231
Views
44
CrossRef citations to date
0
Altmetric
Review

Medication-overuse headache: a review

&
Pages 367-378 | Published online: 26 Jun 2014

References

  • JensenRStovnerLJEpidemiology and comorbidity of headacheLancet Neurol20087435436118339350
  • LindeMGustavssonAStovnerLJThe cost of headache disorders in Europe: the Eurolight projectEur J Neurol201219570371122136117
  • StovnerLHagenKJensenRThe global burden of headache: a documentation of headache prevalence and disability worldwideCephalalgia200727319321017381554
  • VosTFlaxmanADNaghaviMYears lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet201238098592163219623245607
  • AasethKGrandeRBKvaernerKJGulbrandsenPLundqvistCRussellMBPrevalence of secondary chronic headaches in a population-based sample of 30–44-year-old persons. The Akershus study of chronic headacheCephalalgia200828770571318498398
  • GrandeRBAasethKGulbrandsenPLundqvistCRussellMBPrevalence of primary chronic headache in a population-based sample of 30- to 44-year-old persons. The Akershus study of chronic headacheNeuroepidemiology2008302768318277081
  • Lantéri-MinetMAurayJPEl HasnaouiAPrevalence and description of chronic daily headache in the general population in FrancePain20031021–214314912620605
  • CastilloJMunozPGuiteraVPascualJKaplan Award 1998. Epidemiology of chronic daily headache in the general populationHeadache199839319019615613213
  • Headache Classification Committee of the International Headache SocietyThe International Classification of Headache Disorders. 3rd ed (beta version)Cephalalgia201333962980823771276
  • LatinovicRGullifordMRidsdaleLHeadache and migraine in primary care: consultation, prescription, and referral rates in a large populationJ Neurol Neurosurg Psychiatry200677338538716484650
  • RidsdaleLClarkLVDowsonAJHow do patients referred to neurologists for headache differ from those managed in primary care?Br J Gen Pract20075753838839517504590
  • PattersonVHEsmondeTFComparison of the handling of neurological outpatient referrals by general physicians and a neurologistJ Neurol Neurosurg Psychiatry19935678308331364
  • ZwartJADybGHagenKSvebakSStovnerLJHolmenJAnalgesic overuse among subjects with headache, neck, and low-back painNeurology20046291540154415136678
  • ZwartJADybGHagenKAnalgesic use: a predictor of chronic pain and medication overuse headacheNeurology200361216016412874392
  • EggenAEThe Tromso Study: frequency and predicting factors of analgesic drug use in a free-living population (12–56 years)J Clin Epidemiol19934611129713048229107
  • AntonovKIIsacsonDGPrescription and nonprescription analgesic use in SwedenAnn Pharmacother19983244854949562147
  • MehuysEPaemeleireKVan HeesTSelf-medication of regular headache: a community pharmacy-based surveyEur J Neurol20121981093109922360745
  • PorteousTBondCHannafordPSinclairHHow and why are non-prescription analgesics used in Scotland?Fam Pract2005221788515640291
  • HargreaveMAndersenTVNielsenAMunkCLiawKLKjaerSKFactors associated with continuous regular analgesic use – a population-based study of more than 45,000 Danish women and men 18–45 years of agePharmacoepidemiol Drug Saf2010191657419757417
  • HortonBTPetersGAClinical manifestations of excessive use of ergotamine preparations and mangement of withdrawal effect: report of 52 casesHeadache1963221422713964041
  • PetersGAHortonBTHeadache: with special reference to the excessive use of ergotamine preparations and withdrawal effectsProc Staff Meet Mayo Clin195126915316114827944
  • PetersGAHortonBTHeadache; with special reference to the excessive use of ergotamine tartrate and dihydroergotamineJ Lab Clin Med195036697297314795057
  • MathewNTKurmanRPerezFDrug induced refractory headache-clinical features and managementHeadache199030106346382272811
  • DienerHCDichgansJScholzEGeiselhartSGerberWDBilleAAnalgesic-induced chronic headache: long-term results of withdrawal therapyJ Neurol198923619142915233
