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Review

Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases

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Pages 4735-4748 | Published online: 05 Nov 2020

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Meiqi Zhang, Yun Chen, Huan Chen, Ye Shen, Lingxiao Pang, Weihua Wu & Zhenfei Yu. (2022) Tanshinone IIA alleviates cardiac hypertrophy through m6A modification of galectin-3. Bioengineered 13:2, pages 4260-4270.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Qingjie Wang, Xiya Zhao, Yang Jiang, Biao Jin & Li Wang. (2023) Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants. Biomolecules 13:12, pages 1725.
Crossref
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Crossref
Jing-Yi Zeng, Yu Wang, Fu-Yuan Hong, Miao Miao, Yu-Ying Jiang, Zi-Xuan Qiao, Yun-Tao Wang & Xiao-Rong Bao. (2023) Tanshinone IIA is superior to paricalcitol in ameliorating tubulointerstitial fibrosis through regulation of VDR/Wnt/β-catenin pathway in rats with diabetic nephropathy. Naunyn-Schmiedeberg's Archives of Pharmacology.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Nan Ge, Guangli Yan, Hui Sun, Le Yang, Ling Kong, Ye Sun, Ying Han, Qiqi Zhao, Shuyu Kang & Xijun Wang. (2023) Version updates of strategies for drug discovery based on effective constituents of traditional Chinese medicine. Acupuncture and Herbal Medicine 3:3, pages 158-179.
Crossref
Lu Xiao, Xing-Juan Chen, Ji-Kang Feng, Wei-Na Li, Shuo Yuan & Ying Hu. (2023) Natural products as the calcium channel blockers for the treatment of arrhythmia: Advance and prospect. Fitoterapia 169, pages 105600.
Crossref
Lin Wen, Xie Cheng, Qigui Fan, Zixin Chen, Zixin Luo, Tiantian Xu, Ming He & Huan He. (2023) TanshinoneⅡA inhibits excessive autophagy and protects myocardium against ischemia/reperfusion injury via 14-3-3η/Akt/Beclin1 pathway. European Journal of Pharmacology 954, pages 175865.
Crossref
Min Liu, Chenhan Mao, Fusen Zhao, Zhaoyang Chen & Xindong Wang. (2023) The application and mechanism of Chinese medicine in the upstream treatment of atrial fibrillation. Frontiers in Cardiovascular Medicine 10.
Crossref
Wenbin Xiao, Kerui He, Chong Yu, Zeming Zhou, Liye Xia, Shibao Xie, Hanqi Li, Ming Zhang, Zhifeng Zhang, Pei Luo, Lu Wen & Gang Chen. (2023) Space Station-like Composite Nanoparticles for Co-Delivery of Multiple Natural Compounds from Chinese Medicine and Hydrogen in Combating Sensorineural Hearing Loss. Molecular Pharmaceutics 20:8, pages 3987-4006.
Crossref
Kajal sherawat & Sidharth Mehan. (2023) Tanshinone-IIA mediated neuroprotection by modulating neuronal pathways. Naunyn-Schmiedeberg's Archives of Pharmacology 396:8, pages 1647-1667.
Crossref
Shun Wu, Dingchun Lu, Babu Gajendran, Qilan Hu, Jian Zhang, Shengquan Wang, Minzhen Han, Yini Xu & Xiangchun Shen. (2023) Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1 . Phytotherapy Research 37:8, pages 3543-3558.
Crossref
Qinan Yin, Xiaoqin Zhang, Suqing Liao, Xiaobo Huang, Chunpeng Craig Wan & Yi Wang. (2023) Potential anticoagulant of traditional chinese medicine and novel targets for anticoagulant drugs. Phytomedicine 116, pages 154880.
Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Mengnan Liu, Ziyi Li, Yue Ouyang, Mingtai Chen, Xin Guo, Maryam Mazhar, Junli Kang, Hua Zhou, Qibiao Wu & Sijin Yang. (2023) Material basis and integrative pharmacology of danshen decoction in the treatment of cardiovascular diseases. Phytomedicine 108, pages 154503.
Crossref
Wenbing Zhi, Yang Liu, Xiumei Wang & Hong Zhang. (2023) Recent advances of traditional Chinese medicine for the prevention and treatment of atherosclerosis. Journal of Ethnopharmacology 301, pages 115749.
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Yuejin Xue, Liyuan Zhang, Lusha Zhang, Wei Sun, Zhirui Fang, Yuze Leng, Mengyao Li, Xiuyun Ren, Rui Zhang, Yingxue Zhang, Lu Chen & Hong Wang. (2022) Danshensu prevents thrombosis by inhibiting platelet activation via SIRT1/ROS/mtDNA pathways without increasing bleeding risk. Phytomedicine 104, pages 154271.
Crossref
Na Young Kim, Young Yun Jung, Min Hee Yang, Arunachalam Chinnathambi, Chandramohan Govindasamy, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough & Kwang Seok Ahn. (2022) Tanshinone IIA exerts autophagic cell death through down-regulation of β-catenin in renal cell carcinoma cells. Biochimie 200, pages 119-130.
