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Review

Caveolin-1: a multifaceted driver of breast cancer progression and its application in clinical treatment

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Pages 1539-1552 | Published online: 27 Feb 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Daniela Bizinelli, Fernanda Flores Navarro & Flavia Lima Costa Faldoni. (2022) Maca Root (Lepidium meyenii) Extract Increases the Expression of MMP-1 and Stimulates Migration of Triple-Negative Breast Cancer Cells. Nutrition and Cancer 74:1, pages 346-356.
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Jia-Hui Ye, Jia-Jun Shi, Xi Yin, Hong-Yan Wu, Xin-Yun Xu, Yong-Zhong Yao & Wei-Jie Zhang. (2020) Elevated Expression of CAV1 is Associated with Unfavorable Prognosis of Patients with Breast Cancer Who Undergo Surgery and Neoadjuvant Chemotherapy. Cancer Management and Research 12, pages 8887-8892.
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Articles from other publishers (39)

Sramana Bhowmick, Tannishtha Biswas, Mehnaz Ahmed, Debarshi Roy & Susmita Mondal. (2023) Caveolin-1 and lipids: Association and their dualism in oncogenic regulation. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:6, pages 189002.
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Simanti Pal, Betsy Reshma G, Franklin Pulikkottil Mohny, Srirupa Gupta Choudhury, Arundhati Karmakar, Sarika Gupta & Munia Ganguli. (2023) Albumin Nanoparticles Surface Decorated with a Tumor-Homing Peptide Help in Selective Killing of Triple-Negative Breast Cancer Cells. ACS Applied Materials & Interfaces 15:40, pages 46721-46737.
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Lulu Yang, Ying XiaoSiying Ren. (2023) Identification of common genetic features and pathways involved in pulmonary lymphangioleiomyomatosis and ER-positive breast cancer. Medicine 102:39, pages e34810.
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Qinyu Han, Shi Qiu, Huiwen Hu, Wenjing Li & Xiangqi Li. (2023) Role of Caveolae family-related proteins in the development of breast cancer. Frontiers in Molecular Biosciences 10.
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Terence M. Williams, Andreas Schneeweiss, Christian Jackisch, Changxian Shen, Karsten E. Weber, Peter A. Fasching, Carsten Denkert, Jenny Furlanetto, Ernst Heinmöller, Sabine Schmatloch, Thomas Karn, Christopher W. Szeto, Marion T. van Mackelenbergh, Valentina Nekljudova, Elmar Stickeler, Patrick Soon-Shiong, Christian Schem, Thomas Mairinger, Volkmar Müller, Frederik Marme, Michael Untch & Sibylle Loibl. (2023) Caveolin Gene Expression Predicts Clinical Outcomes for Early-Stage HER2-Negative Breast Cancer Treated with Paclitaxel-Based Chemotherapy in the GeparSepto Trial. Clinical Cancer Research 29:17, pages 3384-3394.
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Dharambir Kashyap, Amanjit Bal, Santosh Irinike, Siddhant Khare, Shalmoli Bhattacharya, Ashim Das & Gurpreet Singh. (2023) Heterogeneity of the Tumor Microenvironment Across Molecular Subtypes of Breast Cancer. Applied Immunohistochemistry & Molecular Morphology 31:8, pages 533-543.
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Nikola Zmarzły, Szymon Januszyk, Paweł Mieszczański, Justyna Czarniecka, Anna Bednarska-Czerwińska, Dariusz Boroń, Marcin Oplawski & Beniamin Oskar Grabarek. (2023) The influence of selected microRNAs on the expression profile of genes and proteins related to the tumor necrosis factor-alpha signaling pathways in endometrioid endometrial cancer. Journal of Cancer Research and Clinical Oncology 149:12, pages 9679-9689.
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Joanna Tobiasz & Joanna Polanska. (2023) Proteomic Profile Distinguishes New Subpopulations of Breast Cancer Patients with Different Survival Outcomes. Cancers 15:17, pages 4230.
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Michael Galogre, Dmitry Rodin, Mikhail Pyatnitskiy, Melissa Mackelprang & Igor Koman. (2023) A review of HER2 overexpression and somatic mutations in cancers. Critical Reviews in Oncology/Hematology 186, pages 103997.
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Aiswarya Chaudhuri, Dulla Naveen Kumar, Deepa Dehari, Rohit Patil, Sanjay Singh, Dinesh Kumar & Ashish Kumar Agrawal. (2023) Endorsement of TNBC Biomarkers in Precision Therapy by Nanotechnology. Cancers 15:9, pages 2661.