  • KudrowLParadoxical effects of frequent analgesic useAdv Neurol1982333353417055014
  • EversSJensenREuropean Federation of Neurological SocietiesTreatment of medication overuse headache – guideline of the EFNS headache panelEur J Neurol20111891115112121834901
  • DienerHCLimmrothVMedication-overuse headache: a worldwide problemLancet Neurol20043847548315261608
  • KatsaravaZJensenRMedication-overuse headache: where are we now?Curr Opin Neurol200720332633017495628
  • RossiPJensenRNappiGAllenaMCOMOESTAS ConsortiumA narrative review on the management of medication overuse headache: the steep road from experience to evidenceJ Headache Pain200910640741719802522
  • EversSMarziniakMClinical features, pathophysiology, and treatment of medication-overuse headacheLancet Neurol20109439140120298963
  • KristoffersenESLundqvistCMedication-overuse headache: epidemiology, diagnosis and treatmentTher Adv Drug Saf2014528799
  • Ad Hoc Committee on Classification of Headache of the National Institute of HealthClassification of headacheJAMA1962179717718
  • Headache Classification Committee of the International Headache SocietyClassification and diagnostic criteria for headache disorders, cranial neuralgias and facial painCephalalgia19888Suppl 7196
  • Headache Classification Committee of the International Headache SocietyThe International Classification of Headache Disorders: 2nd edCephalalgia200424Suppl 1916014979299
  • CephalalgiaErratumCephalalgia2006263360
  • OlesenJBousserMGDienerHCNew appendix criteria open for a broader concept of chronic migraineCephalalgia200626674274616686915
  • SilbersteinSDOlesenJBousserMGThe International Classification of Headache Disorders, 2nd ed (ICHD-II) – revision of criteria for 8.2 Medication-overuse headacheCephalalgia200525646046515910572
  • Sun-EdelsteinCBigalMERapoportAMChronic migraine and medication overuse headache: clarifying the current International Headache Society classification criteriaCephalalgia200929444545219291245
  • GrazziLBussoneGMedication overuse headache (MOH): complication of migraine or secondary headache?Neurol Sci201233Suppl 1S27S2822644165
  • JonssonPHedenrudTLindeMEpidemiology of medication overuse headache in the general Swedish populationCephalalgia20113191015102221628444
  • LuSRFuhJLChenWTJuangKDWangSJChronic daily headache in Taipei, Taiwan: prevalence, follow-up and outcome predictorsCephalalgia2001211098098611843870
  • WiendelsNJKnuistingh NevenARosendaalFRChronic frequent headache in the general population: prevalence and associated factorsCephalalgia200626121434144217116093
  • ColásRMuñozPTempranoRGómezCPascualJChronic daily headache with analgesic overuse: epidemiology and impact on quality of lifeNeurology20046281338134215111671
  • StraubeAPfaffenrathVLadwigKHPrevalence of chronic migraine and medication overuse headache in Germany – the German DMKG Headache StudyCephalalgia201030220721319489879
  • WestergaardMLHansenEHGlumerCOlesenJJensenRHDefinitions of medication-overuse headache in population-based studies and their implications on prevalence estimates: a systematic reviewCephalalgia201434640942524293089
  • HagenKLindeMSteinerTJStovnerLJZwartJARisk factors for medication-overuse headache: an 11-year follow-up study. The Nord-Trøndelag Health StudiesPain20121531566122018971
  • WangSJFuhJLLuSRChronic daily headache in Chinese elderly: prevalence, risk factors, and biannual follow-upNeurology200054231431910668689
  • PrencipeMCasiniARFerrettiCPrevalence of headache in an elderly population: attack frequency, disability, and use of medicationJ Neurol Neurosurg Psychiatry200170337738111181862
  • WangSJFuhJLLuSRJuangKDChronic daily headache in adolescents: prevalence, impact, and medication overuseNeurology200666219319716434652
  • DybGHolmenTLZwartJAAnalgesic overuse among adolescents with headache: the Head-HUNT-Youth StudyNeurology200666219821016434653