Crossref
Yuting Yang, Jiehong Yang, Wei Fu, Peng Zhou, Yu He, Mingsun Fang, Haitong Wan & Huifen Zhou. (2022) Pharmacokinetic Comparison of Nine Bioactive Compounds of Guanxinshutong Capsule in Normal and Acute Myocardial Infarction Rats. European Journal of Drug Metabolism and Pharmacokinetics 47:5, pages 653-665.
Crossref
Guoxue Zhu, Xiaoqian Wu, Shujun Jiang, Yi Wang, Desong Kong, Yang Zhao & Wang Wang. (2022) The application of omics techniques to evaluate the effects of Tanshinone IIA on dextran sodium sulfate induced ulcerative colitis. Molecular Omics 18:7, pages 666-676.
Crossref
Lidan He, Xiuyan Wu, Xia Zhang, Xuemei Li, Xin Lin, Yameng Huang & Jianbo Wu. (2022) Puerarin protects against H2O2-induced apoptosis of HTR-8/SVneo cells by regulating the miR-20a-5p/VEGFA/Akt axis. Placenta 126, pages 202-208.
Crossref
Xu Wang, Jingjing Fa, Yuanjin Zhang, Shengbo Huang, Jie Liu, Junqing Gao, Lina Xing, Zongjun Liu & Xin Wang. (2022) Evaluation of Herb–Drug Interaction Between Danshen and Rivaroxaban in Rat and Human Liver Microsomes. Frontiers in Pharmacology 13.
Crossref
Mengqi Huo, Sha Peng, Jing Li, Yanfeng Cao, Zhao Chen, Yanling Zhang & Yanjiang Qiao. (2022) Comparison of the clinical effect features of Han-Ku-Gan and Wen-Xin-Gan based on the efficacy of promoting blood circulation and removing blood stasis. Journal of Traditional Chinese Medical Sciences 9:3, pages 237-245.
Crossref
Jianbo Zhou, Li Wang, Cheng Peng & Fu Peng. (2022) Co-Targeting Tumor Angiogenesis and Immunosuppressive Tumor Microenvironment: A Perspective in Ethnopharmacology. Frontiers in Pharmacology 13.
Crossref
YiWen LI, BinYu LUO, Jing CUI, MengMeng ZHU, Yue LIU, Hao XU, DaZhuo SHI & KeJi CHEN. (2022) Combination of disease and syndrome in coronary artery disease: prevention and treatment strategies. SCIENTIA SINICA Vitae 52:6, pages 797-811.
Crossref
Yue Su, Chu Wang, Hong Zhang, Lifang Guo, Yongshi Liang, Min Xiong, Xiaohua Feng, Daishi Chen, Zhaoyang Ke, Lu Wen & Gang Chen. (2022) Sonodynamic therapy exciting the herbal nanocomposite with spider-web-like effect to combat otitis media. International Journal of Pharmaceutics 621, pages 121820.
Crossref
Aarti Yadav, Surender Singh Yadav, Sandeep Singh & Rajesh Dabur. (2022) Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy. European Journal of Pharmacology 925, pages 174995.
Crossref
Mengnan Liu, Gang Yuan, Gang Luo, Xin Guo, Mingtai Chen, Huayi Yang, Fan He, Tingfu Yang, Xinyue Zhang, Qibiao Wu, Hua Zhou & Sijin Yang. (2022) Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-15.
Crossref
Qiang Fu, Mengya Huang, Lei Tang, Qi Zheng, Fujun Huang, Xun Zhou & Shumei Wang. (2022) Tanshinone Capsules Combined With Prednisone for Facial Seborrheic Dermatitis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Frontiers in Medicine 9.
Crossref
Hangchao Li, Lina Ji, Yingying Shen, Danqing Fu, Dijiong Wu & Baodong Ye. (2022) Bushen Jianpi Quyu Formula Alleviates Myelosuppression of an Immune-Mediated Aplastic Anemia Mouse Model via Inhibiting Expression of the PI3K/AKT/NF-κB Signaling Pathway. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-10.
Crossref
Jing-Yun Dou, Min Zhang, Huan Cen, Yi-Qin Chen, Yi-Fan Wu, Fuhua Lu, Jiuyao Zhou, Xu-Sheng Liu & Yue-Yu Gu. (2022) Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling. Frontiers in Pharmacology 13.
Crossref
Yueh-Lin Wu, Heng Lin, Hsiao-Fen Li, Ming-Jaw Don, Pei-Chih King & Hsi-Hsien Chen. (2022) Salvia miltiorrhiza Extract and Individual Synthesized Component Derivatives Induce Activating-Transcription-Factor-3-Mediated Anti-Obesity Effects and Attenuate Obesity-Induced Metabolic Disorder by Suppressing C/EBPα in High-Fat-Induced Obese Mice. Cells 11:6, pages 1022.
Crossref
Aneta Ostróżka-Cieślik. (2022) The Effect of Antioxidant Added to Preservation Solution on the Protection of Kidneys before Transplantation. International Journal of Molecular Sciences 23:6, pages 3141.
