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Review

Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy

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Pages 303-328 | Published online: 18 Mar 2021

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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Iver Petersen. (2021) Classification and Treatment of Diseases in the Age of Genome Medicine Based on Pathway Pathology. International Journal of Molecular Sciences 22:17, pages 9418.
Crossref
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Crossref
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