  • PiazzaFChiappediMMaffiolettiEGalliFBalottinUMedication overuse headache in school-aged children: more common than expected?Headache201252101506151022822711
  • WiendelsNJvan der GeestMCNevenAKFerrariMDLaanLAChronic daily headache in children and adolescentsHeadache200545667868315953300
  • MeskunasCATepperSJRapoportAMSheftellFDBigalMEMedications associated with probable medication overuse headache reported in a tertiary care headache center over a 15-year periodHeadache200646576677216643579
  • KristoffersenESGrandeRBAasethKLundqvistCRussellMBManagement of primary chronic headache in the general population: the Akershus study of chronic headacheJ Headache Pain201213211312021993986
  • KristoffersenESLundqvistCAasethKGrandeRBRussellMBManagement of secondary chronic headache in the general population: the Akershus study of chronic headacheJ Headache Pain2013141523565808
  • ScherAILiptonRBStewartWFBigalMPatterns of medication use by chronic and episodic headache sufferers in the general population: results from the frequent headache epidemiology studyCephalalgia201030332132819614708
  • ZeebergPOlesenJJensenRProbable medication-overuse headache: the effect of a 2-month drug-free periodNeurology200666121894189816707727
  • Tfelt-HansenPCDienerHCWhy should American headache and migraine patients still be treated with butalbital-containing medicine?Headache201252467267422404123
  • LimmrothVKatsaravaZFritscheGPrzywaraSDienerHCFeatures of medication overuse headache following overuse of different acute headache drugsNeurology20025971011101412370454
  • Creac’hCRadatFMickGOne or several types of triptan overuse headaches?Headache200949451952819245390
  • JonssonPLindeMHensingGHedenrudTSociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headacheJ Headache Pain201213428129022427000
  • BekkelundSISalvesenRDrug-associated headache is unrecognized in patients treated at a neurological centreActa Neurol Scand2002105212012311903122
  • DowsonAJAnalysis of the patients attending a specialist UK headache clinic over a 3-year periodHeadache2003431141812864753
  • BigalMELiptonRBExcessive acute migraine medication use and migraine progressionNeurology200871221821182819029522
  • BigalMERapoportAMSheftellFDTepperSJLiptonRBTransformed migraine and medication overuse in a tertiary headache centre – clinical characteristics and treatment outcomesCephalalgia200424648349015154858
  • Lanteri-MinetMDuruGMudgeMCottrellSQuality of life impairment, disability and economic burden associated with chronic daily headache, focusing on chronic migraine with or without medication overuse: a systematic reviewCephalalgia201131783785021464078
  • WiendelsNJvan HaestregtAKnuistingh NevenAChronic frequent headache in the general population: comorbidity and quality of lifeCephalalgia200626121443145017116094
  • BendtsenLMunksgaardSTassorelliCDisability, anxiety and depression associated with medication-overuse headache can be considerably reduced by detoxification and prophylactic treatment. Results from a multicentre, multinational study (COMOESTAS project)Cephalalgia201434642643324322480
  • MunksgaardSBBendtsenLJensenRHTreatment-resistant medication overuse headache can be curedHeadache20125271120112922724425
  • WallaschTMKroppPMultidisciplinary integrated headache care: a prospective 12-month follow-up observational studyJ Headache Pain201213752152922790281
  • SteinerTCan we know the prevalence of MOH?Cephalalgia201434640340424500815
  • BahraAWalshMMenonSGoadsbyPJDoes chronic daily headache arise de novo in association with regular use of analgesics?Headache200343317919012603636
  • MunksgaardSBBendtsenLJensenRHDetoxification of medication-overuse headache by a multidisciplinary treatment programme is highly effective: a comparison of two consecutive treatment methods in an open-label designCephalalgia2012321183484422751965
  • HagenKVattenLStovnerLJZwartJAKrokstadSBovimGLow socio-economic status is associated with increased risk of frequent headache: a prospective study of 22718 adults in NorwayCephalalgia200222867267912383064
