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Review

Medication-overuse headache: a review

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Pages 367-378 | Published online: 26 Jun 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Halil Onder, Mehmet Hamamci, Murat Alpua & Ersin Kasım Ulusoy. (2019) Comorbid fibromyalgia in migraine patients: clinical significance and impact on daily life. Neurological Research 41:10, pages 909-915.
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Abouch V. Krymchantowski & Carla da Cunha Jevoux. (2017) Medication-overuse headache. Despite the advances in understanding it, treatment evidence still lacks. Expert Review of Neurotherapeutics 17:11, pages 1055-1058.
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Delphine Magis. (2015) Neuromodulation in migraine: state of the art and perspectives. Expert Review of Medical Devices 12:3, pages 329-339.
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Articles from other publishers (41)

Samita Giri, Erling Tronvik, Mattias Linde, Sindre Andre Pedersen & Knut Hagen. (2023) Randomized controlled studies evaluating Topiramate, Botulinum toxin type A, and mABs targeting CGRP in patients with chronic migraine and medication overuse headache: A systematic review and meta-analysis. Cephalalgia 43:4, pages 033310242311569.
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Arão Oliveira, Isabela Bensenor, Alessandra Goulart, Juliane Mercante & Mario Peres. (2023) Socioeconomic and geographic inequalities in headache disability in Brazil: The 2019 National Health Survey. Headache: The Journal of Head and Face Pain 63:1, pages 114-126.
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Gopal Nambi, Mshari Alghadier, Elturabi Elsayed Ebrahim, Arul Vellaiyan, Jaya Shanker Tedla, Ravi Shankar Reddy, Venkata Nagaraj Kakaraparthi, Osama R. Aldhafian, Naif N. Alshahrani & Ayman K. Saleh. (2022) Comparative Effects of Mulligan’s Mobilization, Spinal Manipulation, and Conventional Massage Therapy in Cervicogenic Headache—A Prospective, Randomized, Controlled Trial. Healthcare 11:1, pages 107.
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Samita Giri, Erling Tronvik, Mattias Linde & Knut Hagen. (2022) The impact of topiramate, botulinum toxin type A, and CGRP-antibodies on medication overuse headache in patients with chronic migraine: A protocol for systematic review and meta-analysis. Cephalalgia Reports 5, pages 251581632210968.
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Paolo Martelletti. 2022. Migraine in Medicine. Migraine in Medicine 453 637 .
Karlee Burns, Ryan Tierney & Jane McDevitt. (2021) Prescription Medication for Posttraumatic Headache Following Concussion: A Critically Appraised Topic. International Journal of Athletic Therapy and Training 26:6, pages 314-317.
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Klairton Duarte de Freitas & Raimundo Neudson Maia Alcantara. (2021) Analgesic abuse headache: risk factors and causes of poor adherence in the detox process. Headache Medicine 12:2, pages 110-117.
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Tiffani J. Mungoven, Luke A. Henderson & Noemi Meylakh. (2021) Chronic Migraine Pathophysiology and Treatment: A Review of Current Perspectives. Frontiers in Pain Research 2.
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Kinley Roberts, Linda Harrington & Sinéad M. Murphy. (2020) Headache in the neurology clinic: a 2-year audit. Irish Journal of Medical Science (1971 -) 190:3, pages 1143-1148.
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Elise Øien Sørnes, Ajay Risal, Kedar Manandhar, Hallie Thomas, Timothy J Steiner & Mattias Linde. (2021) Use of medicinal plants for headache, and their potential implication in medication-overuse headache: Evidence from a population-based study in Nepal. Cephalalgia 41:5, pages 561-581.
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Hans‐Christoph Diener, Michael J. Marmura, Stewart J. Tepper, Robert Cowan, Amaal J. Starling, Merle L. Diamond, Joe Hirman, Lahar Mehta, Thomas Brevig, Bjørn Sperling & Roger Cady. (2020) Efficacy, tolerability, and safety of eptinezumab in patients with a dual diagnosis of chronic migraine and medication‐overuse headache: Subgroup analysis of PROMISE‐2. Headache: The Journal of Head and Face Pain 61:1, pages 125-136.
