Advanced search
Publication Cover
Expert Review of Anti-infective Therapy Volume 8, 2010 - Issue 9
Submit an article Journal homepage
491
Views
51
CrossRef citations to date
0
Altmetric
Review

Emergence and clinical insights into the pathology of Chikungunya virus infection

Marie Christine Jaffar-Bandjee Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Duksha Ramful Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Bernard Alex Gauzere Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Jean Jacques Hoarau Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Pascale Krejbich-Trotot Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Stephanie Robin Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Anne Ribera Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
,
Jimmy Selambarom Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France; Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France
&
Philippe Gasque Groupe de recherche immunopathologie et maladies infectieuses (GRI), Université de la Réunion et CHR Félix Guyon, Plateau technique du CYROI, 2 rue Maxime Rivière, 97470 Sainte-Clotilde, Reunion, France;[email protected]; [email protected]
 show all
Pages 987-996 | Published online: 10 Jan 2014

Citations (51)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Anil K. Jasti, Carlo Selmi, Juan C. Sarmiento-Monroy, Daniel A. Vega, Juan-Manuel Anaya & M. Eric Gershwin. (2016) Guillain-Barré syndrome: causes, immunopathogenic mechanisms and treatment. Expert Review of Clinical Immunology 12:11, pages 1175-1189.
Read now

Articles from other publishers (50)

Koen Bartholomeeusen, Matthieu Daniel, Desiree A. LaBeaud, Philippe Gasque, Rosanna W. Peeling, Kathryn E. Stephenson, Lisa F. P. Ng & Kevin K. Ariën. (2023) Chikungunya fever. Nature Reviews Disease Primers 9:1.
Crossref
Larissa E. C. Constant, Bia F. Rajsfus, Pedro H. Carneiro, Tháyna Sisnande, Ronaldo Mohana-Borges & Diego Allonso. (2021) Overview on Chikungunya Virus Infection: From Epidemiology to State-of-the-Art Experimental Models. Frontiers in Microbiology 12.
Crossref
Muhammed Muhsin Varikkodan, Chun-Chung Chen & Tzong-Yuan Wu. (2021) Recombinant Baculovirus: A Flexible Drug Screening Platform for Chikungunya Virus. International Journal of Molecular Sciences 22:15, pages 7891.
Crossref
Anil Verma, Kaustuv Nayak, Anmol Chandele, Mohit Singla, Vinod H. Ratageri, Rakesh Lodha, Sushil Kumar Kabra, Kaja Murali-Krishna & Pratima Ray. (2021) Chikungunya-specific IgG and neutralizing antibody responses in natural infection of Chikungunya virus in children from India. Archives of Virology 166:7, pages 1913-1920.
Crossref
Javid Sadri Nahand, Layla Shojaie, Seyed Amirreza Akhlagh, Mohammad Saeid Ebrahimi, Hamid Reza Mirzaei, Hossein Bannazadeh Baghi, Maryam Mahjoubin-Tehran, Nima Rezaei, Michael R. Hamblin, Vida Tajiknia, Neda Rahimian & Hamed Mirzaei. (2021) Cell death pathways and viruses: Role of microRNAs. Molecular Therapy - Nucleic Acids 24, pages 487-511.
Crossref
Karol Suchowiecki, St. Patrick Reid, Gary L. Simon, Gary S. Firestein & Aileen Chang. (2021) Persistent Joint Pain Following Arthropod Virus Infections. Current Rheumatology Reports 23:4.
Crossref
Natalie A. Prow, Thiago D. C. Hirata, Bing Tang, Thibaut Larcher, Pamela Mukhopadhyay, Tiago Lubiana Alves, Thuy T. Le, Joy Gardner, Yee Suan Poo, Eri Nakayama, Viviana P. Lutzky, Helder I. Nakaya & Andreas Suhrbier. (2019) Exacerbation of Chikungunya Virus Rheumatic Immunopathology by a High Fiber Diet and Butyrate. Frontiers in Immunology 10.
Crossref
Andreas Suhrbier. (2019) Rheumatic manifestations of chikungunya: emerging concepts and interventions. Nature Reviews Rheumatology 15:10, pages 597-611.
Crossref
Alessandra Soares-Schanoski, Natália Baptista Cruz, Luíza Antunes de Castro-Jorge, Renan Villanova Homem de Carvalho, Cliomar Alves dos Santos, Nancy da Rós, Úrsula Oliveira, Danuza Duarte Costa, Cecília Luíza Simões dos Santos, Marielton dos Passos Cunha, Maria Leonor Sarno Oliveira, Juliana Cardoso Alves, Regina Adalva de Lucena Couto Océa, Danielle Rodrigues Ribeiro, André Nicolau Aquime Gonçalves, Patricia Gonzalez-Dias, Andreas Suhrbier, Paolo Marinho de Andrade Zanotto, Inácio Junqueira de Azevedo, Dario S. Zamboni, Roque Pacheco Almeida, Paulo Lee Ho, Jorge Kalil, Milton Yutaka Nishiyama & Helder I. Nakaya. (2019) Systems analysis of subjects acutely infected with the Chikungunya virus. PLOS Pathogens 15:6, pages e1007880.