  • AtasoyHTUnalAEAtasoyNEmreUSumerMLow income and education levels may cause medication overuse and chronicity in migraine patientsHeadache2005451253115663609
  • RadatFCreac’hCSwendsenJDPsychiatric comorbidity in the evolution from migraine to medication overuse headacheCephalalgia200525751952215955038
  • ZwartJADybGHagenKDepression and anxiety disorders associated with headache frequency. The Nord-Trondelag Health StudyEur J Neurol200310214715212603289
  • CupiniLMDeMMCostaCObsessive-compulsive disorder and migraine with medication-overuse headacheHeadache20094971005101319496831
  • CevoliSSancisiEGrimaldiDFamily history for chronic headache and drug overuse as a risk factor for headache chronificationHeadache200949341241819267785
  • BigalMELiptonRBOveruse of acute migraine medications and migraine chronificationCurr Pain Headache Rep200913430130719586594
  • DodickDWDebate: analgesic overuse is a cause, not consequence, of chronic daily headache. Analgesic overuse is not a cause of chronic daily headacheHeadache200242654755412167149
  • TepperSJDebate: analgesic overuse is a cause, not consequence, of chronic daily headache. Analgesic overuse is a cause of chronic daily headacheHeadache200242654354712167148
  • PaemeleireKBahraAEversSMatharuMSGoadsbyPJMedication-overuse headache in patients with cluster headacheNeurology200667110911316832088
  • WilkinsonSMBeckerWJHeineJAOpiate use to control bowel motility may induce chronic daily headache in patients with migraineHeadache200141330330911264692
  • CevoliSMochiMScapoliCA genetic association study of dopamine metabolism-related genes and chronic headache with drug abuseEur J Neurol20061391009101316930369
  • Di LorenzoCDi LorenzoGSancesGDrug consumption in medication overuse headache is influenced by brain-derived neurotrophic factor Val66Met polymorphismJ Headache Pain200910534935519517061
  • Di LorenzoCSancesGDi LorenzoGThe wolframin His611Arg polymorphism influences medication overuse headacheNeurosci Lett2007424317918417719176
  • CargninSVianaMGhiottoNFunctional polymorphisms in COMT and SLC6A4 genes influence the prognosis of patients with medication overuse headache after withdrawal therapyEur J Neurol Epub2014329
  • CupiniLMSarchielliPCalabresiPMedication overuse headache: neurobiological, behavioural and therapeutic aspectsPain2010150222222420546999
  • De FeliceMOssipovMHWangRTriptan-induced latent sensitization: a possible basis for medication overuse headacheAnn Neurol201067332533720373344
  • MengIDDodickDOssipovMHPorrecaFPathophysiology of medication overuse headache: insights and hypotheses from preclinical studiesCephalalgia201131785186021444643
  • Bongsebandhu-phubhakdiSSrikiatkhachornAPathophysiology of medication-overuse headache: implications from animal studiesCurr Pain Headache Rep201216111011522076674
  • SrikiatkhachornAAnthonyMSerotonin receptor adaptation in patients with analgesic-induced headacheCephalalgia20061664194228902250
  • SrikiatkhachornAManeesriSGovitrapongPKasantikulVDerangement of serotonin system in migrainous patients with analgesic abuse headache: clues from plateletsHeadache199838143499505003
  • SupornsilpchaiWSanguanrangsirikulSManeesriSSrikiatkhachornASerotonin depletion, cortical spreading depression, and trigeminal nociceptionHeadache2006461343916412149
  • le GrandSMSupornsilpchaiWSaengjaroenthamCSrikiatkhachornASerotonin depletion leads to cortical hyperexcitability and trigeminal nociceptive facilitation via the nitric oxide pathwayHeadache20115171152116021649655
  • SupornsilpchaiWle GrandSMSrikiatkhachornACortical hyperexcitability and mechanism of medication-overuse headacheCephalalgia20103091101110920713560
  • SupornsilpchaiWle GrandSMSrikiatkhachornAInvolvement of pro-nociceptive 5-HT2A receptor in the pathogenesis of medication-overuse headacheHeadache201050218519720039957