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Sanaa Hagag, Ahmad Kodous & HebatAllah Shaaban. (2023) Molecular and Immunohistochemical Alterations in Breast Cancer Patients in Upper Egypt. Reports of Biochemistry and Molecular Biology 11:4, pages 532-546.
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Luca Bertero, Alessandro Gambella, Antonella Barreca, Simona Osella-Abate, Luigi Chiusa, Paola Francia di Celle, Patrizia Lista, Mauro Papotti & Paola Cassoni. (2022) Caveolin-1 expression predicts favourable outcome and correlates with PDGFRA mutations in gastrointestinal stromal tumours (GISTs) . Journal of Clinical Pathology 75:12, pages 825-831.
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Dia Advani & Pravir Kumar. (2022) Deciphering the molecular mechanism and crosstalk between Parkinson's disease and breast cancer through multi-omics and drug repurposing approach. Neuropeptides 96, pages 102283.
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Mauriane Maja & Donatienne Tyteca. (2022) Alteration of cholesterol distribution at the plasma membrane of cancer cells: From evidence to pathophysiological implication and promising therapy strategy. Frontiers in Physiology 13.
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Qingyun Huang, Longyuan Wu, Yi Wang, Xinyu Kong, Xinhua Xiao, Qiyuan Huang, Miao Li, Yujia Zhai, Fuxiu Shi, Ruichen Zhao, Junpei Zhong & Lixia Xiong. (2022) Caveolin-1-deficient fibroblasts promote migration, invasion, and stemness via activating the TGF-β/Smad signaling pathway in breast cancer cells. Acta Biochimica et Biophysica Sinica 54:11, pages 1587-1598.
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Fuxiu Shi, Xinyue Chen, Yi Wang, Yujie Xie, Junpei Zhong, Kangtai Su, Miao Li, Yuqiu Li, Qing Lin, Youjia Zhou, Jie Wang & Lixia Xiong. (2022) HOTAIR/miR-203/CAV1 Crosstalk Influences Proliferation, Migration, and Invasion in the Breast Cancer Cell. International Journal of Molecular Sciences 23:19, pages 11755.
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Douglas Howard, Tyron Turnbull, David J. Paterson, Benjamin Thierry & Ivan Kempson. (2022) Cell Size as a Primary Determinant in Targeted Nanoparticle Uptake. ACS Applied Bio Materials 5:9, pages 4222-4231.
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Hongxian Wang, Lirong Shu, Nan Niu, Chenyang Zhao, Shuqi Lu, Yanhua Li, Huanyu Wang, Yao Liu, Tianhui Zou, Jiawei Zou, Xiaoqin Wu & Yun Wang. (2022) Novel lncRNAs with diagnostic or prognostic value screened out from breast cancer via bioinformatics analyses. PeerJ 10, pages e13641.
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Dengdi Hu, Zhaoqing Li, Bin Zheng, Xixi Lin, Yuehong Pan, Peirong Gong, Wenying Zhuo, Yujie Hu, Cong Chen, Lini Chen, Jichun Zhou & Linbo Wang. (2022) Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities. Cancer Communications 42:5, pages 401-434.
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Johnathan Abou-FadelMuaz BhalliBrian GrajedaJun Zhang. (2022) CmP Signaling Network Leads to Identification of Prognostic Biomarkers for Triple-Negative Breast Cancer in Caucasian Women. Genetic Testing and Molecular Biomarkers 26:4, pages 198-219.
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Yiling Guo, Yujia Zhai, Longyuan Wu, Yazhuo Wang, Puzhen Wu & Lixia Xiong. (2022) Mesenchymal Stem Cell-Derived Extracellular Vesicles: Pleiotropic Impacts on Breast Cancer Occurrence, Development, and Therapy. International Journal of Molecular Sciences 23:6, pages 2927.
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Lie Yuan, Yongqing Cai, Liang Zhang, Sijia Liu, Pan Li & Xiaoli Li. (2022) Promoting Apoptosis, a Promising Way to Treat Breast Cancer With Natural Products: A Comprehensive Review. Frontiers in Pharmacology 12.
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Xingning Lai, Yiling Guo, Miaomiao Chen, Yuxuan Wei, Wanting Yi, Yubo Shi & Lixia Xiong. (2021) Caveolin1: its roles in normal and cancer stem cells. Journal of Cancer Research and Clinical Oncology 147:12, pages 3459-3475.