Crossref
Christopher H. Hsu, Fabiola Cruz-Lopez, Danulka Vargas Torres, Janice Perez-Padilla, Olga D. Lorenzi, Aidsa Rivera, J. Erin Staples, Esteban Lugo, Jorge Munoz-Jordan, Marc Fischer, Carlos Garcia Gubern, Brenda Rivera Garcia, Luisa Alvarado & Tyler M. Sharp. (2019) Risk factors for hospitalization of patients with chikungunya virus infection at sentinel hospitals in Puerto Rico. PLOS Neglected Tropical Diseases 13:1, pages e0007084.
Crossref
Ivan Akhrymuk, Ilya Frolov & Elena I. Frolova. (2018) Sindbis Virus Infection Causes Cell Death by nsP2-Induced Transcriptional Shutoff or by nsP3-Dependent Translational Shutoff. Journal of Virology 92:23.
Crossref
Yhojan Rodríguez, Manuel Rojas, Yovana Pacheco, Yeny Acosta-Ampudia, Carolina Ramírez-Santana, Diana M Monsalve, M Eric Gershwin & Juan-Manuel Anaya. (2018) Guillain–Barré syndrome, transverse myelitis and infectious diseases. Cellular & Molecular Immunology 15:6, pages 547-562.
Crossref
Tran Minh Quan, Huynh Thi Phuong, Nguyen Ha Thao Vy, Nguyen Thi Le Thanh, Nguyen Thi Nam Lien, Tran Thi Kim Hong, Pham Ngoc Dung, Nguyen Van Vinh Chau, Maciej F. Boni & Hannah E. Clapham. (2018) Evidence of previous but not current transmission of chikungunya virus in southern and central Vietnam: Results from a systematic review and a seroprevalence study in four locations. PLOS Neglected Tropical Diseases 12:2, pages e0006246.
Crossref
Roberto Mogami, João Luiz Pereira Vaz, Yêdda de Fátima Barcelos Chagas, Mirhelen Mendes de Abreu, Rodrigo Sperling Torezani, André de Almeida Vieira, Eduardo Alvarenga Junqueira Filho, Yasmin Baptista Barbosa, Antonio Carlos Pires Carvalho & Agnaldo José Lopes. (2018) Ultrasonography of Hands and Wrists in the Diagnosis of Complications of Chikungunya Fever. Journal of Ultrasound in Medicine 37:2, pages 511-520.
Crossref
Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque & Marie-Christine Jaffar-Bandjee. (2017) Improved detection of genus-specific Alphavirus using a generic TaqMan® assay. BMC Microbiology 17:1.
Crossref
Sarika AmdekarDeepti ParasharKalichamy Alagarasu. (2017) Chikungunya Virus-Induced Arthritis: Role of Host and Viral Factors in the Pathogenesis. Viral Immunology 30:10, pages 691-702.
Crossref
Szu-Cheng Kuo, Yu-Ming Wang, Yi-Jung Ho, Tein-Yao Chang, Zheng-Zong Lai, Pei-Yi Tsui, Tzong-Yuan Wu & Chang-Chi Lin. (2016) Suramin treatment reduces chikungunya pathogenesis in mice. Antiviral Research 134, pages 89-96.
Crossref
Sarah S. Long. (2016) Diagnosis and management of undifferentiated fever in children. Journal of Infection 72, pages S68-S76.
Crossref
Sunit Kumar Singh. 2015. Human Emerging and Re‐emerging Infections. Human Emerging and Re‐emerging Infections 177 188 .
Lucas Y.H. Goh, Yiu-Wing Kam, Stefan W. Metz, Jody Hobson-Peters, Natalie A. Prow, Suzi McCarthy, David W. Smith, Gorben P. Pijlman, Lisa F.P. Ng & Roy A. Hall. (2015) A sensitive epitope-blocking ELISA for the detection of Chikungunya virus-specific antibodies in patients. Journal of Virological Methods 222, pages 55-61.
Crossref
Thérèse Couderc & Marc Lecuit. (2015) Chikungunya virus pathogenesis: From bedside to bench. Antiviral Research 121, pages 120-131.
Crossref
Sarah K. Dotters-Katz, Matthew R. Grace, Robert A. Strauss, Nancy Chescheir & Jeffrey A. Kuller. (2015) Chikungunya Fever. Obstetrical & Gynecological Survey 70:7, pages 453-457.