  • BelangerSMaWChabotJGQuirionRExpression of calcitonin gene-related peptide, substance P and protein kinase C in cultured dorsal root ganglion neurons following chronic exposure to mu, delta and kappa opiatesNeuroscience2002115244145312421610
  • PerrottaASerraoMSandriniGSensitisation of spinal cord pain processing in medication overuse headache involves supraspinal pain controlCephalalgia201030327228419614707
  • AyzenbergIObermannMNyhuisPCentral sensitization of the trigeminal and somatic nociceptive systems in medication overuse headache mainly involves cerebral supraspinal structuresCephalalgia20062691106111416919061
  • MunksgaardSBBendtsenLJensenRHModulation of central sensitisation by detoxification in MOH: Results of a 12-month detoxification studyCephalalgia201333744445323431023
  • CupiniLMCostaCSarchielliPDegradation of endocannabinoids in chronic migraine and medication overuse headacheNeurobiol Dis200830218618918358734
  • RossiCPiniLACupiniMLCalabresiPSarchielliPEndocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: relation with serotonin levelsEur J Clin Pharmacol20086411818004553
  • SarchielliPRaineroICoppolaFInvolvement of corticotrophin-releasing factor and orexin-A in chronic migraine and medication-overuse headache: findings from cerebrospinal fluidCephalalgia200828771472218479471
  • ChanraudSDi ScalaGDilharreguyBSchoenenJAllardMRadatFBrain functional connectivity and morphology changes in medication-overuse headache: Clue for dependence-related processes?Cephalalgia Epub2014121
  • FerraroSGrazziLMuffattiRIn medication-overuse headache, fMRI shows long-lasting dysfunction in midbrain areasHeadache201252101520153423094707
  • GrazziLChiappariniLFerraroSChronic migraine with medication overuse pre-post withdrawal of symptomatic medication: clinical results and fMRI correlationsHeadache2010506998100420618816
  • FumalALaureysSDi ClementeLOrbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraineBrain2006129Pt 254355016330505
  • CalabresiPCupiniLMMedication-overuse headache: similarities with drug addictionTrends Pharmacol Sci2005262626815681022
  • SaperJRLakeAE3rdMedication overuse headache: type I and type IICephalalgia20062610126216961800
  • LakeAE3rdMedication overuse headache: biobehavioral issues and solutionsHeadache200646Suppl 3S88S9717034403
  • BendtsenLEversSLindeMEFNS guideline on the treatment of tension-type headache – report of an EFNS task forceEur J Neurol201017111318132520482606
  • EversSAfraJFreseAEFNS guideline on the drug treatment of migraine – revised report of an EFNS task forceEur J Neurol200916996898119708964
  • AbbottFVFraserMIUse and abuse of over-the-counter analgesic agentsJ Psychiatry Neurosci199823113349505057
  • CooperRJOver-the-counter medicine abuse – a review of the literatureJ Subst Use20131828210723525509
  • CooperRJ‘I can’t be an addict. I am.’ Over-the-counter medicine abuse: a qualitative studyBMJ Open201336
  • GossopMDarkeSGriffithsPThe Severity of Dependence Scale (SDS): psychometric properties of the SDS in English and Australian samples of heroin, cocaine and amphetamine usersAddiction19959056076147795497
  • GrandeRBAasethKSaltyte BenthJGulbrandsenPRussellMBLundqvistCThe Severity of Dependence Scale detects people with medication overuse: the Akershus study of chronic headacheJ Neurol Neurosurg Psychiatry200980778478919279030
  • LundqvistCAasethKGrandeRBBenthJSRussellMBThe severity of dependence score correlates with medication overuse in persons with secondary chronic headaches. The Akershus study of chronic headachePain2010148348749120071079
  • LundqvistCBenthJSGrandeRBAasethKRussellMBAn adapted Severity of Dependence Scale is valid for the detection of medication overuse: the Akershus study of chronic headacheEur J Neurol201118351251820825471
  • LundqvistCGrandeRBAasethKRussellMBDependence scores predict prognosis of medication overuse headache: a prospective cohort from the Akershus study of chronic headachePain2012153368268622281099