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V. V. Osipova, K. V. Skorobogatykh, A. R. Artemenko & A. V. Sergeev. (2020) Severe drug-induced headache with its possible recurrent statuses in a patient with chronic tension headache. Neurology, Neuropsychiatry, Psychosomatics 12:4, pages 73-78.
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Lidiya D. Sadretdinova & Khristina P. Derevyanko. (2020) Drug-induced headache in young people of reproductive age with tobacco addiction. Medical Journal of the Russian Federation 26:1, pages 28-32.
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Caroline Bonnet & Patrick Delmas. (2020) L’activation des canaux Nav1.9 par le monoxyde d’azote à l’origine des céphalées par abus médicamenteux. médecine/sciences 36:1, pages 16-19.
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Ajal M. Dave, Jay C. Erickson & Brett J. Theeler. 2020. Traumatic Brain Injury. Traumatic Brain Injury 159 180 .
Willem Sebastiaan van Hoogstraten & Antoinette MaassenVanDenBrink. (2019) The need for new acutely acting antimigraine drugs: moving safely outside acute medication overuse. The Journal of Headache and Pain 20:1.
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Arão Belitardo OliveiraReinaldo Teixeira RibeiroMarco Tulio MelloSergio TufikMario Fernando Prieto Peres. (2019) Anandamide Is Related to Clinical and Cardiorespiratory Benefits of Aerobic Exercise Training in Migraine Patients: A Randomized Controlled Clinical Trial. Cannabis and Cannabinoid Research 4:4, pages 275-284.
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Benjamin R Wakerley. (2019) Medication-overuse headache. Practical Neurology 19:5, pages 399-403.
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Caroline Bonnet, Jizhe Hao, Nancy Osorio, Anne Donnet, Virginie Penalba, Jérôme Ruel & Patrick Delmas. (2019) Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache. Nature Communications 10:1.
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Mia Nielsen, Louise Ninett Carlsen, Signe Bruun Munksgaard, Ida Maria Storm Engelstoft, Rigmor Højland Jensen & Lars Bendtsen. (2019) Complete withdrawal is the most effective approach to reduce disability in patients with medication-overuse headache: A randomized controlled open-label trial. Cephalalgia 39:7, pages 863-872.
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Meaghan Kelly, Jeffrey Strelzik, Raquel Langdon & Marc DiSabella. (2018) Pediatric headache. Current Opinion in Pediatrics 30:6, pages 748-754.
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Abouch V. Krymchantowski, Ana Gabriela Ferreira Krymchantowski & Carla da Cunha Jevoux. (2018) Medication-overuse headache. Retrospective comparison of preventive treatments. Arquivos de Neuro-Psiquiatria 76:10, pages 668-673.
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I. Corbelli, P. Sarchielli, P. Eusebi, L. M. Cupini, S. Caproni, P. Calabresi, A. Pini, S. Guerzoni, P. Livrea, P. Prudenzano, G. Bernardi, M. Diomedi, G. Tedeschi, A. Tessitore, A. Russo, F. Pisani, R. Pisani, G. Bono, C. Zandrini, G. Misaggi, V. Di Piero, L. DiClemente, M. Squitieri, E. Vicenzini, B. Petolicchio, G. Sandrini, M. Allena & M. Berlangeri. (2018) Early management of patients with medication‐overuse headache: results from a multicentre clinical study. European Journal of Neurology 25:8, pages 1027-1033.
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Manish Bathla, Akshit Mahajan, Shazia Anjum & Saminder Panchal. (2018) Prolonged Abuse of Vasograin Tablets. Indian Journal of Private Psychiatry 12:1, pages 27-28.
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K. B. Alstadhaug, H. K. Ofte & E. S. Kristoffersen. (2018) Prävention und Therapie des MedikamentenübergebrauchskopfschmerzesPreventing and treating medication overuse headache. Der Schmerz 32:3, pages 201-206.
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Anne Mucha, Cara Troutman-Enseki & Tim Rylander. 2018. Physical Therapy Management of Concussion. Physical Therapy Management of Concussion 1 22 .