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Naiade Calanca, Sara Martoreli Silveira Binato, Sabrina Daniela da Silva, Helena Paula Brentani, Luiz Ubirajara Sennes, Clóvis Antonio Lopes Pinto, Maria Aparecida Custódio Domingues, Carlos Eduardo Fonseca-Alves, Claudia Aparecida Rainho & Silvia Regina Rogatto. (2021) Master Regulators of Epithelial-Mesenchymal Transition and WNT Signaling Pathways in Juvenile Nasopharyngeal Angiofibromas. Biomedicines 9:9, pages 1258.
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Jesusa Capera, Mireia Pérez-Verdaguer, Roberta Peruzzo, María Navarro-Pérez, Juan Martínez-Pinna, Armando Alberola-Die, Andrés Morales, Luigi Leanza, Ildiko Szabó & Antonio Felipe. (2021) A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis. eLife 10.
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Joana Godinho-Pereira, Ana Rita Garcia, Inês Figueira, Rui Malhó & Maria Alexandra Brito. (2021) Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood–Brain Barrier Disruption. International Journal of Molecular Sciences 22:13, pages 7057.
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María Paz Saldías, Diego Maureira, Octavio Orellana-Serradell, Ian Silva, Boris Lavanderos, Pablo Cruz, Camila Torres, Mónica Cáceres & Oscar Cerda. (2021) TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer. Frontiers in Oncology 11.
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Hryhorii Chereda, Annalen Bleckmann, Kerstin Menck, Júlia Perera-Bel, Philip Stegmaier, Florian Auer, Frank Kramer, Andreas Leha & Tim Beißbarth. (2021) Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer. Genome Medicine 13:1.
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Fayola Levine & Olorunseun O. Ogunwobi. (2021) Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin—Low Triple Negative Breast Cancer Cells. Cancers 13:5, pages 1046.
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Joshua D. Greenlee, Tejas Subramanian, Kevin Liu & Michael R. King. (2021) Rafting Down the Metastatic Cascade: The Role of Lipid Rafts in Cancer Metastasis, Cell Death, and Clinical Outcomes. Cancer Research 81:1, pages 5-17.
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Neng Wang, Gulizeba Muhetaer, Xiaotong Zhang, Bowen Yang, Caiwei Wang, Yu Zhang, Xuan Wang, Juping Zhang, Shengqi Wang, Yifeng Zheng, Fengxue Zhang & Zhiyu Wang. (2020) Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling. Frontiers in Pharmacology 11.
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Yamin Yang, Sijia Liu, Chunxiao Chen, Haipeng Huang, Ling Tao, Zhiyu Qian & Weitao Li. (2020) Microfluidic-enabled self-organized tumor model for in vitro cytotoxicity assessment of doxorubicin. Biomedical Microdevices 22:4.
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Antonella Romano, Antonia Feola, Antonio Porcellini, Vincenzo Gigantino, Maurizio Di Bonito, Annabella Di Mauro, Rocco Caggiano, Raffaella Faraonio & Candida Zuchegna. (2020) Estrogen Induces Selective Transcription of Caveolin1 Variants in Human Breast Cancer through Estrogen Responsive Element-Dependent Mechanisms. International Journal of Molecular Sciences 21:17, pages 5989.
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Fidel Nicolás Lolo, Víctor Jiménez-Jiménez, Miguel Sánchez-Álvarez & Miguel Ángel del Pozo. (2020) Tumor-stroma biomechanical crosstalk: a perspective on the role of caveolin-1 in tumor progression. Cancer and Metastasis Reviews 39:2, pages 485-503.
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Vibha Singh & Christophe Lamaze. (2020) Membrane tension buffering by caveolae: a role in cancer?. Cancer and Metastasis Reviews 39:2, pages 505-517.
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Yuyang Zeng, Mengxi Chen, Sridha Ganesh, Shunze Hu & Honglei Chen. (2020) Clinicopathological and prognostic significance of caveolin-1 and ATG4C expression in the epithelial ovarian cancer. PLOS ONE 15:5, pages e0232235.
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Ilja L. Kruglikov, Zhuzhen Zhang & Philipp E. Scherer. (2019) Caveolin-1 in skin aging – From innocent bystander to major contributor. Ageing Research Reviews 55, pages 100959.
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