Crossref
Lucas Goh, Jody Hobson-Peters, Natalie Prow, Kelly Baker, Thisun Piyasena, Carmel Taylor, Ashok Rana, Marcus Hastie, Jeff Gorman & Roy Hall. (2015) The Chikungunya Virus Capsid Protein Contains Linear B Cell Epitopes in the N- and C-Terminal Regions that are Dependent on an Intact C-Terminus for Antibody Recognition. Viruses 7:6, pages 2943-2964.
Crossref
Tien-Huang Chen, Shu-Wan Jian, Chih-Yuan Wang, Cheo Lin, Pei-Feng Wang, Chien-Ling Su, Hwa-Jen Teng, Pei-Yun Shu & Ho-Sheng Wu. (2015) Susceptibility of Aedes albopictus and Aedes aegypti to three imported Chikungunya virus strains, including the E1/226V variant in Taiwan. Journal of the Formosan Medical Association 114:6, pages 546-552.
Crossref
Lara J. Herrero, Adam Taylor, Stefan Wolf & Suresh Mahalingam. (2015) Arthropod-borne arthritides. Best Practice & Research Clinical Rheumatology 29:2, pages 259-274.
Crossref
Lucas Y. H. Goh, Jody Hobson-Peters, Natalie A. Prow, Joy Gardner, Helle Bielefeldt-Ohmann, Andreas Suhrbier & Roy A. Hall. (2015) Monoclonal antibodies specific for the capsid protein of chikungunya virus suitable for multiple applications. Journal of General Virology 96:3, pages 507-512.
Crossref
Anuj Sharma, Nagaraja S. Balakathiresan & Radha K. Maheshwari. (2015) Chikungunya Virus Infection Alters Expression of MicroRNAs Involved in Cellular Proliferation, Immune Response and Apoptosis. Intervirology 58:5, pages 332-341.
Crossref
Duncan R. Smith. (2015) Global protein profiling studies of chikungunya virus infection identify different proteins but common biological processes. Reviews in Medical Virology 25:1, pages 3-18.
Crossref
Yee Suan Poo, Penny A. Rudd, Joy Gardner, Jane A. C. Wilson, Thibaut Larcher, Marie-Anne Colle, Thuy T. Le, Helder I. Nakaya, David Warrilow, Richard Allcock, Helle Bielefeldt-Ohmann, Wayne A. Schroder, Alexander A. Khromykh, José A. Lopez & Andreas Suhrbier. (2014) Multiple Immune Factors Are Involved in Controlling Acute and Chronic Chikungunya Virus Infection. PLoS Neglected Tropical Diseases 8:12, pages e3354.
Crossref
Lee-Jah Chang, Kimberly A Dowd, Floreliz H Mendoza, Jamie G Saunders, Sandra Sitar, Sarah H Plummer, Galina Yamshchikov, Uzma N Sarwar, Zonghui Hu, Mary E Enama, Robert T Bailer, Richard A Koup, Richard M Schwartz, Wataru Akahata, Gary J Nabel, John R Mascola, Theodore C Pierson, Barney S Graham & Julie E Ledgerwood. (2014) Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial. The Lancet 384:9959, pages 2046-2052.
Crossref
Anastasija Shytuhina, Pavlo Pristatsky, Jian He, Danilo R. Casimiro, Richard M. Schwartz, Van M. Hoang & Sha Ha. (2014) Development and application of a reversed-phase high-performance liquid chromatographic method for quantitation and characterization of a Chikungunya virus-like particle vaccine. Journal of Chromatography A 1364, pages 192-197.
Crossref
Petra van den Doel, Asisa Volz, Jouke M. Roose, Varsha D. Sewbalaksing, Gorben P. Pijlman, Ingeborg van Middelkoop, Vincent Duiverman, Eva van de Wetering, Gerd Sutter, Albert D. M. E. Osterhaus & Byron E. E. Martina. (2014) Recombinant Modified Vaccinia Virus Ankara Expressing Glycoprotein E2 of Chikungunya Virus Protects AG129 Mice against Lethal Challenge. PLoS Neglected Tropical Diseases 8:9, pages e3101.
Crossref
Pankaj Pal, Julie M. Fox, David W. Hawman, Yan-Jang S. Huang, Ilhem Messaoudi, Craig Kreklywich, Michael Denton, Alfred W. Legasse, Patricia P. Smith, Syd Johnson, Michael K. Axthelm, Dana L. Vanlandingham, Daniel N. Streblow, Stephen Higgs, Thomas E. Morrison & Michael S. Diamond. (2014) Chikungunya Viruses That Escape Monoclonal Antibody Therapy Are Clinically Attenuated, Stable, and Not Purified in Mosquitoes. Journal of Virology 88:15, pages 8213-8226.