  • FuhJLWangSJLuSRJuangKDDoes medication overuse headache represent a behavior of dependence?Pain20051191–3495516298069
  • RadatFCreac’hCGuegan-MassardierEBehavioral dependence in patients with medication overuse headache: a cross-sectional study in consulting patients using the DSM-IV criteriaHeadache20084871026103618081820
  • LauwerierEPaemeleireKVan DammeSGoubertLCrombezGMedication use in patients with migraine and medication-overuse headache: the role of problem-solving and attitudes about pain medicationPain201115261334133921396772
  • GalliFPozziGFrustaciADifferences in the personality profile of medication-overuse headache sufferers and drug addict patients: a comparative study using MMPI-2Headache20115181212122721884080
  • SancesGGalliFAnastasiSMedication-overuse headache and personality: a controlled study by means of the MMPI-2Headache201050219820920039955
  • FerrariACiceroAFBertoliniALeoneSPasciulloGSternieriENeed for analgesics/drugs of abuse: a comparison between headache patients and addicts by the Leeds Dependence Questionnaire (LDQ)Cephalalgia200626218719316426274
  • JonssonPJakobssonAHensingGLindeMMooreCDHedenrudTHolding on to the indispensable medication – a grounded theory on medication use from the perspective of persons with medication overuse headacheJ Headache Pain20131414323697986
  • SaperJRHamelRLLakeIII AEMedication overuse headache (MOH) is a biobehavioural disorderCephalalgia200525754554615955043
  • FuhJLWangSJDependent behavior in patients with medication-overuse headacheCurr Pain Headache Rep2012161737922125111
  • RadatFLanteri-MinetMWhat is the role of dependence-related behavior in medication-overuse headache?Headache201050101597161120807250
  • RossiPFaroniJVNappiGShort-term effectiveness of simple advice as a withdrawal strategy in simple and complicated medication overuse headacheEur J Neurol201118339640120629723
  • DienerHCDetoxification for medication overuse headache is not necessaryCephalalgia201232542342722127226
  • OlesenJDetoxification for medication overuse headache is the primary taskCephalalgia201232542042222174362
  • HagenKAlbretsenCVilmingSTManagement of medication overuse headache: 1-year randomized multicentre open-label trialCephalalgia200929222123218823363
  • Linton-DahlöfPLindeMDahlöfCWithdrawal therapy improves chronic daily headache associated with long-term misuse of headache medication: a retrospective studyCephalalgia200020765866211128824
  • KatsaravaZFritscheGMuessigMDienerHCLimmrothVClinical features of withdrawal headache following overuse of triptans and other headache drugsNeurology20015791694169811706113
  • KrymchantowskiAVMoreiraPFOut-patient detoxification in chronic migraine: comparison of strategiesCephalalgia2003231098299314984232
  • GrazziLAndrasikFUsaiSBussoneGIn-patient vs day-hospital withdrawal treatment for chronic migraine with medication overuse and disability assessment: results at one-year follow-upNeurol Sci200829Suppl 1S161S16318545923
  • Creac’hCFrappePCancadeMIn-patient versus out-patient withdrawal programmes for medication overuse headache: a 2-year randomized trialCephalalgia201131111189119821700646
  • GaulCBromstrupJFritscheGDienerHCKatsaravaZEvaluating integrated headache care: a one-year follow-up observational study in patients treated at the Essen headache centreBMC Neurol20111112421985562
  • BoeMGMyglandASalvesenRPrednisolone does not reduce withdrawal headache: a randomized, double-blind studyNeurology2007691263117475943
  • RabeKPagelerLGaulCPrednisone for the treatment of withdrawal headache in patients with medication overuse headache: a randomized, double-blind, placebo-controlled studyCephalalgia201333320220723093541
  • HagenKJensenRBoeMGStovnerLJMedication overuse headache: a critical review of end points in recent follow-up studiesJ Headache Pain201011537337720473701
