53 Suppresses Tumor Growth by Prompting Pyroptosis in Non-Small-Cell Lung Cancer. Oxidative Medicine and Cellular Longevity 2019, pages 1-9.
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Jing Wang, Danyang Li, Huaixing Cang & Bo Guo. (2019) Crosstalk between cancer and immune cells: Role of tumor‐associated macrophages in the tumor microenvironment. Cancer Medicine 8:10, pages 4709-4721.
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Qinchuan Wu, Wuhua Zhou, Shengyong Yin, Yuan Zhou, Tianchi Chen, Junjie Qian, Rong Su, Liangjie Hong, Haohao Lu, Feng Zhang, Haiyang Xie, Lin Zhou & Shusen Zheng. (2019) Blocking Triggering Receptor Expressed on Myeloid Cells‐1‐Positive Tumor‐Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti‐Programmed Cell Death Ligand 1 Resistance in Liver Cancer. Hepatology 70:1, pages 198-214.
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Sankar Baruah, Shubha Murthy, Kathy Keck, Isabel Galvan, Allan Prichard, Lee-Ann H Allen, Mary Farrelly & Julia Klesney-Tait. (2019) TREM-1 regulates neutrophil chemotaxis by promoting NOX-dependent superoxide production. Journal of Leukocyte Biology 105:6, pages 1195-1207.
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Muthu K. Shanmugam, Frank Arfuso, Judy C. Sng, Anupam Bishayee, Alan Prem Kumar & Gautam Sethi. 2019. Epigenetics of Cancer Prevention. Epigenetics of Cancer Prevention 107 128 .
Kouassi Kouassi, Palanikumar Gunasekar, Devendra Agrawal & Gopal Jadhav. (2018) TREM-1; Is It a Pivotal Target for Cardiovascular Diseases?. Journal of Cardiovascular Development and Disease 5:3, pages 45.
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Thomas Efferth & Manfred Volm. (2017) Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers. Archives of Toxicology 91:7, pages 2515-2538.
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Virginia Camacho, Victoria McClearn, Sweta Patel & Robert S. Welner. (2017) Regulation of normal and leukemic stem cells through cytokine signaling and the microenvironment. International Journal of Hematology 105:5, pages 566-577.
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Yue Yu, Hao Li, Yucai Yang, Yitao Ding, Zhaoxia Wang & Genxi Li. (2016) Evaluating Tumor-Associated Activity of Extracellular Sulfatase by Analyzing Naturally Occurring Substrate in Tumor Microenvironment of Hepatocellular Carcinoma. Analytical Chemistry 88:24, pages 12287-12293.
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Austin Huy Nguyen, Carleigh Koenck, Shannon K. Quirk, Victoria M. Lim, Mario V. Mitkov, Ryan M. Trowbridge, William J. HunterIIIIII & Devendra K. Agrawal. (2015) Triggering Receptor Expressed on Myeloid Cells in Cutaneous Melanoma. Clinical and Translational Science 8:5, pages 441-444.
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