Crossref
Immacolata Iovinella, Paolo Pelosi & Barbara Conti. (2014) A rationale to design longer lasting mosquito repellents. Parasitology Research 113:5, pages 1813-1820.
Crossref
Lucas Y.H. Goh, Jody Hobson-Peters, Natalie A. Prow, Joy Gardner, Helle Bielefeldt-Ohmann, Alyssa T. Pyke, Andreas Suhrbier & Roy A. Hall. (2013) Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse model. Clinical Immunology 149:3, pages 487-497.
Crossref
Iranaia Assunção-Miranda, Christine Cruz-Oliveira & Andrea T. Da Poian. (2013) Molecular Mechanisms Involved in the Pathogenesis of Alphavirus-Induced Arthritis. BioMed Research International 2013, pages 1-11.
Crossref
Philippe Gasque. 2013. Viral Infections of the Human Nervous System. Viral Infections of the Human Nervous System 295 315 .
Shiril Kumar, Marie-Christine Jaffar-Bandjee, Claude Giry, Léa Connen de Kerillis, Andres Merits, Philippe Gasque & Jean-Jacques Hoarau. (2012) Mouse macrophage innate immune response to chikungunya virus infection. Virology Journal 9:1.
Crossref
Phitchayapak Wintachai, Nitwara Wikan, Atichat Kuadkitkan, Thitigun Jaimipuk, Sukathida Ubol, Rojjanaporn Pulmanausahakul, Prasert Auewarakul, Watchara Kasinrerk, Wen‐Yu Weng, Mingkwan Panyasrivanit, Atchara Paemanee, Suthathip Kittisenachai, Sittiruk Roytrakul & Duncan R. Smith. (2012) Identification of prohibitin as a Chikungunya virus receptor protein. Journal of Medical Virology 84:11, pages 1757-1770.
Crossref
Helder I. Nakaya, Joy Gardner, Yee‐Suan Poo, Lee Major, Bali Pulendran & Andreas Suhrbier. (2012) Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis. Arthritis & Rheumatism 64:11, pages 3553-3563.
Crossref
Lauren M. Neighbours, Kristin Long, Alan C. Whitmore & Mark T. Heise. (2012) Myd88-Dependent Toll-Like Receptor 7 Signaling Mediates Protection from Severe Ross River Virus-Induced Disease in Mice. Journal of Virology 86:19, pages 10675-10685.
Crossref
Shane P. McTigheRajeev Vaidyanathan. (2012) Vector Competence of Aedes albopictus from Virginia and Georgia for Chikungunya Virus Isolated in the Comoros Islands, 2005 . Vector-Borne and Zoonotic Diseases 12:10, pages 867-871.
Crossref
Bor Luen Tang. (2012) The cell biology of Chikungunya virus infection. Cellular Microbiology 14:9, pages 1354-1363.
Crossref
Andreas Suhrbier, Marie-Christine Jaffar-Bandjee & Philippe Gasque. (2012) Arthritogenic alphaviruses—an overview. Nature Reviews Rheumatology 8:7, pages 420-429.
Crossref
Eugene J. Kucharz & Ilona Cebula-Byrska. (2012) Chikungunya fever. European Journal of Internal Medicine 23:4, pages 325-329.
Crossref
Bizunesh Abere, Nitwara Wikan, Sukathida Ubol, Prasert Auewarakul, Atchara Paemanee, Suthathip Kittisenachai, Sittiruk Roytrakul & Duncan R. Smith. (2012) Proteomic Analysis of Chikungunya Virus Infected Microgial Cells. PLoS ONE 7:4, pages e34800.
Crossref
Nitwara Wikan, Prirayapak Sakoonwatanyoo, Sukathida Ubol, Sutee Yoksan & Duncan R. Smith. (2012) Chikungunya Virus Infection of Cell Lines: Analysis of the East, Central and South African Lineage. PLoS ONE 7:1, pages e31102.
Crossref
Christian A Devaux. (2012) Emerging and re-emerging viruses: A global challenge illustrated by Chikungunya virus outbreaks. World Journal of Virology 1:1, pages 11.
Crossref
Shashi S. Seshia, William T. Bingham, Fenella J. Kirkham & Venkatraman Sadanand. (2011) Nontraumatic Coma in Children and Adolescents: Diagnosis and Management. Neurologic Clinics 29:4, pages 1007-1043.
Crossref
Rojjanaporn Pulmanausahakul, Sittiruk Roytrakul, Prasert Auewarakul & Duncan R. Smith. (2011) Chikungunya in Southeast Asia: understanding the emergence and finding solutions. International Journal of Infectious Diseases 15:10, pages e671-e676.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.