  • GrandeRBAasethKBenthJSLundqvistCRussellMBReduction in medication-overuse headache after short information. The Akershus study of chronic headacheEur J Neurol201118112913720528911
  • RossiPDiLCFaroniJCesarinoFNappiGDi LorenzoCAdvice alone vs structured detoxification programmes for medication overuse headache: a prospective, randomized, open-label trial in transformed migraine patients with low medical needsCephalalgia20062691097110516919060
  • RossiPFaroniJVTassorelliCNappiGAdvice alone versus structured detoxification programmes for complicated medication overuse headache (MOH): a prospective, randomized, open-label trialJ Headache Pain20131411023565591
  • TassorelliCJensenRAllenaMA consensus protocol for the management of medication-overuse headache: evaluation in a multicentric, multinational studyCephalalgia Epub2014220
  • DienerHCDodickDWGoadsbyPJUtility of topiramate for the treatment of patients with chronic migraine in the presence or absence of acute medication overuseCephalalgia200929101021102719735529
  • DienerHCDodickDWAuroraSKOnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 2 trialCephalalgia201030780481420647171
  • AuroraSKDodickDWTurkelCCOnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 1 trialCephalalgia201030779380320647170
  • SandriniGPerrottaATassorelliCBotulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group studyJ Headache Pain201112442743321499747
  • SilbersteinSDBlumenfeldAMCadyRKOnabotulinumtoxinA for treatment of chronic migraine: PREEMPT 24-week pooled subgroup analysis of patients who had acute headache medication overuse at baselineJ Neurol Sci20133311–2485623790235
  • SarchielliPMessinaPCupiniLMSodium valproate in migraine without aura and medication overuse headache: a randomized controlled trialEur Neuropsychopharmacol Epub201445
  • ZeebergPOlesenJJensenRDiscontinuation of medication overuse in headache patients: recovery of therapeutic responsivenessCephalalgia200626101192119816961785
  • MartellettiPJensenRHAntalANeuromodulation of chronic headaches: position statement from the European Headache FederationJ Headache Pain20131418624144382
  • FreemanJATrentmanTLClinical utility of implantable neurostimulation devices in the treatment of chronic migraineMed Devices (Auckl)2013619520124348076
  • BoeMGSalvesenRMyglandAChronic daily headache with medication overuse: a randomized follow-up by neurologist or PCPCephalalgia200929885586319228151
  • GrazziLAndrasikFD’AmicoDUsaiSKassSBussoneGDisability in chronic migraine patients with medication overuse: treatment effects at 1-year follow-upHeadache200444767868315209690
  • KatsaravaZLimmrothVFinkeMDienerHCFritscheGRates and predictors for relapse in medication overuse headache: a 1-year prospective studyNeurology200360101682168312771266
  • KatsaravaZMuessigMDzagnidzeAFritscheGDienerHCLimmrothVMedication overuse headache: rates and predictors for relapse in a 4-year prospective studyCephalalgia2005251121515606564
  • Zidverc-TrajkovicJPekmezovicTJovanovicZMedication overuse headache: clinical features predicting treatment outcome at 1-year follow-upCephalalgia200727111219122517888081
  • BoeMGSalvesenRMyglandAChronic daily headache with medication overuse: predictors of outcome 1 year after withdrawal therapyEur J Neurol200916670571219236455
  • RossiPFaroniJVNappiGMedication overuse headache: predictors and rates of relapse in migraine patients with low medical needs. A 1-year prospective studyCephalalgia200828111196120018727648
  • AndrasikFGrazziLUsaiSKassSBussoneGDisability in chronic migraine with medication overuse: treatment effects through 5 yearsCephalalgia201030561061419614686
  • GhiottoNSancesGGalliFMedication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol)Cephalalgia200929223324319025549
  • LaiJTDereixJDGanepolaRPShould we educate about the risks of medication overuse headache?J Headache Pain2014151024524380
  • FritscheGFrettlohJHuppeMPrevention of medication overuse in patients with migrainePain2010151240441320800968