Gerd-Marie Eskerud Harris, Mollie Wood, Malin Eberhard-Gran, Christofer Lundqvist & Hedvig Nordeng. (2017) Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine. BMC Pregnancy and Childbirth 17:1.
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Zhiye Chen, Zhihua Jia, Xiaoyan Chen, Mengqi Liu, Shuangfeng Liu, Lin Ma & Shengyuan Yu. (2017) Volumetric abnormalities of thalamic subnuclei in medication-overuse headache. The Journal of Headache and Pain 18:1.
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E. S. Kristoffersen, J. Straand, J. Š. Benth, M. B. Russell & C. Lundqvist. (2017) Predictors of successful primary care detoxification treatment for medication-overuse headache. Acta Neurologica Scandinavica 136:5, pages 486-494.
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Jennifer Y Xie, Milena De Felice, Caroline M Kopruszinski, Nathan Eyde, Justin LaVigne, Bethany Remeniuk, Pablo Hernandez, Xu Yue, Naomi Goshima, Michael Ossipov, Tamara King, John M Streicher, Edita Navratilova, David Dodick, Hugh Rosen, Ed Roberts & Frank Porreca. (2017) Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. Cephalalgia 37:8, pages 780-794.
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Karl B. Alstadhaug, Hilde K. Ofte & Espen S. Kristoffersen. (2017) Preventing and treating medication overuse headache. PAIN Reports 2:4, pages e612.
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Raquel Langdon & Marc T. DiSabella. (2017) Pediatric Headache: An Overview. Current Problems in Pediatric and Adolescent Health Care 47:3, pages 44-65.
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Linda Hanson, Mitchell Haas, Gert Bronfort, Darcy Vavrek, Craig Schulz, Brent Leininger, Roni Evans, Leslie Takaki & Moni Neradilek. (2016) Dose–response of spinal manipulation for cervicogenic headache: study protocol for a randomized controlled trial. Chiropractic & Manual Therapies 24:1.
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Ninett Louise Find, Rossana Terlizzi, Signe Bruun Munksgaard, Lars Bendtsen, Cristina Tassorelli, Giuseppe Nappi, Zaza Katsarava, Miguel Lainez, Maria Teresa Goicochea, Beatriz Shand, Ricardo Fadic, Santiago Spadafora, Marco Pagani & Rigmor Jensen. (2016) Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study. The Journal of Headache and Pain 17:1.
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Blaine Jacobs & Gregory Dussor. (2016) Neurovascular contributions to migraine: Moving beyond vasodilation. Neuroscience 338, pages 130-144.
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Linda Lu BachJoshana Goga. (2016) Management of migraine headaches in a chronic pain patient: A case report. Mental Health Clinician 6:3, pages 154-158.
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Naglaa A. El-Sherbiny, Mohamed Masoud, Nevin M. Shalaby & Hatem S. Shehata. (2015) Prevalence of primary headache disorders in Fayoum Governorate, Egypt. The Journal of Headache and Pain 16:1.
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Beatriz Shand, Maria Teresa Goicochea, Raul Valenzuela, Ricardo Fadic, Rigmor Jensen, Cristina Tassorelli & Giuseppe Nappi. (2015) Clinical and Demographical Characteristics of Patients with Medication Overuse Headache in Argentina and Chile: Analysis of the Latin American Section of COMOESTAS Project. The Journal of Headache and Pain 16:1.
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Maria Lurenda Westergaard, Ebba Holme Hansen, Charlotte Glümer & Rigmor Højland Jensen. (2015) Prescription pain medications and chronic headache in Denmark: implications for preventing medication overuse. European Journal of Clinical Pharmacology 71:7, pages 851-860.
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Carolina Burgos-Vega, Jamie Moy & Gregory Dussor. 2015. Molecular and Cell Biology of Pain. Molecular and Cell Biology of Pain 537 564 .
Stefano Caproni, Elisa Bianchi, Letizia M Cupini, Ilenia Corbelli, Ettore Beghi, Paolo Calabresi & Paola Sarchielli. (2014) Long term headache duration is a factor predicting nonresponse to detoxification and advice in medication overuse headache. The Journal of Headache and Pain 15:1.
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