Crossref
Zi-Heng Li, Li Cheng, Chun Wen, Li Ding, Qiu-Yun You & Shun-Bo Zhang. (2022) Activation of CNR1/PI3K/AKT Pathway by Tanshinone IIA Protects Hippocampal Neurons and Ameliorates Sleep Deprivation-Induced Cognitive Dysfunction in Rats. Frontiers in Pharmacology 13.
Crossref
Sijie Tan, Wen Han Tong & Ajai Vyas. (2022) Impact of Plant-Based Foods and Nutraceuticals on Toxoplasma gondii Cysts: Nutritional Therapy as a Viable Approach for Managing Chronic Brain Toxoplasmosis. Frontiers in Nutrition 9.
Crossref
Jungyoon Choi, Seokjoo Chang, Eunjin Kim & Sang Yeon Min. (2022) Integrative treatment of herbal medicine with western medicine on coronary artery lesions in children with Kawasaki disease. Medicine 101:7, pages e28802.
Crossref
Haiwei Ni, Guojing Ruan, Cheng Sun, Xuan Yang, Zhenyan Miao, Jifei Li, Ying Chen, Hai Qin, Yichen Liu, Lufeng Zheng, Yingying Xing, Tao Xi & Xiaoman Li. (2021) Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis. Environmental Toxicology 37:2, pages 192-200.
Crossref
Anella Saviano, Simona De Vita, Maria Giovanna Chini, Noemi Marigliano, Gianluigi Lauro, Gian Marco Casillo, Federica Raucci, Maria Iorizzi, Robert Klaus Hofstetter, Katrin Fischer, Andreas Koeberle, Oliver Werz, Francesco Maione & Giuseppe Bifulco. (2022) In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway. Biomolecules 12:1, pages 99.
Crossref
Ying-Chyi Song, Cheng-Chieh Kuo, Chuan-Teng Liu, Tsai-Chen Wu, Yi-Ting Kuo & Hung-Rong Yen. (2022) Combined Effects of Tanshinone IIA and an Autophagy Inhibitor on the Apoptosis of Leukemia Cells via p53, Apoptosis-Related Proteins and Oxidative Stress Pathways. Integrative Cancer Therapies 21, pages 153473542211177.
Crossref
Huali Fan, Xiaofang Xie, Xi Kuang, Junrong Du & Fu Peng. (2022) MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine. The American Journal of Chinese Medicine 50:07, pages 1799-1825.
Crossref
Wenfeng Zhang, Cun Liu, Jie Li, Yiping Lu, Huayao Li, Jing Zhuang, Xin Ren, Mengmeng Wang & Changgang Sun. (2022) Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural Medicine. The American Journal of Chinese Medicine 50:01, pages 209-239.
Crossref
R. Mohanraj, R. Brindha, R. Kandeeban, M. Mahendhar, K. Saminathan & G. Ayyappadasan. (2021) Electrochemical detection of 5-hydroxytryptamine using sustainable SnO2-Graphite nanocomposite modified electrode. Materials Letters 305, pages 130796.
Crossref
Yize Sun, Zheyi Wang, Chunguo Wang, Zhuoran Tang & Haibin Zhao. (2021) Psycho-cardiology therapeutic effects of Shuangxinfang in rats with depression-behavior post acute myocardial infarction: Focus on protein S100A9 from proteomics. Biomedicine & Pharmacotherapy 144, pages 112303.
Crossref
Yong Guo, Fang-Fang Wang, Bing Xiang, Hong-Bing Ma & Yu-Ping Gong. (2021) Tanshinone IIA potentiates the efficacy of imatinib by regulating the AKT‑MDM2‑P53 signaling pathway in Philadelphia chromosome‑positive acute lymphoblastic leukemia. Oncology Letters 23:1.
Crossref
Chenhui Zhong, Zuan Lin, Liyuan Ke, Peiying Shi, Shaoguang Li, Liying Huang, Xinhua Lin & Hong Yao. (2021) Recent Research Progress (2015–2021) and Perspectives on the Pharmacological Effects and Mechanisms of Tanshinone IIA. Frontiers in Pharmacology 12.
Crossref
Peng Wang, Guilin Jiang, Wenjuan Ju, Yaping Cai, Jinrong Wang & Feihua Wu. (2021) Influence of Bushen Tiaochong Cycle Therapy on Th1/Th2 Deviation, Sex Hormone Level, and Pregnancy Outcome of Alloimmune Recurrent Spontaneous Abortion. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-7.
Crossref
Cheng-Ming Hsu, Ming-Yu Yang, Ming-Shao Tsai, Geng-He Chang, Yao-Hsu Yang, Yao-Te Tsai, Ching-Yuan Wu & Shun-Fu Chang. (2021) Dihydroisotanshinone I as a Treatment Option for Head and Neck Squamous Cell Carcinomas. International Journal of Molecular Sciences 22:16, pages 8881.
Crossref
Lalita Subedi & Bhakta Prasad Gaire. (2021) Tanshinone IIA: A phytochemical as a promising drug candidate for neurodegenerative diseases. Pharmacological Research 169, pages 105661.
Crossref
Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu & Xisong Ke. (2021) Tanshinones induce tumor cell apoptosis via directly targeting FHIT. Scientific Reports 11:1.
Crossref